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Medication Causes of Dyspepsia

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921. What is the evidence for the use of warfarin or antiplatelet medication in patients with atrial fibrillation?

What is the evidence for the use of warfarin or antiplatelet medication in patients with atrial fibrillation? What is the evidence for the use of warfarin or antiplatelet medication in patients with atrial fibrillation? - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere (...) clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com What is the evidence for the use of warfarin or antiplatelet medication in patients with atrial fibrillation? Clinical Evidence has a number of pages detailing the evidence

2004 TRIP Answers

922. An evidence-based approach to the management of uninvestigated dyspepsia in the era of Helicobacter pylori

, hepatobiliary and other nongastrointestinal origins of the presenting dyspeptic symptoms, including possible medication-induced dyspepsia, lifestyle or dietary indiscretions. Although it may be difficult to exclude all of these causes on history-taking, it is important to know when to investigate further. Box B: Older patients and patients with alarm features Although cancer is a rare cause of dyspeptic symptoms (accounting for less than 2% of cases), it is an important consideration. Alarm features (...) the medical literature and clinical expertise to aid decision-making in patient care. The Canadian Dyspepsia (CanDys) Working Group was convened with the mandate to develop an evidence-based management tool for uninvestigated dyspepsia that would be practical and would reflect the realities of the primary care setting. The aim was to provide primary care physicians with recommendations and guidance concerning appropriate investigations, treatments and indications for referral for patients

2000 CPG Infobase

923. Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease

Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) more. Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00260572 Recruitment Status : Active, not recruiting First Posted : December 1, 2005 Last Update Posted : August 21, 2018 Sponsor: University of Pittsburgh

2005 Clinical Trials

924. Therapy for Helicobacter pylori in patients with nonulcer dyspepsia: a meta-analysis of randomised controlled trials

of nonulcer dyspepsia. Searching MEDLINE and HealthSTAR were searched from 1984 to 1999 with no language restrictions; the search terms were reported. Proceedings from the annual meetings of the American College of Gastroenterology, American Gastroenterological Association, and European H. pylori Study Groups (1995 to 1999), and reference lists of retrieved articles and reviews that met the inclusion criteria, were also searched. Manufacturers of H. pylori medications and experts in the field were (...) suggested continued evaluation of the causes of nonulcer dyspepsia is needed. Bibliographic details Laine L, Schoenfeld P, Fennerty M B. Therapy for Helicobacter pylori in patients with nonulcer dyspepsia: a meta-analysis of randomised controlled trials. Annals of Internal Medicine 2001; 134(5): 361-369 PubMedID Original Paper URL Other publications of related interest Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical

2001 DARE.

925. Dyspepsia management in primary care: a decision analysis of competing strategies

of effectiveness data The evidence was derived from a systematic review of published studies, and from authors' assumptions. Modelling A decision tree was designed to compute the cost-effectiveness of the four strategies for the treatment of uninvestigated dyspepsia. The time horizon considered was 1 year. Outcomes assessed in the review The following clinical and effectiveness data were obtained from the literature review and included as inputs in the model: the probability that the cause of dyspepsia (...) is nonulcer dyspepsia (NUD); the probability that NUD is H. pylori positive; the probability that the cause of dyspepsia is peptic ulcer disease (PUD); the probability that PUD is H. pylori positive; the probability that the cause of dyspepsia is oesophagitis; the probability that oesophagitis is H. pylori positive; the probability that the cause of dyspepsia is gastric cancer; the probability that gastric cancer is H. pylori positive; the probability that H. pylori is successfully eradicated by the first

2002 NHS Economic Evaluation Database.

926. The Omega-Project: a comparison of two diagnostic strategies for risk- and cost-oriented management of dyspepsia

The Omega-Project: a comparison of two diagnostic strategies for risk- and cost-oriented management of dyspepsia The Omega-Project: a comparison of two diagnostic strategies for risk- and cost-oriented management of dyspepsia The Omega-Project: a comparison of two diagnostic strategies for risk- and cost-oriented management of dyspepsia Brignoli R, Watkins P, Halter F Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each (...) abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Diagnostic strategies (mandatory versus selective endoscopy) for risk- and cost-oriented management of dyspepsia. Type of intervention Diagnosis. Economic study type Cost-effectiveness analysis. Study population Adult (male and female) patients with dyspeptic disorders (for at least one month) who were

1997 NHS Economic Evaluation Database.

927. In a person presenting with symptoms of dyspepsia, what is the appropriate management plan?

if the person has any ALARM symptoms (see Refer?). Address anxieties about the significance of symptoms. Stop nonsteroidal anti-inflammatory drugs (NSAIDs) where possible. If this is not possible, see Scenario: Dyspepsia while taking NSAID. Review other medication that may be causing dyspepsia: corticosteroids; bisphosphonates; medication that may lower oesophageal sphincter pressure (e.g. theophylline, nitrates, and calcium-channel blockers). Choose a first-line treatment strategy. Either: - Test (...) In a person presenting with symptoms of dyspepsia, what is the appropriate management plan? In a person presenting with symptoms of dyspepsia, what is the appropriate management plan? - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches

