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Meperidine

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61. Comparison of the Analgesic Efficacy of Dexketoprofen Trometamol and Meperidine HCl in the Relief of Renal Colic. (PubMed)

Comparison of the Analgesic Efficacy of Dexketoprofen Trometamol and Meperidine HCl in the Relief of Renal Colic. In this study, the analgesic effects of dexketoprofen trometamol and meperidine hydrochloride were compared in patients diagnosed with renal colic. This study was a prospective, randomized, double-blind study. Fifty-two patients, between the ages of 18 and 70 years who were diagnosed with renal colic, were enrolled in the study after obtaining ethics committee approval. Before drug (...) injection, dexketoprofen trometamol and meperidine hydrochloride were placed in closed envelopes, and the patients were randomly given a single dose of intravenous infusion for 20 minutes. Severity of pain and symptoms was evaluated with the numerical rating scale and renal colic symptom score for each patient immediately before administration of drugs and 30 minutes after the end of the application. At the same time, systolic arterial blood pressure, diastolic arterial pressure, respiratory rate, heart

2013 American journal of therapeutics

62. Comparison of effects of epidural bupivacaine and intravenous meperidine analgesia on patient recovery following elective abdominal aortic surgery. (PubMed)

Comparison of effects of epidural bupivacaine and intravenous meperidine analgesia on patient recovery following elective abdominal aortic surgery. The efficacy of epidural anesthesia and analgesia in management of perioperative stress has been established. Perioperative pain management strategies decrease surgical complications and aid recovery. In this study, we aimed to document and compare the efficacy of epidural bupivacaine and intravenous meperidine on recovery of patients with elective (...) abdominal aortic surgery performed under general anesthesia.Patients undergoing elective abdominal aortic surgery between February 2009 and November 2011 were studied prospectively. Patients were randomized into epidural bupivacaine (n=40) and intravenous meperidine (n=40) groups regarding postoperative analgesia strategy. The preoperative demographic characteristics, perioperative outcomes, postoperative adverse effects of analgesia strategy, time to initiate oral intake, sedation scores, visual

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2013 Medical science monitor : international medical journal of experimental and clinical research

63. Meperidine as the single sedative agent during esophagogastroduodenoscopy, a double-blind, randomized controlled study. (PubMed)

Meperidine as the single sedative agent during esophagogastroduodenoscopy, a double-blind, randomized controlled study. In Taiwan, unsedated esophagogastroduodenoscopy (EGD) is widely used, but it is uncomfortable for some patients. While meperidine has been adopted in colonoscopy, its use in EGD has not received extensive attention. This was a prospective study to investigate the use of meperidine as a single sedative agent during EGD.One hundred and forty patients were randomized to receive (...) either 25-mg meperidine (n = 70) or placebo (n = 70) by intramuscular injection before EGD. The primary outcome was patient discomfort scores. The secondary outcomes included patient, endoscopist, and EGD-related variables.Patients in the meperidine group reported less discomfort during esophageal intubation (median score of 2.0 and interquartile range [IQR] of 0-4.0 vs median score of 4.8 and IQR of 1.7-7.0, respectively; P < 0.001) and during the procedure (median score of 1.0 [IQR 0-3.1] vs 3.5

2013 Journal of gastroenterology and hepatology

64. Two dosages of remifentanil for patient-controlled analgesia vs. meperidine during colonoscopy: A prospective randomized controlled trial. (PubMed)

Two dosages of remifentanil for patient-controlled analgesia vs. meperidine during colonoscopy: A prospective randomized controlled trial. BACKGROUND AND STUDY: Combined use of opiates and benzodiazepines often results in delayed discharge after colonoscopy.To compare sedation quality of two dosages of patient controlled analgesia remifentanil with one another and with that of a midazolam-meperidine association during colonoscopy.Ninety patients undergoing colonoscopy were randomly assigned (...) to three groups. Group M received a meperidine bolus (0.7 mg/kg) and sham patient controlled analgesia. Group R1 received remifentanil 0.5 μg/kg and group R2 remifentanil 0.8 μg/kg together with a patient-controlled analgesia pump injecting further boluses (2-min lock-out). Technical difficulties of the examination, gastroenterologist's and patient's satisfaction with sedoanalgesia were evaluated after colonoscopy on a 100 mm Visual Analogue Scale. Patient's satisfaction was assessed 24 h later.Group M

