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Medication Causes of Headache

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41. Simplified guideline for prescribing medical cannabinoids in primary care

, CINV, and spasticity due to MS or SCI Management of pain • Acute pain: We strongly recommend against use of medical cannabinoids for acute pain management owing to evidence of no benefit and known harms (strong recommendation) • Headache: We recommend against use of medical cannabinoids for headache owing to lack of evidence and known harms (strong recommendation) • Rheumatologic pain: We recommend against use of medical cannabinoids for pain associated with rheumatologic conditions (including (...) drafted between meetings, shared ahead, and then dis- cussed at subsequent meetings. During this process, the PGC members had 7 additional questions they requested clarification on from the Evidence Review Group: • What is the evidence on medical cannabinoids for appetite stimulation? • Do cannabinoids reduce seizure frequency in patients with epilepsy? • Can cannabinoids be used to treat headaches? • Have there been any cases of pulmonary aspergillosis and, if so, was the cannabis smoked or vaporized

2018 CPG Infobase

42. Guideline for primary care management of headache in adults

acute and prophylactic medication appropriately Based on expert opinion of the Guideline Development Group. Box 6. Pharmacologic prophylaxis for migraine Prophylactic medication is indicated in the following circumstances: Recurrent migraine attacks are causing considerable disability despite optimal acute drug therapy Frequency of acute medication use is approaching levels that place the patient at risk of medication-overuse headache -acute medications are used on ≥ 10 d/mo for triptans, ergots (...) headache caused by simple analgesics (acetaminophen, NSAIDs) or triptans; however, gradual withdrawal is also an option -gradual withdrawal should be advised for patients with suspected medication-overuse headache caused by opioids and opioid-containing analgesics Provision of a prophylactic medication while medication overuse is stopped. While many prophylactic agents are used (tricyclics, β-blockers, etc), drugs with the best evidence for efficacy in chronic migraine with medication overuse

2015 Institute of Health Economics

43. American Gastroenterological Association Institute Guideline on the Medical Management of Opioid-Induced Constipation

with suspected OIC involves first taking a careful history to evaluate defecation patterns; dietary patterns; stool consistency; symptoms of dyssynergic defecation (eg, a sensation of incomplete evacuation); or alarm symptoms, such as blood in stool or accompanying weight loss. A medical history should also be taken to assess comorbid illnesses and regular medication use. Other potential causes or contributors to constipation should be explored and excluded, such as pelvic outlet dysfunction, mechanical (...) ., Dorn, S.D. et al. American Gastroenterological Association medical position statement on constipation. Gastroenterology . 2013 ; 144 : 211–217 | | | | | Once a diagnosis of OIC has been confirmed and other potential causes of constipation are excluded, the recommendations here can help guide appropriate evidence-based management. This guideline focuses on the medical management of OIC. Therefore, it does not address the role of psychological therapy, alternative medicine approaches, surgery

2019 American Gastroenterological Association Institute

44. PEER Simplified Guideline: Medical Cannabinoids

for some types of pain, chemotherapy-induced nausea and vomiting, and spasticity due to multiple sclerosis or spinal cord injury. MANAGEMENT OF PAIN ACUTE PAIN X DO NOT prescribe medical cannabinoids for acute pain management, due to evidence of no benefit and known harms. [Strong recommendation] HEADACHE X DO NOT prescribe medical cannabinoids for headache, due to the lack of evidence and known harms. a [Strong recommendation] RHEUMATOLOGIC PAIN X DO NOT prescribe medical cannabinoids for pain (...) AND VOMITING Due to the absence of evidence and known harms of medical cannabinoids, the PGC recommends against cannabinoids for general nausea/vomiting. Due to the additional unknown harms to the unborn fetus caused by medical cannabinoids in pregnancy-induced nausea/vomiting or hyperemesis gravidarum, the recommendation against cannabinoid use for these conditions was strengthened. PEER Simplified Guideline: Medical Cannabinoids | January 2018 Clinical Practice Guideline Page 12 of 26 Background

2018 Toward Optimized Practice

45. Is Subcutaneous Sumatriptan an Effective Treatment For Adults Presenting to the Emergency Department With Acute Migraine Headache?

