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Meperidine

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161. Midazolam with meperidine or fentanyl for colonoscopy: results of a randomized trial. (PubMed)

Midazolam with meperidine or fentanyl for colonoscopy: results of a randomized trial. A combination of midazolam and opioid is usually used to achieve sedation and analgesia during colonoscopy. Two commonly used opioids are meperidine and fentanyl, but few studies have compared their efficacy.This randomized trial aimed to compare the efficacy and recovery time of 2 sedation regimens consisting of midazolam in combination with either meperidine or fentanyl.A total of 300 consecutive, unselected (...) adults attending outpatient colonoscopy at a District General Hospital were enrolled with informed consent and randomized to receive midazolam with meperidine or fentanyl. Data for procedure times, perceived discomfort (according to standard 100-mm visual analog scales [VAS]), and recovery time were collected. Patients and all endoscopy staff directly involved with the procedure were blinded to the regimen used.Primary: patients' experience of pain (postrecovery VAS score); secondary: recovery time.A

2009 Gastrointestinal endoscopy

162. [Comparative study between analgesic efficacy and safety of meperidine compared with lidocaine periprostatic infiltration in transrectal ultrasound guided prostate biopsy]. (PubMed)

[Comparative study between analgesic efficacy and safety of meperidine compared with lidocaine periprostatic infiltration in transrectal ultrasound guided prostate biopsy]. To assess the efficacy of intravenous analgesia with meperidine compared to periprostatic plexus infiltration with lidocaine, and safety of periprostatic local anesthesia.A prospective randomized study with 100 patients undergoing first or second prostate biopsy. We distribute patients in two groups, group A (50 patients (...) ) which was administered 50 mg of intravenous meperidine and group B (50 patients) receiving 5 mL of lidocaine 2% in the angle between prostate and seminal vesicles. Pain was assessed by Visual Analog Scale (VAS) and a questionnaire about the emotional impact. Procedure safety was obtained by telephone questionnaire about prostate biopsy complications. The statistical analysis used was chi square test, Student's t test and Kruskal-Wallis no parametric test.Median age was 66 years (47-80) and both

2009 Actas urologicas espanolas

163. Perineural meperidine blocks nerve conduction in a dose-related manner: a randomized double-blind study. (PubMed)

Perineural meperidine blocks nerve conduction in a dose-related manner: a randomized double-blind study. Meperidine has been shown to exhibit a sensory block in peripheral nerves. However, its motor blockade ability is controversial. The aim of this study was to investigate, electroneurographically, the ability of meperidine to inhibit conduction in both sensory and motor fibres in the ulnar nerve.The study was conducted in a double-blind, placebo-controlled fashion. Eighteen healthy volunteers (...) were randomized into three groups (Saline, meperidine 1% and meperidine 2%). Three millilitre of the study solution was administered to the ulnar nerve perineurally at the level of the wrist by the guidance of a nerve stimulator. Sensory nerve action potential (SNAP) and compound motor action potential (CMAP) amplitudes were recorded. At least a 20% decrease in the initial response amplitude was accepted as a block.The number of individuals with sensory and motor block with saline, meperidine 1

2009 Acta Anaesthesiologica Scandinavica

164. Sedation with midazolam versus midazolam plus meperidine for routine colonoscopy: a prospective, randomized, controlled study. (PubMed)

Sedation with midazolam versus midazolam plus meperidine for routine colonoscopy: a prospective, randomized, controlled study. The major goals of analgesia and sedation are to provide pain control and anxiolysis and to facilitate therapeutic and diagnostic interventions. A combination of midazolam and an opioid is usually administered to achieve sedation and analgesia during colonoscopy. However, the value of adding analgesics to sedative agents has not been well evaluated. In this study, we (...) compared the efficacy and safety of midazolam versus midazolam plus meperidine for colonoscopy.A total of 74 patients admitted for routine colonoscopy to our hospital between September 2008 and March 2009 were eligible for the study. The midazolam group received midazolam (n=34) and the midazolam/meperidine group received midazolam plus meperidine (n=40). Data regarding the procedure times, degree of pain (determined according to the standard visual analog scales and recovery time were collected.There

2009 The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology

165. Postoperative pain control after cesarean section: can diclofenac sodium be used instead of meperidine? (PubMed)

Postoperative pain control after cesarean section: can diclofenac sodium be used instead of meperidine? To determine the advantages and disadvantages of the use of diclofenac sodium instead of meperidine for postcesarean section pain control.A total of 130 patients who had undergone cesarean section at the Department of Obstetrics and Gynecology of Gazi University Hospital were prospectively randomised to receive one of two postoperative pain control regimens. The first group of patients (...) received intramuscular diclofenac sodium at a dose of 2 x 75 mg and additional breakthrough meperidine was given intramuscularly at 50 mg dosages each time, if necessary. Patients in the second group received only 6 x 50 mg meperidine.Twenty-seven of the 65 patients in the diclofenac group complained of unrelieved pain within the subsequent 24 h postoperatively. Patients receiving diclofenac alone or a combination of diclofenac + meperidine were less sedated and the time to the first passing of flatus