2013 Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

65. Adjuvant intrathecal meperidine prevents shivering following spinal anesthesia: a meta-analysis of randomized controlled trials with trial sequential analysis

Adjuvant intrathecal meperidine prevents shivering following spinal anesthesia: a meta-analysis of randomized controlled trials with trial sequential analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr

2016 PROSPERO

66. The Effect of Different Intrathecal Doses of Meperidine on Shivering during Delivery Under Spinal Anesthesia. (PubMed)

The Effect of Different Intrathecal Doses of Meperidine on Shivering during Delivery Under Spinal Anesthesia. This study was performed to compare the effect of different doses of intrathecal meperidine on the incidence and intensity of shivering and other side-effects after spinal anesthesia for cesarean delivery.One hundred and fifty-six parturient women scheduled for elective cesarean delivery were enrolled in four groups. Spinal anesthesia consisted of heavy bupivacaine 0.5% (10 mg (...) ) in the standard group (Group I), heavy bupivacaine 0.5% (10 mg) plus meperidine (0.2 mg per kg) in Group II, heavy bupivacaine 0.5% (10 mg) plus meperidine (0.3 mg per kg) in Group III, heavy bupivacaine 0.5% (10 mg) plus meperidine (0.4 mg per kg) in Group IV. The signs and symptoms were recorded by an observer unaware of the study groups. Data were analyzed using analysis of variance, Kruskal-Wallis H-test and chi-square. A P value less than 0.05 was considered to be significant.The systolic blood pressure

2012 International journal of preventive medicine

67. Meperidine

Meperidine Meperidine Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Meperidine Meperidine Aka: Meperidine , Demerol From Related (...) over intramuscular No dosing adjustment needed for IV versus IM Dosing frequency is often dosed too infrequently Duration of action is only 3 hours Avoid more than 2-3 doses due to accumulation Often administered with ( ) 25 to 50 mg (0.5 mg/kg) IM q4-6 hours no longer routinely recommended Does not potentiate Meperidine requires intramuscular dosing (sclerosing) Only indicated for Meperidine induced (20%) Consider alternative intravenous Example: Dose only as needed for or VI. Disadvantages Toxic

2015 FP Notebook

68. Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women

Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01555671 Recruitment Status : Completed First Posted : March 15, 2012 Last Update Posted

2012 Clinical Trials

69. A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus

A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01741259 Recruitment Status : Completed First Posted : December 4, 2012 Results First Posted : October 25, 2017 Last Update Posted : October 25

2012 Clinical Trials

70. Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy

Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy (remifentanil) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01693185 Recruitment Status : Completed First Posted : September 26, 2012 Results First Posted : June 18, 2014 Last Update Posted : June 18, 2014 Sponsor: Konkuk

2012 Clinical Trials

71. Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy

Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Meperidine (...) Chi General Hospital Study Details Study Description Go to Brief Summary: Upper endoscopy is uncomfortable for most patients. Meperidine has both sedative and analgesic effects, so its use may be helpful for patients receiving upper endoscopy. Condition or disease Intervention/treatment Phase Esophagogastroduodenoscopy Drug: Meperidine Drug: normal saline Not Applicable Detailed Description: Unsedated esophagogastroduodenoscopy (EGD) is a useful tool for upper gastrointestinal tract examination

2012 Clinical Trials

72. Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine.

Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. (ERCP) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01709422 Recruitment Status : Completed First Posted : October 18, 2012 Results First Posted : August 27, 2013 Last Update

2012 Clinical Trials

73. Meperidine for uterine dystocia and its effect on duration of labor and neonatal acid-base status: a randomized clinical trial. (PubMed)

Meperidine for uterine dystocia and its effect on duration of labor and neonatal acid-base status: a randomized clinical trial. The aim of this study was to evaluate the effectiveness of meperidine, administered during the first stage of labor in patients with uterine dystocia, on the duration of labor and neonatal acid-base status at birth.We randomly assigned 240 nulliparous women with a singleton pregnancy at term who were diagnosed with uterine dystocia in labor at 4-6-cm cervical (...) dilatation to receive either a single dose of 50 mg meperidine in 10 mL of saline (slow intravenous injection over 2 min) or 10 mL of isotonic saline (control group). The primary outcome measures were duration of labor (from the time of beginning of the intervention to the time of the expulsion of the fetal head) and umbilical cord arterial acid-base status.The evidence revealed no statistically significant difference between the two groups in length of labor (188.2 ± 92.3 min in the meperidine group

