How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,596 results for

Meperidine

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

61. Impact of fentanyl in lieu of meperidine on endoscopy unit efficiency: a prospective comparative study in patients undergoing EGD. (Abstract)

Impact of fentanyl in lieu of meperidine on endoscopy unit efficiency: a prospective comparative study in patients undergoing EGD. Turnaround time is an important component of endoscopy unit efficiency. Any reduction in the total time from patient arrival in the endoscopy room to departure from the recovery area may translate into better endoscopy unit efficiency.To evaluate the effects on endoscopy unit efficiency of a change in narcotic choice for moderate sedation in patients undergoing EGD (...) was associated with reduced total procedure time by 10.1 minutes resulting from both shorter induction-to-intubation time and extubation-to-discharge time (P < .001). The mean (± SD) sedation-dependent endoscopy unit efficiency was 3.2 (± 1.9) procedures per hour for the meperidine group and 3.9 (± 2.7) procedures per hour for the fentanyl group (P = .012); this would translate into possibly increasing the endoscopy suite efficiency by 22%. Based on dosage equivalency conversion, equal doses of fentanyl

2013 Gastrointestinal endoscopy

62. Two dosages of remifentanil for patient-controlled analgesia vs. meperidine during colonoscopy: A prospective randomized controlled trial. (Abstract)

Two dosages of remifentanil for patient-controlled analgesia vs. meperidine during colonoscopy: A prospective randomized controlled trial. BACKGROUND AND STUDY: Combined use of opiates and benzodiazepines often results in delayed discharge after colonoscopy.To compare sedation quality of two dosages of patient controlled analgesia remifentanil with one another and with that of a midazolam-meperidine association during colonoscopy.Ninety patients undergoing colonoscopy were randomly assigned (...) to three groups. Group M received a meperidine bolus (0.7 mg/kg) and sham patient controlled analgesia. Group R1 received remifentanil 0.5 μg/kg and group R2 remifentanil 0.8 μg/kg together with a patient-controlled analgesia pump injecting further boluses (2-min lock-out). Technical difficulties of the examination, gastroenterologist's and patient's satisfaction with sedoanalgesia were evaluated after colonoscopy on a 100 mm Visual Analogue Scale. Patient's satisfaction was assessed 24 h later.Group M

2013 Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver Controlled trial quality: uncertain

63. Meperidine as the single sedative agent during esophagogastroduodenoscopy, a double-blind, randomized controlled study. (Abstract)

Meperidine as the single sedative agent during esophagogastroduodenoscopy, a double-blind, randomized controlled study. In Taiwan, unsedated esophagogastroduodenoscopy (EGD) is widely used, but it is uncomfortable for some patients. While meperidine has been adopted in colonoscopy, its use in EGD has not received extensive attention. This was a prospective study to investigate the use of meperidine as a single sedative agent during EGD.One hundred and forty patients were randomized to receive (...) either 25-mg meperidine (n = 70) or placebo (n = 70) by intramuscular injection before EGD. The primary outcome was patient discomfort scores. The secondary outcomes included patient, endoscopist, and EGD-related variables.Patients in the meperidine group reported less discomfort during esophageal intubation (median score of 2.0 and interquartile range [IQR] of 0-4.0 vs median score of 4.8 and IQR of 1.7-7.0, respectively; P < 0.001) and during the procedure (median score of 1.0 [IQR 0-3.1] vs 3.5

2013 Journal of gastroenterology and hepatology Controlled trial quality: predicted high

64. Comparison of the Analgesic Efficacy of Dexketoprofen Trometamol and Meperidine HCl in the Relief of Renal Colic. (Abstract)

Comparison of the Analgesic Efficacy of Dexketoprofen Trometamol and Meperidine HCl in the Relief of Renal Colic. In this study, the analgesic effects of dexketoprofen trometamol and meperidine hydrochloride were compared in patients diagnosed with renal colic. This study was a prospective, randomized, double-blind study. Fifty-two patients, between the ages of 18 and 70 years who were diagnosed with renal colic, were enrolled in the study after obtaining ethics committee approval. Before drug (...) injection, dexketoprofen trometamol and meperidine hydrochloride were placed in closed envelopes, and the patients were randomly given a single dose of intravenous infusion for 20 minutes. Severity of pain and symptoms was evaluated with the numerical rating scale and renal colic symptom score for each patient immediately before administration of drugs and 30 minutes after the end of the application. At the same time, systolic arterial blood pressure, diastolic arterial pressure, respiratory rate, heart

