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8341. Effects of Exercise on Cognitive Performance of Patients With Alzheimer-type Dementia. Pilot Study.

intensity aerobic exercise+strength Not Applicable Detailed Description: OBJECTIVE: To evaluate an intervention that combines high intensity aerobic exercise with strength (AAAD) on general cognitive performance of patients affected by mild Alzheimer's disease (AD). DESIGN: Randomized clinical trial in two parallel groups: SCOPE: 2 health center of Basque Health Service , in coordination with its reference neurology services. PARTICIPANTS: 80 patients with mild AD. INTERVENTION: Both groups receiving (...) : Global cognitive performance (Neuropsychological battery TBR-B),neuropsychiatric symptoms (NPI), ADL (Blessed),functional capacity (Test of 6-minute walk), cardiorespiratory Test, muscular strength (hand dynamometer and trunk); PREDICTORS AND CONFOUNDING VARIABLES: baseline cognitive performance, previous physical activity, medication, age, sex, APOE, schooling and cognitive reserve. ANALYSIS: We compared the two groups in terms of observed mean changes from baseline in ADAS measurement and other

2014 Clinical Trials

8342. Use of a Mechanically Passive Rehabilitation Device in Vietnam: Impact on Upper Extremity Hemiparesis After Stroke

to evaluate how stoke impacted the subject's health and life and takes 20-minutes to complete. A Vietnamese translated hard copy will be provided to the participants. A proxy version will be available in Vietnamese, in order for a caregiver or medical personnel to read the test to participants if they were unable to read or write. This survey consists of questions about physical problems, memory, mood, activities of daily living, and mobility during a 4-week timeframe (Vellone, 2014). A licensing (...) with severe to moderate stroke, but that is also simple and does not rely on powered actuators. The hypothesis is that individuals with a severe chronic stroke, who exercise with a mechanically passive rehabilitation device, will have improved arm movement ability without experiencing an increase in arm pain. Condition or disease Intervention/treatment Phase Cerebrovascular Accident Device: Resonating Arm Exerciser Not Applicable Detailed Description: A randomized control trial design will compare two

2014 Clinical Trials

8343. Pressure Sensing to Reduce the Risk of Pressure Ulcer Formation

of a pressure sensing device with continuous visual feedback of pressure imaging may potentially decrease the interface pressure of patients who are at risk of pressure ulcers in an acute hospital setting. Condition or disease Intervention/treatment Phase Pressure Ulcer Device: ForeSite PT™ system Not Applicable Detailed Description: Background: Pressure ulcers result in substantial financial costs to the healthcare system as well as significant distress to affected patients and their families. As interface (...) : Prevention Official Title: Effectiveness of a Pressure-sensing System to Reduce the Risk of Pressure Ulcer Formation by Lowering Interface Pressure in Vulnerable Patient Populations: A Parallel-two-group Randomized Controlled Trial Study Start Date : December 2014 Estimated Primary Completion Date : March 2018 Estimated Study Completion Date : March 2018 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental

2014 Clinical Trials

8344. Functional Intimate Apparel for Adolescents With Early Scoliosis

. Condition or disease Intervention/treatment Phase Scoliosis Device: Functional Intimate Apparel Not Applicable Detailed Description: This project aims to combine clinical experience with textiles and materials sciences to research and develop a functional intimate apparel for adolescents with early scoliosis. As a result, this will reduce the future likelihood of brace wear or surgery. The design of functional intimate apparel will incorporate different mechanisms, such as a) compression and pulling (...) intimate apparel which is called FIA group while one group receives observation only, which is called control group. Masking: Single (Participant) Primary Purpose: Treatment Official Title: Safety and Efficacy of Functional Intimate Apparel for Adolescents With Early Scoliosis Actual Study Start Date : July 15, 2017 Estimated Primary Completion Date : December 31, 2019 Estimated Study Completion Date : December 31, 2020 Resource links provided by the National Library of Medicine related topics: Arms

2014 Clinical Trials

8345. Thol'Impilo: Bringing People Into Care

Eligible for Study: All Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: aged 18 years and older, diagnosed HIV positive at enrolling mobile HCT units, no prior self-reported registration at a health care facility for HIV care, provide consent for participation Exclusion Criteria: self-reported prior or current registration as an HIV patient at a healthcare facility Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your (...) of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02271074 Recruitment Status : Completed First Posted : October 22, 2014 Last Update Posted : July 20, 2016 Sponsor: The Aurum Institute NPC Collaborators: United States Agency for International Development (USAID) Johns Hopkins University London School of Hygiene and Tropical Medicine University

