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Modified Apt Test

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1. Modified Apt Test

Modified Apt Test Modified Apt Test Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Modified Apt Test Modified Apt Test Aka: Modified (...) Apt Test II. Indications Assess for in III. Mechanism Differentiates Fetal from Maternal Blood IV. Technique Collect bloody vaginal fluid Add a small amount of tap water (Hemolyzes blood) Centrifuge sample Add 5 cc pink supernatant to 1 cc Hydroxide 1% Read in 2 minutes (may be difficult) Pink sample indicates fetal Yellow-Brown sample indicates adult Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Modified Apt Test." Click

2018 FP Notebook

2. Potassium Hydroxide: An Alternative Reagent to Perform the Modified Apt Test. (PubMed)

Potassium Hydroxide: An Alternative Reagent to Perform the Modified Apt Test. We tested the performance of potassium hydroxide (KOH) in the modified Apt test under different experimental conditions using sodium hydroxide as a positive control. Like sodium hydroxide, KOH differentiated fresh fetal and adult blood stains on a cloth but not dried blood. KOH may be used to perform the Apt test at the bedside. Copyright © 2014 Elsevier Inc. All rights reserved.

2014 Journal of Pediatrics

3. Modified Apt Test

Modified Apt Test Modified Apt Test Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Modified Apt Test Modified Apt Test Aka: Modified (...) Apt Test II. Indications Assess for in III. Mechanism Differentiates Fetal from Maternal Blood IV. Technique Collect bloody vaginal fluid Add a small amount of tap water (Hemolyzes blood) Centrifuge sample Add 5 cc pink supernatant to 1 cc Hydroxide 1% Read in 2 minutes (may be difficult) Pink sample indicates fetal Yellow-Brown sample indicates adult Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Modified Apt Test." Click

2015 FP Notebook

4. Rehabilitation of Attention in Patients With MCI and Brain Subcortical Vascular Changes Using the APT-II

improve patient's overall quality of life because these learned skills are applicable to real-life situations. The main expected results are: 1) an impact of APT-II on disability, everyday cognition, quality of life, and performance on attention tests at short and long term after rehabilitation programme ending as compared with standard care; 2) a reduction of the risk of transition to dementia at 1 year follow-up as compared with control group. Condition or disease Intervention/treatment Phase Mild (...) in activities of daily living and quality of life [ Time Frame: 6 months ] The primary outcome of this study is to improve functionality in activities of daily living and quality of life in patients who undergo a rehabilitation program with the Attention Process Training-II (APT-II) program. Secondary Outcome Measures : Cognitive performance [ Time Frame: 6 months ] Improvement in cognitive performance will be evaluated according to the evidence of a clinically significant increase in scores for tests

2013 Clinical Trials

5. Replication of psychometric properties of the FSFI and validation of a modified version (FSFI-LL) assessing lifelong sexual function in an unselected sample of females. (PubMed)

require assessment of sexual function over a broader time frame.The purpose of this study was to develop a modified version of the widely used FSFI which allows assessment of women's lifelong sexual function-the FSFI-LL-and to evaluate the psychometric properties and aptness of this new version.A total of 1,589 unselected female twins from the TwinsUK registry completed both original and new versions of the FSFI. After applying exclusion criteria, 1,489 women were eligible for this study.Reliability (...) was tested using Cronbach's alpha coefficient. Construct validity was evaluated by exploratory factor analysis and confirmatory factor analysis (CFA). Domain response differences between the original FSFI and the FSFI-LL were assessed using unpaired t-tests.The modified FSFI-LL showed adequate internal consistency reliabilities for all six dimensions and the total score (Cronbach's α = 0.79 - 0.92). Principal component analysis resulted in a best fitting five-factor solution. CFA confirmed the underlying

2010 Journal Of Sexual Medicine

6. Heart Disease and Stroke Statistics

could be attributed to modifiable risk factors (such as high BP, obesity, hyperglycemia, hyperlipidemia, and renal dysfunction), and 74% could be attributed to behavioral risk factors, such as smoking, sedentary lifestyle, and an unhealthy diet. Globally, 29% of the risk of stroke was attributable to air pollution. Although global age-adjusted mortality rates for ischemic and hemorrhagic stroke decreased between 1990 and 2015, the absolute number of people who have strokes annually, as well

