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Modified Checklist for Autism in Toddlers

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1. Use of a Digital Modified Checklist for Autism in Toddlers - Revised with Follow-up to Improve Quality of Screening for Autism. (PubMed)

Use of a Digital Modified Checklist for Autism in Toddlers - Revised with Follow-up to Improve Quality of Screening for Autism. To assess changes in quality of care for children at risk for autism spectrum disorders (ASD) due to process improvement and implementation of a digital screening form.The process of screening for ASD was studied in an academic primary care pediatrics clinic before and after implementation of a digital version of the Modified Checklist for Autism in Toddlers - Revised (...) results increased from 54% to 92% (38% increase, 95% CI 14%-64%) and appropriate action for children screening positive increased from 25% to 85% (60% increase, 95% CI 35%-85%). A total of 90% of participating physicians agreed that the transition to a digital screening form improved their clinical assessment of autism risk.Implementation of a tablet-based digital version of the Modified Checklist for Autism in Toddlers - Revised with Follow-up led to improved quality of care for children at risk

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2017 Journal of Pediatrics

2. Assessing the accuracy of the Modified Checklist for Autism in Toddlers: a systematic review and meta-analysis. (PubMed)

Assessing the accuracy of the Modified Checklist for Autism in Toddlers: a systematic review and meta-analysis. The Modified Checklist for Autism in Toddlers (M-CHAT) could be appropriate for universal screening for autism spectrum disorder (ASD) at 18 months and 24 months. Validation studies, however, reported differences in psychometric properties across sample populations. This meta-analysis summarized its accuracy measures and quantified their change in relation to patient and study (...) score.The Modified Checklist for Autism in Toddlers (M-CHAT) performs with low-to-moderate accuracy in children with developmental concerns. There is limited evidence supporting its use at 18 months or in low-risk children.© 2018 Mac Keith Press.

2018 Developmental Medicine and Child Neurology

3. Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm

Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm To examine the predictive validity of the Modified Checklist for Autism in Toddlers (M-CHAT) administered at age 24 months for autism spectrum disorder (ASD) diagnosed at 10 years of age in a US cohort of 827 extremely low gestational age newborns (ELGANs) followed from birth.We examined the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the M-CHAT (...) -positive rates also were associated with lower SES, motor and cognitive impairments, and emotional/behavioral dysregulation at age 2 years.Among extremely preterm children with ASD, almost one-half were not correctly screened by the M-CHAT at age 2 years. Sensorimotor and cognitive impairments, SES, and emotional/behavioral dysregulation contributed significantly to M-CHAT misclassifications. Clinicians are advised to consider these factors when screening very preterm toddlers for ASD.Copyright © 2016

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2016 EvidenceUpdates

4. Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm. (PubMed)

Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm. To examine the predictive validity of the Modified Checklist for Autism in Toddlers (M-CHAT) administered at age 24 months for autism spectrum disorder (ASD) diagnosed at 10 years of age in a US cohort of 827 extremely low gestational age newborns (ELGANs) followed from birth.We examined the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the M-CHAT (...) -positive rates also were associated with lower SES, motor and cognitive impairments, and emotional/behavioral dysregulation at age 2 years.Among extremely preterm children with ASD, almost one-half were not correctly screened by the M-CHAT at age 2 years. Sensorimotor and cognitive impairments, SES, and emotional/behavioral dysregulation contributed significantly to M-CHAT misclassifications. Clinicians are advised to consider these factors when screening very preterm toddlers for ASD.Copyright © 2016

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2016 Journal of Pediatrics

5. Modified Checklist for Autism in Toddlers

Modified Checklist for Autism in Toddlers Modified Checklist for Autism in Toddlers Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Modified Checklist for Autism in Toddlers Modified Checklist for Autism in Toddlers Aka: Modified Checklist for Autism in Toddlers , M-CHAT Questionnaire , M-CHAT From Related Chapters II. Indications Screening for ages 16-48 months Recommended for periodic screening at 18 and 24 months III. Description Parent completes 23 question survey in 5-10 minute period Six critical questions Referral indicated if child fails more than 3 items total or 2 critical items IV. Background Developed by Robins, Fein

2018 FP Notebook

6. Serbian Language version of the Modified Checklist for Autism in Toddlers, Revised, with Follow-Up: Cross-Cultural Adaptation and Assessment of Reliability (PubMed)

