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Midbrain

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3161. Facilitation of the arterial baroreflex by the ventrolateral part of the midbrain periaqueductal grey matter in rats. Full Text available with Trip Pro

Facilitation of the arterial baroreflex by the ventrolateral part of the midbrain periaqueductal grey matter in rats. 1. The effects of stimulation of the ventrolateral part of the midbrain periaqueductal grey matter (PAG) on the arterial baroreflex were investigated in urethane-chloralose anaesthetized and artificially ventilated rats. 2. Both electrical and chemical stimulation of the ventrolateral PAG provoked hypotension, vagal bradycardia and marked facilitation of baroreflex vagal

1994 The Journal of physiology

3162. Midbrain locked-in state with oculomotor subnucleus lesion. Full Text available with Trip Pro

Midbrain locked-in state with oculomotor subnucleus lesion. 4045492 1985 11 12 2018 11 13 0022-3050 48 9 1985 Sep Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry Midbrain locked-in state with oculomotor subnucleus lesion. 952-3 Uematsu D D Suematsu M M Fukuuchi Y Y Ebihara S S Gotoh F F eng Case Reports Letter England J Neurol Neurosurg Psychiatry 2985191R 0022-3050 IM Brain Diseases diagnosis Humans Male Mesencephalon Middle Aged Quadriplegia diagnosis 1985

1985 Journal of neurology, neurosurgery, and psychiatry

3163. Unilateral left paramedian infarction of thalamus and midbrain: a clinico-pathological study. Full Text available with Trip Pro

Unilateral left paramedian infarction of thalamus and midbrain: a clinico-pathological study. In a patient with a unilateral embolic infarct in the left posterior thalamo-subthalamic paramedian artery territory, neuropathological studies showed involvement of the intralaminar, dorsomedial, and internal part of the ventral posterior nuclei of the thalamus, of the rostral part of the mesencephalic reticular formation, and of the posterior commissure. The patient showed upgaze palsy for voluntary

1986 Journal of neurology, neurosurgery, and psychiatry

3164. A case of Gilles de la Tourette's syndrome with midbrain involvement. Full Text available with Trip Pro

A case of Gilles de la Tourette's syndrome with midbrain involvement. In a 27-year-old patient with Gilles de la Tourette's syndrome a pineal tumor had been found 10 years previously and was apparently a coincidental finding. Minute calcifications were later detected around the third ventricle and the mesencephalic periaqueductal gray matter by high resolution computed tomography. It is argued that this observation may support Devinsky's speculations that midbrain involvement has pathological

1985 Journal of neurology, neurosurgery, and psychiatry

3165. Experience-dependent corticofugal adjustment of midbrain frequency map in bat auditory system Full Text available with Trip Pro

Experience-dependent corticofugal adjustment of midbrain frequency map in bat auditory system Recent studies of corticofugal modulation of auditory information processing indicate that cortical neurons mediate both a highly focused positive feedback to subcortical neurons "matched" in tuning to a particular acoustic parameter and a widespread lateral inhibition to "unmatched" subcortical neurons. This cortical function for the adjustment and improvement of subcortical information processing

1998 Proceedings of the National Academy of Sciences of the United States of America

3166. Activation of midbrain presumed dopaminergic neurones by muscarinic cholinergic receptors: an in vivo electrophysiological study in the rat Full Text available with Trip Pro

Activation of midbrain presumed dopaminergic neurones by muscarinic cholinergic receptors: an in vivo electrophysiological study in the rat 1. Extracellular single-unit recording and iontophoresis were used to examine the effects of different cholinoceptor agonists and antagonists on the firing rate and firing pattern of A9 and A10 presumed dopaminergic neurones in the anaesthetized rat. 2. Administration of low currents (1-5 nA) of the selective muscarinic agonists oxotremorine M (Oxo M (...) to influence the activity of the midbrain dopamine system greatly and may play a role in, and/or be a therapeutic target for, brain disorders in which dopamine is involved (e.g., Parkinson's disease, drug addiction and schizophrenia).

1998 British journal of pharmacology

3167. Lateral gaze synkinesis on downward saccade attempts with paramedian thalamic and midbrain infarct Full Text available with Trip Pro

Lateral gaze synkinesis on downward saccade attempts with paramedian thalamic and midbrain infarct 10577040 1999 11 19 2017 11 14 0022-3050 67 5 1999 Nov Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry Lateral gaze synkinesis on downward saccade attempts with paramedian thalamic and midbrain infarct. 696-7 Versino M M Simonetti F F Egitto M G MG Ceroni M M Cosi V V Beltrami G G eng Case Reports Letter England J Neurol Neurosurg Psychiatry 2985191R 0022-3050

1999 Journal of neurology, neurosurgery, and psychiatry

3168. Electrical stimulation of the midbrain increases heart rate and arterial blood pressure in awake humans Full Text available with Trip Pro

