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Microscopic Hematuria Causes in Adults

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1. Asymptomatic Microscopic Hematuria in Women

with asymptomatic hematuria. World J Urol 2008;26:3–7. [ ] Yamagata K, Yamagata Y, Kobayashi M, Koyama A. A long-term follow-up study of asymptomatic hematuria and/or proteinuria in adults. Clin Nephrol 1996;45:281–8. [ ] Yamamoto M, Hibi H, Miyake K. Etiology of asymptomatic microscopic hematuria in adults. Hinyokika Kiyo 1993;39:413–7. [ ] Yasumasu T, Koikawa Y, Uozumi J, Ueda T, Kumazawa J. Clinical study of asymptomatic microscopic haematuria. Int Urol Nephrol 1994;26:1–6 [ ] Hiatt RA, Ordonez JD. Dipstick (...) a diagnosis of asymptomatic microscopic hematuria ( , ). The 2012 American Urological Association guidelines on the evaluation and diagnosis of asymptomatic microscopic hematuria require only a single positive properly collected specimen with three or more red blood cells per high-power field with no obvious benign cause ( ). Additionally, those guidelines have lowered the age threshold for evaluation from older than 40 years to 35 years. The recommended evaluation for all patients meeting the criteria

2017 American College of Obstetricians and Gynecologists

2. Microscopic Hematuria Causes in Adults

Microscopic Hematuria Causes in Adults Microscopic Hematuria Causes in Adults Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Microscopic Hematuria Causes in Adults Microscopic Hematuria Causes in Adults Aka: Microscopic Hematuria Causes in Adults , Adult Microscopic Hematuria Causes From Related Chapters II. Background Consider non-urine source (e.g. vagina or ) III. Causes: Most common of adult Hematuria by history Age Under age 40 years Genitourinary infection Over age 40 years Urinary tract cancer (up to 10% of cases) Prostatic Disease with pain Renal Vein Thrombosis Renal Artery with Hemorrhagic cystitis ( ) Prostatic

2018 FP Notebook

3. Letermovir (Prevymis) - to prevent illness caused by cytomegalovirus (CMV) in adults having an allogeneic haematopoietic stem cell transplant

Letermovir (Prevymis) - to prevent illness caused by cytomegalovirus (CMV) in adults having an allogeneic haematopoietic stem cell transplant 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5520 Send a question via our website www.ema.europa.eu/contact © European Medicines Agency, 2018. Reproduction is authorised provided the source is acknowledged. 9 November 2017 EMA/CHMP/490007/2017 (...) in patients with impaired cell-mediated immunity deemed at risk. The applicant applied for the following indication: for prophylaxis of cytomegalovirus (CMV) reactivation and disease in adult CMV-seropositive recipients [R+] of an allogeneic haematopoietic stem cell transplant (HSCT). Following the CHMP positive opinion on this marketing authorisation, the Committee for Orphan Medicinal Products (COMP) reviewed the designation of Prevymis as an orphan medicinal product in the approved indication. More

2018 European Medicines Agency - EPARs

4. Assessment of non-visible haematuria

. Grossfeld GD, Litwin MS, Wolf JS, et al. Evaluation of asymptomatic microscopic hematuria in adults: the American Urological Association best practice policy - part I: definition, detection, prevalence and etiology. Urology. 2001;57:599-603. http://www.ncbi.nlm.nih.gov/pubmed/11306356?tool=bestpractice.com Tomson C, Porter T. Asymptomatic microscopic or dipstick haematuria in adults: which investigations for which patients? A review of the evidence. BJU Int. 2002;90:185-198. http://www.ncbi.nlm.nih.gov (...) /pubmed/12133052?tool=bestpractice.com Significance Although less commonly associated with malignancy than visible haematuria, NVH may signal cancer. National Institute for Health and Care Excellence. Suspected cancer: recognition and referral. July 2017 [internet publication]. https://www.nice.org.uk/guidance/ng12 However, about half of cases of NVH are idiopathic. Wollin T, Laroche B, Psooy K. Canadian guidelines for the management of asymptomatic microscopic hematuria in adults. Can Urol Assoc J

2018 BMJ Best Practice

5. Hematuria : Child

. o Summary of Literature Review Introduction/Background Hematuria is the presence of red blood cells in the urine, either visible to the eye (macroscopic hematuria) or as viewed under the microscope (microscopic hematuria). Detecting blood in the urine of a child may cause alarm to patients, parents, and physicians. The clinical evaluation of children with any form of hematuria begins with a meticulous history. Topics covered in the history commonly include urinary tract infection, strenuous (...) hematuria presents. This review focuses on the following clinical variations of childhood hematuria: ? Isolated hematuria (nonpainful, nontraumatic) ? Painful hematuria ? Renal trauma with macroscopic hematuria ? Renal trauma with microscopic hematuria In children with post-traumatic macroscopic hematuria, the role of imaging is to identify any evidence and the extent of renal or urinary tract injury. In other children, imaging has a role in identifying the cause of hematuria and to assess the size

