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Medication Causes of Headache

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101. Effect of Soft Tissue Techniques on Headache Impact, Disability, and Quality of Life in Migraine Sufferers: A Pilot Study. (Abstract)

improved only in the experimental group (p < 0.001).Soft tissue techniques based on MTrP therapy and stretching were helpful for improving certain aspects of migraine, such as the impact and disability caused by the headache, and the frequency and intensity of headache; however, when combined with suboccipital soft tissue inhibition, the treatment effect was larger. (...) Effect of Soft Tissue Techniques on Headache Impact, Disability, and Quality of Life in Migraine Sufferers: A Pilot Study. To determine the efficacy of suboccipital inhibitory techniques in people with migraine compared with a control treatment based on myofascial trigger point (MTrP) therapy and stretching.A randomized, double-blind controlled pilot trial was conducted.University research laboratory.Forty-six adults diagnosed with migraine with over 6 months duration.Participants were

2018 Journal of Alternative and Complementary Medicine Controlled trial quality: predicted high

102. Diagnosis and Management of Headache in Older Adults. Full Text available with Trip Pro

Diagnosis and Management of Headache in Older Adults. Headache is a common, disabling neurologic problem in all age groups, including older adults. In older adults, headache is most likely a primary disorder, such as tension-type headache or migraine; however, there is a higher risk of secondary causes, such as giant cell arteritis or intracranial lesions, than in younger adults. Thus, based on the headache history, clinical examination, and presence of headache red flags, a focused diagnostic (...) evaluation is recommended, ranging from blood tests to neuroimaging, depending on the headache characteristics. Regardless of the primary or secondary headache disorder diagnosis, treatment options may be limited in older patients and may need to be tailored to the presence of comorbid medical conditions. The purpose of this review is to provide an update on the management of headache in older adults, from diagnosis to treatment.Copyright © 2017 Mayo Foundation for Medical Education and Research

2018 Mayo Clinic Proceedings

103. Benign Headache Management in the Emergency Department. (Abstract)

inflammatory drugs or acetaminophen. Dexamethasone can be used for the reduction of headache recurrence. If dehydration is present, intravenous fluids should be provided. Diphenhydramine is not recommended for analgesia but may reduce akathisia associated with prochlorperazine. Ketamine, propofol, and nerve blocks demonstrate promise. Triptan agents are also efficacious, provided absence of contraindications. Most patients are appropriate for discharge with pain improvement.A variety of medications (...) Benign Headache Management in the Emergency Department. Headache is a common complaint managed in the emergency department (ED), with emergency physicians focusing on evaluation for life-threatening conditions while treating pain and nausea.This review evaluates the treatment of benign, primary headaches in the ED, with recommendations provided based on the literature.Headaches are a major cause of disability in the United States and a common condition managed in the ED. The primary objectives

2018 Journal of Emergency Medicine

104. Global, regional, and national burden of migraine and tension-type headache, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Full Text available with Trip Pro

multiplied by disability weights (a measure of the relative severity of the disabling consequence of a disease). The burden stemming from medication overuse headache, which was included in earlier iterations of GBD as a separate cause, was subsumed as a sequela of either migraine or tension-type headache. Because no deaths were assigned to headaches as the underlying cause, YLDs equate to disability-adjusted life-years (DALYs). We also analysed results on the basis of the Socio-demographic Index (SDI (...) ), a compound measure of income per capita, education, and fertility.Almost three billion individuals were estimated to have a migraine or tension-type headache in 2016: 1·89 billion (95% uncertainty interval [UI] 1·71-2·10) with tension-type headache and 1·04 billion (95% UI 1·00-1·09) with migraine. However, because migraine had a much higher disability weight than tension-type headache, migraine caused 45·1 million (95% UI 29·0-62·8) and tension-type headache only 7·2 million (95% UI 4·6-10·5) YLDs