Electrical stimulation of the midbrain increases heart rate and arterial blood pressure in awake humans Electrical stimulation of the hypothalamus, basal ganglia or pedunculopontine nucleus in decorticate animals results in locomotion and a cardiorespiratory response resembling that seen during exercise. This has led to the hypothesis that parallel activation of cardiorespiratory and locomotor systems from the midbrain could form part of the 'central command' mechanism of exercise. However (...) of any site did not affect cardiovascular variables or movement. Electrical stimulation of the midbrain in awake humans can cause a modest increase in cardiovascular variables that is not dependent on movement feedback from exercising muscles. The relationship between this type of response and that occurring during actual exercise is unclear, but it indicates that subcortical command could be involved in 'parallel activation' of the locomotor and cardiovascular systems and thus contribute

2002 The Journal of physiology

3169. Corticofugal modulation of duration-tuned neurons in the midbrain auditory nucleus in bats Full Text available with Trip Pro

Corticofugal modulation of duration-tuned neurons in the midbrain auditory nucleus in bats Animal sounds, as well as human speech sounds, are characterized by multiple parameters such as frequency, intensity, duration, etc. The central auditory system produces neurons tuned to particular durations and frequencies of sounds emitted by a species. In bats, "duration-tuned" neurons are mostly sensitive to short durations and high frequencies of sounds used for echolocation. They are scattered

2001 Proceedings of the National Academy of Sciences of the United States of America

3170. Representation of Waveform Periodicity in the Auditory Midbrain of the Bullfrog, Rana catesbeiana Full Text available with Trip Pro

Representation of Waveform Periodicity in the Auditory Midbrain of the Bullfrog, Rana catesbeiana The period of complex signals is encoded in the bullfrog's eighth nerve by a synchrony code based on phase-locked responding. We examined how these arrays of phase-locked activity are represented in different subnuclei of the auditory midbrain, the torus semicircularis (TS). Recording sites in different areas of the TS differ in their ability to synchronize to the envelope of complex stimuli

2000 JARO: Journal of the Association for Research in Otolaryngology

3171. Modulation of the dinucleotide receptor present in rat midbrain synaptosomes by adenosine and ATP Full Text available with Trip Pro

Modulation of the dinucleotide receptor present in rat midbrain synaptosomes by adenosine and ATP Diadenosine polyphosphates activate dinucleotide receptors in rat midbrain synaptic terminals. The agonist with highest affinity at this receptor, diadenosine pentaphosphate (Ap(5)A), elicits Ca(2+) transients at concentrations ranging from 10(-7) to 10(-3) M with a single-phase curve and an EC(50) value of 56.21+/-1.82 microM. Treatment of synaptosomal preparations with alkaline phosphatase (AP

2000 British journal of pharmacology

3172. Respiratory-associated rhythmic firing of midbrain neurones in cats: relation to level of respiratory drive. Full Text available with Trip Pro

Respiratory-associated rhythmic firing of midbrain neurones in cats: relation to level of respiratory drive. 1. We recorded phrenic nerve activities and single unit firing of mesencephalic neurones in unanaesthetized supracollicularly decerebrated, paralysed and ventilated cats, in which vagi and carotid sinus nerves had been ablated. We made these measurements first at low levels of respiratory drive associated with normal PCO2 levels, then with increased respiratory drive and levels (...) and the independent ventilator-associated rhythm. 6. We interpret our findings to show that the respiratory-associated rhythmic firing of midbrain neurones is not primarily involved in generation or modulation of the motor function of the respiratory oscillator. We believe, instead, that these neurones are part of a sensory pathway conveying information about the magnitude of central neural respiratory drive, as well as spinally transmitted information from receptors in the chest wall, to thalamus and cortex. We

1991 The Journal of physiology

3173. Pure sensory stroke due to midbrain haemorrhage. Full Text available with Trip Pro

Pure sensory stroke due to midbrain haemorrhage. 1955892 1991 12 31 2018 11 13 0022-3050 54 9 1991 Sep Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry Pure sensory stroke due to midbrain haemorrhage. 843 Alvarez-Sabin J J Montalbán J J Tintoré M M Codina A A eng Case Reports Comment Letter England J Neurol Neurosurg Psychiatry 2985191R 0022-3050 IM J Neurol Neurosurg Psychiatry. 1989 Dec;52(12):1427-8 2614441 Adult Brain Neoplasms complications diagnosis

1991 Journal of neurology, neurosurgery, and psychiatry

3174. On the inhibitory actions of baclofen and gamma-aminobutyric acid in rat ventral midbrain culture. Full Text available with Trip Pro

On the inhibitory actions of baclofen and gamma-aminobutyric acid in rat ventral midbrain culture. 1. Whole-cell voltage-clamp recordings were used to study the effects of (-)-baclofen and of gamma-aminobutyric acid (GABA) on neurones cultured from the ventral midbrain of embryonic rats. 2. Baclofen induced an outward current (IBac) at a holding potential of -60 mV. The maximal current was 80 pA, and half-maximal current was evoked by 5 microM-baclofen. The proportion of cells affected (...) by baclofen. The effectiveness of baclofen was greater on cells that had been longer in culture. 8. It is concluded that activation of GABAB receptors has two main effects on neurones cultured from rat ventral midbrain. These are potassium conductance increase, and inhibition of the spontaneous release of GABA and excitatory amino acids; both effects can be observed in tetrodotoxin and cadmium.