2018 American College of Radiology

6. Hematuria in Adults

: Hematuria in Adults , Hematuria From Related Chapters II. Definition Significant Hematuria: 3 s/HPF or more III. Epidemiology Malignancy risk based on Hematuria type : 5% malignancy risk : 30-40% malignancy risk Malignancy risk increases over age 35-40 years old Age under 40 years with Hematuria Healthy men with Hematuria at one time: 39% Age over 40 years with Hematuria : 2.5% IV. Risk factors: Urologic malignancy risks (suggestive of significant cause of Hematuria) abuse Occupational exposures (...) (leather dye, , tire) Trichloroethylene Benzenes Aromatic amines agents (e.g. s) Age over 35 years Male gender Pelvic irradiation history Chronic indwelling foreign body Voiding symptoms suggestive of irritation Chronic history overuse V. Causes See See VI. Exam Men Genitourinary examination Rectal exam for size and nodularity Women: Pelvic examination l mass Uterine bleeding VII. Labs: All Hematuria cases tests with microscopic exam See Inadequate sample (contaminated with vaginal contents) Squamous

2018 FP Notebook

7. Microscopic Hematuria Causes in Adults

Microscopic Hematuria Causes in Adults Microscopic Hematuria Causes in Adults Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Microscopic Hematuria Causes in Adults Microscopic Hematuria Causes in Adults Aka: Microscopic Hematuria Causes in Adults , Adult Microscopic Hematuria Causes From Related Chapters II. Background Consider non-urine source (e.g. vagina or ) III. Causes: Most common of adult Hematuria by history Age Under age 40 years Genitourinary infection Over age 40 years Urinary tract cancer (up to 10% of cases) Prostatic Disease with pain Renal Vein Thrombosis Renal Artery with Hemorrhagic cystitis ( ) Prostatic

2015 FP Notebook

8. Hematuria as a Marker of Occult Urinary Tract Cancer: Advice for High-Value Care From the American College of Physicians

initiating further evaluation in all asymptomatic adults. High-Value Care Advice 4: Clinicians should refer for further urologic evaluation in all adults with gross hematuria, even if self-limited. High-Value Care Advice 5: Clinicians should consider urology referral for cystoscopy and imaging in adults with microscopically confirmed hematuria in the absence of some demonstrable benign cause. High-Value Care Advice 6: Clinicians should pursue evaluation of hematuria even if the patient is receiving (...) Care Advice 1: Clinicians should include gross hematuria in their routine review of systems and specifically ask all patients with microscopic hematuria about any history of gross hematuria. High-Value Care Advice 2: Clinicians should not use screening urinalysis for cancer detection in asymptomatic adults. High-Value Care Advice 3: Clinicians should confirm heme-positive results of dipstick testing with microscopic urinalysis that demonstrates 3 or more erythrocytes per high-powered field before

2016 American College of Physicians

9. Hematuria

of hematuria need imaging evaluation. Hematuria can originate from any site in the urinary tract and be due to a wide range of causes, which can be roughly divided into renal, urothelial, or prostatic causes. Thorough evaluation of gross hematuria is recommended, and this is usually done with a combination of clinical examination, cystoscopic evaluation, and urinary tract imaging [1-3]. Patients on anticoagulants who present with gross or microscopic hematuria have a sufficiently high prevalence (...) amounts of blood into the urine, so that several red cells per high-power field may be seen upon microscopic examination of the spun sediment. The low prevalence of clinically detectable disease in some groups of patients with asymptomatic microscopic hematuria has led some investigators to suggest that minimal microhematuria in an asymptomatic young adult needs no evaluation. Unfortunately, no threshold number of red blood cells per high-power field has been found that separates patients

2014 American College of Radiology

10. Diagnosis and Treatment of Non-Neurogenic Overactive Bladder (OAB) in Adults: an AUA/SUFU Guideline

of sufficient motor skills related to toileting habits. Urinalysis. A urinalysis to rule out UTI and hematuria should be performed. A urine culture is not necessary unless indication of infection (i.e., nitrites/leukocyte esterase on dipstick, pyuria/bacteriuria on microscopic exam) is found and may be done at the discretion of the clinician. If evidence of infection is detected, then a culture should be performed, the infection treated appropriately and the patient should be queried regarding symptoms once (...) . For complicated patients or refractory patients who have failed multiple OAB treatments, the choice of additional diagnostic tests depends on patient history and presentation and clinician judgment. In some cases, additional information may make clear that the patient has neurogenic OAB rather than non-neurogenic OAB and requires a different treatment plan. Patients with hematuria should be referred for a urologic work up. In the low-risk uncomplicated patient without microscopic hematuria, urine cytology