2014 Clinical Trials

8346. Decreasing Over Screening and Treatment of Cervical Precancers in Young Women

Cancer Screening Guidelines for Young Women Actual Study Start Date : July 24, 2014 Estimated Primary Completion Date : December 30, 2017 Estimated Study Completion Date : December 30, 2017 Resource links provided by the National Library of Medicine related topics: resources: Arms and Interventions Go to Arm Intervention/treatment Experimental: Mobile Application (APP) Mobile phone application for providers. Device: Mobile Application (APP) Mobile phone application to maneuver clinicians through (...) years. Condition or disease Intervention/treatment Phase Cervical Cancer Device: Mobile Application (APP) Device: Patient-Centered Approach (PCA) + APP Not Applicable Detailed Description: In this study, we compare two different intervention arms that are designed to prevent over screening and over treatment by increasing adherence to the new US cervical cancer screening guidelines and the American Society for Colposcopy and Cervical Pathology (ASCCP) guidelines for the management of abnormal

2014 Clinical Trials

8347. Brief Intervention for Suicide Risk Reduction in High Risk Adolescents

: ASAP Behavioral: Brite Brite is a HIPAA-compliant mobile application designed to provide the participants with emotion regulation and distress tolerance skills, social support, and convenient access to safety plan resources via the patients' phone. Active Comparator: Treatment as Usual Participants in this grouping were studied as they proceed from inpatient to outpatient care, per usual treatment protocols at each site. Participants completed paper safety plans as part of their regular treatment (...) Southwestern Medical Center Information provided by (Responsible Party): David Brent, University of Pittsburgh Study Details Study Description Go to Brief Summary: Adolescent suicide is the 2nd leading cause of death in this age group. There are no validated treatments to decrease the risk of adolescent suicidal behavior, and there are especially no interventions to target the highest risk period for adolescent suicide and suicidal behavior, namely during the time of transition from inpatient to outpatient

2014 Clinical Trials

8348. SmartScope vs Standard Colposcope for the Evaluation of Cervical Dysplasia

OCT M3 scope Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 30 participants Allocation: Randomized Intervention Model: Single Group Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Diagnostic Official Title: Image Comparison of a Mobile Colposcope (SmartScope) vs. a Standard Colposcope for Directing Cervical Biopsies in Women With Abnormal Pap Smears: A Non-inferiority Trial. Study Start Date (...) : November 2014 Estimated Primary Completion Date : September 2015 Estimated Study Completion Date : September 2015 Resource links provided by the National Library of Medicine resources: Arms and Interventions Go to Arm Intervention/treatment No Intervention: mobile colposcope Device: Mobile OCT M3 scope Outcome Measures Go to Primary Outcome Measures : image non-inferiority [ Time Frame: 6 months ] imafge non-inferiority Eligibility Criteria Go to Information from the National Library of Medicine

2014 Clinical Trials

8349. Short Message Service in Colonoscopy Preparation (PERICLES-II-SMS)

Universität München Study Details Study Description Go to Brief Summary: The purpose of this study is to analyze if integration of new media (SMS) could improve the quality of colonoscopy preparation. Condition or disease Intervention/treatment Phase Colon Cancer Procedure: Colonoscopy Device: mobile phone Not Applicable Detailed Description: The study approach is the implementation of new media into colonoscopy preparation. As most of our patients already use mobile phones the study should evaluate (...) and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: over 18 years old written informed consent mobile phone user appointment for outpatient colonoscopy Exclusion Criteria: no outpatient colonoscopy no mobile phone Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor

2014 Clinical Trials

8350. A Randomized Controlled Trial of Hip Dislocation Techniques for Pediatric Patients With Cerebral Palsy

by instander (hours/ week) Medical Costs [ Time Frame: 4 years (end of study) ] analyze claims data (approx 4 years) Operative Outcomes [ Time Frame: intra-operative ] radiation, total time during surgery, skin dose, blood loss, surgeon experience, hip resection technique Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study (...) pain interference), function (mobility questions), complications and surgical parameters such as OR time and fluoroscopy time. A cost-effectiveness analysis will follow completion of the randomized controlled trial (RCT). The authors hypothesize that mean CPCHILD scores (measured at 1 year) will be significantly higher following the Subtrochanteric Valgus Osteotomy technique compared to Proximal Femoral Resection-Interposition Arthroplasty technique. Furthermore, the Proximal Femoral Resection