Serbian Language version of the Modified Checklist for Autism in Toddlers, Revised, with Follow-Up: Cross-Cultural Adaptation and Assessment of Reliability Early detection of Autism Spectrum Disorder (ASD) has proven to be of high significance, however there is a limited availability of ASD screening tools in Serbian language. In this study we aim to translate, assess reliability and, in part, test the applicability of Modified Checklist for Autism in Toddlers, Revised, with Follow-Up (M-CHAT R

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2016 Scientific reports

7. Validation of the modified checklist for Autism in toddlers, revised with follow-up (M-CHAT-R/F) (PubMed)

Validation of the modified checklist for Autism in toddlers, revised with follow-up (M-CHAT-R/F) This study validates the Modified Checklist for Autism in Toddlers, Revised with Follow-up (M-CHAT-R/F), a screening tool for low-risk toddlers, and demonstrates improved utility compared with the original M-CHAT.Toddlers (N = 16,071) were screened during 18- and 24-month well-child care visits in metropolitan Atlanta and Connecticut. Parents of toddlers at risk on M-CHAT-R completed follow-up (...) ; those who continued to show risk were evaluated.The reliability and validity of the M-CHAT-R/F were demonstrated, and optimal scoring was determined by using receiver operating characteristic curves. Children whose total score was ≥ 3 initially and ≥ 2 after follow-up had a 47.5% risk of being diagnosed with autism spectrum disorder (ASD; confidence interval [95% CI]: 0.41-0.54) and a 94.6% risk of any developmental delay or concern (95% CI: 0.92-0.98). Total score was more effective than

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2014 EvidenceUpdates

8. Use of the Modified Checklist for Autism, Revised with Follow up-Albanian to Screen for ASD in Albania (PubMed)

Use of the Modified Checklist for Autism, Revised with Follow up-Albanian to Screen for ASD in Albania The Modified Checklist for Autism in Toddlers Revised-Albanian screener (M-CHAT-R-A) was used to screen 2594 toddlers, aged 16-30 months, at well-child visits. Two hundred fifty-three (9.75 %) screened positive; follow up on failed items were conducted by phone with 127 (50 %); the remainder were lost to follow-up. Twenty-six toddlers (21 %) continued to screen positive; 19 received full (...) evaluations, which assessed for ASD with the Autism Diagnostic Observation Schedule and developmental delays with the Parents Assessment of Developmental Status-Developmental Milestones. All evaluated children had significant delays; 17 of the 19 met criteria for Autism/ASD. Removal of three items improved performance. Although Albania and the US are quite different in culture and language, key features of ASD appeared very similar.

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2016 Journal of autism and developmental disorders

9. Large-scale use of the modified checklist for autism in low-risk toddlers. (PubMed)

Large-scale use of the modified checklist for autism in low-risk toddlers. The purpose of the study was to examine use of the Modified Checklist for Autism in Toddlers (M-CHAT) as an autism-specific screening instrument in a large, geographically diverse pediatrics-based sample.The M-CHAT and the M-CHAT Follow-Up (M-CHAT/F) were used to screen 18,989 toddlers at pediatric well-child visits in 2 US geographic regions. Pediatricians directly referred children to ascertain potential missed (...) screening cases. Screen-positive children received the M-CHAT/F; children who continued to screen positive after the M-CHAT/F received a diagnostic evaluation.Results indicated that 54% of children who screened positive on the M-CHAT and M-CHAT/F presented with an autism spectrum disorder (ASD), and 98% presented with clinically significant developmental concerns warranting intervention. An M-CHAT total score cutoff of ≥3 identifies nearly all screen-positive cases, and for ease of scoring the use

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2013 Pediatrics

10. Validation of the Modified Checklist for Autism in Toddlers, Revised With Follow-up (M-CHAT-R/F). (PubMed)

Validation of the Modified Checklist for Autism in Toddlers, Revised With Follow-up (M-CHAT-R/F). This study validates the Modified Checklist for Autism in Toddlers, Revised with Follow-up (M-CHAT-R/F), a screening tool for low-risk toddlers, and demonstrates improved utility compared with the original M-CHAT.Toddlers (N = 16,071) were screened during 18- and 24-month well-child care visits in metropolitan Atlanta and Connecticut. Parents of toddlers at risk on M-CHAT-R completed follow-up (...) ; those who continued to show risk were evaluated.The reliability and validity of the M-CHAT-R/F were demonstrated, and optimal scoring was determined by using receiver operating characteristic curves. Children whose total score was ≥ 3 initially and ≥ 2 after follow-up had a 47.5% risk of being diagnosed with autism spectrum disorder (ASD; confidence interval [95% CI]: 0.41-0.54) and a 94.6% risk of any developmental delay or concern (95% CI: 0.92-0.98). Total score was more effective than

