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161. Use of Local Anesthesia for Pediatric Dental Patients

of local anesthetics and also elevate arterial carbon dioxide, both of which will increase CNS sensitivity to convulsions. In addition, narcotics such as meperidine have convulsant properties when excessive doses are administered. For patients undergoing general anesthesia, the anesthesia care provider needs to be aware of the concomitant use of a local anesthetic containing epinephrine, as epinephrine can produce dysrhythmias when used with halogenated hydro- carbons (e.g., halothane). 1 Local

2015 American Academy of Pediatric Dentistry

162. Safety and efficacy of therapeutic hypothermia for acute ischemic stroke. Systematic review and Meta-analysis

Chinese medicine (difference in NIHSS score at 24 hours -4 ±0.6 and -1.5±0.4 respectively). However, on the other study the neurological outcome was more favourable in the group treated with thrombolysis alone (difference in NIHSS score at 24 hours (+3 versus -2.5 respectively) possibly due to the sedative action of meperidine used in the intervention group. Among the parameters related to patient morbidity, differences were found with respect to high dose and duration of norepinephirne in patients

2014 Health Technology Assessment (HTA) Database.

163. Effect of Entonox on reducing the need for Pethidine and the Relevant Fetal and Maternal Complications for Painless Labor. (PubMed)

Effect of Entonox on reducing the need for Pethidine and the Relevant Fetal and Maternal Complications for Painless Labor. Pain relief during labour is one of the major concerns in obstetrics; severe labor pain causes fear of the next pregnancy, and interferes with the mother's family relationship.The aim of this study was to evaluate the analgesic effects of Entonox during labor on reducing the need for pethidine (Meperidine) and fetal-maternal complications.This double-blind randomized

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2016 Electronic physician

169. Management of Chronic Kidney Disease (CKD) in Primary Care

Digoxin o Dofetilide o Potassium-sparing diuretics • RAAS blockers o ACEIs o ARBs o Aliskiren o Eplerenone, spironolactone • Anticoagulants o Apixaban o Dabigatran o Rivaroxaban o Low molecular weight heparins • Opioid analgesics o Codeine o Fentanyl o Hydrocodone o Hydromorphone o Meperidine o Methadone o Morphine o Oxycodone o Oxymorphone o Tapentadol o Tramadol • NSAIDs • Gabapentin • Levetiracetam • Lithium • Memantine • Risperidone, Paliperidone • Antidepressants o Bupropion o Citalopram o

2014 VA/DoD Clinical Practice Guidelines

170. Sedative techniques for endoscopic retrograde cholangiopancreatography. (PubMed)

sedation using midazolam and meperidine with deep sedation using propofol in patients undergoing ERCP procedures. All sedation was administered by non-anaesthetic personnel. Due to the clinical heterogeneity of the studies we decided to review the papers from a narrative perspective as opposed to a full meta-analysis. Our primary outcome measures included mortality, major complications and inability to complete the procedure due to sedation-related problems. Secondary outcomes encompassed sedation (...) considerably. The studies showed either moderate or high risk of bias.Results from individual studies suggested that patients have a better recovery profile after propofol sedation for ERCP procedures than after midazolam and meperidine sedation. As there was no difference between the two sedation techniques as regards safety, propofol sedation is probably preferred for patients undergoing ERCP procedures. However, in all of the studies that were identified only non-anaesthesia personnel were involved

2012 Cochrane

171. Controversies in Migraine Management

in 2008. 34 This review found that patient outcomes achieved with the opioid meperidine were no better than ketorolac (a non-steroidal anti-inflammatory drug, or NSAID) and inferior to dihydroergotamine (one of a group ©Institute for Clinical and Economic Review, 2014 Page ES8 of drugs called ergot alkaloids that works by narrowing the blood vessels around the brain and affecting blood flow patterns) and anti-emetics (drugs used to reduce vomiting and nausea). Despite societal attention to the overuse (...) , antiemetics (chlorpromazine, droperidol, metoclopramide, prochlorperazine, promethazine), dexamethasone, and opioids (meperidine, tramadol, nalbuphine). 32-35 Ketorolac is the preferred first-line agent because of its minimal side effects and at least eight randomized trials demonstrating equivalence or superiority to parenteral sumatriptan and the antiemetics. The evidence about opioids will be discussed in detail in the evidence review. Antiemetic therapy, such as metoclopramide, can facilitate the use

2014 California Technology Assessment Forum

173. Topical Transdermally Delivered Lidocaine and Benzocaine Compared to Compounded Lidocaine/Tetracaine During Microfocused Ultrasound With Visualization Treatment. (PubMed)