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2019 American Heart Association

7. Professional Practice Guidelines for the Psychological Practice with Boys and Men

role strain and gender role conflict (Pleck, 1981, 1995; O’Neil, 2008; O’Neil & Renzulli, 2013), and negatively influence mental health (e.g., O’Neil, 2008, 2013, 2015) and physical health (Courtenay, 2011; Gough & Robertson, 2017). Indeed, boys and men are overrepresented in a variety of psychological and social problems. For example, boys are dispro- portionately represented among schoolchildren with learning dif- ficulties (e.g., lower standardized test scores) and behavior prob- lems (e.g (...) , & Ferrara, 2017). Providers are encouraged to help clients to develop self-advocacy skills and to tap into their personal and collective resilience in addressing these difficult experiences (dickey, Singh, Chang, & Rehrig, 2017). Men who understand their privilege and power may be less apt to rely on power, control, and violence in their relationships (McDermott, Schwartz, & Trevathan- Minnis, 2012; Schwartz, Magee, Griffin, & Dupuis, 2004). Research suggests that helping men understand the negative con

2019 American Psychological Association

8. Guidelines on autopsy practice: Third trimester antepartum and intrapartum stillbirth

of the content of the document represents custom and practice, and is based on the substantial clinical experience of the authors. All evidence included in this guideline has been graded using modified SIGN guidance see Appendix B. No major organisational changes or cost implications have been identified that would hinder the implementation of the guideline. A formal revision cycle for all guidelines takes place on a five-year cycle. The College will ask the authors of the guideline to consider whether (...) are UK consultant and trainee perinatal/paediatric pathologists and general histopathologists with an interest in perinatal pathology. The recommendations will also be of value to pathologists working outside the UK, obstetricians, neonatal paediatricians, anatomical pathology technologists (APTs) and bereavement midwives. 2 The role of the autopsy The role of the autopsy is to: · provide information regarding the baby to the bereaved family establish the immediate cause and timing of intrauterine

2017 Royal College of Pathologists

9. 2017 Focused update on Dual Antiplatelet Therapy (DAPT)

DES for Treatment of Coronary Revascularization INR International normalized ratio ISAR Intracoronary Stenting and Antithrombotic Regimen ISAR-SAFE Intracoronary Stenting and Antithrombotic Regimen: Safety and Efficacy of 6 Months Dual Antiplatelet Therapy After Drug-Eluting Stenting ISAR-TRIPLE Intracoronary Stenting and Antithrombotic Regimen–Testing of a 6-Week Versus a 6-Month Clopidogrel Treatment Regimen in Patients With Concomitant Aspirin and Oral Anticoagulant Therapy Following Drug (...) Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome TRILOGY ACS Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes TRITON-TIMI 38 Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel–Thrombolysis in Myocardial Infarction TROPICAL-ACS Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment For Acute Coronary Syndromes Trial VA Veterans

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2017 European Society of Cardiology

10. Guidelines for the use of hydroxycarbamide in children and adults with sickle cell disease

consent should be confirmed for all patients on hydroxycarbamide, at least at each Annual Review (1D) Stroke prevention Risk factors for acute ischaemic stroke in childhood include abnormal Transcranial Doppler (TCD) velocities, cerebral vasculopathy, silent cerebral infarction, low Hb and low HbF%. By modifying these risk factors, hydroxycarbamide may have a role to play in limiting the risk of childhood stroke. In adults, the risk factors are potentially different and the role of hydroxycarbamide (...) was seen in mean TCD velocity after a mean of 10 months of treatment in children on hydroxycarbamide. This difference did not reach statistical significance in the intention‐to‐treat analysis. Hydroxycarbamide therapy has not been formally tested as first line therapy for children with high risk TCDs but feasibility data suggest reductions in TCD velocity can occur as early as 3 months after starting treatment (Galadanci et al , ). Transfusions have an established role in the primary prevention

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2018 British Committee for Standards in Haematology