2019 American Urological Association

11. Diagnosis and Treatment of Non-Neurogenic Overactive Bladder (OAB) in Adults

/leukocyte esterase on dipstick, pyuria/bacteriuria on microscopic exam) is found and may be done at the discretion of the clinician. If evidence of infection is detected, then a culture should be performed, the infection treated appropriately and the patient should be queried regarding symptoms once the infection has cleared. If evidence of hematuria not associated with infection is found, then the patient should be referred for urologic evaluation. Close Guideline Statement 2 In some patients (...) non-neurogenic OAB and requires a different treatment plan. Patients with hematuria should be referred for a urologic work up. In the low-risk uncomplicated patient without microscopic hematuria, urine cytology is infrequently associated with atypia requiring further investigation, engendering costs and possibly resulting in morbidity. Urine cytology is not recommended in the routine evaluation of patients with uncomplicated OAB without hematuria who respond to therapy. Close Section 6: Treatments

2019 American Urological Association

12. Macroscopic haematuria - a urological approach

interests: none. Provenance and peer review: not commissioned; externally peer reviewed. References 1. o’connor oJ, Fitzgerald E, maher mm. imaging of haematuria. AJR Am J Roentgenol 2010;195:263–7. 2. Grossfield GD, Wolf Js, litwin ms, et al. Asymptomatic microscopic haematuria in adults: summary of the AuA Best Practice Policy Recommendations. Am Fam Physician 2001;63:1145–53. 3. mazhari R, Kimmel Pl. hematuria: an algorithmic approach to finding the cause. cleve clin J med 2002;69:870–84. 4 (...) haematuria. n Engl J med 2003;348:2330–7. 8. Grossfeld GD, carroll PR. Evaluation of asymp- tomatic microscopic hematuria. urol clin n Am 1998;25:661–76. 9. tomson c, Porter t . Asymptomatic microscopic or dipstick haematuria in adults: which investigations for which patients? A review of the evidence. BJu int 2002;90:185–98. 10. Johnson DW, Jones GR, mathew th, ludlow mJ, Doogue mP . chronic kidney disease and automatic reporting of estimated glomerular filtration rate: new developments and revised

2013 Clinical Practice Guidelines Portal

13. Microscopic haematuria: A rare presentation of typhoid fever. (Abstract)

Microscopic haematuria: A rare presentation of typhoid fever. Typhoid fever can cause a number of renal manifestations heretofore dubbed 'nephrotyphoid'. Haematuria in the absence of renal impairment is extremely rare among typhoid patients. We report a case of an adult who presented with a prolonged febrile illness and microscopic haematuria. Blood culture confirmed the diagnosis of typhoid and the patient was treated successfully with ceftriaxone. © The Author(s) 2014 Reprints and permissions

2014 Tropical Doctor

14. Minimal change disease and focal segmental glomerulosclerosis in adults: rituximab

% of cases is associated with a circulating protein factor that causes an increase in glomerular permeability; or secondary - the end product of a variety of pathological processes including glomerular hyperfiltration, healed glomerulonephritis, viral infection (HIV), and genetic mutation. Most patients with FSGS present with nephrotic syndrome (FSGS is the underlying diagnosis in 20% of adults with nephrotic syndrome), some with persistent proteinuria, and a few have haematuria as well as proteinuria (...) . Product overview Rituximab concentrate for solution for intravenous infusion (MabThera, Roche Products Limited) is licensed in adults for treating non-Hodgkin's lymphoma, chronic lymphocytic leukaemia, rheumatoid arthritis, and granulomatosis with polyangiitis and microscopic polyangiitis. It is administered as an intravenous infusion, which can take several hours, depending on the dose and rate of infusion. Rituximab is not licensed for treating MCD or FSGS and so use for this indication is off-label

2016 National Institute for Health and Clinical Excellence - Advice

15. Guideline for the management of adults with Systemic Lupus Erythematosus Full Text available with Trip Pro

Guideline for the management of adults with Systemic Lupus Erythematosus We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults | Rheumatology | Oxford Academic Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search filter search input (...) Article Navigation Close mobile search navigation Article navigation January 2018 Article Contents Article Navigation The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults Caroline Gordon Rheumatology Research Group, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham,Rheumatology Department, City Hospital, Sandwell and West Birmingham Hospitals NHS Trust,Rheumatology Department, University

