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Meperidine

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184. Safety and efficacy of therapeutic hypothermia for acute ischemic stroke. Systematic review and Meta-analysis

Chinese medicine (difference in NIHSS score at 24 hours -4 ±0.6 and -1.5±0.4 respectively). However, on the other study the neurological outcome was more favourable in the group treated with thrombolysis alone (difference in NIHSS score at 24 hours (+3 versus -2.5 respectively) possibly due to the sedative action of meperidine used in the intervention group. Among the parameters related to patient morbidity, differences were found with respect to high dose and duration of norepinephirne in patients

2014 Health Technology Assessment (HTA) Database.

185. Safe and effective procedural sedation for gastrointestinal endoscopy in children Full Text available with Trip Pro

found that propofol was associated with significantly higher levels of effectiveness and patient comfort, with fewer adverse events when compared with midazolam and meperidine. One RCT found that ketamine premedication and propofol were significantly more effective in reducing propofol infusion pain than lidocaine-propofol mixture without premedication. Opioid and benzodiazepine-based sedation (three RCTs): In all of the opioid plus benzodiazepine-based regimens, the incidence of major respiratory (...) complications was 0.2%. One RCT found that use of meperidine and midazolam compared with propofol, with or without premedication midazolam, was associated with significantly higher need for supplemental oxygen, equally high procedural success rate, but it took a significantly longer time to achieve adequate sedation, mean procedure time and recovery time. One RCT reported that fentanyl plus midazolam and meperidine plus midazolam were equally safe and effective. One RCT found that intravenous meperidine

2012 DARE.

186. Watchful Dosing of Morphine or Morphine Equivalent Dosing in the Treatment of Chronic Non-Cancer Pain: A Review of the Clinical Evidence

Dosing 10 Appendix 2: Summary of Study Characteristics First Author, Publication Year, Country Study Design Population Intervention Comparator Outcomes Gomes, 2011a, Canada 7 Population- based nested case-control study Ontario Drug Benefit Program beneficiaries aged 15-64 years old who received >1 opioid prescription (i.e., codeine, morphine, oxycodone, hydromorphone, meperidine, transdermal fentanyl) for chronic non- cancer-related pain. >1 opioid prescription(s) (i.e., codeine, morphine, oxycodone (...) , hydromorphone, meperidine, transdermal fentanyl) for chronic non-cancer-related pain over the course of the study period (August 1, 1997 to December 31, 2006) Five categories of mean daily morphine equivalent dosing: 200 mg Opioid-related mortality Gomes, 2011b, Canada 8 Cross-sectional time series analysis followed by exploratory analysis Ontario Drug Benefit Program beneficiaries aged 15-64 years old who received >1 opioid prescription (i.e., codeine, morphine, oxycodone, hydromorphone, meperidine

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

188. Comparison of the Post-Caesarean Analgesic Effect of Adding Dexmedetomidine to Paracetamol and Ketorolac: A Randomized Clinical Trial. Full Text available with Trip Pro

scale, hemodynamic changes, rescue analgesic (meperidine) consumption, patient satisfaction, and possible complications were recorded at 6, 12, and 24, hours after surgery, and compared afterward.The pain score was significantly lower in the DK group than in the DP group (P < 0.05). The hemodynamics and sedation scale were similar in both groups. The total meperidine consumption was higher in the DP group, but it was not significantly different. Maternal satisfaction was greater in the DK group (P

2018 Anesthesiology and pain medicine Controlled trial quality: uncertain

189. The effect of rectus muscle re-approximation at cesarean delivery on pain perceived after operation: a randomized control trial. (Abstract)

complication were also assessed.Postoperative pain score at the end of the first 24 hours and at the end of the next 24 hours were significantly higher among the group of rectus muscle reapproximation (a difference in VAS pain score of: 5, 95% confidence interval: 0.1-11, p value: .02) and (a difference of 1, 95% confidence interval: 0.1-2.9, p value: .01), respectively. As regards the narcotic use in the first 24 hours after cesarean section, in the form of injections of meperidine 50 mg