2009 The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

166. A Trial Comparing Propofol to Midazolam Plus Meperidine Sedation for Outpatient Colonoscopy

A Trial Comparing Propofol to Midazolam Plus Meperidine Sedation for Outpatient Colonoscopy A Trial Comparing Propofol to Midazolam Plus Meperidine Sedation for Outpatient Colonoscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. A Trial Comparing Propofol to Midazolam Plus Meperidine Sedation for Outpatient Colonoscopy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00848861 Recruitment Status : Completed First Posted : February 20, 2009 Last Update Posted : February 20, 2009 Sponsor: University

2009 Clinical Trials

169. Use of Local Anesthesia for Pediatric Dental Patients

of local anesthetics and also elevate arterial carbon dioxide, both of which will increase CNS sensitivity to convulsions. In addition, narcotics such as meperidine have convulsant properties when excessive doses are administered. For patients undergoing general anesthesia, the anesthesia care provider needs to be aware of the concomitant use of a local anesthetic containing epinephrine, as epinephrine can produce dysrhythmias when used with halogenated hydro- carbons (e.g., halothane). 1 Local

2015 American Academy of Pediatric Dentistry

170. Safety and efficacy of therapeutic hypothermia for acute ischemic stroke. Systematic review and Meta-analysis

Chinese medicine (difference in NIHSS score at 24 hours -4 ±0.6 and -1.5±0.4 respectively). However, on the other study the neurological outcome was more favourable in the group treated with thrombolysis alone (difference in NIHSS score at 24 hours (+3 versus -2.5 respectively) possibly due to the sedative action of meperidine used in the intervention group. Among the parameters related to patient morbidity, differences were found with respect to high dose and duration of norepinephirne in patients

2014 Health Technology Assessment (HTA) Database.

171. Effect of Entonox on reducing the need for Pethidine and the Relevant Fetal and Maternal Complications for Painless Labor. (PubMed)

Effect of Entonox on reducing the need for Pethidine and the Relevant Fetal and Maternal Complications for Painless Labor. Pain relief during labour is one of the major concerns in obstetrics; severe labor pain causes fear of the next pregnancy, and interferes with the mother's family relationship.The aim of this study was to evaluate the analgesic effects of Entonox during labor on reducing the need for pethidine (Meperidine) and fetal-maternal complications.This double-blind randomized

Full Text available with Trip Pro

2016 Electronic physician

176. Management of Chronic Kidney Disease (CKD) in Primary Care

Digoxin o Dofetilide o Potassium-sparing diuretics • RAAS blockers o ACEIs o ARBs o Aliskiren o Eplerenone, spironolactone • Anticoagulants o Apixaban o Dabigatran o Rivaroxaban o Low molecular weight heparins • Opioid analgesics o Codeine o Fentanyl o Hydrocodone o Hydromorphone o Meperidine o Methadone o Morphine o Oxycodone o Oxymorphone o Tapentadol o Tramadol • NSAIDs • Gabapentin • Levetiracetam • Lithium • Memantine • Risperidone, Paliperidone • Antidepressants o Bupropion o Citalopram o

2014 VA/DoD Clinical Practice Guidelines

177. Sedative techniques for endoscopic retrograde cholangiopancreatography. (PubMed)

sedation using midazolam and meperidine with deep sedation using propofol in patients undergoing ERCP procedures. All sedation was administered by non-anaesthetic personnel. Due to the clinical heterogeneity of the studies we decided to review the papers from a narrative perspective as opposed to a full meta-analysis. Our primary outcome measures included mortality, major complications and inability to complete the procedure due to sedation-related problems. Secondary outcomes encompassed sedation (...) considerably. The studies showed either moderate or high risk of bias.Results from individual studies suggested that patients have a better recovery profile after propofol sedation for ERCP procedures than after midazolam and meperidine sedation. As there was no difference between the two sedation techniques as regards safety, propofol sedation is probably preferred for patients undergoing ERCP procedures. However, in all of the studies that were identified only non-anaesthesia personnel were involved

2012 Cochrane

178. Controversies in Migraine Management

in 2008. 34 This review found that patient outcomes achieved with the opioid meperidine were no better than ketorolac (a non-steroidal anti-inflammatory drug, or NSAID) and inferior to dihydroergotamine (one of a group ©Institute for Clinical and Economic Review, 2014 Page ES8 of drugs called ergot alkaloids that works by narrowing the blood vessels around the brain and affecting blood flow patterns) and anti-emetics (drugs used to reduce vomiting and nausea). Despite societal attention to the overuse (...) , antiemetics (chlorpromazine, droperidol, metoclopramide, prochlorperazine, promethazine), dexamethasone, and opioids (meperidine, tramadol, nalbuphine). 32-35 Ketorolac is the preferred first-line agent because of its minimal side effects and at least eight randomized trials demonstrating equivalence or superiority to parenteral sumatriptan and the antiemetics. The evidence about opioids will be discussed in detail in the evidence review. Antiemetic therapy, such as metoclopramide, can facilitate the use

2014 California Technology Assessment Forum

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