2012 The journal of obstetrics and gynaecology research

74. Intraperitoneal ropivacaine or ropivacaine plus meperidine for laparoscopic gynecological procedures.

Intraperitoneal ropivacaine or ropivacaine plus meperidine for laparoscopic gynecological procedures. Postoperative pain after laparoscopic surgery is less intense than after laparotomy and patients may benefit from an intraperitoneal injection of local anesthetic and opioids. We aimed to compare intraperitoneal 0.75% ropivacaine with 0.75% ropivacaine plus meperidine for postoperative analgesia in patients undergoing gynecologic laparoscopy.At the end of gynecologic laparoscopy, in a double (...) -blind, randomized manner, one of the following injections was given intraperitoneally. Patients were allocated into three groups: Patients in R Group (n=18) were given 0.75% ropivacaine 3 mg/kg in 200 mL saline; patients in RM Group (n=17) were given meperidine 50 mg plus 0.75% ropivacaine 3 mg/kg in 200 mL saline; patients in C Group (n=18) were given 200 mL saline through the trocars. All patients were given diclofenac sodium when they had pain (VAS 3) and 1 mg/kg meperidine i.v. was also given

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2012 Aǧrı : Ağrı (Algoloji) Derneği'nin Yayın organıdır = The journal of the Turkish Society of Algology

75. The effects of Adding Meperidine to Heavy Intrathecal Lidocaine on Hemodynamic Changes and Blood Loss in Open Prostatectomy: A Randomized Double-Blind Clinical Trial. (PubMed)

The effects of Adding Meperidine to Heavy Intrathecal Lidocaine on Hemodynamic Changes and Blood Loss in Open Prostatectomy: A Randomized Double-Blind Clinical Trial. Clinical investigations have reported several anesthetic properties of intrathecal injections of meperidine. The purpose of this study was to investigate the effect of adding meperidine to intrathecal heavy lidocaine on hemodynamic changes and blood loss in patients undergoing elective suprapubic open prostatectomy.In a randomized (...) double-blind clinical trial, 77 patients candidate for elective suprapubic open prostatectomy were allocated to two equal groups. All patients in the control and experimental groups received heavy lidocaine intrathecally. A low dose of meperidine was added to lidocaine in the experiment group. Changes in blood pressure and heart rate were measured and documented in several intervals. Blood loss, transfusion rate, shivering, nausea, vomiting, need to an analgesic drug, and transient neurologic

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2012 Iranian journal of medical sciences

76. Comparison of meperidine versus hyoscine during colonoscopy in the elderly: a prospective randomized study. (PubMed)

Comparison of meperidine versus hyoscine during colonoscopy in the elderly: a prospective randomized study. Colonoscopy is the gold standard in diagnosis of diseases of the colon. Sedation and antispasmodic agents are recommended during colonoscopy. Age is a limiting factor when the surgeon is deciding whether to use these medications or not.One hundred twenty patients older than 65 years of age were randomized into two groups. The first group (n=60) received 2 mg of midazolam and 25 mg (...) of meperidine intravenously. The second group (n=60) received 2 mg of midazolam and 20 mg of hyoscine N-butylbromide intravenously. The data collected were colonoscopy procedure time, time to cecum, visual analog pain scale, systolic blood pressure before and after the procedure, pulse, partial oxygen pressure, comfort of the endoscopist, the modified observer's assessment of alertness/sedation scale, and morbidity.Total colonoscopy and cecal reach times were shorter in Group 2 (19.58±4.82 minutes and 10.57

2012 Journal of laparoendoscopic & advanced surgical techniques. Part A

77. Intrathecal meperidine reduces intraoperative shivering during transurethral prostatectomy in elderly patients. (PubMed)