2018 Lancet Neurology

105. The Prevalence and Impact of Migraine and Severe Headache in the United States: Figures and Trends From Government Health Studies. Full Text available with Trip Pro

conditions.We searched for the most current publicly available summary statistics from the National Health Interview Survey (NHIS), the National Hospital Ambulatory Medical Care Survey (NHAMCS), and the National Ambulatory Medical Care Survey (NAMCS). We extracted and summarized data from each study over time and as a function of demographic variables.The prevalence and burden of self-reported migraine and severe headache in the US adult population is high, affecting roughly 1 out of every 6 American and 1 (...) are unemployed (21.4%), those with family income less than $35,000 per year (19.9%), and the elderly and disabled (16.4%). Headache is consistently the fourth or fifth most common reason for visits to the emergency department, accounting for roughly 3% of all emergency department visits annually. In reproductive aged women, headache is the third leading cause of emergency department visits.Severe headache and migraine remain important public health problems that are more common and burdensome for women

2018 Headache

106. Nerve blocks in paediatric and adolescent headache disorders. (Abstract)

Nerve blocks in paediatric and adolescent headache disorders. Headaches in children and adolescents are common, causing debilitating symptoms in many. Treatment of headache disorders can be complex and standard lifestyle changes as well as oral medications may offer inadequate relief. The purpose of this article is to review the mechanism of action, efficacy and technique of peripheral nerve blocks (PNBs) and the role they play in treating paediatric headache disorders.Evidence for the use (...) of PNBs in youth is limited. However, available studies show evidence of benefit in both primary and secondary headache disorders. Variability exists in the type of block, medication choice, volume infused and frequency of this treatment. There are no serious side effects associated with PNBs.PNBs are well tolerated and effective as adjunctive therapy for many disabling paediatric headache disorders. The technique can be easily learned by frontline and specialty practitioners. Prospective placebo

2018 Current Opinion in Pediatrics

107. Is Sphenopalatine Ganglion Block Treatment Effective on Postspinal Headaches

. The etiology of the postspinal headache remains unclear. Severeness of the symptoms and amount of the cerebrospinal fluid leakage have been found positive correlating. The cerebrospinal fluid supports brain with it's mass effect. When a leakage of the fluid occurs, support of the brain decreases and pain sensitive structures of the brain gets more sensitive. In this condition 5 th 9th and 10 th cranial nerves, falks cerebelli, tentorium and blood vessels are affected most. Decreased cerebrospinal fluid (...) cerebral and meningeal blood vessels which cause vasodilatation and stimulate nociceptor activation on meninges. Consequently headache is related with sensory cortex. Transnasal SPG block is performed successfully in chronic pain syndromes including migraine, cluster headaches and atypic face pain. Likewise the SPG block is performed in acute treatment of postspinal headache. However gold standard of the treatment is epidural blood patching which is interventional and has many risks. Several studies

2018 Clinical Trials

108. Long Term Outcomes Following a Post Dural Puncture Headache

: Assaf-Harofeh Medical Center Information provided by (Responsible Party): Rabin Medical Center Study Details Study Description Go to Brief Summary: Epidural analgesia is considered a gold standard method for treatment of labor pain. One of the major risks with epidural analgesia is an accidental dural puncture, which leads to a post dural puncture headache. This headache is associated with significant maternal morbidity and can result in severe maternal consequences. Post traumatic stress disorder (...) : Other Study ID Numbers: 0536-17-RMC First Posted: June 8, 2018 Last Update Posted: June 8, 2018 Last Verified: April 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Headache Post-Dural Puncture Headache Pain Neurologic Manifestations Signs and Symptoms Headache Disorders