2013 American journal of therapeutics Controlled trial quality: uncertain

65. Comparison of effects of epidural bupivacaine and intravenous meperidine analgesia on patient recovery following elective abdominal aortic surgery. Full Text available with Trip Pro

Comparison of effects of epidural bupivacaine and intravenous meperidine analgesia on patient recovery following elective abdominal aortic surgery. The efficacy of epidural anesthesia and analgesia in management of perioperative stress has been established. Perioperative pain management strategies decrease surgical complications and aid recovery. In this study, we aimed to document and compare the efficacy of epidural bupivacaine and intravenous meperidine on recovery of patients with elective (...) abdominal aortic surgery performed under general anesthesia.Patients undergoing elective abdominal aortic surgery between February 2009 and November 2011 were studied prospectively. Patients were randomized into epidural bupivacaine (n=40) and intravenous meperidine (n=40) groups regarding postoperative analgesia strategy. The preoperative demographic characteristics, perioperative outcomes, postoperative adverse effects of analgesia strategy, time to initiate oral intake, sedation scores, visual

2013 Medical science monitor : international medical journal of experimental and clinical research Controlled trial quality: uncertain

66. Meperidine

Meperidine Meperidine Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Meperidine Meperidine Aka: Meperidine , Demerol From Related (...) over intramuscular No dosing adjustment needed for IV versus IM Dosing frequency is often dosed too infrequently Duration of action is only 3 hours Avoid more than 2-3 doses due to accumulation Often administered with ( ) 25 to 50 mg (0.5 mg/kg) IM q4-6 hours no longer routinely recommended Does not potentiate Meperidine requires intramuscular dosing (sclerosing) Only indicated for Meperidine induced (20%) Consider alternative intravenous Example: Dose only as needed for or VI. Disadvantages Toxic

2015 FP Notebook

67. A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering: Retraction. (Abstract)

A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering: Retraction. 21451076 2012 07 13 2019 02 25 1526-7598 112 5 2011 May Anesthesia and analgesia Anesth. Analg. A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering: Retraction. 1225 10.1213/ANE.0b013e31821a97f0 eng Retraction of Publication 2011 03 30 United States Anesth Analg 1310650 0003-2999 Piper SN, Maleck WH, Boldt J, Suttner SW, Schmidt CC, Reich

2012 Anesthesia and Analgesia Controlled trial quality: uncertain

68. The Effect of Different Intrathecal Doses of Meperidine on Shivering during Delivery Under Spinal Anesthesia. (Abstract)

The Effect of Different Intrathecal Doses of Meperidine on Shivering during Delivery Under Spinal Anesthesia. This study was performed to compare the effect of different doses of intrathecal meperidine on the incidence and intensity of shivering and other side-effects after spinal anesthesia for cesarean delivery.One hundred and fifty-six parturient women scheduled for elective cesarean delivery were enrolled in four groups. Spinal anesthesia consisted of heavy bupivacaine 0.5% (10 mg (...) ) in the standard group (Group I), heavy bupivacaine 0.5% (10 mg) plus meperidine (0.2 mg per kg) in Group II, heavy bupivacaine 0.5% (10 mg) plus meperidine (0.3 mg per kg) in Group III, heavy bupivacaine 0.5% (10 mg) plus meperidine (0.4 mg per kg) in Group IV. The signs and symptoms were recorded by an observer unaware of the study groups. Data were analyzed using analysis of variance, Kruskal-Wallis H-test and chi-square. A P value less than 0.05 was considered to be significant.The systolic blood pressure

2012 International journal of preventive medicine Controlled trial quality: uncertain

69. Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women

Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01555671 Recruitment Status : Completed First Posted : March 15, 2012 Last Update Posted