%/tetracaine 7% (23/7) to mitigate discomfort during MFU-V treatment.This was a randomized, double-blinded, split-face study. One hour before MFU-V, subjects (N=14 females) received 50 mg IM meperidine/25 mg IM promethazine/5 mg oral diazepam. Fifteen minutes before treatment, 1 side of the face was treated with 1 application of 4% lidocaine, followed by 1 application of 20% benzocaine; the contralateral side was treated with 2 applications of 23/7 (to maintain blinding). Numbness was assessed by blinded

2018 Journal of drugs in dermatology : JDD

174. [Effect of continuous and single shot adductor canal blocks for postoperative analgesia and early rehabilitation after total knee arthroplasty]. (PubMed)

patients in group A and 7 patients in group B requiring meperidine hydrochloride (50 mg/time) within 24 hours, and 3 patients in group A and 7 patients in group B at 24 to 48 hours, and 1 patient in group A and 3 patients in group B at 48 to 72 hours. Effusion in the catheter site occurred in 2 cases of group A, but no catheter extrusion occurred.Continuous ACB is superior in analgesia both at rest and during activity and opioid consumption compared with single shot ACB after TKA. And the quadriceps

2018 Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery

175. Evaluation of hyoscine N-butyl bromide efficacy on the prevention of catheter-related bladder discomfort after transurethral resection of prostate: a randomized, double-blind control trial. (PubMed)

, statistically significant less CRBD was seen in the treatment group comparing to the control group (P ≤ 0.05 and P ≤ 0.007). The total utilized meperidine dose during PACU stay and the time to discharge for the intervention group were significantly lower than those for the control group (P ≤ 0.0001) with no significant difference in adverse effects (P > 0.05).Hyoscine N-butyl bromide could reduce the severity of CRBD related to TURP in patients with BPH and their need for analgesic consumption either

2018 International urology and nephrology

176. The effect of rectus muscle re-approximation at cesarean delivery on pain perceived after operation: a randomized control trial. (PubMed)

complication were also assessed.Postoperative pain score at the end of the first 24 hours and at the end of the next 24 hours were significantly higher among the group of rectus muscle reapproximation (a difference in VAS pain score of: 5, 95% confidence interval: 0.1-11, p value: .02) and (a difference of 1, 95% confidence interval: 0.1-2.9, p value: .01), respectively. As regards the narcotic use in the first 24 hours after cesarean section, in the form of injections of meperidine 50 mg

2018 The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

177. Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior Immunotherapy

treatment. Has received prior therapy with an IDO inhibiting agent. Has a known history of Human Immunodeficiency Virus (HIV) (HIV 1/2 antibodies). Has known active Hepatitis B (e.g., HBsAg reactive) or Hepatitis C (e.g., HCV RNA [qualitative] is detected). Has received a live vaccine within 30 days of planned start of study therapy. Has received MAO-inhibitors (MAOI) or drug which has significant MAOI activity (meperidine, linezolid, methylene blue) within the 21 days before screening. History

2018 Clinical Trials

178. A Study of Epacadostat, an IDO1 Inhibitor, in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

of the trial, starting with the pre-screening or screening visit through 120 days after the last dose of study treatment(s). Inability to comply with protocol required procedures Subjects receiving Monoamine Oxidase Inhibitors (MAOIs) or drug which has significant MAOI activity (meperidine, linezolid, methylene blue) within the 21 days before screening. Any history of Serotonin Syndrome (SS) after receiving serotonergic drugs. History or presence of an abnormal electrocardiogram (ECG

2018 Clinical Trials

179. Wound Infiltration With Ketorolac Versus Lidocaine for Postoperative Analgesia After Total Abdominal Hysterectomy

1, 2, 4, 6, 12, 18 and 24 h later. Patients will be instructed about the usage of VAS scalebefore the operation. The total analgesic consumption [ Time Frame: First 24 hours postoperatively ] Postoperative analgesia will be provided with intramuscular (IM) meperidine 50 mg to both groups when the VAS score is ≥4. The total meperidine consumption will be recorded. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important

2018 Clinical Trials

180. HIgh Dose Thymoglobulin Instead of Cyclosporine With a Low Dose of Thymoglobulin for GVHD Prophylaxis

in >5% difference from calculated dose. Foothills Medical Center Unit 57 standard practice followed for ATG infusion. ATG premeds include methylprednisolone 40 mg IVPB, acetaminophen 1000 mg PO & diphenhydramine 50 mg IVPB. Acetaminophen 1000 mg PO & diphenhydramine 50 mg IVPB can be repeated in 4-6 hrs PRN for flu-like symptoms/fever/chills. Meperidine 25-50 mg IVPB given PRN every 4 hrs for rigors. MTX is given 15 mg/m2 IV on day +1 & 10 mg/m2 on days +3, +6 & +11 posttransplant. First dose

2018 Clinical Trials

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