2018 Clinical Trials

109. SubArachnoid Hemorrhage HEadache Treated by Lumbar Puncture

: University Hospital, Toulouse Information provided by (Responsible Party): University Hospital, Toulouse Study Details Study Description Go to Brief Summary: Headache control is one of the major challenges in patients who suffered an acute aneurysmal subarachnoid hemorrhage (aSAH). Headache affects 90% of the patient and is resistant to the major pain medication. It results from the increased intracranial pressure and the inflammation caused by the accumulation of arterial blood in the subarachnoid space (...) Aneurysmal Subarachnoid Hemorrhage Headache Procedure: Lumbar puncture Not Applicable Detailed Description: After aneurysmal subarachnoid hemorrhage (aSAH) almost 90 % of patients experience a severe headache during their hospital stay. Pain control often requires high doses of opioid drugs and sedation that remain only partially efficacious. In addition, there is to the investigator's knowledge currently no recommendation or consensus on aSAH related headache management. aSAH related headache results

2018 Clinical Trials

110. Medical Training to Achieve Competency in Lifestyle Counseling: An Essential Foundation for Prevention and Treatment of Cardiovascular Diseases and Other Chronic Medical Conditions: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

and prerequisite education for providers. Such a paradigm shift begins with medical education and adequate training. Medical schools have the opportunity to shape global health by incorporating lifestyle medicine as part of future physician preparation to practice medicine in the 21st century. The AHA is committed to supporting the transformation of medical education to achieve this goal. The goal of this scientific statement is to provide guidance in defining fundamentals in medical education and training (...) needed for future physicians to be proficient in lifestyle medicine. This writing group acknowledges that curricular design varies among medical schools and that a “one size fits all” model for lifestyle medical education is not practical or advantageous. This scientific statement focuses on key learning objectives (also referred to as learning outcomes in recent literature) that can be implemented as each medical school deems appropriate. Previous Statements and Recommendations In 2004

2016 American Heart Association

111. The care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies

The care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies Practice Parameter update: The care of the patient with amyotrophic lateral sclerosis: Drug, nutritional, and respiratory therapies (an evidence-based review) | Neurology Advertisement Search for this keyword Main menu User menu Search Search for this keyword The most widely read and highly cited peer-reviewed neurology journal Share October 13, 2009 ; 73 (15) Special Article Practice (...) Parameter update: The care of the patient with amyotrophic lateral sclerosis: Drug, nutritional, and respiratory therapies (an evidence-based review) Report of the Quality Standards Subcommittee of the American Academy of Neurology R. G. Miller , C. E. Jackson , E. J. Kasarskis , J. D. England , D. Forshew , W. Johnston , S. Kalra , J. S. Katz , H. Mitsumoto , J. Rosenfeld , C. Shoesmith , M. J. Strong , S. C. Woolley First published October 12, 2009, DOI: https://doi.org/10.1212/WNL.0b013e3181bc0141 R

2009 American Academy of Neurology

112. What is the Role of Drug Therapy in Treating Obesity?

, including Medicare and Medicaid, do not cover prescription drug costs for weight loss medications, forcing patients to pay as much as $140 per month for the FDA-approved drugs sibutramine and orlistat. Obesity represents the second leading cause of preventable death in this country 4 and an effective treatment has the potential to save millions of lives. Just a 10% reduction in weight has a major beneficial impact on cardiovascular risk factors alone. 16 The currently approved medications and those (...) What is the Role of Drug Therapy in Treating Obesity? What is the Role of Drug Therapy in Treating Obesity? – Clinical Correlations Search What is the Role of Drug Therapy in Treating Obesity? November 19, 2009 6 min read Arlene Chung Faculty Peer Reviewed Despite the high prevalence of obesity 1 and its associated morbidity 2 and mortality 3,4 , it represents one of the most difficult chronic conditions to treat. Barriers include a metabolically toxic environment, a history of ill-fated weight

2009 Clinical Correlations

113. Evaluation of Ocular Side Effects in the Patients on Topiramate Therapy for Control of Migrainous Headache Full Text available with Trip Pro