2012 Clinical Trials

70. Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy

Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Meperidine (...) Chi General Hospital Study Details Study Description Go to Brief Summary: Upper endoscopy is uncomfortable for most patients. Meperidine has both sedative and analgesic effects, so its use may be helpful for patients receiving upper endoscopy. Condition or disease Intervention/treatment Phase Esophagogastroduodenoscopy Drug: Meperidine Drug: normal saline Not Applicable Detailed Description: Unsedated esophagogastroduodenoscopy (EGD) is a useful tool for upper gastrointestinal tract examination

2012 Clinical Trials

71. A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus

A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01741259 Recruitment Status : Completed First Posted : December 4, 2012 Results First Posted : October 25, 2017 Last Update Posted : October 25

2012 Clinical Trials

72. Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine.

Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. (ERCP) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01709422 Recruitment Status : Completed First Posted : October 18, 2012 Results First Posted : August 27, 2013 Last Update

2012 Clinical Trials

73. Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy

Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy (remifentanil) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01693185 Recruitment Status : Completed First Posted : September 26, 2012 Results First Posted : June 18, 2014 Last Update Posted : June 18, 2014 Sponsor: Konkuk

2012 Clinical Trials

74. Comparison of meperidine versus hyoscine during colonoscopy in the elderly: a prospective randomized study. (Abstract)

Comparison of meperidine versus hyoscine during colonoscopy in the elderly: a prospective randomized study. Colonoscopy is the gold standard in diagnosis of diseases of the colon. Sedation and antispasmodic agents are recommended during colonoscopy. Age is a limiting factor when the surgeon is deciding whether to use these medications or not.One hundred twenty patients older than 65 years of age were randomized into two groups. The first group (n=60) received 2 mg of midazolam and 25 mg (...) of meperidine intravenously. The second group (n=60) received 2 mg of midazolam and 20 mg of hyoscine N-butylbromide intravenously. The data collected were colonoscopy procedure time, time to cecum, visual analog pain scale, systolic blood pressure before and after the procedure, pulse, partial oxygen pressure, comfort of the endoscopist, the modified observer's assessment of alertness/sedation scale, and morbidity.Total colonoscopy and cecal reach times were shorter in Group 2 (19.58±4.82 minutes and 10.57

2012 Journal of laparoendoscopic & advanced surgical techniques. Part A Controlled trial quality: uncertain

75. The effects of Adding Meperidine to Heavy Intrathecal Lidocaine on Hemodynamic Changes and Blood Loss in Open Prostatectomy: A Randomized Double-Blind Clinical Trial. Full Text available with Trip Pro

The effects of Adding Meperidine to Heavy Intrathecal Lidocaine on Hemodynamic Changes and Blood Loss in Open Prostatectomy: A Randomized Double-Blind Clinical Trial. Clinical investigations have reported several anesthetic properties of intrathecal injections of meperidine. The purpose of this study was to investigate the effect of adding meperidine to intrathecal heavy lidocaine on hemodynamic changes and blood loss in patients undergoing elective suprapubic open prostatectomy.In a randomized (...) double-blind clinical trial, 77 patients candidate for elective suprapubic open prostatectomy were allocated to two equal groups. All patients in the control and experimental groups received heavy lidocaine intrathecally. A low dose of meperidine was added to lidocaine in the experiment group. Changes in blood pressure and heart rate were measured and documented in several intervals. Blood loss, transfusion rate, shivering, nausea, vomiting, need to an analgesic drug, and transient neurologic

2012 Iranian journal of medical sciences Controlled trial quality: uncertain

76. Meperidine for uterine dystocia and its effect on duration of labor and neonatal acid-base status: a randomized clinical trial. (Abstract)