1992 The Journal of physiology

3175. Midbrain tegmental lesions affecting or sparing the pupillary fibres. Full Text available with Trip Pro

Midbrain tegmental lesions affecting or sparing the pupillary fibres. Two patients with oculomotor palsy caused by midbrain infarction are reported. In the first, pupillary reaction was affected and in the second this reaction was spared. Because the lesions in the anterior part of the tegmentum were in the upper midbrain in the first patient and in the lower midbrain in the second, it is suggested that the pupillary components of the oculomotor nerve are located in the upper midbrain.

1996 Journal of neurology, neurosurgery, and psychiatry

3176. Antagonism of the effects of (+)-PD 128907 on midbrain dopamine neurones in rat brain slices by a selective D2 receptor antagonist L-741,626. Full Text available with Trip Pro

Antagonism of the effects of (+)-PD 128907 on midbrain dopamine neurones in rat brain slices by a selective D2 receptor antagonist L-741,626. 1. The ability of PD 128907 to activate dopamine receptors in the ventral tegmental area, substantia nigra pars compacta, and striatum was investigated by use of in vitro electrophysiological recording and fast cyclic voltammetry. The affinity of a novel D2 selective antagonist L-741,626 for receptors activated by this agonist was measured to determine (...) = 5). The affinity of L-741,626 for these nerve terminal autoreceptors (pKB = 7.71 +/- 0.06; = 20 nM) was identical to that observed on midbrain dopamine neurones. 6. These data demonstrate that the D3 receptor ligand (+)-PD 128907 is a potent agonist on rat midbrain dopamine neurones. However, its lack of regional selectivity, and the high affinity of the selective D2 receptor antagonist L-741,626 for receptors activated by (+)-PD 128907, was more consistent with an action on D2 autoreceptors

1996 British journal of pharmacology

3177. Expanding cerebral cysts (lacunae): a treatable cause of progressive midbrain syndrome Full Text available with Trip Pro

Expanding cerebral cysts (lacunae): a treatable cause of progressive midbrain syndrome 12588943 2003 04 03 2017 11 14 0022-3050 74 3 2003 Mar Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry Expanding cerebral cysts (lacunae): a treatable cause of progressive midbrain syndrome. 393-4 Longatti P L PL Fiorindi A A Carteri A A Caroli F F Martinuzzi A A eng Case Reports Letter England J Neurol Neurosurg Psychiatry 2985191R 0022-3050 IM Adult Brain Diseases

2003 Journal of neurology, neurosurgery, and psychiatry

3178. Accumulation of Acid-Fast Lipochrome Bodies in Glial Cells of the Midbrain Nigral Lesion in Parkinson’s Disease Full Text available with Trip Pro

Accumulation of Acid-Fast Lipochrome Bodies in Glial Cells of the Midbrain Nigral Lesion in Parkinson’s Disease To confirm or refute the proposed link between nocardiae and Parkinson's disease (PD), we investigated the presence of acid-fast spherical structures similar to filterable nocardiae at the midbrain nigral lesions of three patients with PD. Many clusters of acid-fast lipochrome bodies were dense around blood vessels in the two patients with Hoehn and Yahr stage II and III PD

1998 Clinical and Diagnostic Laboratory Immunology

3179. Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons. Full Text available with Trip Pro

Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons. ATP-sensitive potassium (K-ATP) channels couple the metabolic state to cellular excitability in various tissues. Several isoforms of the K-ATP channel subunits, the sulfonylurea receptor (SUR) and inwardly rectifying K channel (Kir6.X), have been cloned, but the molecular composition and functional diversity of native neuronal K-ATP channels remain unresolved. We

1999 The EMBO journal

3180. Corticofugal modulation of amplitude domain processing in the midbrain of the big brown bat, Eptesicus fuscus. (Abstract)

Corticofugal modulation of amplitude domain processing in the midbrain of the big brown bat, Eptesicus fuscus. Recent studies have shown that the corticofugal system systematically modulates and improves subcortical signal processing in the frequency, time and spatial domains. The present study examined corticofugal modulation of amplitude sensitivity of 113 corticofugally inhibited neurons in the central nucleus of the inferior colliculus (IC) of the big brown bat, Eptesicus fuscus. Cortical

2003 Hearing Research

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