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8401. Rest Easy: Is Bed Rest Really Necessary After Surgical Repair of an Ankle Fracture?

the confidence to endorse a change to current clinical practice. Condition or disease Intervention/treatment Phase Ankle Injuries Fracture Procedure: Early mobilization Procedure: Standard mobilization Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 104 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Care Provider) Primary Purpose: Treatment Official Title: Randomized Controlled (...) such as blood clots in the lungs or leg veins, or chest infections such as pneumonia. Prolonged bed rest is also known to cause weakness and a loss of fitness such that recovery may be slower. In this research the investigators will be randomly allocating patients to mobilize within 24 hours post operatively or to rest in bed for 48 hours with their leg well elevated. The investigators will measure length of stay and wound healing and integrity at 14 days. This study aims to investigate whether getting

2008 Clinical Trials

8402. Teledermatology: an update. (PubMed)

as for the diagnosis and management of equivocal pigmented skin lesions. The feasibility of mobile teledermatology and mobile teledermoscopy recently has been proven, and these new facilities have the potential to become an easy applicable tool for everyone and may open the door for a new flexible triage system for detection of skin cancer in general and melanoma in particular. The implementation of virtual slide systems for teledermatopathology has allowed avoiding the limitations imposed by conventional (...) microphotography. Finally, web consultations in dermatology are a rather new tool that became available in the last years and teledermatologic services through the Internet offer many possibilities, including continuing medical education, on-line atlases and databases, and specific web application suited for teledermatology (ie, www.telederm.org).

2008 Seminars in Cutaneous Medicine and Surgery

8403. Educational and Research Implications of Portable Human Patient Simulation in Acute Care Medicine. (PubMed)

) simulation and introduce new approaches to acute care education and research. Portable simulation is already conducted across multiple specialties and disciplines. In situ medical simulations are those carried out within actual clinical environments, while off-site portable simulations take place outside of clinical practice settings. Mobile simulation systems feature functionality while moving between locations; progressive simulations are longer-duration events using mobile simulations that follow (...) Educational and Research Implications of Portable Human Patient Simulation in Acute Care Medicine. Advanced medical simulation has become widespread. One development, the adaptation of simulation techniques and manikin technologies for portable operation, is starting to impact the training of personnel in acute care fields such as emergency medicine (EM) and trauma surgery. Unencumbered by cables and wires, portable simulation programs mitigate several limitations of traditional (nonportable

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2008 Academic Emergency Medicine

8404. Survey of information technology in Intensive Care Units in Ontario, Canada. (PubMed)

electronically, the availability of decision support tools, the availability of electronic imaging systems for radiology, the use of electronic order entry and medication administration systems, and the availability of hardware and wireless or mobile systems. We used Fisher's Exact tests to compare IT availability and Classification and Regression Trees (CART) to estimate the optimal cut-point for the number of computers per ICU bed.We obtained responses from 50 hospitals (68.5% of institutions with level 3 (...) and 8 different PACS systems were in use. Half of the respondents described the number of computers available as insufficient. Wireless networks and mobile computing systems were used in 23 ICUs (46%).Ontario ICUs demontrate a high prevalence of the use of basic information technology systems. However, implementation of the more complex and potentially more beneficial applications is low. The wide variation in vendors utilized may impair information exchange, interoperability and uniform data

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2008 Medical Informatics and Decision Making

8405. NTX Wireless Patient Monitoring System

of the NTX wireless monitoring system alerts Evaluate patient compliance with wearing device Determine false alarm rates Condition or disease Intervention/treatment Desaturation Bradycardia Tachycardia Hypertension Hypotension Other: Rapid Response Team Detailed Description: Approximately 150 patients will have wireless monitors attached to their arm. They will have their vital signs filtered through software that generates alerts and records data. The alert engine will produce pager and application (...) : January 2009 Actual Study Completion Date : June 2009 Groups and Cohorts Go to Group/Cohort Intervention/treatment monitored patients hospitalized for longer than 24 hours and are located on the 4th, 5th, and 6th floors of the Vanderbilt University Medical Center Round Wing Other: Rapid Response Team If the subject is experiencing a life threatening change in their vital signs, the Rapid Response Team will be initiated per VUMC protocol. Other Name: - attending nurse action per VUMC protocol Outcome