2014 Clinical Trials

8351. Pilot Psychoeducational Intervention Model to Improve Nutritional Status in Low Resource Settings

or disease Intervention/treatment Phase Child Malnutrition Child Overnutrition Malnutrition in Children Malnutrition, Child Nutrition Disorders, Child Malnutrition Behavioral: Psychoeducational intervention Not Applicable Detailed Description: Mexico's malnutrition problem goes beyond lack of food. Nutrition transition in our country has modified dietary patterns in a way that now we observe more and more a decrease in consumption of micronutrient rich foods, like vegetables, and an increase (...) Resource Population in the City of Saltillo, Coahuila Mexico. Study Start Date : June 2014 Actual Primary Completion Date : July 2015 Actual Study Completion Date : December 2015 Arms and Interventions Go to Arm Intervention/treatment Experimental: Psychoeducational intervention Participants will be receiving a cooking lesson in their community every 2 weeks for 1 year. Behavioral: Psychoeducational intervention A mobile kitchen visits the 5 selected communities every 2 weeks for a period of 1 year

2014 Clinical Trials

8352. Effectiveness of Online Systematic Brief Psychodynamic Psychotherapy for Neurotic Disorders: Randomized Controlled Trial

of the adaptative diagnosis evolution between groups. Primary Outcomes: The subjects treated with online brief systematic psychodynamic psychotherapy will present an increase in their adaptative efficacy measured by systematic adaptative diagnosis scale (SADS) in comparison to the waiting list group, when contrasting their initial and final adaptative diagnostics. Condition or disease Intervention/treatment Phase Neurotic Disorders Behavioral: Online Systematic Brief Psychodynamic Psychotherapy Not Applicable (...) in Systematic Adaptive Diagnosis Scale (SADS) [ Time Frame: Each participant will be followed, an expected average of 3 months. ] Participants of interventional group will be followed for the duration of therapeutic process, an expected average of 3 months. Participants of control group will be followed after waiting-list period, an expected average of 3 months. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision

2014 Clinical Trials

8353. HIFU in Patients With Non-malignant Thyroid Nodules

Details Study Description Go to Brief Summary: Use of a high intensity focused ultrasound (HIFU) in patients with non-malignant thyroid nodules. Condition or disease Intervention/treatment Phase Non-malignant Thyroid Nodules Device: Echopulse Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 4 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title (...) : Use of a High Intensity Focused Ultrasound (HIFU) in Patients With Non-malignant Thyroid Nodules. Actual Study Start Date : July 2014 Actual Primary Completion Date : October 13, 2015 Actual Study Completion Date : October 13, 2015 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Single arm Device: Echopulse Outcome Measures Go to Primary Outcome Measures : Evaluation of thyroid nodule's volume changes

2014 Clinical Trials

8354. Pilot for The Breast Cancer Endocrine Therapy Adherence (BETA) Trial

years for various reasons, and non-adherence may reduce survival. The current protocol is a pilot study in women with hormone receptor positive breast cancer who are beginning adjuvant endocrine therapy, the purpose of which is to assess the feasibility of a two-way text messaging application, with goals for a larger randomized control study to assess if the application will increase adherence and therefore improve disease free survival. This application includes daily text message medication (...) ) Trial: Efficacy of a Text-messaging Application in Increasing Adherence With Adjuvant Endocrine Therapy for Stage I-III Hormone Receptor Positive Breast Cancer Study Start Date : October 2014 Actual Primary Completion Date : January 2016 Actual Study Completion Date : August 2016 Resource links provided by the National Library of Medicine related topics: related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Text Message Application Intervention The study intervention