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2013 Pediatrics

11. A possible role of the Infant/Toddler Sensory Profile in screening for autism: a proof-of-concept study in the specific sample of prematurely born children with birth weights <1,500 g (PubMed)

a screening battery that included the ITSP, Modified Checklist for Autism in Toddlers (M-CHAT), and the Communication and Symbolic Behavior Scales Developmental Profile Infant-Toddler Checklist (CSBS-DP-ITC). Children with known disabilities were excluded. All the children who were screened positive on any of the screening tools subsequently underwent clinical examination including the Autism Diagnostic Observation Schedule.We used classification trees to answer the question whether ITSP (or some of its (...) A possible role of the Infant/Toddler Sensory Profile in screening for autism: a proof-of-concept study in the specific sample of prematurely born children with birth weights <1,500 g The objective of this study was to explore the potential of the Infant/Toddler Sensory Profile (ITSP) as a screening tool for autism spectrum disorders (ASD) in prematurely born children.Parents of 157 children with birth weights <1,500 g (aged 2 years, corrected for prematurity; 88 boys, 69 girls) completed

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2017 Neuropsychiatric disease and treatment

12. Modified Checklist for Autism in Toddlers

Modified Checklist for Autism in Toddlers Modified Checklist for Autism in Toddlers Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Modified Checklist for Autism in Toddlers Modified Checklist for Autism in Toddlers Aka: Modified Checklist for Autism in Toddlers , M-CHAT Questionnaire , M-CHAT From Related Chapters II. Indications Screening for ages 16-48 months Recommended for periodic screening at 18 and 24 months III. Description Parent completes 23 question survey in 5-10 minute period Six critical questions Referral indicated if child fails more than 3 items total or 2 critical items IV. Background Developed by Robins, Fein

2015 FP Notebook

13. Autism in Toddlers Born Very Preterm. (PubMed)

Autism in Toddlers Born Very Preterm. This study aimed to determine the prevalence of autism spectrum disorder (ASD) by using the Autism Diagnostic Observation Schedule-Generic (ADOS-G) classifications in children born very preterm during their toddler years.Two birth cohorts of toddlers (2 and 4 years old) each recruited over 12 months and born at <29 weeks' gestation were administered the Modified Checklist of Autism in Toddlers-Follow-up Interview (M-CHAT-FI) screen, the ADOS-G (...) , and developmental assessments. The ADOS-G was conducted on toddlers with M-CHAT-FI-positive screens.Data were available on 88% (169/192) of children. In total, 22 (13%) toddlers screened positive and 3 (1.8%) were confirmed diagnostically with ASD. These 3 cases reached the highest ADOS-G threshold classification of autism. All but 1 child who scored below the ADOS-G thresholds (11/12) demonstrated some difficulty with social communication. Risk was significantly increased for co-occurring neurodevelopmental

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2016 Pediatrics

14. The Modified Checklist for Autism in Toddlers in extremely low gestational age newborns: individual items associated with motor, cognitive, vision and hearing limitations. (PubMed)

The Modified Checklist for Autism in Toddlers in extremely low gestational age newborns: individual items associated with motor, cognitive, vision and hearing limitations. The Modified Checklist for Autism in Toddlers (M-CHAT) has yielded elevated rates of screening failure for children born preterm or with low birthweight. We extended these findings with a detailed examination of M-CHAT items in a large sample of children born at extremely low gestational age. The sample was grouped according

2011 Paediatric and perinatal epidemiology

15. Autism spectrum disorder

unusual posturing motor stereotypies sensory interests evidence of other neurodevelopmental disorder macrocephaly male sex positive FHx genetic variants karyotype (chromosomal) abnormalities Diagnostic investigations ASD screening tests Childhood Autism Rating Scale (CARS) Modified Checklist for Autism in Toddlers (M-CHAT) Childhood Autism Screening Test (CAST) diagnostic questionnaires (e.g., Autism Diagnostic Interview-Revised [ADI-R]; Developmental, Dimensional, and Diagnostic Interview [3di (...) Autism spectrum disorder Autism spectrum disorder - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Autism spectrum disorder Last reviewed: February 2019 Last updated: March 2018 Summary Children and adults with autism spectrum disorder (ASD) have social communication and interaction difficulties and show restricted, repetitive, and stereotyped patterns of behaviours, interests, or activities. Social communication