methodological quality, many did not clearly describe methods of ra- ndomization, concealment alloca- tion, and blinding. A sensitivity anal- ysis revealed that small study size and missing data did not affect their ?ndings. No analysis was completed excluding lower-quality studies be- cause of insuf?cient data. In regard to secondary outcomes, sumatriptan compared with placebo showed greater relief of headache- associated symptoms, including na- usea, photophobia, and phonopho- bia, as well as a requirement (...) for less rescue medication. However, sumatriptan was also found to have more adverse events, such as sensa- tions of heat, tingling, chest disco- mfort, and injection-site reactions, even though they tended to be self- limiting. Comparison of subcutaneous sumatriptan versus placebo. Outcome RR (95% CI) NNT (95% CI) No. of Attacks Treated Pain free at 1 h 5.5 (4.5–6.8) 2.9 (2.7–3.2) 3,592 Headache relief at 1 h 2.7 (2.5–2.9) 2.2 (2.1–2.4) 5,177 24-h sustained pain free 2.2 (1.6–2.9) 6.1 (4.8–8.2) 752 RR

2013 Annals of Emergency Medicine Systematic Review Snapshots

46. Oral antifungal medication for toenail onychomycosis. (PubMed)

Oral antifungal medication for toenail onychomycosis. Fungal infection of the toenails, also called onychomycosis, is a common problem that causes damage to the nail's structure and physical appearance. For those severely affected, it can interfere with normal daily activities. Treatment is taken orally or applied topically; however, traditionally topical treatments have low success rates due to the nail's physical properties. Oral treatments also appear to have shorter treatment times (...) effective than placebo for achieving clinical cure (risk ratio (RR) 6.00, 95% confidence interval (CI) 3.96 to 9.08, 8 studies, 1006 participants) and mycological cure (RR 4.53, 95% CI 2.47 to 8.33, 8 studies, 1006 participants). Adverse events amongst terbinafine-treated participants included gastrointestinal symptoms, infections, and headache, but there was probably no significant difference in their risk between the groups (RR 1.13, 95% CI 0.87 to 1.47, 4 studies, 399 participants, moderate-quality

2017 Cochrane

47. Patient with a Subarachnoid Headache (PubMed)

Patient with a Subarachnoid Headache Subarachnoid hemorrhage (SAH) is a life-threatening cause of headache. The diagnostic approach to this entity continues to evolve with a recent questioning of the classic workup of computed tomography and lumbar puncture. We report a risk management case of a patient with a missed SAH resulting in a fatal outcome. When there are multiple diagnostic strategies, the patient may be involved with shared decision-making. Some of the medical and legal implications

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2018 Clinical Practice and Cases in Emergency Medicine

48. Global, regional, and national burden of migraine and tension-type headache, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. (PubMed)

multiplied by disability weights (a measure of the relative severity of the disabling consequence of a disease). The burden stemming from medication overuse headache, which was included in earlier iterations of GBD as a separate cause, was subsumed as a sequela of either migraine or tension-type headache. Because no deaths were assigned to headaches as the underlying cause, YLDs equate to disability-adjusted life-years (DALYs). We also analysed results on the basis of the Socio-demographic Index (SDI (...) ), a compound measure of income per capita, education, and fertility.Almost three billion individuals were estimated to have a migraine or tension-type headache in 2016: 1·89 billion (95% uncertainty interval [UI] 1·71-2·10) with tension-type headache and 1·04 billion (95% UI 1·00-1·09) with migraine. However, because migraine had a much higher disability weight than tension-type headache, migraine caused 45·1 million (95% UI 29·0-62·8) and tension-type headache only 7·2 million (95% UI 4·6-10·5) YLDs

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2018 Lancet Neurology

49. The Prevalence and Impact of Migraine and Severe Headache in the United States: Figures and Trends From Government Health Studies. (PubMed)

conditions.We searched for the most current publicly available summary statistics from the National Health Interview Survey (NHIS), the National Hospital Ambulatory Medical Care Survey (NHAMCS), and the National Ambulatory Medical Care Survey (NAMCS). We extracted and summarized data from each study over time and as a function of demographic variables.The prevalence and burden of self-reported migraine and severe headache in the US adult population is high, affecting roughly 1 out of every 6 American and 1 (...) are unemployed (21.4%), those with family income less than $35,000 per year (19.9%), and the elderly and disabled (16.4%). Headache is consistently the fourth or fifth most common reason for visits to the emergency department, accounting for roughly 3% of all emergency department visits annually. In reproductive aged women, headache is the third leading cause of emergency department visits.Severe headache and migraine remain important public health problems that are more common and burdensome for women

