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1. Management of genitourinary syndrome of menopause in women with or at high risk for breast cancer: consensus recommendations from The North American Menopause Society and The International Society for the Study of Women’s Sexual Health

Management of genitourinary syndrome of menopause in women with or at high risk for breast cancer: consensus recommendations from The North American Menopause Society and The International Society for the Study of Women’s Sexual Health CONSENSUS RECOMMENDATIONS Managementofgenitourinarysyndromeofmenopauseinwomenwith orathighriskforbreastcancer:consensusrecommendationsfromThe North American Menopause Society and The International Society for the Study of Women’s Sexual Health Stephanie S (...) , CCD, NCMP, IF, FACOG, 14 Shari B. Goldfarb, MD, 15 and Sheryl A. Kingsberg, PhD 16 Abstract TheobjectiveofTheNorthAmericanMenopauseSociety(NAMS)andTheInternationalSocietyfortheStudyof Women’s Sexual Health (ISSWSH) Expert Consensus Panel was to create a point of care algorithm for treating genitourinary syndrome of menopause (GSM) in women with or at high risk for breast cancer. The consensus recommendationswillassisthealthcareprovidersinmanagingGSMwithagoalofimprovingthecareandqualityof life

2019 The North American Menopause Society

2. Menopause

Menopause Menopause - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Menopause Last reviewed: February 2019 Last updated: February 2019 Summary The diagnosis is clinical, based on the absence of menses for 12 months, and does not require further testing for appropriately presenting patients. Oestrogen therapy is an effective treatment for the management of menopausal symptoms including hot flushes, night sweats (...) , and is unlikely to increase the risk of stroke or venous thrombosis above that of non-users. Non-hormonal interventions may help women who have a contraindication to, or cannot tolerate, HT. However, they are less effective than HT in controlling menopausal symptoms. Definition Onset of the menopause is heralded by the cessation of menses for at least 12 consecutive months, without some other reason for amenorrhoea (such as pregnancy, hormone therapy, or other medical condition). No further testing

2019 BMJ Best Practice

3. Accuracy of the Menopause Rating Scale and the Menopause Quality of Life Questionnaire to discriminate menopausal women with anxiety and depression. (PubMed)

Accuracy of the Menopause Rating Scale and the Menopause Quality of Life Questionnaire to discriminate menopausal women with anxiety and depression. The aim of the study was to evaluate the accuracy of the Menopause Rating Scale (MRS) and the Menopause Quality of Life Questionnaire (MENQOL) to discriminate women suffering from anxiety (AD) and depression disorder (DD).A cohort of 416 women aged 45 to 65 years (51.7 ± 3.8) completed the MRS, MENQOL and Hospital Anxiety and Depression Scale (...) ), with a specificity ranging from 86.2% to 99.4% and a positive predictive value varying between 68.6% and 92.6%.The MRS and MENQOL display moderate accuracy in discriminating menopausal women with symptoms of anxiety and depression. The intensity of the symptoms appears to be related to the probability of detecting a probable or definitive disorder.

2019 Menopause

4. Menopause

Menopause Evidence Maps - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Evidence Maps

5. British Menopause Society update on HRT supply shortages

British Menopause Society update on HRT supply shortages British Menopause Society further update on HRT supply shortages | British Menopause Society Search for: News 2019-08-23T12:14:14+01:00 23 August 2019 | In response to the ongoing HRT shortages, the British Menopause Society has produced this further update on the current availability of HRT products. This provides guidance to BMS members and clinical practitioners who may be experiencing difficulties with HRT supplies. There continues (...) . Available. Zumenon® 1mg oestradiol and 2mg oestradiol. Shortage of supplies. Elleste Solo™ MX patches 40mcg transdermal oestradiol. Available. Elleste Solo™ MX patches 80mcg transdermal oestradiol. Available. Mylan’s manufacturing partner continues to experience interruptions in the production of certain strengths of Elleste™, their Hormone Replacement Therapy (HRT). They have informed us that they will continue to provide updates on timing for resolution, as they receive them; to the British Menopause