2008 Clinical Trials

8406. Comparison of Lymph Drainage and Connective Tissue Massage in Fibromyalgia Patients

: Hacettepe University Abant Izzet Baysal University Information provided by: Pamukkale University Study Details Study Description Go to Brief Summary: The present study was designed to analyze and compare the effects of Manual Lymph Drainage Therapy and Connective Tissue Massage in females with Fibromyalgia (FM). Condition or disease Intervention/treatment Phase Fibromyalgia Other: Manual Lymph Drainage Therapy and Connective Tissue Massage Not Applicable Detailed Description: The lack of specific (...) of pain. Two major subcategories exist that divide these techniques into those which produce joint motion and those which do not. The first subcategory includes manipulation, mobilization, and manual traction. The second subcategory involves both generalized soft tissue therapies, such as the many types of massage, and focal soft tissue therapy (10). Consequently, there is currently no recognized effective treatment for FM patients. In addition, there is limited number of study dealing with the effect

2008 Clinical Trials

8407. Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity

13, 2008 Last Update Posted : March 13, 2008 Sponsor: University of South Alabama Information provided by: University of South Alabama Study Details Study Description Go to Brief Summary: The purpose of this study is to test whether ACULAR, a nonsteroidal anti-inflammatory eye drop medication, can prevent the development of retinopathy of prematurity (ROP) and/ or decrease its severity.In this study ACULAR will be compared to a placebo (artificial tear). The hypothesis would be that ACULAR (...) to be effective in preventing the post cataract surgery inflammation that result in macular edema in adults. Activation of the prostaglandin cascade has been demonstrated in animal models of ROP. A previous non randomized study using ACULAR for ROP prevention has shown a possible beneficial effect and no observed adverse effect. To clearly demonstrated and confirm this finding a randomized study is thus necessary before one can advocate its use for prevention of ROP.The medication is FDA approved

2008 Clinical Trials

8408. Exercise and Pioglitazone for HIV-Metabolic Syndromes

adiposity more than pioglitazone alone. These improvements should translate into reduced cardiovascular disease risk in HIV-infected people. Condition or disease Intervention/treatment Phase HIV Infections Type 2 Diabetes Obesity HIV AIDS Cardiovascular Disease Lipodystrophy Drug: Pioglitazone Behavioral: Exercise training Not Applicable Detailed Description: Our prior research has examined the pathogenesis and potential treatments for metabolic complications in people living with HIV. We have adopted (...) the "lipotoxicity" hypothesis for Metabolic Syndrome X to explain the pathogenesis of impaired glucose tolerance (IGT) and fat redistribution in HIV: increased lipolysis and mobilization of lipids and free fatty acids from subcutaneous adipose depots leads to their excessive deposition in muscle and liver which contributes to dyslipidemia, insulin resistance, increased hepatic glucose output, and possibly visceral fat accumulation. Effective treatments have not been identified. Consensus groups recommend

2008 Clinical Trials

8409. Strength Training and Medication Effects in Parkinson Disease Effects on Hypokinesia in Parkinson Disease

replacement medication Exclusion Criteria: previous surgical management of PD (pallidotomy, DBS) motor fluctuations and or dyskinesias uncontrolled by medications. central nervous system disorder (e.g., other than Parkinson's disease) myopathic disease (e.g., focal myopathy) that affects skeletal muscle structure/function rheumatological disease that has an effect on muscle and/or mobility unstable cardiovascular disease that limits exercise abilities impaired knee flexion, <90 degrees, extreme (...) Strength Training and Medication Effects in Parkinson Disease Effects on Hypokinesia in Parkinson Disease Strength Training and Medication Effects in Parkinson Disease Effects on Hypokinesia in Parkinson Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2008 Clinical Trials

8410. A New Clinical Pathway for Patients With Fractured Neck of Femur

Aged Procedure: geriatric work-up Procedure: Orthopedic care as usual Not Applicable Detailed Description: The intention of the present project is to evaluate the effectiveness of multi-factorial medical treatment of patients with hip fractures in a specially designed geriatric unit for elderly hip fracture patients (orthogeriatric unit) as compared to traditional care in an orthopedic unit. Every year 9000 patients undergo surgery for hip fractures in Norway. The epidemic of hip fractures is among (...) Central Norway Regional Health Authority Information provided by (Responsible Party): Norwegian University of Science and Technology Study Details Study Description Go to Brief Summary: The intention is to evaluate the effectiveness of a multi-factorial medical treatment of patients with hip fractures in a specially designed unit for elderly hip fracture patients (orthogeriatric unit) as compared to traditional care in an orthopedic unit. Condition or disease Intervention/treatment Phase Hip Fracture

