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Modified Checklist for Autism in Toddlers

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61. Treatment of Depression During Pregnancy and the Postpartum Period

length of stay o Infant attachment o Developmental screening—Ages and Stages Questionnaire; Denver; Modified Checklist for Autism in Toddlers; Bayley Scales of Infant Development • Growth and development after 1 year of age: o Developmental screening and diagnoses o Growth parameters (height, weight, and body mass index percentile according to sex and age) • Learning (e.g., linguistic, cognitive, and social-emotional skills) and educational achievement o Kindergarten readiness o Age at Kindergarten (...) in quality. As the fair-quality category is broad, studies with this rating vary in their strengths and weaknesses: The results of some fair-quality studies are likely to be valid, while others are only possibly valid. A poor- quality study is not valid; the results are at least as likely to reflect flaws in the study design as a true difference between the compared interventions. A fatal flaw is reflected by failure to meet combinations of items of the quality assessment checklist. All studies

2014 Effective Health Care Program (AHRQ)

62. Umbilical Cord Milking in Non-Vigorous Infants Developmental Followup (MINVIFU)

[ Time Frame: 22-26 months ] Overall and Domain Scores - Ages and Stages, 3rd ed. Questionnaire Secondary Outcome Measures : Autism Outcome [ Time Frame: 22-26 months ] Modified Checklist for Autism in Toddlers (M-CHAT-R) Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor (...) Intervention Model Description: Neurodevelopmental assessments will be done at 2 years of corrected age (22-26 months) for subjects who were randomized to receive either early cord clamping or umbilical cord milking as part of the MINVI trial. Masking: Single (Outcomes Assessor) Masking Description: Neurodevelopmental providers will be blinded to the randomization of the toddler during the examination. Primary Purpose: Diagnostic Official Title: Umbilical Cord Milking in Non-Vigorous Infants Developmental

2018 Clinical Trials

63. Stockholm Preterm Interaction-Based Intervention

on a 3-point scale, 5 questions of prosocial behaviour and 20 questions about various difficulties. Hypothesis of higher scores in the intervention group for prosocial behaviour and lower scores in the intervention group of the problematic subscales. Child's autistic symptoms [ Time Frame: 24 months corrected age ] Modified checklist for autism in toddlers M-CHAT. Range 0-20 points, hypothesis of lower scores in intervention group. Infant temperament [ Time Frame: 12 months corrected age ] Infant (...) ; sensitivity, structure, non-intrusiveness, non-hostility and two child dimensions; child responsiveness and child involvement. Each subscale has a maximum score of 29 and a direct score of 1-7. Hypothesis of higher scores in intervention group. Secondary Outcome Measures : Child's general development [ Time Frame: 24 months corrected age ] Bayley scales of infant and toddler development (third edition; Bayley-III), measuring cognition, language, and motor development. Composite scores are standardized

2018 Clinical Trials

64. Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU)

of age [ Time Frame: 3-5 months ] Assessment of Fidgety Movements by Prechtl's method Neurodevelopmental Outcome at 1 Year of Age [ Time Frame: 10-14 months ] Developmental Activities Screening Inventory - Second Edition (DASI-II) Autism Outcome [ Time Frame: 22-26 months ] Modified Checklist for Autism in Toddlers (M-CHAT-R) Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor (...) milking as part of the MIDAB trial. Masking: Single (Outcomes Assessor) Masking Description: Neurodevelopmental providers will be blinded to the randomization of the toddler during the examination. Primary Purpose: Supportive Care Official Title: Long-term Outcomes of Umbilical Cord Milking in Term and Late Preterm Neonates Who Are Depressed at Birth Estimated Study Start Date : October 1, 2018 Estimated Primary Completion Date : May 30, 2020 Estimated Study Completion Date : May 30, 2022 Resource

2018 Clinical Trials

65. Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. (PubMed)

March 1, 2016, through June 13, 2017.Maternal folic acid supplementation 4 weeks before to 12 weeks after conception. Plasma folate concentration was analyzed at gestational weeks 17 to 19.Autistic traits were evaluated using the Modified Checklist for Autism in Toddlers and Social Communication Questionnaire. Odds ratios (ORs) for autistic traits in children by maternal use vs nonuse of folic acid supplements were adjusted for maternal health and socioeconomic factors. Folate concentrations (...) Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero. Strategies to prevent autism in children exposed to antiepileptic drugs (AEDs) during pregnancy are important.To explore whether folic acid supplementation and folate status in pregnancy are associated with reduced risk of autistic traits owing to in utero AED exposure.The population-based, prospective Norwegian Mother and Child Cohort Study approached