11. Guideline for the management of adults with Systemic Lupus Erythematosus

with the main EULAR/ERA-EDTA recommendations for the management of LN Management of SLE patients with renal involvement SOA a Assessment of renal involvement 1. Indications for first renal biopsy in SLE 97 Any sign of renal involvement—in particular, urinary findings such as reproducible proteinuria ≥0.5 g/24 h, especially with glomerular haematuria and/or cellular casts—should be an indication for renal biopsy. Renal biopsy is indispensable since, in most cases, clinical, serologic and laboratory tests (...) for first renal biopsy in SLE 97 Any sign of renal involvement—in particular, urinary findings such as reproducible proteinuria ≥0.5 g/24 h, especially with glomerular haematuria and/or cellular casts—should be an indication for renal biopsy. Renal biopsy is indispensable since, in most cases, clinical, serologic and laboratory tests cannot accurately predict renal biopsy findings. 2. Pathological assessment of kidney biopsy 98 The use of the International Society of Nephrology/Renal Pathology Society

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2017 British Society for Rheumatology

12. Code of practice and performance standards for forensic pathologists dealing with suspicious deaths in Scotland

on the current literature. 2.7 Departure from the standards Where pathologists become aware of an unjustifiable departure from these standards, whether by themselves or by another practitioner, that departure must be brought to the attention of the pathologist’s instructing party. 2.8 Record keeping The maintenance of adequate records is vital and full notes must be kept of briefings and conferences, as well as of all work carried out, tests performed and results obtained. Pathologists’ records should (...) examination and to a radiologist’s opinion in due course. The examination should not normally be conducted without the assistance of skilled mortuary technical staff. The pathologist should brief the anatomical pathology technician (APT) on the nature of the case and their tasks. An experienced APT or similar person can assist with the dissection at the discretion of the pathologist, but must be under the control and supervision of the pathologist at all times. Technical staff may, for instance, open

2016 Royal College of Pathologists

13. Eating disorders: recognition and treatment.

caused by misuse of diabetes medication Diabetes educational interventions, if the person has any gaps in their knowledge For people with suspected hypoglycaemia, test blood glucose: Before all supervised meals and snacks When using the hypoglycaemia treatment algorithm After correction doses For people with suspected hyperglycaemia or hypoglycaemia, and people with normal blood glucose levels who are misusing insulin, healthcare professionals should test for blood ketones: When using (...) and managing overweight and obesity, see the NGC summary of the NICE guideline . Assessment and Monitoring of Physical Health in Anorexia Nervosa GPs should offer a physical and mental health review at least annually to people with anorexia nervosa who are not receiving ongoing treatment for their eating disorder. The review should include: Weight or BMI (adjusted for age if appropriate) Blood pressure Relevant blood tests Any problems with daily functioning Assessment of risk (related to both physical

2017 National Guideline Clearinghouse (partial archive)

15. Probiotics and Prebiotics

—the concept 1.1 History and definitions Over a century ago, Elie Metchnikoff (a Russian scientist, Nobel laureate, and professor at the Pasteur Institute in Paris) postulated that lactic acid bacteria (LAB) offered health benefits capable of promoting longevity. He suggested that “intestinal auto-intoxication” and the resultant aging could be suppressed by modifying the gut microbiota and replacing proteolytic microbes—which produce toxic substances including phenols, indoles, and ammonia from (...) Shirota to battle diarrheal outbreaks. A probiotic product with this strain has been marketed since 1935. These were early predecessors in a scientific field that has blossomed. Today, a search of PubMed for human clinical trials shows that over 1500 trials have been published on probiotics and close to 350 on prebiotics. Although these studies are heterogeneous with regard to strain(s), prebiotics tested, and populations included, accumulated evidence supports the view that benefits are measurable

2017 World Gastroenterology Organisation

16. The Association of Coloproctology of Great Britain and Ireland Consensus Guidelines in Surgery for Inflammatory Bowel Disease

strictureplasty is used for medium‐length strictures (5–20 cm) . For longer strictures, some studies recommended nonconventional methods such as modified Finney, combined Heineke–Mikulicz and Finney, modified Heineke–Mikulicz and Michelassi (side‐to‐side isoperistaltic strictureplasty) - . An international, multicentre, prospective, observational study of the Michelassi technique in 184 patients from six centres proved its safety, with low morbidity, mortality and recurrence rates . Also, a systematic review

