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8421. Weight Loss Program to Prevent Heart Disease

program promoting weight loss through physical activity and health diet using a mobile health application (app), pedometer to track daily step-counts, and social networking (in-person and virtual social networking through Facebook) to reduce risks for metabolic syndrome in Filipino Americans with type 2 diabetes on metformin. Subjects will be asked: 1) to use a mobile app diary every day to input their weight, and calories (food and drink intake) and 2) wear a pedometer everyday to monitor (...) Americans. Condition or disease Intervention/treatment Phase Insulin Resistance Metabolic Syndrome Type 2 Diabetes Behavioral: PilAm Go4Health Weight-loss Program Behavioral: Active Control Not Applicable Detailed Description: Filipino Americans are the second largest Asian population and fastest growing racial group in the United States. They have one of the highest rates of insulin resistance (type 2 diabetes = T2DM) and central obesity (fat distributions primarily in the abdominal region). T2DM

2014 Clinical Trials

8422. Effectiveness of Two Silicone Dressings for Sacral and Heel Pressure Ulcer Prevention

/limited mobility in bed), 4A (= care depended, limited mobility in bed), 4B (= totally immobile) according to the Jones classification modified by Charité Expected minimum length of stay at least three days Informed consent (or by legal representative) Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study (...) provided by (Responsible Party): PD Dr. Jan Kottner, Charite University, Berlin, Germany Study Details Study Description Go to Brief Summary: The aim of this randomized controlled trial is to test the efficacy of preventive dressings for pressure ulcer prevention. Condition or disease Intervention/treatment Phase Pressure Ulcer Device: Mepilex® Border Sacrum and Mepilex® Border Heel Not Applicable Detailed Description: Patients of intensive acute care and residents of institutional long-term care

2014 Clinical Trials

8423. Functional Later Rehabilitation in Older Adults: Effectiveness of Physical Exercises

will be mobility-related disability and participants will be assessed in the baseline, at the end of the intervention (3 months), at 6 and 12 months. The participants will receive monthly phone calls to investigate falls and exercise adherence. Adverse effects will be monitored. Condition or disease Intervention/treatment Phase Hip Fractures Other: Home-based physical exercise intervention Other: Control Group Usual Care Not Applicable Detailed Description: Over a lifetime, about half of women and a quarter (...) 20, 2014 Last Update Posted : November 28, 2017 See Sponsor: Universidade Cidade de Sao Paulo Information provided by (Responsible Party): Monica Rodrigues Perracini, Universidade Cidade de Sao Paulo Study Details Study Description Go to Brief Summary: Hip fractures resulting from falls increase substantially with advancing age and less than a half of the elderly that have sustained and survived after the surgery regain their former levels of mobility. There is increasing evidence

2014 Clinical Trials

8424. Trial to Compare Femoral Nerve Block With Local Anaesthetic Injection for Post-operative Pain After Knee Replacement.

Procedure: Sedation or general anaesthesia Drug: Pre-medication Drug: Intra-operative medication Drug: Post-operative analgesia - morphine Drug: Post-operative analgesia - ibuprofen and paracetamol Drug: Regular anti emetics Not Applicable Detailed Description: Knee pain and stiffness is a common problem which can sometimes be improved by inserting a replacement knee joint. An anaesthetist is a doctor who specialises in looking after patients undergoing surgery, and there are a variety of different (...) [ Time Frame: Pre op and 6 weeks post operatively ] EQ-5D-5L (EuroQol 5 dimensions score) will be used to measure the satisfaction the patient has with their knee in the fields of mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more

2014 Clinical Trials

8425. Exploring the Use of Non-invasive Neuromodulation Combined With Exercise in People With Advanced Multiple Sclerosis (MS)

-invasive neuromodulation (CN-NINM). The activation of these structures induces neuroplasticity when combined with specific physical exercises, can reduce symptoms of advanced MS, targeting primarily postural stability (sitting and standing), upper extremity movement, and ability to perform self-transfers. Condition or disease Intervention/treatment Phase Multiple Sclerosis Device: Neuromodulation Rehabilitation Not Applicable Detailed Description: The intervention will be similar to that used (...) : March 2014 Actual Primary Completion Date : January 2017 Actual Study Completion Date : June 28, 2017 Resource links provided by the National Library of Medicine related topics: related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Neuromodulation Rehabilitation Balance, posture and gait activities; therapeutic exercise for isolated muscle control; transfer training; and relaxation training using neurostimulation modulation. 2-week in lab intervention training