2017 British Society for Rheumatology

16. Aspirin and the Risk of Microscopic Hematuria in Asymptomatic Screened Population

hematuria [ Time Frame: at the screening ] >4 RBC/HPF in urine microscopy Secondary Outcome Measures : Detection rate of significant cause for microscopic hematuria [ Time Frame: whitin 12 months after screening ] Among participants who had microscopic hematuria at the screening By imaging study or cystoscopy At the screening or within 12 months after screening Significant cause for microscopic hematuria urinary stone renal mass (benign or malignant / not simple cyst) urothelial cancer other lesions (...) Aspirin and the Risk of Microscopic Hematuria in Asymptomatic Screened Population Aspirin and the Risk of Microscopic Hematuria in Asymptomatic Screened Population - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding

2012 Clinical Trials

17. Hematuria in Adults

: Hematuria in Adults , Hematuria From Related Chapters II. Definition Significant Hematuria: 3 s/HPF or more III. Epidemiology Malignancy risk based on Hematuria type : 5% malignancy risk : 30-40% malignancy risk Malignancy risk increases over age 35-40 years old Age under 40 years with Hematuria Healthy men with Hematuria at one time: 39% Age over 40 years with Hematuria : 2.5% IV. Risk factors: Urologic malignancy risks (suggestive of significant cause of Hematuria) abuse Occupational exposures (...) (leather dye, , tire) Trichloroethylene Benzenes Aromatic amines agents (e.g. s) Age over 35 years Male gender Pelvic irradiation history Chronic indwelling foreign body Voiding symptoms suggestive of irritation Chronic history overuse V. Causes See See VI. Exam Men Genitourinary examination Rectal exam for size and nodularity Women: Pelvic examination l mass Uterine bleeding VII. Labs: All Hematuria cases tests with microscopic exam See Inadequate sample (contaminated with vaginal contents) Squamous

2015 FP Notebook

18. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications Full Text available with Trip Pro

the serodiagnostic and PCR approaches can be standardized and validated in a sufficient number of cases of these rare types of IE, the aforementioned technical problems are resolved, and the availability of such assays becomes more widespread. The expansion of minor criteria to include elevated erythrocyte sedimentation rate or C-reactive protein, the presence of newly diagnosed clubbing, splenomegaly, and microscopic hematuria also has been proposed. In a study of 100 consecutive cases of pathologically proven (...) Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search March 2019 March 2019 March 2019 March 2019 March 2019 February 2019 February 2019 February 2019 February 2019 January 2019 January 2019 January 2019 January 2019 January 2019 Free Access article Share

2016 Infectious Diseases Society of America

19. Diagnosis, Evaluation and Follow-up of Asymptomatic Microhematuria (AMH) in Adults

benign cause. A positive dipstick does not define AMH, and evaluation should be based solely on findings from microscopic examination of urinary sediment and not on a dipstick reading. A positive dipstick reading merits microscopic examination to confirm or refute the diagnosis of AMH. Expert Opinion 2. The assessment of the asymptomatic microhematuria patient should include a careful history, physical examination, and laboratory examination to rule out benign causes of AMH such as infection (...) -contaminated urinalysis with no evidence of infection for which a combination of microscopic urinalysis and dipstick excludes other abnormalities such as pyuria, bacteriuria, and contaminants. In addition, benign causes, such as menstruation, vigorous exercise, viral illness, trauma, and infection, have been excluded. Literature Limitations and Interpretation. The Panel notes that requiring a single positive urinalysis verified by microscopy is a departure from the 2001 AUA Best Practice Statement

2016 American Urological Association

20. Management of Dengue Infection in Adults

Figure 2: Dengue Case Fatality Rate (CFR) By Age Group In Malaysia, 2004-20142 CPG Management of Dengue Infection In Adults (Third Edition) 2015 3 DENGUE VIRUS AND SEROTYPE TRENDS IN MALAYSIA 2. Dengue infection is caused by dengue virus which is a mosquito-borne flavivirus. It is transmitted by Aedes aegypti and Aedes albopictus. There are four distinct serotypes, DENV-1,2,3 and 4. Each episode of infection induces a life-long protective immunity to the homologous serotype but confers only partial (...) Management of Dengue Infection in Adults 1 CPG Management of Dengue Infection In Adults (Third Edition) 20152 CPG Management of Dengue Infection In Adults (Third Edition) 2015 3 Published by: Malaysia Health Technology Assessment Section (MaHTAS) Medical Development Division, Ministry of Health Malaysia Level 4, Block E1, Precinct 1 Federal Government Administrative Centre 62590, Putrajaya, Malaysia Copyright The copyright owner of this publication is MaHTAS. Content may be reproduced in any

2015 Ministry of Health, Malaysia

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