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2018 Association of Coloproctology of Great Britain and Ireland

17. 2016 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation

with a C ongestive Heart Failure, H ypertension, A ge, D iabetes, S troke/Transient Ischemic Attack (CHADS 2 ) score ≥ 1; aspirin (acetylsalicylic acid; ASA) for patients < 65 years of age with a CHADS 2 score = 0 with arterial vascular disease (coronary, aortic, or peripheral); and no antithrombotic therapy for patients < 65 years of age with a CHADS 2 score = 0 and no arterial vascular disease. Bleeding risks should be modified whenever possible. A non-vitamin K antagonist oral anticoagulant (NOAC (...) in atrial fibrillation and flutter. Can J Cardiol . 2011 ; 27 : 74–90 | | | | | Using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) standards, individual studies and literature were reviewed for quality and bias; the literature review process is outlined in the evidence tables, which are included in the Supplementary Material and on the CCS Web site. The section on concomitant AF and CAD was developed in collaboration with the CCS Antiplatelet (APT) Guidelines Committee

2016 Canadian Cardiovascular Society

18. Surgical Management of Stones: AUA/Endourology Society Guideline

and Expert Opinions when insufficient evidence existed. Guideline Statements Imaging, Pre-operative Testing 1. Clinicians should obtain a non-contrast CT scan on patients prior to performing PCNL. Strong Recommendation; Evidence Level Grade C 2. Clinicians may obtain a non-contrast CT scan to help select the best candidate for SWL versus URS. Conditional Recommendation; Evidence Level Grade C 3. Clinicians may obtain a functional imaging study (DTPA or MAG‐3) if clinically significant loss of renal (...) to construct the Guideline. Data on study type (e.g., randomized controlled trial [RCT], controlled clinical trial [CCT], observational study), perioperative testing, treatment parameters (e.g., type of treatment), patient characteristics (e.g., age, stone size and location), outcomes (e.g., stone-free rate, residual fragments, quality of life [QoL]) and complications were extracted. Almost all the studies that reported on preoperative testing (99 computed tomography [CT] scan, 10 renal scan, 128 renal

2016 American Urological Association

19. Selection of Optimal Adjuvant Chemotherapy Regimens for Human Epidermal Growth Factor Receptor 2 (HER2) ?Negative and Adjuvant Targeted Therapy for HER2-Positive Breast Cancers

for Women With Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer) are testing the efficacy (and safety) of docetaxel-cyclophosphamide × six cycles versus three-drug anthracycline- and taxane-containing regimens in high-risk HER2-negative, node-negative or node-positive breast cancer. The ASCO Panel modified the CCO recommendation to specify that docetaxel-cyclophosphamide should be administered for four cycles and added the statement to the recommendation that, on the basis (...) oncologists and a methodologist drafted guideline recommendations. These draft recommendations were subsequently circulated to the Early Breast Cancer Systemic Therapy Consensus Panel, which included the working group members and 14 additional medical oncologists from Ontario as part of a modified Delphi consensus development technique for which consensus was defined as 80% agreement and no strong disagreement. By using a 5-point point Likert scale (strongly disagree to strongly agree), Consensus Panel

2016 American Society of Clinical Oncology Guidelines

20. A PACE-gate or an editorial without perspectives?

disagree but he refutes very little of what Dr. Geraghty wrote—and much like the response by White et al, the arguments he does make miss the point. I strongly second Dr. Geraghty’s suggestion to Mental Elf readers to look into this more closely before taking Dr. Brurberg at his word. Anonymous reviewer replied: View There are objective tests e.g. Paul et al 1994, but no one uses them. The fact that it was an unblinded trial is rather irrelevant as you can’t do blinded trials on interventions like CBT (...) to address the central concern, namely that subjective outcomes are inherently biased in unblinded non-pharmacological trials, just as they are in alternative medicine. Repeating claims of efficacy when no objective measures of functioning have been shown (and those that did explicitly measure activity levels or neuropsychological testing showed no change between groups) shows that these people simply don’t care about truth. We as patients are telling you (authors and defenders of these trials

2017 The Mental Elf

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