2014 Clinical Trials

8426. Effects of Manual Therapy and Exercise in the Treatment of Ankle Sprains

or disease Intervention/treatment Phase Ankle Sprains Procedure: Experimental (proprioception exercises, muscle strengthening, joint mobilization) Procedure: Control (proprioception exercises, muscle strengthening) Not Applicable Detailed Description: The recurrent ankle sprain means the most frequent complication from the ankle sprain and the previous phase of the chronic ankle stability (CAI), which involves between 20 - 41% of all ankle sprains. Residual pain concerns the first symptom after (...) 2014 Actual Primary Completion Date : April 2014 Actual Study Completion Date : July 2014 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Experimental performed the same exercises and manual therapy during 4 weeks Procedure: Experimental (proprioception exercises, muscle strengthening, joint mobilization) The experimental group performed a combined protocol of proprioception (the patient doing

2014 Clinical Trials

8427. Hispanic Secondary Stroke Prevention Initiative

. The project examines the effectiveness of a combined multilevel intervention consisting of Community Health Workers (CHW) and mobile based phone technologies in lowering of systolic blood pressure (SBP) which is the most important risk factor for recurrent stroke. Condition or disease Intervention/treatment Phase Stroke Behavioral: Community Health Worker (CHW) Other: usual care and health education brochures every 4 months. Not Applicable Study Design Go to Layout table for study information Study Type (...) by (Responsible Party): Olveen Carrasquillo, University of Miami Study Details Study Description Go to Brief Summary: Stroke is a leading cause of death and functional impairments and stroke risk factors (SRFs) disproportionately affect Latino populations. In the Hispanic Secondary Stroke Prevention Initiative (HISSPI) the investigators propose a study using Community Health Workers (CHW) and mobile technologies using cell phones to reduce the risk for a recurrent stroke among Latino stroke patients

2014 Clinical Trials

8428. In-vivo Comparison of Different Levels of Femoral Rollback in a Primary Total Knee Arthroplasty

or is it reduced by, for example, remodelling of the posterior cruciate ligament? Condition or disease Intervention/treatment Phase Gonarthrosis Device: ATTUNE® Knee System Device: PFC® SIGMA® Knee System Not Applicable Detailed Description: Postoperative knee pain is one of the most challenging problems following total knee arthroplasty. Of all the possible complications, the patella-femoral joint is an important cause of postoperative knee pain and prosthetic failure. Nägerl et al. observed that the tibia (...) Primary Completion Date : April 2015 Estimated Study Completion Date : September 2015 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: test group 1 Retrospective test group 1 (n=10, ATTUNE® Knee System, rotating platform, cruciate retaining) with intraoperative high level rollback Device: ATTUNE® Knee System Experimental: test group 2 Retrospective test group 2 (n=10, ATTUNE® Knee System, rotating platform

2014 Clinical Trials

8429. An Evaluation of the Spectra Optia CMNC Collection Procedure

Intervention/treatment Phase Healthy Apheresis Donors Mononuclear (MNC) Cell Donors Device: Spectra Optia CMNC Device: COBE Spectra MNC Drug: Granulocyte-colony stimulating factor (G-CSF) Not Applicable Detailed Description: This is a prospective, randomized, cross-over, multi-center study to evaluate the performance of the Spectra Optia system's CMNC Collection Procedure, compared to the COBE Spectra system's MNC Procedure in mobilized healthy donors. Up to 60 subject may be consented to meet (...) sickle cell trait or disease History of use in the past week or anticipated need for lithium Concurrent enrollment in another clinical study that could impact the results or participation in this study Active infection or any serious underlying medical condition that contraindicates apheresis Women who are pregnant or lactating Known history of significant head trauma Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may

2014 Clinical Trials

8430. Arousal Pathways and Emergence From Sedation

Information provided by (Responsible Party): michal roll, Tel-Aviv Sourasky Medical Center Study Details Study Description Go to Brief Summary: Emergence from sedation involves an increase in both the level of consciousness and arousal. Some insight to the neural core of consciousness was gained in the recent past. Our research objective is to characterize for the first time the spatiotemporal mobilization of the ascending reticular activating system during emergence from sedation; stated otherwise (...) Criteria: Healthy males (ASA scale 1-2), volunteers only Exclusion Criteria: Use of chronic medications or illicit drugs Metallic implants Previous brain injury General anaesthesia up to a week earlier to research examination Known drug sensitivity to Propofol, soybean oil or peanuts Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor

2014 Clinical Trials

8431. NMES During the Day and Prior to Sleep

validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02253329 Recruitment Status : Completed First Posted : October 1, 2014 Last Update Posted : May 21, 2015 Sponsor: Maastricht University Medical Center Information provided by (Responsible Party): Maastricht University Medical Center Study Details Study Description Go to Brief (...) Summary: In the present study, the effect of a bolus of intrinsically labeled milk directly after one-legged NMES (Neuromuscular Electrical Stimulation) will be studied under two conditions: during the day and prior to sleep Condition or disease Intervention/treatment Phase Sarcopenia Procedure: Dietary protein plus NMES during the day Procedure: Dietary protein plus NMES prior to sleep Not Applicable Detailed Description: In the present study, the effect of a bolus of intrinsically labeled milk

2014 Clinical Trials

8432. Home-based Balance Training Using Wii Fit After Stroke: A Feasibility Study

: HBE Wii (EG) Other: HBE Control (CG) Phase 1 Phase 2 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 14 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Supportive Care Official Title: The Application of a Video-game System (Nintendo Wii®) as an Independent Exercise Program to Improve Mobility After Stroke - a Randomized Phase II Trial Study Start Date (...) Information provided by (Responsible Party): André Golla, Martin-Luther-Universität Halle-Wittenberg Study Details Study Description Go to Brief Summary: BACKGROUND: Virtual gaming systems offer new possibilities for home-based exercises (HBE) in rehabilitation. Pilot studies with stroke patients indicate that the application of Nintendo Wii® (WII) is practicable and can improve balance under clinical conditions. However, larger trials are necessary to verify these positive effects after discharge from

2014 Clinical Trials

8433. Development of Workplace Physical Activity Promotion Models in Taiwan

Intervention/treatment Phase Occupational Health Behavioral: Workplace intervention Not Applicable Detailed Description: Several evidences have shown that regular physical activity could benefit not only to a healthy lifestyle, but also reduce mortality rate. However, the number of people who perform regular physical activity are still in a low proportion of world population. In Taiwan, people are mostly inactive and have low level of physical activity at their workplaces. Therefore, developing a healthy (...) type B: Workers tend to be standing during work hours. Likewise, two different enterprises will respectively stand for the experiment group and the control group. The intervention plan is to implement a cyclic or iterative process recommended by WHO. The process includes eight steps: (1) Mobilize; (2) Assemble; (3) Assess; (4) Prioritize; (5) Plan; (6) Do; (7) Evaluate; (8) Improve. By gaining the commitment from the highest authority in the enterprise and communicated to all workers

2014 Clinical Trials

8434. LATCH: Lactation Advice Thru Texting Can Help

gestation Have an unlimited text message cell phone plan Knows how to send a text message 5th grade literacy level Exclusion Criteria: Lack of fluency in either English or Spanish Infant born premature (<37 weeks) > 3 days in NICU Any major maternal-newborn medical problem affecting breastfeeding Birth weight <5lbs Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact (...) Breastfeeding Support Behavioral: LATCH Intervention Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 249 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Health Services Research Official Title: LATCH: Lactation Advice Thru Texting Can Help Actual Study Start Date : August 2014 Actual Primary Completion Date : February 2016 Actual Study Completion Date : February 2016

2014 Clinical Trials

8435. The Electrophysiological Investigation of Higher Level Neural Manifestations of Freezing of Gait in Parkinson's Disease Patient

. severe mood disorders such as major depression. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02214251 Locations Layout table for location information Taiwan China Medical University Hospital/Neuro Depart Taichung, Taiwan, 40447 Sponsors (...) : Completed First Posted : August 12, 2014 Last Update Posted : July 28, 2016 Sponsor: China Medical University Hospital Collaborator: National Science Council, Taiwan Information provided by (Responsible Party): Chon-Haw Tsai, China Medical University Hospital Study Details Study Description Go to Brief Summary: We aim to investigate the higher level mechanism of gait disorders in PD patients by ambulatory recording of electroencephalographic (EEG) and leg electromyographic (EMG) signals during

2014 Clinical Trials

8436. Effectiveness of Cervicothoracic Manipulative Treatment in Unilateral Shoulder Impingement Syndrome: A Randomized Controlled Trial.