2017 JAMA neurology

66. Family Nurture Intervention in the NICU at The Valley Hospital

. The CBCL consists of 100 items. This will be administered at the 18 Months CA Follow-Up. Modified Checklist for Autism in Toddlers (M-CHAT) Score [ Time Frame: Up to 18 months ] The M-CHAT is a questionnaire validated for screening toddlers to assess risk for autism spectrum disorders (ASD). It is a 23 yes/no item questionnaire administered to the mother which can be scored in less than 2 minutes. This will be administered at the 18 Month CA Follow-Up. Eligibility Criteria Go to Information from (...) by unavoidable real-life stressors. The T-Anxiety scale has proven useful for identifying persons who differ in motivation or drive level. The STAI has been used in studies examining parents of hospitalized children, the transition to a maternal role, perception of illness severity in infants, and maternal anxiety during pregnancy and fetal attachment. Neurobehavioral Assessments of Infants - Bayley Scales or Infant and Toddler Development, Bayley III [ Time Frame: Up to 18 months ] At the 18 month corrected

2017 Clinical Trials

67. Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders

communication and sensory reactivity in infants at-risk for autism and other NDs on the one hand, and parent responses to infant cues on the other hand, using live coaching and video feedback methods. Other Name: PIE Experimental: SR followed by PC Parents will be coached for 6 weekly sessions in the Parents and Infants Engaged (PIE) intervention sensory reactions (SR) domain to identify their child's sensory reactions to daily activities and respond to those reactions or modify the environment in ways (...) /treatment Phase Autism Spectrum Disorder Neurodevelopmental Disorders Behavioral: Parents and Infants Engaged Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 44 participants Allocation: Randomized Intervention Model: Crossover Assignment Intervention Model Description: The intervention phases of the study will use a randomized comparative trial design, with two phases. For Study Phase 1, dyads will participate

2017 Clinical Trials

68. PAEAN

years of age ] Hearing impairment status by paediatric examination - requirement for hearing aids [ Time Frame: 2 years of age ] Autism spectrum disorder, assessed by Modified Checklist for Autism in Toddlers (M-CHAT) parent questionnaire [ Time Frame: 2 years of age ] Epilepsy (history of 2 or more afebrile unprovoked seizures since discharge from neonatal unit where PAEAN study treatment was provided, or use of anticonvulsants at 2 years of age). [ Time Frame: 2 years of age ] Cost of healthcare (...) blood obtained at less than 60 minutes after birth, either pH less than 7.00 OR base deficit greater than or equal to 12.0 mmol/L Moderate to severe encephalopathy, defined between one and six hours after birth by one or both of the following: 3 out of 6 modified Sarnat criteria indicating moderate/severe encephalopathy, OR 2 out of 6 modified Sarnat criteria plus seizure(s) requiring anticonvulsant treatment (diagnosed either clinically or using EEG monitoring) at any time prior to randomisation

2017 Clinical Trials

69. The 3D Cohort Study (Design, Develop, Discover)

: Sensory Profile questionnaire. This test was done on 1520 children. Neurodevelopment - MacArthur-Bates [ Time Frame: When infants are 2 years old ] Neurodevelopmental assessment of the infant. Test used : MacArthur Communicative Development Inventories (CDI; French, English, Spanish and/or Mandarin). This test was done on 1520 children. Neurodevelopment - M-CHAT [ Time Frame: When infants are 2 years old ] Neurodevelopmental assessment of the infant. Test used : Modified Checklist of Autism (...) . Test used : Bayley Scales of Infant and Toddler Development (BSID‐III; cognitive scale and motor scale combined). This test was done on 1520 children. Neurodevelopment - ABAS [ Time Frame: When infants are 2 years old ] Neurodevelopmental assessment of the infant. Test used : Bayley Adaptive Behaviour Questionnaire (ABAS‐II). This test was done on 1520 children. Neurodevelopment - Sensory Profile [ Time Frame: When infants are 2 years old ] Neurodevelopmental assessment of the infant. Test used

2017 Clinical Trials

70. Sensory defects and developmental delay among children with congenital rubella syndrome (PubMed)

spectrum disorder (ASD) in 2013 by the Modified Checklist for Autism in Toddlers. In 2015, proportions of children failing the problem-solving (62%) and personal-social (62%) domains had increased and two of 13 were diagnosed with ASD by the Childhood Autism Rating Scale, Second Edition. Developmental difficulties were suspected in most children with CRS, including autism largely combined with sensory dysfunction. (...) from 2013 to 2015. Thirteen and seven participants had hearing and functional ophthalmological impairment, respectively. Developmental difficulties were suspected in 19 (95%) children who failed in at least one area of the Ages and Stages Questionnaire (ASQ) and/or Denver II in 2013 and/or 2015. Developmental difficulties were frequently identified in the ASQ communication domain (n = 14 in 2013) and Denver II language area (n = 13 in 2013). Seven (41%) participants were suspected of having autism

