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Modified Apt Test

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1. Modified Apt Test

Modified Apt Test Modified Apt Test Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Modified Apt Test Modified Apt Test Aka: Modified (...) Apt Test II. Indications Assess for in III. Mechanism Differentiates Fetal from Maternal Blood IV. Technique Collect bloody vaginal fluid Add a small amount of tap water (Hemolyzes blood) Centrifuge sample Add 5 cc pink supernatant to 1 cc Hydroxide 1% Read in 2 minutes (may be difficult) Pink sample indicates fetal Yellow-Brown sample indicates adult Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Modified Apt Test." Click

2018 FP Notebook

2. Potassium Hydroxide: An Alternative Reagent to Perform the Modified Apt Test. (PubMed)

Potassium Hydroxide: An Alternative Reagent to Perform the Modified Apt Test. We tested the performance of potassium hydroxide (KOH) in the modified Apt test under different experimental conditions using sodium hydroxide as a positive control. Like sodium hydroxide, KOH differentiated fresh fetal and adult blood stains on a cloth but not dried blood. KOH may be used to perform the Apt test at the bedside. Copyright © 2014 Elsevier Inc. All rights reserved.

2014 Journal of Pediatrics

3. Modified Apt Test

Modified Apt Test Modified Apt Test Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Modified Apt Test Modified Apt Test Aka: Modified (...) Apt Test II. Indications Assess for in III. Mechanism Differentiates Fetal from Maternal Blood IV. Technique Collect bloody vaginal fluid Add a small amount of tap water (Hemolyzes blood) Centrifuge sample Add 5 cc pink supernatant to 1 cc Hydroxide 1% Read in 2 minutes (may be difficult) Pink sample indicates fetal Yellow-Brown sample indicates adult Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Modified Apt Test." Click

2015 FP Notebook

4. Rehabilitation of Attention in Patients With MCI and Brain Subcortical Vascular Changes Using the APT-II

improve patient's overall quality of life because these learned skills are applicable to real-life situations. The main expected results are: 1) an impact of APT-II on disability, everyday cognition, quality of life, and performance on attention tests at short and long term after rehabilitation programme ending as compared with standard care; 2) a reduction of the risk of transition to dementia at 1 year follow-up as compared with control group. Condition or disease Intervention/treatment Phase Mild (...) in activities of daily living and quality of life [ Time Frame: 6 months ] The primary outcome of this study is to improve functionality in activities of daily living and quality of life in patients who undergo a rehabilitation program with the Attention Process Training-II (APT-II) program. Secondary Outcome Measures : Cognitive performance [ Time Frame: 6 months ] Improvement in cognitive performance will be evaluated according to the evidence of a clinically significant increase in scores for tests

2013 Clinical Trials

5. Public health service provision by community pharmacies: a systematic map of evidence

://eppi.ioe.ac.uk/) hold the copyright for the text of their reviews. The EPPI-Centre owns the copyright for all material on the website it has developed, including the contents of the databases, manuals, and keywording and data-extraction systems. The centre and authors give permission for users of the site to display and print the contents of the site for their own non-commercial use, providing that the materials are not modified, copyright and other proprietary notices contained in the materials are retained (...) ; Fajemisin 2013) and might be a person's only point of contact with a healthcare professional (LGA 2013). The range of services provided in community pharmacies are broad and varied, ranging from long- established services such as prescription services and sale of over the counter medicines, to health advice, education, distribution and advice around emergency hormonal contraception (EHC) and condoms and information or testing for specific conditions such as cholesterol testing. Further services

2019 EPPI Centre

6. Replication of psychometric properties of the FSFI and validation of a modified version (FSFI-LL) assessing lifelong sexual function in an unselected sample of females. (PubMed)

require assessment of sexual function over a broader time frame.The purpose of this study was to develop a modified version of the widely used FSFI which allows assessment of women's lifelong sexual function-the FSFI-LL-and to evaluate the psychometric properties and aptness of this new version.A total of 1,589 unselected female twins from the TwinsUK registry completed both original and new versions of the FSFI. After applying exclusion criteria, 1,489 women were eligible for this study.Reliability (...) was tested using Cronbach's alpha coefficient. Construct validity was evaluated by exploratory factor analysis and confirmatory factor analysis (CFA). Domain response differences between the original FSFI and the FSFI-LL were assessed using unpaired t-tests.The modified FSFI-LL showed adequate internal consistency reliabilities for all six dimensions and the total score (Cronbach's α = 0.79 - 0.92). Principal component analysis resulted in a best fitting five-factor solution. CFA confirmed the underlying