subjects will be randomly assigned to one of two groups. Intervention: For 5-weeks, the groups 1 will undergo tratment comprising manipulative protocol techniques for the cervicothoracic spine (2/week) and the group 2 will develop a home exercise (2/week). Main Outcome Measures: Intensity of pain, disability, and range of motion data will be collected at baseline, and 24hr after the last therapy application. Mixed-model analyses of variance will be used to examine the effects of the treatment on each (...) outcome measure. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 92 participants Allocation: Randomized Intervention Model: Single Group Assignment Masking: Single (Participant) Primary Purpose: Treatment Study Start Date : August 2014 Actual Primary Completion Date : May 2015 Actual Study Completion Date : December 2015 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm

2014 Clinical Trials

8437. eStimCycle: Early Rehabilitation in Critical Care

process on ICU admission Lower limb amputation/s Unable to perform study physical outcome measures pre morbidly due to condition impairing mobility Assessed by medical staff as not-expected to survive ICU Pregnancy BMI > 40 Presence of external fixator or superficial metal in lower limb Open wounds or skin abrasions at electrode application points Presence of cardiac or diaphragmatic pacemaker or implanted defibrillator with no underlying rhythm, as confirmed by the treating physician Transferred from (...) Other Name: Cycle ergometer (RT300 supine model Restorative Therapies, Ltd or Letto 300.), six channel SAGE stimulator and two RT50 wireless stimulator channels. Other: Standard Care standard care physiotherapy including respiratory and rehabilitation with mobilisation activities such as sitting out of bed, marching on the spot, and mobility training. Active Comparator: Standard Care Both groups will receive usual medical and nursing care in the ICU and ward. Both groups (control and intervention

2014 Clinical Trials

8438. Efficacy Study of Assiut Femoral Compression Device Versus Manual Compression in the Achievement of Hemostasis

as easy application of the device with good fixation and stability and achieving final hemostasis. Device Stability was defined as absence of tilt and/or mobility after application of the device on top of the patient groin. Assessment of the device application was performed using a questionnaire with a scale of three grades; "Easy", "Difficult" and "Requires Improvement". Assessment of stability and fixation of the device was performed on a scale defined as "Very Good", "Good" and "Bad". Procedure (...) on discharge [ Time Frame: 24 post procedure ] major adverse event (MAE) was defined as symptomatic bleeding associated with hemoglobin drop ≥5 g/dL requiring blood transfusion, fatal bleeding that directly results in death, a pseudoaneurysm or arteriovenous fistula, distal arterial embolism, infections requiring administration of IV antibiotics or debridement, and the need for vascular surgery. Secondary Outcome Measures : Device success: [ Time Frame: 5 minutes during application ] This was defined

2014 Clinical Trials

8439. The Predictive Factors of Good Clinical Response to Cholinesterase Inhibitors in Alzheimer Disease and Mixed Dementia

Title: The Predictive Factors of Good Clinical Response to Cholinesterase Inhibitors in Mild and Moderate Alzheimer Disease and Mixed Dementia: a Naturalistic Study Study Start Date : June 2009 Actual Primary Completion Date : March 2013 Actual Study Completion Date : March 2013 Resource links provided by the National Library of Medicine related topics: related topics: resources: Groups and Cohorts Go to Group/Cohort Intervention/treatment Alzheimer disease or mixed dementia Patients were evaluated (...) four times. In the first consultation, without taking cholinesterase inhibitors (ChEI), after three, six and 12 months taking ChEI. Drug: cholinesterase inhibitors The first group received donepezil (5 or 10 mg) the second group received galantamine (16 or 24 mg) The third group received rivastigmine (3 or 4,5 or 6 mg BID) according to the treating physician. Other Name: No applicable Outcome Measures Go to Primary Outcome Measures : Cognitive results [ Time Frame: Patients were evaluated from 06

2014 Clinical Trials

8440. Peripheral Nerve Block (Femoral

effects the time required for patient mobilisation. Condition or disease Intervention/treatment Phase Arthroscopic ACL Rerpair Surgery Anesthesia Care Other: Ultrasound Guided Femoral Sciatic Obturator nerve blocks Other: General Anesthesia femoral bolus Other: General anesthesia femoral continuous Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 150 participants Allocation: Randomized Intervention Model: Parallel (...) Outcome Measures Go to Primary Outcome Measures : Surgery completed without pain for the patient [ Time Frame: Completion of the surgery ] Use of VAS score Postoperative pain [ Time Frame: 1st postoperative day ] Use of VAS score Secondary Outcome Measures : Mobilization of the knee [ Time Frame: 24 weeks postoperatively ] How many degrees can the patient bend the knee Other Outcome Measures: Chronic pain development [ Time Frame: 24 weeks postoperatively ] Use of questionnaire for the functional

2014 Clinical Trials

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