2008 Clinical Trials

8411. Mobility Assessment of Patients With Total Hip Arthroplasty

Mobility Assessment of Patients With Total Hip Arthroplasty Mobility Assessment of Patients With Total Hip Arthroplasty - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Mobility Assessment of Patients (...) Osteoarthritis Arthroplasty Hip Replacement Procedure: Motion analysis Not Applicable Detailed Description: Much research has shown that patients are generally satisfied with pain relief in the months and years following a total hip replacement (THR) or hip resurfacing procedure. However, many express dissatisfaction with their ability to perform daily activities, a reduced walking ability and long-term lower extremity muscle weakness. Given the general lack of knowledge surrounding joint motion of the lower

2008 Clinical Trials

8412. Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses

to the incidence of postoperative anastomotic leakage, anastomotic stricture and time to ileostomy closure, if applicable. Condition or disease Intervention/treatment Phase Rectal Cancer Ulcerative Colitis Familial Adenomatous Polyposis Diverticulitis Device: GORE SEAMGUARD® Bioabsorbable Staple Line Reinforcement Procedure: Staple line without reinforcement Not Applicable Detailed Description: This is a randomized prospective trial that compares the use of GORE SEAMGUARD® Bioabsorbable Staple Line (...) ClinicalTrials.gov identifier (NCT number): NCT00663819 Locations Layout table for location information United States, Alabama University of South Alabama Mobile, Alabama, United States, 36617 United States, California University of Southern California, Keck School of Medicine Los Angeles, California, United States, 90033 United States, Florida University of South Florida-Cleveland Clinic Florida Weston, Florida, United States, 33331 United States, Illinois Advocate Healthcare/Good Shepard Hospital Barrington

2008 Clinical Trials

8413. Impact of Prolonged Physical Therapy on Gait Performance of Chronic Phase Stroke Patients

Outcome Measures : the average number of steps per day recorded over 3 days in an outpatient setting [ Time Frame: day 3 and then 6 months later ] Secondary Outcome Measures : the scores to the scales (the 6 minutes walking test, the Wade's test, the Rivermead Mobility Index Score, the Barthel Index Score) [ Time Frame: day 0 and then day 55 ] for the medico-economic study, the direct medical and non-medical costs associated with physical therapy of chronic stroke patients [ Time Frame: 6 months (...) Not Applicable Detailed Description: The aim of this multi-center, randomized controlled study is to acquire and compare information on gait performance in patients with chronic hemiplegia (six months to two years post-stroke) who either continue to attend two physical therapy sessions per week for two months or who stop physical therapy sessions for two months. This will permit us 1) to assess the efficacy of continuing physical therapy sessions during the chronic phase of post-stroke hemiplegia, 2

2008 Clinical Trials

8414. A Study of Yoga for Treating Geriatric Insomnia

and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00661843 Recruitment Status : Completed First Posted : April 18, 2008 Last Update Posted : October 5, 2010 Sponsor: Shaare Zedek Medical Center Collaborators: KTH Royal Institute of Technology The Australia-Israel Scientific Exchange Foundation (AISEF) Israel Yoga Teachers (...) Association Information provided by: Shaare Zedek Medical Center Study Details Study Description Go to Brief Summary: Insomnia is common in the elderly population and is associated with increased health problems, reduced quality of life and greater use of sleep inducing drugs. This research aims to examine the effectiveness of Yoga practice to treat insomnia in elderly people, determine the ability to enhance their quality of life and determine if it is suitable to western culture and conditions

2008 Clinical Trials

8415. Clinical Efficacy of 10% Arginine Bicarbonate Prophylaxis Paste

Go to Arm Intervention/treatment Active Comparator: ProClude Prophylaxis paste-A Arginine Bicarbonate prophylaxis paste Device: Arginine/Calcium Carbonate One time treatment Placebo Comparator: Nupro-M Prophylaxis paste -B Control prophylaxis paste (Fluoride free - placebo) Device: Nupro - Fluoride Free Brush twice daily Outcome Measures Go to Primary Outcome Measures : Hypersensitivity to Touch (Tactile) [ Time Frame: Immediately after product application ] Units on a scale: Measured (...) with an electronic force sensing probe (Yeaple Probe): 10, 20, 30, 40, up to 50 grams of force are applied to hypersensitive tooth until pain elicited. Grams of force needed to elicit pain are recorded as hypersensitivity score for the tooth. The higher the score, the higher the hypersensitivity. Air Blast [ Time Frame: Immediately after product application ] Units on a scale using Schiff Cold Air Sensitivity Scale. Response to a constant (duration, pressure, temperature, distance from target) jet of air applied

