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Meperidine

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61. Intrathecal Meperidine Plus Lidocaine for Prevention of Shivering during Cesarean Section. (Full text)

Intrathecal Meperidine Plus Lidocaine for Prevention of Shivering during Cesarean Section. Shivering related to spinal anesthesia may interfere with monitoring and is uncomfortable. The aim of the present study was to investigate low-dose intrathecal meperidine for the prevention of shivering after induction of spinal anesthesia in parturients with cesarean section.This was a prospective randomized, double-blind, placebo-controlled trial including 100 parturients, of American Society (...) of Anesthesiologists (ASA) physical status I or II, scheduled for elective cesarean section under spinal anesthesia who were randomly assigned to a meperidine (0.2 mg/kg) plus hyperbaric lidocaine (5%, 75 mg, n = 50; group M) group or a placebo plus hyperbaric lidocaine (5%, 75 mg, n = 50; group L) group. Demographic and surgical data, adverse events, and the mean intensity for each parturient were assessed during the entire study period by a blinded observer.There were no significant differences between the two

2013 The Korean journal of pain Controlled trial quality: predicted high

62. Two dosages of remifentanil for patient-controlled analgesia vs. meperidine during colonoscopy: A prospective randomized controlled trial. (PubMed)

Two dosages of remifentanil for patient-controlled analgesia vs. meperidine during colonoscopy: A prospective randomized controlled trial. BACKGROUND AND STUDY: Combined use of opiates and benzodiazepines often results in delayed discharge after colonoscopy.To compare sedation quality of two dosages of patient controlled analgesia remifentanil with one another and with that of a midazolam-meperidine association during colonoscopy.Ninety patients undergoing colonoscopy were randomly assigned (...) to three groups. Group M received a meperidine bolus (0.7 mg/kg) and sham patient controlled analgesia. Group R1 received remifentanil 0.5 μg/kg and group R2 remifentanil 0.8 μg/kg together with a patient-controlled analgesia pump injecting further boluses (2-min lock-out). Technical difficulties of the examination, gastroenterologist's and patient's satisfaction with sedoanalgesia were evaluated after colonoscopy on a 100 mm Visual Analogue Scale. Patient's satisfaction was assessed 24 h later.Group M

2013 Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver Controlled trial quality: uncertain

63. Meperidine for Patients Expected to Have Poor Tolerance During Diagnostic Esophagogastroduodenoscopy.

Meperidine for Patients Expected to Have Poor Tolerance During Diagnostic Esophagogastroduodenoscopy. Meperidine for Patients Expected to Have Poor Tolerance During Diagnostic Esophagogastroduodenoscopy. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Meperidine for Patients Expected to Have Poor Tolerance During Diagnostic Esophagogastroduodenoscopy. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01948921 Recruitment Status : Completed First Posted : September 24, 2013 Last Update Posted : March 20

2013 Clinical Trials

64. Meperidine: A Continuing Problem (Full text)

Meperidine: A Continuing Problem Letter to the Editor regarding meperidine prescriptions in Queensland, Australia, 1999 to 2010.

2013 Substance Abuse: Research and Treatment

65. Analgesic Efficacy of Diclofenac and Paracetamol vs. Meperidine in Cesarean Section (Full text)

Analgesic Efficacy of Diclofenac and Paracetamol vs. Meperidine in Cesarean Section One of the most important complications in cesarean surgery is postoperative pain, and different ways have been proposed to control it.The purpose of this study was to determine the efficacy of Diclofenac and Paracetamol combination in comparison with Meperidine on postoperative pain after cesarean surgery.One hundred and twenty women candidates for elective cesarean section under spinal anesthesia categorized (...) as ASA class I were selected and randomly assigned to receive either Diclofenac suppository at the end of the operation and thereafter 1 gram infused bolus of Paracetamol (group A), or 20 mg bolus of Meperidine after transition to recovery room (group B) to control postoperative pain.Postoperative pain was present in recovery in 38.3% and 23.3% in groups B and A, respectively (P = 0.009). Postoperative pain was seen after six hours of operation in 38.7% and 16.7% in groups B and A, respectively (P

2013 Anesthesiology and pain medicine Controlled trial quality: uncertain

66. Meperidine

Meperidine Meperidine Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Meperidine Meperidine Aka: Meperidine , Demerol From Related (...) over intramuscular No dosing adjustment needed for IV versus IM Dosing frequency is often dosed too infrequently Duration of action is only 3 hours Avoid more than 2-3 doses due to accumulation Often administered with ( ) 25 to 50 mg (0.5 mg/kg) IM q4-6 hours no longer routinely recommended Does not potentiate Meperidine requires intramuscular dosing (sclerosing) Only indicated for Meperidine induced (20%) Consider alternative intravenous Example: Dose only as needed for or VI. Disadvantages Toxic

2015 FP Notebook

67. The Effect of Different Intrathecal Doses of Meperidine on Shivering during Delivery Under Spinal Anesthesia. (PubMed)