2010 Journal Of Sexual Medicine

7. Heart Disease and Stroke Statistics

could be attributed to modifiable risk factors (such as high BP, obesity, hyperglycemia, hyperlipidemia, and renal dysfunction), and 74% could be attributed to behavioral risk factors, such as smoking, sedentary lifestyle, and an unhealthy diet. Globally, 29% of the risk of stroke was attributable to air pollution. Although global age-adjusted mortality rates for ischemic and hemorrhagic stroke decreased between 1990 and 2015, the absolute number of people who have strokes annually, as well

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2019 American Heart Association

8. Professional Practice Guidelines for the Psychological Practice with Boys and Men

role strain and gender role conflict (Pleck, 1981, 1995; O’Neil, 2008; O’Neil & Renzulli, 2013), and negatively influence mental health (e.g., O’Neil, 2008, 2013, 2015) and physical health (Courtenay, 2011; Gough & Robertson, 2017). Indeed, boys and men are overrepresented in a variety of psychological and social problems. For example, boys are dispro- portionately represented among schoolchildren with learning dif- ficulties (e.g., lower standardized test scores) and behavior prob- lems (e.g (...) , & Ferrara, 2017). Providers are encouraged to help clients to develop self-advocacy skills and to tap into their personal and collective resilience in addressing these difficult experiences (dickey, Singh, Chang, & Rehrig, 2017). Men who understand their privilege and power may be less apt to rely on power, control, and violence in their relationships (McDermott, Schwartz, & Trevathan- Minnis, 2012; Schwartz, Magee, Griffin, & Dupuis, 2004). Research suggests that helping men understand the negative con

2019 American Psychological Association

9. A cost-utility analysis of biosimilar infliximab compared to reference infliximab in adult switch patients with Crohn’s disease: A Canadian analysis

and effects of switching to biosimilar infliximab over a five-year time horizon. Clinical inputs were obtained from NOR-SWITCH and other published pivotal trials. Costs were obtained from Canadian sources. A total of 10,000 simulations were run. Sensitivity analysis was used to test the robustness of the results to variations in uncertain parameters. 3 RESULTS: In the reference case, total costs for switching to biosimilar infliximab were $50,191 (standard deviation [SD]: $4,771) and 3.06 (SD: 0.38) QALYs (...) of Canada, 2012). These are a serious complication of CD and these patients must be managed differently from those with luminal CD, on which this analysis will focus. 1.4.4 Diagnosis Phenotypic heterogeneity, variable activity and symptom overlap with other digestive disorders can make the diagnosis of CD challenging (Hanauer, Sandborn, & The Practice Parameters Committee of the American College of Gastroenterology, 2001). There are however several tests that can be conducted to confirm a CD diagnosis

2019 SickKids Reports

10. Management of Stroke Rehabilitation

when clinicians take into account the needs of individual patients, available resources, and limitations unique to an institution or type of practice. Every healthcare professional making use of these guidelines is responsible for evaluating the appropriateness of applying them in the setting of any particular clinical situation. These guidelines are not intended to represent Department of Veterans Affairs or TRICARE policy. Further, inclusion of recommendations for specific testing (...) patients, poor functional outcomes are commonplace. Approximately 44% of individuals aged 18-50 experience moderate disability after stroke, requiring at least some assistance with activities of daily living (ADL) and/or mobility (modified Rankin Scale score >2).[3] Even in patients with so-called “mild” or “improving” stroke, a recent study found that only 28% were discharged to home, 16% required admission to acute rehabilitation facilities, and 11% were admitted to skilled nursing facilities.[4] VA