Meperidine for uterine dystocia and its effect on duration of labor and neonatal acid-base status: a randomized clinical trial. The aim of this study was to evaluate the effectiveness of meperidine, administered during the first stage of labor in patients with uterine dystocia, on the duration of labor and neonatal acid-base status at birth.We randomly assigned 240 nulliparous women with a singleton pregnancy at term who were diagnosed with uterine dystocia in labor at 4-6-cm cervical (...) dilatation to receive either a single dose of 50 mg meperidine in 10 mL of saline (slow intravenous injection over 2 min) or 10 mL of isotonic saline (control group). The primary outcome measures were duration of labor (from the time of beginning of the intervention to the time of the expulsion of the fetal head) and umbilical cord arterial acid-base status.The evidence revealed no statistically significant difference between the two groups in length of labor (188.2 ± 92.3 min in the meperidine group

2012 The journal of obstetrics and gynaecology research Controlled trial quality: uncertain

77. Double-blind comparison of butorphanol and meperidine in the treatment of post-surgical pain. (Abstract)

Double-blind comparison of butorphanol and meperidine in the treatment of post-surgical pain. 357232 1978 11 18 2017 02 14 0300-0605 6 4 1978 The Journal of international medical research J. Int. Med. Res. Double-blind comparison of butorphanol and meperidine in the treatment of post-surgical pain. 306-11 Stehling L C LC Zauder H L HL eng Clinical Trial Comparative Study Controlled Clinical Trial Journal Article Randomized Controlled Trial England J Int Med Res 0346411 0300-0605 0 Morphinans (...) 9E338QE28F Meperidine QV897JC36D Butorphanol IM Butorphanol adverse effects therapeutic use Clinical Trials as Topic Double-Blind Method Humans Meperidine adverse effects therapeutic use Morphinans therapeutic use Pain, Postoperative drug therapy 1978 1 1 1978 1 1 0 1 1978 1 1 0 0 ppublish 357232 10.1177/030006057800600408

1978 The Journal of international medical research Controlled trial quality: uncertain

78. Letter: Psychotic symptoms due to meperidine intoxication. Full Text available with Trip Pro

Letter: Psychotic symptoms due to meperidine intoxication. 4834427 1974 08 23 2013 11 21 0008-4409 110 11 1974 Jun 08 Canadian Medical Association journal Can Med Assoc J Letter: Psychotic symptoms due to meperidine intoxication. 1237 MacVicar A A AA eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 9E338QE28F Meperidine U42B7VYA4P Chlorpromazine AIM IM Adult Aged Chlorpromazine therapeutic use Humans Meperidine adverse effects Middle Aged Psychoses, Substance-Induced drug therapy

1974 Canadian Medical Association Journal

79. Two mechanisms for the meperidine block of action potential production in frog's skeletal muscle; non-specific and opiate drug receptor mediated blockade. Full Text available with Trip Pro

Two mechanisms for the meperidine block of action potential production in frog's skeletal muscle; non-specific and opiate drug receptor mediated blockade. The effects of meperidine and naloxone, and their interaction effects on action potential production in frog's sartorius muscle fibres, were studied with intracellular micro-electrode techniques. 1. Meperidine, a narcotic analgesic drug, depressed the rate of rise, the rate of fall and the amplitude of the action potentials. 2 (...) . At a meperidine concentration of 0-35 mM, the depression in the action potential maximum rate of rise followed a diphasic time course. At first there was a rapid reduction in the maximum rate of rise which was levelling off at about 60% of control 60-90 min after drug application. This was followed by the second phase during which there was an initial rapid decrease in the maximum rate of rise and all surface fibres were inexcitable by 180 min. 3. The addition of naloxone, a narcotic antagonist, in low

1975 The Journal of physiology

80. Paradoxical reaction to intravenous pentobarbital, meperidine and scopolamine. Full Text available with Trip Pro

Paradoxical reaction to intravenous pentobarbital, meperidine and scopolamine. 4525975 1974 09 03 2018 11 30 0003-3006 21 3 1974 May-Jun Anesthesia progress Anesth Prog Paradoxical reaction to intravenous pentobarbital, meperidine and scopolamine. 82-3 Hayden J J Jr Byrd B C BC Bunch F L FL eng Journal Article United States Anesth Prog 0043533 0003-3006 9E338QE28F Meperidine DL48G20X8X Scopolamine I4744080IR Pentobarbital K50XQU1029 Nitrous Oxide D Analgesia Injections, Intravenous Meperidine

1974 Anesthesia progress

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>