2018 The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Controlled trial quality: predicted high

190. [Effect of continuous and single shot adductor canal blocks for postoperative analgesia and early rehabilitation after total knee arthroplasty]. (Abstract)

patients in group A and 7 patients in group B requiring meperidine hydrochloride (50 mg/time) within 24 hours, and 3 patients in group A and 7 patients in group B at 24 to 48 hours, and 1 patient in group A and 3 patients in group B at 48 to 72 hours. Effusion in the catheter site occurred in 2 cases of group A, but no catheter extrusion occurred.Continuous ACB is superior in analgesia both at rest and during activity and opioid consumption compared with single shot ACB after TKA. And the quadriceps

2018 Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery Controlled trial quality: uncertain

191. Topical Transdermally Delivered Lidocaine and Benzocaine Compared to Compounded Lidocaine/Tetracaine During Microfocused Ultrasound With Visualization Treatment. (Abstract)

%/tetracaine 7% (23/7) to mitigate discomfort during MFU-V treatment.This was a randomized, double-blinded, split-face study. One hour before MFU-V, subjects (N=14 females) received 50 mg IM meperidine/25 mg IM promethazine/5 mg oral diazepam. Fifteen minutes before treatment, 1 side of the face was treated with 1 application of 4% lidocaine, followed by 1 application of 20% benzocaine; the contralateral side was treated with 2 applications of 23/7 (to maintain blinding). Numbness was assessed by blinded

2018 Journal of drugs in dermatology : JDD Controlled trial quality: uncertain

192. Evaluation of hyoscine N-butyl bromide efficacy on the prevention of catheter-related bladder discomfort after transurethral resection of prostate: a randomized, double-blind control trial. (Abstract)

, statistically significant less CRBD was seen in the treatment group comparing to the control group (P ≤ 0.05 and P ≤ 0.007). The total utilized meperidine dose during PACU stay and the time to discharge for the intervention group were significantly lower than those for the control group (P ≤ 0.0001) with no significant difference in adverse effects (P > 0.05).Hyoscine N-butyl bromide could reduce the severity of CRBD related to TURP in patients with BPH and their need for analgesic consumption either

2018 International urology and nephrology Controlled trial quality: uncertain

193. Lumbar Erector Spinae Plane Block and Quadratus Lumborum Block in Hip and Proximal Femur Surgeries

of erector spinae muscle. The location of the needle tip will be confirmed by visible fluid spread lifting erector spinae muscle off the bony shadow of the transverse process. A total of 40 mL of bupivacaine/lidocaine mixture will be injected. Other: Standard Pain Followup and Monitorization Numeric Rating Scale (NRS) pain score will be recorded from 20th minute in recovery room followed by 1.-3.-6.-12.-18.-24.hours. Intravenous meperidine administration at 0.5 mg / kg rescue analgesia was determined (...) in patients with a NSR score of 6 and over in the postoperative collection room. It is planned that the patient will continue to follow the hourly NRS score in ward. Intramuscular diclofenac will be administered in this period if NRS 6 and if it is over, intravenous 0.5 mg / kg meperidine will be administered if NRS score is 6 or more after 2 hours. Salvage analgesic needs and times will be noted in detail, and the use of rescue analgesics, as well as NRS scores at designated hours, will be kept

2018 Clinical Trials

194. Erector Spinae Plane Block and Oblique Subcostal Transverse Abdominis Plane Block in Laparoscopic Cholecystectomy

: Standard Pain Followup and Monitorization Numeric Rating Scale (NRS) pain score will be recorded from 20th minute in recovery room followed by 1.-3.-6.-12.-18.-24.hours. Intravenous meperidine administration at 0.5 mg / kg rescue analgesia was determined in patients with a NSR score of 6 and over in the postoperative collection room. It is planned that the patient will continue to follow the hourly NRS score in ward. Intramuscular diclofenac will be administered in this period if NRS 6 (...) and if it is over, intravenous 0.5 mg / kg meperidine will be administered if NRS score is 6 or more after 2 hours. Salvage analgesic needs and times will be noted in detail, and the use of rescue analgesics, as well as NRS scores at designated hours, will be kept in a statistical evaluation. Active Comparator: OSTAP Block Ultrasound-guided bilateral OSTAP block performed at end of the surgery with 40 ml of a bupivacaine/lidocaine mixture. Perioperative and postoperative routine analgesic protocol