The Effect of Different Intrathecal Doses of Meperidine on Shivering during Delivery Under Spinal Anesthesia. This study was performed to compare the effect of different doses of intrathecal meperidine on the incidence and intensity of shivering and other side-effects after spinal anesthesia for cesarean delivery.One hundred and fifty-six parturient women scheduled for elective cesarean delivery were enrolled in four groups. Spinal anesthesia consisted of heavy bupivacaine 0.5% (10 mg (...) ) in the standard group (Group I), heavy bupivacaine 0.5% (10 mg) plus meperidine (0.2 mg per kg) in Group II, heavy bupivacaine 0.5% (10 mg) plus meperidine (0.3 mg per kg) in Group III, heavy bupivacaine 0.5% (10 mg) plus meperidine (0.4 mg per kg) in Group IV. The signs and symptoms were recorded by an observer unaware of the study groups. Data were analyzed using analysis of variance, Kruskal-Wallis H-test and chi-square. A P value less than 0.05 was considered to be significant.The systolic blood pressure

2012 International journal of preventive medicine Controlled trial quality: uncertain

68. A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering: Retraction. (PubMed)

A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering: Retraction. 21451076 2012 07 13 2019 02 25 1526-7598 112 5 2011 May Anesthesia and analgesia Anesth. Analg. A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering: Retraction. 1225 10.1213/ANE.0b013e31821a97f0 eng Retraction of Publication 2011 03 30 United States Anesth Analg 1310650 0003-2999 Piper SN, Maleck WH, Boldt J, Suttner SW, Schmidt CC, Reich

2012 Anesthesia and Analgesia Controlled trial quality: uncertain

69. Comparison of meperidine versus hyoscine during colonoscopy in the elderly: a prospective randomized study. (PubMed)

Comparison of meperidine versus hyoscine during colonoscopy in the elderly: a prospective randomized study. Colonoscopy is the gold standard in diagnosis of diseases of the colon. Sedation and antispasmodic agents are recommended during colonoscopy. Age is a limiting factor when the surgeon is deciding whether to use these medications or not.One hundred twenty patients older than 65 years of age were randomized into two groups. The first group (n=60) received 2 mg of midazolam and 25 mg (...) of meperidine intravenously. The second group (n=60) received 2 mg of midazolam and 20 mg of hyoscine N-butylbromide intravenously. The data collected were colonoscopy procedure time, time to cecum, visual analog pain scale, systolic blood pressure before and after the procedure, pulse, partial oxygen pressure, comfort of the endoscopist, the modified observer's assessment of alertness/sedation scale, and morbidity.Total colonoscopy and cecal reach times were shorter in Group 2 (19.58±4.82 minutes and 10.57

2012 Journal of laparoendoscopic & advanced surgical techniques. Part A Controlled trial quality: uncertain

70. Meperidine for uterine dystocia and its effect on duration of labor and neonatal acid-base status: a randomized clinical trial. (PubMed)

Meperidine for uterine dystocia and its effect on duration of labor and neonatal acid-base status: a randomized clinical trial. The aim of this study was to evaluate the effectiveness of meperidine, administered during the first stage of labor in patients with uterine dystocia, on the duration of labor and neonatal acid-base status at birth.We randomly assigned 240 nulliparous women with a singleton pregnancy at term who were diagnosed with uterine dystocia in labor at 4-6-cm cervical (...) dilatation to receive either a single dose of 50 mg meperidine in 10 mL of saline (slow intravenous injection over 2 min) or 10 mL of isotonic saline (control group). The primary outcome measures were duration of labor (from the time of beginning of the intervention to the time of the expulsion of the fetal head) and umbilical cord arterial acid-base status.The evidence revealed no statistically significant difference between the two groups in length of labor (188.2 ± 92.3 min in the meperidine group

2012 The journal of obstetrics and gynaecology research Controlled trial quality: uncertain

71. The effects of Adding Meperidine to Heavy Intrathecal Lidocaine on Hemodynamic Changes and Blood Loss in Open Prostatectomy: A Randomized Double-Blind Clinical Trial. (Full text)

The effects of Adding Meperidine to Heavy Intrathecal Lidocaine on Hemodynamic Changes and Blood Loss in Open Prostatectomy: A Randomized Double-Blind Clinical Trial. Clinical investigations have reported several anesthetic properties of intrathecal injections of meperidine. The purpose of this study was to investigate the effect of adding meperidine to intrathecal heavy lidocaine on hemodynamic changes and blood loss in patients undergoing elective suprapubic open prostatectomy.In a randomized (...) double-blind clinical trial, 77 patients candidate for elective suprapubic open prostatectomy were allocated to two equal groups. All patients in the control and experimental groups received heavy lidocaine intrathecally. A low dose of meperidine was added to lidocaine in the experiment group. Changes in blood pressure and heart rate were measured and documented in several intervals. Blood loss, transfusion rate, shivering, nausea, vomiting, need to an analgesic drug, and transient neurologic

2012 Iranian journal of medical sciences Controlled trial quality: uncertain

72. Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine.

Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. (ERCP) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01709422 Recruitment Status : Completed First Posted : October 18, 2012 Results First Posted : August 27, 2013 Last Update

2012 Clinical Trials

73. A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus

A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01741259 Recruitment Status : Completed First Posted : December 4, 2012 Results First Posted : October 25, 2017 Last Update Posted : October 25

2012 Clinical Trials

74. Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy

Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy (remifentanil) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01693185 Recruitment Status : Completed First Posted : September 26, 2012 Results First Posted : June 18, 2014 Last Update Posted : June 18, 2014 Sponsor: Konkuk

2012 Clinical Trials

75. Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women

Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01555671 Recruitment Status : Completed First Posted : March 15, 2012 Last Update Posted

2012 Clinical Trials

76. Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy

Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Meperidine (...) Chi General Hospital Study Details Study Description Go to Brief Summary: Upper endoscopy is uncomfortable for most patients. Meperidine has both sedative and analgesic effects, so its use may be helpful for patients receiving upper endoscopy. Condition or disease Intervention/treatment Phase Esophagogastroduodenoscopy Drug: Meperidine Drug: normal saline Not Applicable Detailed Description: Unsedated esophagogastroduodenoscopy (EGD) is a useful tool for upper gastrointestinal tract examination

2012 Clinical Trials

77. Intraperitoneal ropivacaine or ropivacaine plus meperidine for laparoscopic gynecological procedures. (Full text)

Intraperitoneal ropivacaine or ropivacaine plus meperidine for laparoscopic gynecological procedures. Postoperative pain after laparoscopic surgery is less intense than after laparotomy and patients may benefit from an intraperitoneal injection of local anesthetic and opioids. We aimed to compare intraperitoneal 0.75% ropivacaine with 0.75% ropivacaine plus meperidine for postoperative analgesia in patients undergoing gynecologic laparoscopy.At the end of gynecologic laparoscopy, in a double (...) -blind, randomized manner, one of the following injections was given intraperitoneally. Patients were allocated into three groups: Patients in R Group (n=18) were given 0.75% ropivacaine 3 mg/kg in 200 mL saline; patients in RM Group (n=17) were given meperidine 50 mg plus 0.75% ropivacaine 3 mg/kg in 200 mL saline; patients in C Group (n=18) were given 200 mL saline through the trocars. All patients were given diclofenac sodium when they had pain (VAS 3) and 1 mg/kg meperidine i.v. was also given

2012 Aǧrı : Ağrı (Algoloji) Derneği'nin Yayın organıdır = The journal of the Turkish Society of Algology

78. Double-blind comparison of butorphanol and meperidine in the treatment of post-surgical pain. (PubMed)

Double-blind comparison of butorphanol and meperidine in the treatment of post-surgical pain. 357232 1978 11 18 2017 02 14 0300-0605 6 4 1978 The Journal of international medical research J. Int. Med. Res. Double-blind comparison of butorphanol and meperidine in the treatment of post-surgical pain. 306-11 Stehling L C LC Zauder H L HL eng Clinical Trial Comparative Study Controlled Clinical Trial Journal Article Randomized Controlled Trial England J Int Med Res 0346411 0300-0605 0 Morphinans (...) 9E338QE28F Meperidine QV897JC36D Butorphanol IM Butorphanol adverse effects therapeutic use Clinical Trials as Topic Double-Blind Method Humans Meperidine adverse effects therapeutic use Morphinans therapeutic use Pain, Postoperative drug therapy 1978 1 1 1978 1 1 0 1 1978 1 1 0 0 ppublish 357232 10.1177/030006057800600408

1978 The Journal of international medical research Controlled trial quality: uncertain

79. Meperidine Idiosyncrasy (Full text)

Meperidine Idiosyncrasy 19599069 2009 07 30 2009 07 30 12 9 1965 Nov Journal of the American Dental Society of Anesthesiology J Am Dent Soc Anesthesiol Meperidine Idiosyncrasy. 286 eng Journal Article United States J Am Dent Soc Anesthesiol 7505572 2009 7 15 9 0 1965 11 1 0 0 1965 11 1 0 1 ppublish 19599069 PMC2033287

1965 Journal of the American Dental Society of Anesthesiology

80. Two mechanisms for the meperidine block of action potential production in frog's skeletal muscle; non-specific and opiate drug receptor mediated blockade. (Full text)

Two mechanisms for the meperidine block of action potential production in frog's skeletal muscle; non-specific and opiate drug receptor mediated blockade. The effects of meperidine and naloxone, and their interaction effects on action potential production in frog's sartorius muscle fibres, were studied with intracellular micro-electrode techniques. 1. Meperidine, a narcotic analgesic drug, depressed the rate of rise, the rate of fall and the amplitude of the action potentials. 2 (...) . At a meperidine concentration of 0-35 mM, the depression in the action potential maximum rate of rise followed a diphasic time course. At first there was a rapid reduction in the maximum rate of rise which was levelling off at about 60% of control 60-90 min after drug application. This was followed by the second phase during which there was an initial rapid decrease in the maximum rate of rise and all surface fibres were inexcitable by 180 min. 3. The addition of naloxone, a narcotic antagonist, in low

1975 The Journal of physiology

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