Intrathecal meperidine reduces intraoperative shivering during transurethral prostatectomy in elderly patients. Shivering is a frequent event during the perioperative period. We performed a prospective, randomized, double-blind study to determine whether intrathecal meperidine (0.2 mg/kg) decreases the incidence and intensity of shivering after spinal anesthesia for transurethral operations.Fifty patients scheduled for elective transurethral resection operations under spinal anesthesia were (...) randomly allocated to two groups. Spinal anesthesia consisted of 0.5% hyperbaric bupivacaine 8 mg and, mperidine (0.2 mg/kg) (meperidine group) or, normal saline (saline group). Data collection, including sensory block level (by pinprick), blood pressure, heart rate, sublingual temperature, incidence and intensity of shivering, pruritus, nausea, and vomiting was performed at 10 minute intervals.The incidence and intensity of shivering was significantly less in the meperidine group than saline group (P

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2011 Korean journal of anesthesiology

78. Is Meperidine the Drug That Just Won't Die? (PubMed)

Is Meperidine the Drug That Just Won't Die? 22479158 2012 08 23 2018 11 13 2331-348X 16 3 2011 Jul The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG J Pediatr Pharmacol Ther Is Meperidine the Drug That Just Won't Die? 167-9 10.5863/1551-6776-16.3.167 Buck Marcia L ML Department of Pharmacy Services, University of Virginia Children's Hospital, Charlottesville, Virginia, and Department of Pediatrics, School of Medicine, University of Virginia (...) , Charlottesville, Virginia. eng Journal Article United States J Pediatr Pharmacol Ther 101089851 1551-6776 adverse drug effect formulary hospital meperidine 2012 4 6 6 0 2012 4 6 6 0 2012 4 6 6 1 ppublish 22479158 10.5863/1551-6776-16.3.167 PMC3292527 J Pediatr Pharmacol Ther. 2011 Jul;16(3):185-90 22479160 Pharmacotherapy. 2004 Jun;24(6):776-83 15222668 Clin Pharm. 1990 May;9(5):337-8 2350937 Pediatrics. 2001 Sep;108(3):793-7 11533354 Anesth Analg. 2000 Feb;90(2):299-305 10648310 Am J Ther. 2002 Jan-Feb;9(1

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2011 The Journal of Pediatric Pharmacology and Therapeutics : JPPT

79. Meperidine Restriction in a Pediatric Hospital (PubMed)

Meperidine Restriction in a Pediatric Hospital Much has been published revealing concerns surrounding the use of meperidine due to associated toxicities, drug interactions, and lack of proven efficacy. Thus, many adult institutions have chosen to remove or limit the use of this agent, while little has been published about the restriction of meperidine in pediatrics. Many clinicians feel there are still clinical situations in which this agent may be useful.To describe methods taken (...) in a pediatric hospital to restrict the use of meperidine and review literature describing uses of meperidine as a second-line agent.In our pediatric institution, a policy to restrict the use of meperidine was developed, approved, and implemented. An assessment of meperidine's use 6 months prior to policy implementation was done, along with a postinitiation review of use.Data revealed that the use of meperidine dropped from 646 doses in 84 patients to 226 doses in 27 patients after restriction

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2011 The Journal of Pediatric Pharmacology and Therapeutics : JPPT

80. Combining intrathecal bupivacaine and meperidine during caesarean section to prevent spinal anaesthesia-induced hypotension and other side-effects. (PubMed)

Combining intrathecal bupivacaine and meperidine during caesarean section to prevent spinal anaesthesia-induced hypotension and other side-effects. This study compared intrathecal hyperbaric bupivacaine with low-dose intrathecal plain bupivacaine plus different doses of meperidine (pethidine), administered sequentially, with regard to blood pressure stability, post-operative analgesia and incidence of side-effects in 80 parturients undergoing caesarean section. Patients were randomly assigned (...) to one of four groups (n=20 each group): the HB group received 10 mg hyperbaric bupivacaine intrathecally; the BM35, BM30 and BM25 groups received 5 mg plain bupivacaine plus 35, 30 or 25 mg of meperidine intrathecally, respectively. The incidence of hypotension in the BM25 group was significantly lower than in the HB group. Nausea and vomiting were less prevalent in the BM25 group than in the HB and BM35 groups. In conclusion, sequential administration of 5 mg plain bupivacaine and 25 mg meperidine

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2011 The Journal of international medical research

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