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2017 Scientific reports

71. Usefulness of the Korean Developmental Screening Test for infants and children for the evaluation of developmental delay in Korean infants and children: a single-center study (PubMed)

Autism Rating Scale (CARS), Modified Checklist for Autism in Toddlers (M-CHAT), electroencephalography, magnetic resonance imaging, and extensive tests conducted in 209 of 1,403 patients, of whom 758 underwent the K-DST at the Korea University Guro Hospital between January 2015 and December 2016 and 645 were referred from local clinics between January 2015 and June 2016.Based on the K-DST results, the male children significantly more frequently required further or follow-up examination than (...) the female children in most test sections, except for gross motor. The male children had notably lower mean scores than the female children. The PRES/SELSI results showed that when more further or follow-up evaluations were required in the K-DST communication section, significantly more problems in language delay or disorder emerged. When further or follow-up evaluation was required in the cognitive section in the CARS/M-CHAT, the possibility of autism increased significantly. A child tended to score low

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2017 Korean journal of pediatrics

72. Neurodevelopmental Outcomes in Children With Congenital Heart Disease: Evaluation and Management

or developmental delay. Table 4. Domains and Suggested Instruments for Developmental Evaluation of Children and Adolescents With CHD Age-Specific Measurement Age Evaluation Component Examples Infant (birth to 1 y) Developmental history Growth Feeding history Neuromotor examination Audiologic examination Toddler (1 to 3.5 y) Standardized developmental measure • Bayley Scales of Infant Development–III • Mullen Scales of Early Learning Behavior parent report • Child Behavior Checklist • Brief Infant-Toddler (...) 3.3.3.2. Autism Spectrum Disorders 1156 3.3.3.3. Fine and Gross Motor Skills 1156 3.4. Make Referrals for Early Intervention and Formal Developmental and Medical Evaluation 1157 3.5. Formal Developmental and Medical Evaluation 1157 3.5.1. Individualized Approach 1157 3.5.2. Genetic Evaluation 1157 3.5.2.1. Early Identification 1157 3.5.2.2. Latent and Subtle Phenotypes 1158 3.5.2.3. Specialized or Advanced Analyses 1158 3.5.3. Structural Brain Imaging 1158 3.5.4. Age-specific Neurodevelopmental

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2012 American Heart Association

73. Family Nurture Intervention in the NICU

/facial gestures on independent 3-point scales. Child Behavior Checklist Score [ Time Frame: 18 Month corrected age Follow-Up ] The Child Behavior Checklist (CBCL) is a device by which parents rate a child's problem behaviors and competencies. The CBCL can also be used to measure a child's change in behavior over time or following a treatment. The CBCL consists of 100 items. Modified Checklist for Autism in Toddlers (M-CHAT) Score [ Time Frame: 18 Month corrected age Follow-Up ] The M-CHAT (...) is a questionnaire validated for screening toddlers to assess risk for autism spectrum disorders (ASD). It is a 23 yes/no item questionnaire administered to the mother which can be scored in less than two minutes. The investigators will administer the M-CHAT during the 18 month follow up visit. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join

2016 Clinical Trials

74. Rates of detection of developmental problems at the 18-month well-baby visit by family physicians' using four evidence-based screening tools compared to usual care: a randomized controlled trial. (PubMed)

), the PEDS-Developmental Milestones (PEDS-DM), the Modified Checklist for Autism in Toddlers (M-CHAT) and PHQ9 (maternal depression).In the 'usual care' group four (16%) and in the evidence-based tools group 18 (62%) were identified as having a possible developmental problem. In the evidence-based tools group three infants were to be recalled at 24 months for language checks (no specialist referrals made). In the 'usual care' group four problems were identified: one child was referred for speech therapy

2016 Child: care, health and development

75. Identification of Characteristics Associated With Symptom Remission in Autism

, developmental psychologist, child clinical psychologist, or a child psychiatrist measure of cognitive ability from within 1 year of initial autism diagnosis objective measure indicative of prominent autism symptoms using a recognized and standardized assessment of autism symptoms such as the Social Responsiveness Scale (SRS), Childhood Autism Rating Scale (CARS), or the Modified Checklist for Autism in Toddlers (MCHAT) or video tapes of assessments initial diagnosis of autism prior to age 6 AND Medical (...) Identification of Characteristics Associated With Symptom Remission in Autism Identification of Characteristics Associated With Symptom Remission in Autism - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2009 Clinical Trials