Evaluation of Ocular Side Effects in the Patients on Topiramate Therapy for Control of Migrainous Headache Topiramate, a sulfa-derivative monosaccharide, is an antiepileptic drug which is administered in the control of migraine. It is reported to cause various ocular side effects such as visual field defect and myopic shift. To investigate the alterations in refractive error, properties of the cornea and changes in the anterior chamber in patients that receive Topiramate for migraine (...) control.This is a hospital-based, non-interventional, observational study that is conducted at Imam Hossein Hospital, affiliated to Shahid Beheshti University of Medical Sciences, Department of Neurology, in collaboration with the department of Ophthalmology. Thirty three consecutive patients with the diagnosis of migraine that were candidate for Topiramate therapy were recruited. Patients with history of ocular trauma or surgery, keratoconus, glaucoma, congenital ocular malformations and any history

2016 Journal of clinical and diagnostic research : JCDR

114. Intravenous Fluid Therapy for the Treatment of Emergency Department Patients With Migraine Headache

mL) Other: Control Phase 2 Phase 3 Detailed Description: The investigators intend to perform a small-scale pilot study assessing the effectiveness of IV fluid therapy for patients presenting to the ED with migraine headache. Patients will be randomly allocated to receive a bolus of 1000 ml normal saline or no fluid bolus. Patients and outcome assessors will be blinded to the assigned study group. Research assistants will assess pain scores, nausea, and functional disability at time 0 (just prior (...) with a headache, would you wish to receive the same IV fluid treatment again?" Need for rescue medication [ Time Frame: 120 minutes ] Need for additional medications for pain control as determined by the treating physician. Length of stay [ Time Frame: 1 day ] Length of emergency department stay Pain score at 48 hours [ Time Frame: 48 hours ] Current pain as reported by participants at 48 hour follow-up (0-10 verbal scale). Nausea [ Time Frame: 60 mins, 120 mins ] Patients will be asked to describe

2016 Clinical Trials

115. Effects of physical therapy and relaxation techniques on the parameters of pain in university students with tension-type headache: A randomised controlled clinical trial. Full Text available with Trip Pro

Effects of physical therapy and relaxation techniques on the parameters of pain in university students with tension-type headache: A randomised controlled clinical trial. Non-pharmacological treatments help control tension-type headache; however, evidence about their effectiveness is still limited. This study evaluates the effectiveness of physical therapy based on cervical spine kinesiotherapy and posture correction exercises compared to a programme of relaxation techniques only (Schultz's (...) samples: AT was used in one of the groups while the other group received AT plus cervical spine kinesiotherapy and posture correction training. Patients recorded any changes in the parameters of pain (frequency, intensity, and duration) and drug consumption in a headache diary before treatment, at 4 weeks, and at 3 months.Both interventions achieved a decrease in all the parameters of pain; however, decreases in frequency and intensity were more significant in the combined treatment group (P<0.01) (d

2016 Neurologia (Barcelona, Spain) Controlled trial quality: uncertain

116. The effect of manual therapy techniques on headache disability in patients with tension-type headache. (Abstract)

The effect of manual therapy techniques on headache disability in patients with tension-type headache. Tension-type headache (TTH) is the most common type of primary headache however there is no clear evidence as to which specific treatment is most effective or whether combined treatment is more effective than individual treatments.To assess the effectiveness of manual therapy techniques, applied to the suboccipital region, on aspects of disability in a sample of patients with tension-type (...) at reducing the overall HDI score compared to the group that received suboccipital soft tissue inhibition and to the control group (both P<0.05). In addition, photophobia, phonophobia and pericranial tenderness only improved in the group receiving combined therapy (P<0.05).When given individually, suboccipital soft tissue inhibition and occiput-atlas-axis manipulation resulted in changes in different parameters related to the disability caused by TTH. However, when the two treatments were combined