2019 VA/DoD Clinical Practice Guidelines

11. Management of Osteoporosis in Survivors of Adult Cancers With Nonmetastatic Disease

The literature search of the 2018 systematic review by the US Preventive Services Task Force in the noncancer population was used as the evidentiary base upon which the Expert Panel based many of its recommendations. A total of 61 additional studies on topics and populations not covered in the US Preventive Services Task Force review were also included. Patients with cancer with metastatic disease and cancer survival outcomes related to bone-modifying agents are not included in this guideline (...) . RECOMMENDATIONS Patients with nonmetastatic cancer may be at risk for osteoporotic fractures due to baseline risks or due to the added risks that are associated with their cancer therapy. Clinicians are advised to assess fracture risk using established tools. For those patients with substantial risk of osteoporotic fracture, the clinician should obtain a bone mineral density test. The bone health of all patients may benefit from optimizing nutrition, exercise, and lifestyle. When a pharmacologic agent

2019 American Society of Clinical Oncology Guidelines

12. Guidelines on autopsy practice: Third trimester antepartum and intrapartum stillbirth

of the content of the document represents custom and practice, and is based on the substantial clinical experience of the authors. All evidence included in this guideline has been graded using modified SIGN guidance see Appendix B. No major organisational changes or cost implications have been identified that would hinder the implementation of the guideline. A formal revision cycle for all guidelines takes place on a five-year cycle. The College will ask the authors of the guideline to consider whether (...) are UK consultant and trainee perinatal/paediatric pathologists and general histopathologists with an interest in perinatal pathology. The recommendations will also be of value to pathologists working outside the UK, obstetricians, neonatal paediatricians, anatomical pathology technologists (APTs) and bereavement midwives. 2 The role of the autopsy The role of the autopsy is to: · provide information regarding the baby to the bereaved family establish the immediate cause and timing of intrauterine

2017 Royal College of Pathologists

13. 2017 Focused update on Dual Antiplatelet Therapy (DAPT)

DES for Treatment of Coronary Revascularization INR International normalized ratio ISAR Intracoronary Stenting and Antithrombotic Regimen ISAR-SAFE Intracoronary Stenting and Antithrombotic Regimen: Safety and Efficacy of 6 Months Dual Antiplatelet Therapy After Drug-Eluting Stenting ISAR-TRIPLE Intracoronary Stenting and Antithrombotic Regimen–Testing of a 6-Week Versus a 6-Month Clopidogrel Treatment Regimen in Patients With Concomitant Aspirin and Oral Anticoagulant Therapy Following Drug (...) Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome TRILOGY ACS Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes TRITON-TIMI 38 Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel–Thrombolysis in Myocardial Infarction TROPICAL-ACS Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment For Acute Coronary Syndromes Trial VA Veterans

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2017 European Society of Cardiology

14. Guidelines for the use of hydroxycarbamide in children and adults with sickle cell disease

consent should be confirmed for all patients on hydroxycarbamide, at least at each Annual Review (1D) Stroke prevention Risk factors for acute ischaemic stroke in childhood include abnormal Transcranial Doppler (TCD) velocities, cerebral vasculopathy, silent cerebral infarction, low Hb and low HbF%. By modifying these risk factors, hydroxycarbamide may have a role to play in limiting the risk of childhood stroke. In adults, the risk factors are potentially different and the role of hydroxycarbamide (...) was seen in mean TCD velocity after a mean of 10 months of treatment in children on hydroxycarbamide. This difference did not reach statistical significance in the intention‐to‐treat analysis. Hydroxycarbamide therapy has not been formally tested as first line therapy for children with high risk TCDs but feasibility data suggest reductions in TCD velocity can occur as early as 3 months after starting treatment (Galadanci et al , ). Transfusions have an established role in the primary prevention

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2018 British Committee for Standards in Haematology

15. Guideline for the management of adults with Systemic Lupus Erythematosus

with the main EULAR/ERA-EDTA recommendations for the management of LN Management of SLE patients with renal involvement SOA a Assessment of renal involvement 1. Indications for first renal biopsy in SLE 97 Any sign of renal involvement—in particular, urinary findings such as reproducible proteinuria ≥0.5 g/24 h, especially with glomerular haematuria and/or cellular casts—should be an indication for renal biopsy. Renal biopsy is indispensable since, in most cases, clinical, serologic and laboratory tests (...) for first renal biopsy in SLE 97 Any sign of renal involvement—in particular, urinary findings such as reproducible proteinuria ≥0.5 g/24 h, especially with glomerular haematuria and/or cellular casts—should be an indication for renal biopsy. Renal biopsy is indispensable since, in most cases, clinical, serologic and laboratory tests cannot accurately predict renal biopsy findings. 2. Pathological assessment of kidney biopsy 98 The use of the International Society of Nephrology/Renal Pathology Society