2014 Clinical Trials

8355. Long-Term Integrated Telerehabilitation of COPD Patients. A Multi-Center Trial

uncapable to perform the study procedures Presence of comorbidities wich might prevent the patient from safely undertake an exercise program at home Home environment not suitable for installation and use of rehabilitation and monitoring equipment (e.g. physical space, Wi-FI Internet or mobile Internet via 4G) Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information (...) Behavioral: Telemonitoring and education/self-management Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 120 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Supportive Care Official Title: Long-Term Integrated Telerehabilitation of COPD Patients. A Multi-Center Randomized Controlled Trial Actual Study Start Date : October 2014 Estimated

2014 Clinical Trials

8356. Postnatal Smoking Relapse, Its Associated Risk Factors, and a Proactive Sustainable Preventive Intervention

Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: Willingness and ability to participate in the study Married or living with a stable partner Mobile phone Willing to provide mobile phone contact for their husband or partner Exclusion Criteria: Age<18 (minor age in Romania) Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor (...) . The primary hypothesis is that the intervention will increase mothers' smoking abstinence rates. Condition or disease Intervention/treatment Phase Cigarette Smoking Behavioral: Smoking abstinence counseling Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 397 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose

2014 Clinical Trials

8357. Implementation of Comprehensive Stroke Rehabilitation Therapy for Enhanced Quality of Life

, Sub-Acute Other: Standard of Care, Chronic Not Applicable Detailed Description: This comprehensive intervention targets the impairments preventing recovery to normal and safe gait, mobility, function, and life role participation (quality of life). It has been tested in chronic stroke survivors and found efficacious. The QualPro protocol will include three phases, all of which contain components previously mentioned. The QualPro protocol includes implementation of gait coordination training (...) (Clinical Trial) Actual Enrollment : 12 participants Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Implementation of Gait Coordination, Mobility, and Fitness Training for Enhanced Quality of Life and Participation in Life Roles Study Start Date : July 2015 Actual Primary Completion Date : December 27, 2018 Actual Study Completion Date : December 27, 2018 Resource links provided by the National Library of Medicine

2014 Clinical Trials

8358. Pilot Study of Stem Cell Transplantation for Children and Young Adults With Refractory Crohn's Disease.

stem cell transplantation (HSCT) has been of value in other auto-immune diseases and it is possible that it could be of value in CD. This is a pilot study to determine if HSCT is safe and effective for children and young adults with severe CD. For this study the stem cells will come from the patient. This is called an autologous transplant. The patient will undergo collection and storage of his/her peripheral blood stem cells (PBSC). The patient will be given drugs to move (or mobilize) the stem (...) cells from his/her bone marrow into his/her blood where they will be collected on a machine called apheresis (similar to dialysis.) The cells will be stored and given back to the patient about 1 month after collection. Condition or disease Intervention/treatment Phase Crohn's Disease Other: Hematopoietic stem cell transplantation Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 0 participants Intervention Model

2014 Clinical Trials

8359. Electronic Algorithms Based on Host Biomarkers Point of Care Tests to Decide on Admission and Antibiotic Prescription in Tanzanian Febrile Children

mortality due to delayed admission, At the same time, it will decrease irrational use of antibiotics, and hence drug pressure and emergence of drug resistance, which represents one of the most important public health threat our world is facing today. This project has the potential of huge applicability since it is specifically designed for end-users with limited medical skills and low resources, as it is the case in most areas of developing countries. Condition or disease Intervention/treatment Phase (...) Acute Febrile Illness Other: Management of febrile children using e-POCT Other: Management of febrile children using ALMANACH Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 3192 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Diagnostic Official Title: Electronic Algorithms Based on Host Biomarkers Point of Care Tests to Decide on Admission

2014 Clinical Trials

8360. Music Therapy to Restore Motor Deficits After Stroke

to conventional treatment. We also expect to observe improvements in cognitive functions, mood and quality of life. Besides, we hypothesize that these amelioration in motor and cognitive domains will be accompanied by neuroplastic changes in the sensorimotor cortex and corticospinal tract. Condition or disease Intervention/treatment Phase Stroke Paresis Behavioral: Music-supported Therapy Behavioral: home-based Music-supported Therapy Behavioral: Conventional treatment Not Applicable Study Design Go to Layout (...) table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 120 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Official Title: The Application of Music Therapy in the Neurorehabilitation of Motor Deficits After Subacute Stroke Study Start Date : November 2013 Estimated Primary Completion Date : May 2017 Estimated Study Completion Date : July 2017 Arms and Interventions Go

2014 Clinical Trials

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