2019 Royal College of Obstetricians and Gynaecologists

9. Menopause

Menopause Menopause - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Menopause Last reviewed: February 2019 Last updated: February 2019 Summary The diagnosis is clinical, based on the absence of menses for 12 months, and does not require further testing for appropriately presenting patients. Oestrogen therapy is an effective treatment for the management of menopausal symptoms including hot flushes, night sweats (...) , and is unlikely to increase the risk of stroke or venous thrombosis above that of non-users. Non-hormonal interventions may help women who have a contraindication to, or cannot tolerate, HT. However, they are less effective than HT in controlling menopausal symptoms. Definition Onset of the menopause is heralded by the cessation of menses for at least 12 consecutive months, without some other reason for amenorrhoea (such as pregnancy, hormone therapy, or other medical condition). No further testing

2018 BMJ Best Practice

10. Feasibility of different treatments for sleep disturbance in peri-menopause and post-menopause breast cancer patients: a systematic review

Feasibility of different treatments for sleep disturbance in peri-menopause and post-menopause breast cancer patients: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration

2019 PROSPERO

11. Menopause

Menopause CLINICAL PROFESSIONAL RESOURCE Menopause RCN guidance for nurses, midwives and health visitors Endorsed by This publication is supported by industryMENOPAUSE 2 This publication is due for review in November 2020. To provide feedback on its contents or on your experience of using the publication, please email publications.feedback@rcn.org.uk Acknowledgements This new publication is based on, and replaces, previous RCN publications – Women’s Health and the Menopause: RCN Guidance (...) for Nurses, Midwives and Health Visitors (RCN, 2005 and 2014) and Complementary Approaches to Menopausal Symptoms: RCN Guidance for Nurses, Midwives and Health Visitors (RCN, 2006). The RCN Women’s Health Forum would like to thank the menopause project team for the development of this publication: Debra Holloway (project chair), Nurse Consultant Gynaecology, Guy’s and St Thomas’ NHS Foundation Trust and Chair of the RCN Women’s Health Forum Carmel Bagness, RCN Professional Lead Midwifery and Women’s

2018 Royal College of Nursing

12. Abnormal Uterine Bleeding in Pre-Menopausal Women

Abnormal Uterine Bleeding in Pre-Menopausal Women No. 292-Abnormal Uterine Bleeding in Pre-Menopausal Women - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 40, Issue 5, Pages e391–e415 No. 292-Abnormal Uterine Bleeding in Pre-Menopausal Women x Sukhbir Singh , MD Ottawa, ON x Carolyn Best , MD Toronto, ON x Sheila Dunn , MD Toronto, ON x Nicholas Leyland , MD Toronto, ON x Wendy Lynn Wolfman , MD Toronto, ON No 292

2018 Society of Obstetricians and Gynaecologists of Canada

13. Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence

Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence No. 358-Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 40, Issue 4, Pages 503–511 No. 358-Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence x Jens-Erik Walter , MD Montréal, QC x Annick Larochelle (...) , MD Montréal, QC No. 358, April 2018 DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Figures Figure Comparative pre- and post-laser vaginal biopsies. Abstract Objective This technical bulletin reviews the evidence relating to risks and benefits of using intravaginal laser technology in the management of genitourinary syndrome of menopause and stress urinary incontinence. Intended Users Gynaecologists, urogynaecologists, urologists

2018 Society of Obstetricians and Gynaecologists of Canada

14. Menopause

Menopause Top results for menopause - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for menopause The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

15. Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence

Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence No. 358-Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 40, Issue 4, Pages 503–511 No. 358-Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence x Jens-Erik Walter , MD Montréal, QC x Annick Larochelle (...) , MD Montréal, QC No. 358, April 2018 DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Figures Figure Comparative pre- and post-laser vaginal biopsies. Abstract Objective This technical bulletin reviews the evidence relating to risks and benefits of using intravaginal laser technology in the management of genitourinary syndrome of menopause and stress urinary incontinence. Intended Users Gynaecologists, urogynaecologists, urologists