2014 European journal of physical and rehabilitation medicine Controlled trial quality: uncertain

117. Drugs for the Management of Rheumatoid Arthritis

, conventional synthetic disease-modifying antirheumatic drugs (alone or in combination), biologics (including biosimilars), and targeted synthetic disease-modifying antirheumatic drugs appear to be effective for different outcomes. It is unclear how the efficacy and safety of the treatments compare with one another. The treatment outcomes of most importance to patients are disease remission or low disease activity, with improved fatigue and decreased pain also being of high importance. The decision (...) of the next treatment option should be based on a discussion between the clinician and patient that takes into consideration benefits and harms, patient treatment goals and tolerance for side effects, accessibility of treatment (e.g., whether travel is necessary), and affordability. Context Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects joints throughout the body, causing pain, swelling, stiffness, and joint damage. Approximately 300,000 Canadians have RA. Untreated, it can lead

2018 CADTH - Health Technology Assessment

118. Monarch external Trigeminal Nerve Stimulation System for drug-refractory epilepsy

? Should be taken out of use ? Nearly established AUSTRALIAN THERAPEUTIC GOODS ADMINISTRATION APPROVAL ? Yes ARTG number ? No ? Not applicable INTERNATIONAL UTILISATION LEVEL OF USE COUNTRY Trials underway or completed Limited use Widely diffused Australia ? Canada ? Europe ? Japan ? United Kingdom ? United States ? IMPACT SUMMARY Zevalin ® (Spectrum Pharmaceuticals), a combination product consisting of tiuxetan and radiolabelled ibritumomab, belongs to a group of cancer drugs known as monoclonal (...) it is not associated with the same adverse effects (AEs) seen with standard therapies, e.g. fatigue, nausea/vomiting, hair loss) (American Cancer Society 2010). MAbs are the most widely used form of cancer immunotherapy. MAbs are developed to recognise a specific antigen found on the surface of the target cancer cell. Once the antibodies are given to a patient, they can then recruit other parts of the patient’s immune system to destroy the cancer cells. Conjugated MAbs are those with a drug, toxin or radioactive

2018 COAG Health Council - Horizon Scanning Technology Briefs

119. CRACKCast E152 – Cardiovascular Drugs

CRACKCast E152 – Cardiovascular Drugs CRACKCast E152 - Cardiovascular Drugs - CanadiEM CRACKCast E152 – Cardiovascular Drugs In by Chris Lipp February 26, 2018 This episode of CRACKCast covers Rosen’s 9th Ed Chapter 147, Cardiovascular Drugs. With increasingly common use of these medications for heart disease and an ever aging population, it is imperative to understand the prompt recognition and therapy for toxic exposures. Recognition of the more lethal agents and how to disposition (...) tachycardia and ventricular fibrillation , and cardiogenic shock Special concerns: ● Amlodipine: can cause a reflex tachycardia and hypotension ● Calcium influx into the pancreas is blocked = leading to hyperglycemia ● Pediatrics: Nifedipine, verapamil, and probably other drugs in its class join the short list of medications that can kill a child with ingestion of a single tablet. Seizures may be more common in children than in adults and should be treated with diazepam, lorazepam, or phenobarbital

2018 CandiEM

120. Methamphetamine (Canadian Drug Summary)

within one hour, it takes 12 hours for 50% of methamphetamine to be removed from the body. 6 Other physical effects of methamphetamine include decreased appetite, headache, dizziness, stomach pain, dry mouth and hyperthermia (elevated body temperature), and increased breathing, heart rate and blood pressure. 2,5 Depending on the route of administration, the high from methamphetamine can last up to 12 hours. 4 Long Term: When methamphetamine is used regularly over a long period, there is an increased (...) Methamphetamine seizures in Medicine Hat increased from 369 grams in 2015 to 3,207 grams in 2017, an increase of almost 870%. ? International: The 2018 World Drug Report indicated that global quantities of methamphetamine seized in 2016 increased for a fourth consecutive year at 12%. 16 Methamphetamine also made up 12% of global drug seizures in 2015–2016 and was the third most common drug category seized after cannabis herb and cannabis resin. Methamphetamine also accounted for the largest share of global

2018 Canadian Centre on Substance Abuse

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