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2018 Headache

50. Benign Headache Management in the Emergency Department. (PubMed)

of emergency evaluation of these patients include evaluation for a life-threatening, secondary cause of headache, with treatment of primary headaches. Close evaluation for a secondary cause of headache include consideration of red flags and focused neurologic examination. The diagnosis of primary headaches is clinical. Literature has evaluated medication efficacy in headache treatment, with antidopaminergic medications demonstrating high rates of efficacy when used in combination with nonsteroidal (...) Benign Headache Management in the Emergency Department. Headache is a common complaint managed in the emergency department (ED), with emergency physicians focusing on evaluation for life-threatening conditions while treating pain and nausea.This review evaluates the treatment of benign, primary headaches in the ED, with recommendations provided based on the literature.Headaches are a major cause of disability in the United States and a common condition managed in the ED. The primary objectives

2018 Journal of Emergency Medicine

51. Diagnosis and Management of Headache in Older Adults. (PubMed)

Diagnosis and Management of Headache in Older Adults. Headache is a common, disabling neurologic problem in all age groups, including older adults. In older adults, headache is most likely a primary disorder, such as tension-type headache or migraine; however, there is a higher risk of secondary causes, such as giant cell arteritis or intracranial lesions, than in younger adults. Thus, based on the headache history, clinical examination, and presence of headache red flags, a focused diagnostic (...) evaluation is recommended, ranging from blood tests to neuroimaging, depending on the headache characteristics. Regardless of the primary or secondary headache disorder diagnosis, treatment options may be limited in older patients and may need to be tailored to the presence of comorbid medical conditions. The purpose of this review is to provide an update on the management of headache in older adults, from diagnosis to treatment.Copyright © 2017 Mayo Foundation for Medical Education and Research

2018 Mayo Clinic Proceedings

52. Mindfulness for female outpatients with chronic primary headaches: an internet-based bibliotherapy (PubMed)

treatment and some limitations that such interventions may cause, patients may be encountered with problems when using health care services. The present study is a quasi-experimental randomized design with pre-test, post-test, and control group. The study population consisted of 1396 women with migraine headache referring to headache clinic of Baqiyatallah Hospital in Tehran. Of these, 30 patients (including tboh experimental and control group) were selected by objective sampling method and were (...) Mindfulness for female outpatients with chronic primary headaches: an internet-based bibliotherapy Our aim was to investigate effectiveness of mindfulness by bibliotherapy on disability, distress, perceived pain and mindfulness in women with tension headaches and migraines. Primary headaches have been of great interest to mental health researchers because of the high prevalence, as well as significant disability and distress in the affected people. Despite the promising results of in-person

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2018 European journal of translational myology

53. Prediction of vascular abnormalities on CT angiography in patients with acute headache (PubMed)

Prediction of vascular abnormalities on CT angiography in patients with acute headache Patients with acute headache increasingly undergo CT-angiography (CTA) to evaluate underlying vascular causes. The aim of this study is to determine clinical and non-contrast CT (NCCT) criteria to select patients who might benefit from CTA.We retrospectively included patients with acute headache who presented to the emergency department of an academic medical center and large regional teaching hospital (...) and underwent NCCT and CTA. We identified factors that increased the probability of finding a vascular abnormality on CTA, performed multivariable regression analyses and determined discrimination with the c-statistic.A total of 384 patients underwent NCCT and CTA due to acute headache. NCCT was abnormal in 194 patients. Among these, we found abnormalities in 116 cases of which 99 aneurysms. In the remaining 190 with normal NCCT we found abnormalities in 12 cases; four unruptured aneurysms, three cerebral

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2018 Brain and behavior

54. Primary Headache and Psychological Factors, Mental Functioning and Attachment Modalities.

Posted : April 17, 2018 Last Update Posted : April 17, 2018 See Sponsor: Centre Hospitalier Universitaire de Besancon Information provided by (Responsible Party): Centre Hospitalier Universitaire de Besancon Study Details Study Description Go to Brief Summary: The World Health Organization (WHO) ranks headache among the top 20 causes of disability in the world. Primary headaches (with no known organic cause) account for 90% of these conditions. INSERM estimates that 15% of the general population (...) Studies updated these recommendations in 2013. They are focused on the medical management offered by doctors and pharmacists. However, the professionals in daily contact with the subjects know that the dimension psychic plays an important role in the etiology of headaches. Condition or disease Intervention/treatment Phase Primary Headache Disorder Other: psychological tests Not Applicable Detailed Description: The review of the literature shows the keen interest and the need for this type of research