2018 Society of Obstetricians and Gynaecologists of Canada

16. Testosterone replacement in menopause

Testosterone replacement in menopause BRITISH MENOPAUSE SOCIETY T ool for clinicians Information for GPs and other health professionals 1 of 4 1 How much and where does it come from? Testosterone is an important female hormone. Healthy young women produce approximately 100 – 400 mcg per day. This represents three to four times the amount of estrogen produced by the ovaries. Approximately half of endogenous testosterone and precursors are derived from the ovaries e.g. androstenedione and half (...) from the adrenal glands e.g. dehydroepiandrosterone. Some of the effects are direct and some due to peripheral conversion to estrogen by aromatase. Testosterone levels naturally decline throughout a woman’s lifespan. Loss of testosterone is particularly profound after iatrogenic i.e. surgical and medical menopause and premature ovarian insufficiency when testosterone production decreases by more than 50%. 2 What is its role in women? Testosterone contributes to libido, sexual arousal and orgasm

2019 British Menopause Society

17. Menopause and the Workplace Guidance: what to consider

Menopause and the Workplace Guidance: what to consider BRITISH MENOPAUSE SOCIETY T ool for clinicians Information for GPs and other health professionals 1 of 3 Menopause and the workplace guidance: what to consider This factsheet provides a ‘how-to’ guide for employers and relevant staff within organisations that are considering writing their own guidance on the menopause. Introduction • In 2019, there are over 4.3million employed women in the UK aged 45-60. 1 • Given the average age (...) of a women’s menopause is 51 years 2 , a significant number of employed women will be working through their menopausal transition. • The experiences of the menopausal transition varies enormously between women. Some women will have no symptoms but most women will experience at least one symptom. 2 Up to a third of women will experience severe menopausal symptoms that can impact on their quality of life. 3,4 • It is the work context that women report greater difficulty in managing symptoms 5,6 and can feel

2019 British Menopause Society

18. Are vaginal estradiol tablets (Vagifem) effective for genitourinary syndrome of menopause?

Are vaginal estradiol tablets (Vagifem) effective for genitourinary syndrome of menopause? Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,800 family physicians, family medicine residents, and medical students in Alberta. Established over sixty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care (...) research. www.acfp.ca June 10, 2019 Verifying the value of vaginal estradiol tablets Clinical Question: Are vaginal estradiol tablets (Vagifem®) effective for genitourinary syndrome of menopause? Bottom Line: Vaginal estradiol tablets are likely no better than placebo vaginal gel for reducing “most bothersome symptom scores” (mainly dyspareunia). However, compared to placebo vaginal tablets, they reduce symptoms (example: treatment “success” at 12 months in 86% versus 41% placebo). A non-medicated

2019 Tools for Practice

19. Managing Menopause Chapter 7 Ongoing Management of Menopausal Women and Those With Special Considerations

Managing Menopause Chapter 7 Ongoing Management of Menopausal Women and Those With Special Considerations Managing Menopause Chapter 7 Ongoing Management of Menopausal Women and Those With Special Considerations - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 36, Issue 9, Supplement 2, Pages S51–S58 Managing Menopause Chapter 7 Ongoing Management of Menopausal Women and Those With Special Considerations DOI: To view (...) the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Figures Figure 7.1 The Stages of Reproductive Aging Workshop + 10 staging system for reproductive aging in women The goal of this chapter is to give practical tips to health care providers for the management of symptomatic women during and after the menopausal transition, concerning mostly the initiation and follow-up of HT. The reader may refer to previous chapters for more extensive literature review

2014 Society of Obstetricians and Gynaecologists of Canada

20. Managing Menopause Chapter 1 Assessment and Risk Management of Menopausal Women

Managing Menopause Chapter 1 Assessment and Risk Management of Menopausal Women Managing Menopause Chapter 1 Assessment and Risk Management of Menopausal Women - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 36, Issue 9, Supplement 2, Pages S6–S15 Managing Menopause Chapter 1 Assessment and Risk Management of Menopausal Women DOI: To view the full text, please login as a subscribed user or . Click to view the full (...) text on ScienceDirect. Figures Menopause is an important milestone and may be one of the first times a woman seeks medical advice around issues of long-term health promotion and disease prevention. Women typically begin to experience menopausal symptoms between 40 and 58 years of age, spending at least one third of their lives after menopause. 1 The 3 main causes of illness and disability in developed countries for postmenopausal women are CVD, cancer, and osteoporosis-associated fractures. 2

2014 Society of Obstetricians and Gynaecologists of Canada

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