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2017 British Society for Rheumatology

16. Code of practice and performance standards for forensic pathologists dealing with suspicious deaths in Scotland

on the current literature. 2.7 Departure from the standards Where pathologists become aware of an unjustifiable departure from these standards, whether by themselves or by another practitioner, that departure must be brought to the attention of the pathologist’s instructing party. 2.8 Record keeping The maintenance of adequate records is vital and full notes must be kept of briefings and conferences, as well as of all work carried out, tests performed and results obtained. Pathologists’ records should (...) examination and to a radiologist’s opinion in due course. The examination should not normally be conducted without the assistance of skilled mortuary technical staff. The pathologist should brief the anatomical pathology technician (APT) on the nature of the case and their tasks. An experienced APT or similar person can assist with the dissection at the discretion of the pathologist, but must be under the control and supervision of the pathologist at all times. Technical staff may, for instance, open

2016 Royal College of Pathologists

17. Eating disorders: recognition and treatment.

caused by misuse of diabetes medication Diabetes educational interventions, if the person has any gaps in their knowledge For people with suspected hypoglycaemia, test blood glucose: Before all supervised meals and snacks When using the hypoglycaemia treatment algorithm After correction doses For people with suspected hyperglycaemia or hypoglycaemia, and people with normal blood glucose levels who are misusing insulin, healthcare professionals should test for blood ketones: When using (...) and managing overweight and obesity, see the NGC summary of the NICE guideline . Assessment and Monitoring of Physical Health in Anorexia Nervosa GPs should offer a physical and mental health review at least annually to people with anorexia nervosa who are not receiving ongoing treatment for their eating disorder. The review should include: Weight or BMI (adjusted for age if appropriate) Blood pressure Relevant blood tests Any problems with daily functioning Assessment of risk (related to both physical

2017 National Guideline Clearinghouse (partial archive)

19. Probiotics and Prebiotics

—the concept 1.1 History and definitions Over a century ago, Elie Metchnikoff (a Russian scientist, Nobel laureate, and professor at the Pasteur Institute in Paris) postulated that lactic acid bacteria (LAB) offered health benefits capable of promoting longevity. He suggested that “intestinal auto-intoxication” and the resultant aging could be suppressed by modifying the gut microbiota and replacing proteolytic microbes—which produce toxic substances including phenols, indoles, and ammonia from (...) Shirota to battle diarrheal outbreaks. A probiotic product with this strain has been marketed since 1935. These were early predecessors in a scientific field that has blossomed. Today, a search of PubMed for human clinical trials shows that over 1500 trials have been published on probiotics and close to 350 on prebiotics. Although these studies are heterogeneous with regard to strain(s), prebiotics tested, and populations included, accumulated evidence supports the view that benefits are measurable

2017 World Gastroenterology Organisation

20. Diagnosis of Upper Quadrant Lymphedema Secondary to Cancer: Clinical Practice Guideline From the Oncology Section of the American Physical Therapy Association

measurement may be used for assessment but have not been studied as diagnostic tests (Expert Opinion) Trunk or Breast Lymphedema Little research is available to guide diagnosis of truncal or breast lymphedema Ultrasound has the potential to determine tissue changes consistent with different stages of lymphedema - (Expert Opinion) Tissue dielectric constant is an emerging diagnostic tool that may be useful in assisting with assessment of lymphedema (Grade C) Head and Neck Lymphedema Modified Head and Neck (...) and extent of medical interventions. Additionally, variability across the populations studied, length of follow-up, diagnostic criteria and methods, and definitions of lymphedema contribute to inconsistencies in incidence and prevalence statistics. Prior to establishing a plan of care, clinicians obtain a history and perform body function and structure tests and measures to establish a diagnosis, assess the stage and/or severity of the condition, and then determine the impact on activity

2017 American Physical Therapy Association

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