76. Efficacy of the START-Play Program for Infants With Neuromotor Disorders

and Toddler Development -Third Edition for problem solving and global development. Secondary measures include additional measures of postural control and reaching, child and family characteristics, and fidelity of implementation (logs and checklist). Data Analytic Strategy: The investigators will use linear mixed modeling (LMM) to determine the efficacy of the intervention on child outcomes. Parallel process growth modeling within a structural equation modeling framework will be used to examine whether (...) Outcome Measures Go to Primary Outcome Measures : Change in Bayley Scales of Infant Development III [ Time Frame: Baseline, after 6 weeks, at end of 3 month intervention, and at 3 and 9 months follow-up ] Global developmental skills Secondary Outcome Measures : Change in Modified Parent Child Interaction-Dyadic Mini Code [ Time Frame: Baseline, after 6 weeks, at end of 3 month intervention, and at 3 and 9 months follow-up ] Play and interaction of parent and child Change in Postural measure of trunk

2015 Clinical Trials

77. Testing the Effectiveness of Telephone-based Early Childhood Developmental Screening

Evaluation of Developmental Status (PEDS), the PEDS: Developmental Milestones (PEDS:DM), the Ages and Stages Questionnaires (ASQ), and/or the Modified Checklist for Autism in Toddlers (MCHAT), Revised version. Referrals made [ Time Frame: 6 months ] Based on medical record review, parent report, and 211 data, we will measure whether any referrals were made for children with developmental or behavioral concerns, for evaluation or services. Services received [ Time Frame: 6 months ] Based on medical record (...) Study Completion Date : February 28, 2017 Arms and Interventions Go to Arm Intervention/treatment Experimental: Telephone-based screening Families randomized to the intervention arm will be connected with 211 Los Angeles for completion of developmental screening over the phone. Screening will consist of three structured, validated, parent-report tools: the Parental Evaluation of Developmental Status (PEDS), the PEDS Developmental Milestones (PEDS:DM), and the Modified Checklist for Autism

2015 Clinical Trials

78. An SRT Model for Early Access to ASD Intervention

) expedited ASD assessments within EI programs; and (3) use of an inexpensive, evidence-based ASD-specialized intervention by EI providers. An electronic version of the Modified Checklist for Autism (M-CHAT) with automated scoring that incorporates relevant follow-up questions will be provided to PCP practices, and distance coaching via telemedicine will be available to EI providers to support their ASD assessment and intervention activities. A stepped wedge cluster RCT design will be used to evaluate (...) Children's Hospital National Institute of Mental Health (NIMH) Information provided by (Responsible Party): Wendy Stone, University of Washington Study Details Study Description Go to Brief Summary: This project will implement and evaluate an innovative healthcare service delivery model designed to promote earlier access to specialized intervention for toddlers with ASD. The Screen-Refer-Treat (SRT) model provides a coordinated and cost-effective approach to early identification and intervention

2015 Clinical Trials

79. Family Nurture Intervention in the Neonatal Intensive Care Unit improves social-relatedness, attention, and neurodevelopment of preterm infants at 18 months in a randomized controlled trial. (PubMed)

on neurobehavioral outcomes.Data were collected at 18 months corrected age from preterm infants. Infants were assigned at birth to FNI or standard care (SC). Bayley Scales of Infant Development III (Bayley-III) were assessed for 76 infants (SC, n = 31; FNI, n = 45); the Child Behavior Checklist (CBCL) for 57 infants (SC, n = 31; FNI, n = 26); and the Modified Checklist for Autism in Toddlers (M-CHAT) was obtained for 59 infants (SC, n = 33; FNI, n = 26).Family Nurture Intervention significantly improved Bayley

2015 Journal of Child Psychology and Psychiatry

80. The breadth and type of systemic inflammation and the risk of adverse neurological outcomes in extremely low gestational age newborns (PubMed)

, impaired early cognitive functioning, cerebral palsy, and autism risk as assessed with the Modified Checklist for Autism in Toddlers screen, and in a subset of these children from 12 of 14 sites (n = 826), an attention problem identified with the Child Behavior Checklist.The risk of abnormal brain structure and function overall was increased among children who had recurrent and/or persistent elevations of the 25 proteins. The risk for most outcomes did not rise until at least four proteins in at least (...) two functional categories were elevated. When we focused our analysis on 10 proteins previously found to be associated consistently with neurological outcomes, we found the risk of low Mental Development Index on the Bayley Scales of Infant Development-II, microcephaly, and a Child Behavior Checklist-defined attention problem increased with higher numbers of these recurrently and/or persistently elevated proteins.Increasing breadth of early neonatal inflammation, indexed by the number of protein

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2014 Pediatric Neurology

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