2018 Clinical Trials

195. Erector Spinae Block in Segmental Mastectomy.

the patient will receive tramadol 100mg as rescue analgesia. In case of persisting pain first, meperidine 50 mg will be apllied and other multimodal analgesic drugs will be added to protocol. At the end of the study 24 hours total opioid usage of patients, pain scores and side effects will statistically be analyzed. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 30 participants Allocation: Randomized Intervention Model: Parallel

2018 Clinical Trials

196. Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior Immunotherapy

treatment. Has received prior therapy with an IDO inhibiting agent. Has a known history of Human Immunodeficiency Virus (HIV) (HIV 1/2 antibodies). Has known active Hepatitis B (e.g., HBsAg reactive) or Hepatitis C (e.g., HCV RNA [qualitative] is detected). Has received a live vaccine within 30 days of planned start of study therapy. Has received MAO-inhibitors (MAOI) or drug which has significant MAOI activity (meperidine, linezolid, methylene blue) within the 21 days before screening. History

2018 Clinical Trials

197. Comparison of Transversus Abdominis Plane Block and Erector Spinae Plane Block in Inguinal Hernia Repair

will continue to follow the hourly NRS score in ward. Intramuscular diclofenac will be administered in this period if NRS 4 and if it is over, intravenous 0.5 mg / kg meperidine will be administered if NRS score is 4 or more after 2 hours. Salvage analgesic needs and times will be noted in detail, and the use of rescue analgesics, as well as NRS scores at designated hours, will be kept in a statistical evaluation. Active Comparator: TAP Block Ultrasound-guided Transversus abdominis plane (TAP) block (...) and Monitorization will be performed. Other: Standard Pain Followup and Monitorization Numeric Rating Scale (NRS) pain score will be recorded and followed by 0., 1.-3.-6.-12.-18.-24.hours. it is planned that the patient will continue to follow the hourly NRS score in ward. Intramuscular diclofenac will be administered in this period if NRS 4 and if it is over, intravenous 0.5 mg / kg meperidine will be administered if NRS score is 4 or more after 2 hours. Salvage analgesic needs and times will be noted in detail

2018 Clinical Trials

198. Epacadostat in Combination With Radiation Therapy and Avelumab in Patients With Recurrent Gliomas

or may interfere with the interpretation of study results and, in the judgment of the investigator, would make the patient inappropriate for entry into this study. Has an active infection requiring systemic therapy. Has received prior therapy with an anti-PD-1, anti-PD-L1, anti-PD-L2, or IDO inhibitor. Receiving monoamine oxidase inhibitors (MAOIs) or drug which has significant MAOI activity (meperidine, linezolid, methylene blue) within the 21 days before screening. Use of any UGT1A9 inhibitor from

2018 Clinical Trials

199. Comparison of Procedural Sequences in Same-day Painless Bidirectional Endoscopy With Colonoscopic Water Exchange Method

: Patients who < 18 years old, > 80 years old Without standard colon preparation Allergy to meperidine or propofol With a history of partial colectomy Refusal to provide written informed consent American Society of Anesthesiology (ASA) risk Class 3 or higher Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study

2018 Clinical Trials

200. Bupivacaine Verus Pethidine for Post Cesarean Section Pain Relief

Verified: August 2018 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Labor Pain Pain Neurologic Manifestations Signs and Symptoms Bupivacaine Meperidine Anesthetics, Local Anesthetics Central Nervous System Depressants Physiological Effects of Drugs Sensory System Agents Peripheral Nervous System Agents Analgesics, Opioid Narcotics Analgesics Adjuvants

2018 Clinical Trials

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