2018 Clinical Trials

55. Introvision for Migraine and Headaches

by the patients themselves with a scale in the headache diary: weak (=1) , moderate (=2), severe (=3) headache. Scores may range from 1 to 3. Average headache intensity of the attacks per months will be compared three months after the last session of Introvision compared to the waiting list group before Introvison. acute medication per month [ Time Frame: approximately 4 months, experimental group compared to the waiting list group ] The number of days with acute medication against migraine attacks/headache (...) per month 3 months after completion of the last session of Introvision will be compared with the number of days with acute medication per month of the waiting list group in the month before the course to learn Introvision. number of headache days per month in pooled groups analysis before and 3 months after Introvision as parameter for the efficacy of Introvision [ Time Frame: approximately 5-6 months ] number of headache days per months in pooled groups analysis before and 3 months after

2018 Clinical Trials

56. Long Term Outcomes Following a Post Dural Puncture Headache

Dural Puncture Headache The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03550586 Recruitment Status : Recruiting First Posted : June 8, 2018 Last Update Posted : June 8, 2018 See Sponsor: Rabin Medical Center Collaborator (...) : Assaf-Harofeh Medical Center Information provided by (Responsible Party): Rabin Medical Center Study Details Study Description Go to Brief Summary: Epidural analgesia is considered a gold standard method for treatment of labor pain. One of the major risks with epidural analgesia is an accidental dural puncture, which leads to a post dural puncture headache. This headache is associated with significant maternal morbidity and can result in severe maternal consequences. Post traumatic stress disorder

2018 Clinical Trials

57. Effectiveness of Manual Therapy vs Exercises With Foam Rolling for Tension Headache

Effectiveness of Manual Therapy vs Exercises With Foam Rolling for Tension Headache Effectiveness of Manual Therapy vs Exercises With Foam Rolling for Tension Headache - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Effectiveness of Manual Therapy vs Exercises With Foam Rolling for Tension Headache (MTvsFR-TTH) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03591601 Recruitment Status : Completed First Posted : July 19, 2018 Last Update Posted : February 5, 2019 Sponsor: University of Valencia

2018 Clinical Trials

58. Efficacy of Kinesio Taping in Tension Type Headache

targeting this area moderate or excessive nausea and vomiting with headache headache due to other causes (e.g., subarachnoid hemorrhage, cerebral hemorrhage, cerebral embolism, cerebral thrombosis, vascular malformation, arthritis, hypertension, or arteriosclerosis) have used prophylactic headache medications in the last 3 months neurological, mental, hemorrhagic disease, allergy, serious heart, liver, kidney and other organ deficiencies Contacts and Locations Go to Information from the National Library (...) Efficacy of Kinesio Taping in Tension Type Headache Efficacy of Kinesio Taping in Tension Type Headache - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Efficacy of Kinesio Taping in Tension Type Headache

2018 Clinical Trials

59. SubArachnoid Hemorrhage HEadache Treated by Lumbar Puncture

: University Hospital, Toulouse Information provided by (Responsible Party): University Hospital, Toulouse Study Details Study Description Go to Brief Summary: Headache control is one of the major challenges in patients who suffered an acute aneurysmal subarachnoid hemorrhage (aSAH). Headache affects 90% of the patient and is resistant to the major pain medication. It results from the increased intracranial pressure and the inflammation caused by the accumulation of arterial blood in the subarachnoid space (...) will be assessed using the verbal rating scales (VRS). It is a scale administered by the medical team, which brings together the score given by the patient between 0 and 10 (0 = absence of pain; 10 = maximum of conceivable pain)Headache mean intensity variation will be calculated by the difference between these scores evaluated 24 hours before and the 24 hours after the procedure. Secondary Outcome Measures : Difference of variation in the mean intensity of headache [ Time Frame: 48 hours ] Difference

2018 Clinical Trials

60. Pediatric headache: overview. (PubMed)

Pediatric headache: overview. Headache is a common medical complaint in children and adolescents with the majority having experienced some type of headache by their teenage years. Pediatric headache presentations often differ compared to adults, and children may have difficulty describing their symptoms. Thus, a thorough understanding of the approach to the pediatric headache patient is essential to ensure appropriate diagnosis, evaluation, and management.In the following article we will review (...) the components of a comprehensive pediatric headache assessment, as well as discuss primary and secondary headache types seen in children with focus on clinical pearls and 'red flags' necessitating diagnostic testing.Headaches in children may be due to primary or secondary etiologies. Common primary headache types include migraine or tension-type headache. Secondary headache causes are broad and include infections, trauma, vascular disorders, substance use/withdrawal, and psychiatric conditions. Current

2018 Current Opinion in Pediatrics

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