2008 Clinical Trials

8416. Use of Subtle Vibration to Improve Walking Ability by Lower Limb Amputees

prosthetic socket with mechanical vibrators (stochastic resonance) Device: Conventional prosthetic socket (current clinical practice) Not Applicable Detailed Description: One of the many complications of diabetes is the loss of sensation in the feet. This sensory deficit can negatively impact the postural stability and mobility of non-amputees, since without feedback, it is simply more difficult to stand and walk. For lower limb amputees, the problem is compounded. These patients often have difficulty (...) improved postural stability and locomotor function for these patients. The intervention is based on a phenomenon known as stochastic resonance, whereby the application of sub-threshold vibration enables mechano-receptors previously unable to respond to stimuli to become more susceptible to depolarization. For Veterans with neuropathic proprioceptive losses, stochastic resonance may facilitate a functional response from subtle stimuli where gross inputs were formerly required. Study Design Go to Layout

2008 Clinical Trials

8417. Mini Allo Stem Cell Transplantation for the Treatment of Solid Tumors

Cell Transplantation for the Treatment of Solid Tumors (MiniSolid) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00997529 Recruitment Status : Completed First Posted : October 19, 2009 Last Update Posted : July 18, 2016 Sponsor: Beth Israel Deaconess Medical Center Collaborator: Amgen Information (...) provided by (Responsible Party): David McDermott, Beth Israel Deaconess Medical Center Study Details Study Description Go to Brief Summary: A major focus of recent research has been the development of effective ways of sensitizing the patient's immune system to recognize the cancer as foreign. Allogeneic stem cell transplantation represents a novel way of potentially achieving this goal. There is recent evidence that non-myeloablative allogeneic stem cell transplantation provides effective therapy

2008 Clinical Trials

8418. Evaluation of Long-term Effect of Resonator Therapy on Parkinson's Disease (PD)

participants Official Title: An Open-label Extension Study for Subjects Previously Treated Either in Pilot I or Pilot II Studies of the Application of Magnetic Fields Using the Resonator for the Treatment of Parkinson's Disease. Study Start Date : April 2008 Actual Primary Completion Date : April 2011 Actual Study Completion Date : April 2011 Resource links provided by the National Library of Medicine related topics: related topics: Groups and Cohorts Go to Group/Cohort Intervention/treatment Active (...) for patients with Parkinson's Disease (PD) that evaluates the 8 dimensions of mobility, activities of daily living, emotional well-being, stigma, social support, cognition, and communication. The PDQ-39 Single Index (SI) score is the weighted addition of scores on all 8 dimension and ranges from 0 (no disease impact) to 100 (severe disease impact). Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk

2008 Clinical Trials

8419. pressure sores

pressure sores pressure sores - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search pressure sores Pressure sores may develop rapidly in patients at risk. Once established, they are very difficult to treat so that preventive measures are of utmost importance. pressure ulcers are caused when an area of skin and the tissues below are damaged as a result of being placed under pressure sufficient to impair its blood supply (...) . Typically they occur in a person confined to bed or a chair by an illness and as a result they are sometimes referred to as 'bedsores', or 'pressure sores' pressure ulcers are more likely to occur in people who are seriously ill, have a neurological condition, impaired mobility, impaired nutrition, or poor posture or a deformity also, the use of equipment such as seating or beds which are not specifically designed to provide pressure relief, can cause pressure ulcers Pressure ulcers are to be expected

2010 GP Notebook

8420. bed sores

bed sores bed sores - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search bed sores Pressure sores may develop rapidly in patients at risk. Once established, they are very difficult to treat so that preventive measures are of utmost importance. pressure ulcers are caused when an area of skin and the tissues below are damaged as a result of being placed under pressure sufficient to impair its blood supply. Typically they occur (...) in a person confined to bed or a chair by an illness and as a result they are sometimes referred to as 'bedsores', or 'pressure sores' pressure ulcers are more likely to occur in people who are seriously ill, have a neurological condition, impaired mobility, impaired nutrition, or poor posture or a deformity also, the use of equipment such as seating or beds which are not specifically designed to provide pressure relief, can cause pressure ulcers Pressure ulcers are to be expected if erythema appears

2010 GP Notebook

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