2018 BMJ Best Practice

16. Assessment, diagnosis and interventions for autism spectrum disorders

and interventions for autism spectrum disorders 9 Pharmacological interventions for adults New 10 Service provision No new evidence identified 10.4 Support during transition Updated 11 Provision of information 11.2 Checklist for provision of information Minor revision 11.3 Sources of further information Updated 12 Implementing the guideline Completely revised 13 The evidence base New 1.2 REMIT OF THE GUIDELINE 1.2.1 OVERALL OBJECTIVES This guideline provides recommendations based on current evidence for best (...) conditions. 4.1.7 INSTRUMENTS TO AID IDENTIFICATION OF ADULTS WITH ASD A systematic review by NICE identified studies using the Autism Spectrum Quotient-10 (AQ-10), the Autism Screening Questionnaire/Social Communication Questionnaire (ASQ/SCQ), the Autism Behaviour Checklist (ABC) and the Pervasive Developmental Disorder in Mental Retardation Scale (PDD-MRS) for case identification in adults. Most were appraised to be at high risk of bias. 13 No high-quality studies published after the NICE guideline

2016 SIGN

17. Autism in adults: diagnosis and management

supporting the integrated delivery of services across all care settings supporting the smooth transition to adult services for young people going through the pathway auditing and reviewing the performance of the pathway [3] . [1] See Autism spectrum disorder in under 19s: recognition, referral and diagnosis (NICE guideline CG128). [2] Allison C, Auyeung B, Baron-Cohen S (2012) T owards brief 'red flags' for autism screening: the short Autism Spectrum Quotient and the short Quantitative Checklist (...) for Autism in toddlers in 1000 cases and 3000 controls. Journal of the American Academy of Child and Adolescent Psychiatry 51: 202–12. [3] Adapted from Common mental health disorders: identification and pathways to care (NICE guideline CG123). Autism spectrum disorder in adults: diagnosis and management (CG142) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 10 of 501 1 Guidance Guidance The following guidance is based

2012 National Institute for Health and Clinical Excellence - Clinical Guidelines

18. Screening and Diagnostic Tools for Autism Spectrum Disorder in Children: A Review of Guidelines

diagnosis. 5 Recommended ASD screening tools from guidelines that supported their use included the Modified Checklist for Autism in Toddlers (M-CHAT) 3 in patients 16-30 months of age (to be used in conjunction with the follow-up interview to help increase sensitivity), the Screening Tool Screening and Diagnostic Tools for Autism Spectrum Disorder in Children 4 for Autism in Two-Year-Olds (STAT) 3 for children 24-36 months of age, and the Autism Screening Questionnaire (ASQ) 2 in children failing (...) are a useful way to gather information on children with an increased risk of autism in a structured way, however, they are not essential and should not be used to make or rule out a diagnosis of autism. 5 ABC = The Autism Behaviour Checklist; ASD = Autism Spectrum Disorders; ASQ = Autism Screening Questionnaire; CHAT = Checklist for Autism in Toddlers; GARS = Gilliam Autism Rating Scale; KADI = Krug Asperger’s Disorder Index; M-CHAT = Modified Checklist for Autism in Toddlers; NR = not reported; STAT

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

19. Risk Assessment for Parents Who Suspect Their Child Has Autism Spectrum Disorder: Machine Learning Approach. (PubMed)

, using automated text analysis tools and minimal standard questioning.Participants were 115 parents with concerns regarding their child's social-communication development. Children were 16- to 30-months old, and 57.4% (66/115) had a family history of autism spectrum disorder. Parents reported their concerns online, and completed an autism spectrum disorder-specific screener, the Modified Checklist for Autism in Toddlers-Revised, with Follow-up (M-CHAT-R/F), and a broad developmental screener (...) Risk Assessment for Parents Who Suspect Their Child Has Autism Spectrum Disorder: Machine Learning Approach. Parents are likely to seek Web-based communities to verify their suspicions of autism spectrum disorder markers in their child. Automated tools support human decisions in many domains and could therefore potentially support concerned parents.The objective of this study was to test the feasibility of assessing autism spectrum disorder risk in parental concerns from Web-based sources

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2018 Journal of medical Internet research

20. Clinical Features of Children With Autism Who Passed 18-Month Screening. (PubMed)

Clinical Features of Children With Autism Who Passed 18-Month Screening. We compared sex-stratified developmental and temperamental profiles at 18 months in children screening negative for autism spectrum disorder (ASD) on the Modified Checklist for Autism in Toddlers (M-CHAT) but later receiving diagnoses of ASD (false-negative group) versus those without later ASD diagnoses (true-negative group).We included 68 197 screen-negative cases from the Norwegian Mother and Child Cohort Study (49.1

2018 Pediatrics

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