2007 TRIP Answers

928. Evaluation of Food Hypersensitivity in Children/Adolescents With Functional Dyspepsia

Information provided by: Children's Mercy Hospital Kansas City Study Details Study Description Go to Brief Summary: The main purpose of this study is to determine if standard and investigational tests used to help diagnose and treat food allergies can provide information that will be useful in determining the cause of dyspepsia and helpful in designing a treatment plan. The study will also determine if there is a connection between positive allergy tests and inflammation in the upper abdomen. Condition (...) Evaluation of Food Hypersensitivity in Children/Adolescents With Functional Dyspepsia Evaluation of Food Hypersensitivity in Children/Adolescents With Functional Dyspepsia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2006 Clinical Trials

929. The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia.

. At the time of Screening, have at least one other symptom of FD for at least one day each week in the last month. Exclusion Criteria: Have a known hypersensitivity to dexloxiglumide, any PPI, or aluminum/magnesium-containing antacids Have a history of organic diseases, structural or biochemical, of the gastrointestinal system that can cause dyspepsia. Have active irritable bowel syndrome (C-IBS, alt-IBS, D-IBS). Have findings leading to a clinical suspicion of other secondary causes of dyspepsia (...) The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia. The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2006 Clinical Trials

930. Functional Dyspepsia

the condition is usually classified as functional dyspepsia. Several disturbances of function are now known as potential causes of such symptoms, and the optimal choice of treatment may vary. In the study the investigators plan to examine whether different types of functional disturbances respond differently to medical therapy. In particular, the investigators want to assess whether comprehensive and individualized information will influence the results of therapy. This has not been previously studied (...) provided by (Responsible Party): Valery Glazkov, Helse Fonna Study Details Study Description Go to Brief Summary: Study title: Functional dyspepsia -- effect of acid reducing treatment and individualized information. Summary: 15-20% of all people experience dyspepsia each year. Dyspepsia means pain or discomfort in the upper part of the abdomen. Accompanying symptoms from the esophagus may be present. The most important relevant medical examination is gastroscopy, and if the findings are normal

2007 Clinical Trials

931. The Efficacy of Imipramine in Treatment of Functional Dyspepsia

): Justin Che-Yuen Wu, Chinese University of Hong Kong Study Details Study Description Go to Brief Summary: The aim of this study is evaluate the efficacy of Imipramine, a tricyclic antidepressant, in treatment of functional dyspepsia. This is a double blind randomised placebo controlled trial in which consecutive patients with diagnosis of functional dyspepsia will be studied. After exclusion of organic cause of dyspepsia by endoscopy, these patients will be randomly assigned to either imipramine (...) of upper gastrointestinal symptoms such as postprandial fullness, early satiety, pain, bloating, belching, or nausea. The pathophysiology of functional dyspepsia is not fully understood and the correlation of those proposed mechanisms with the clinical characteristics and treatment response is poor. Owing to the poor understanding on the mechanism, treatment of functional dyspepsia has been far from satisfactory. There are numerous modalities of medical treatment that has been reported to be effective

2005 Clinical Trials

932. Serotonin Effect in Functional Dyspepsia

Investigators Layout table for investigator information Study Director: Jan Jansen, Professor MD Radboud University Nijmegen Medical Center More Information Go to Layout table for additonal information ClinicalTrials.gov Identifier: Other Study ID Numbers: SEREIN First Posted: June 22, 2005 Last Update Posted: September 24, 2007 Last Verified: September 2007 Keywords provided by Radboud University: functional dyspepsia; Serotonin Uptake Inhibitors; Antidepressive Agents. Additional relevant MeSH terms (...) Serotonin Effect in Functional Dyspepsia Serotonin Effect in Functional Dyspepsia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Serotonin Effect in Functional Dyspepsia The safety and scientific validity

2005 Clinical Trials

933. Impaired gastric accommodation and its role in dyspepsia. (PubMed)

as a cause of morbidity and the methods used to assess gastric accommodation in humans. The available medical and therapeutic strategies based on the actual knowledge of the physiology and pharmacology of the accommodation reflex are outlined, with a focus on the role of nitrergic neurones and serotonergic receptors. (...) Impaired gastric accommodation and its role in dyspepsia. The accommodation reflex is an important mechanism of normal gastric physiology. In functional dyspepsia, impairment of accommodation has been found in 40% of cases, but it has been described in several other upper gastrointestinal disorders, such as diabetic gastropathy and postfundoplication syndrome. This review focuses on the pathways involved in the normal accommodation reflex, the relevance of impaired gastric accommodation

Full Text available with Trip Pro

2006 Gut

934. Why do dyspeptic patients over the age of 50 consult their general practitioner? A qualitative investigation of health beliefs relating to dyspepsia. (PubMed)

Why do dyspeptic patients over the age of 50 consult their general practitioner? A qualitative investigation of health beliefs relating to dyspepsia. The prognosis of late-diagnosed gastric cancer is poor, yet less than half of dyspeptic patients consult their general practitioner (GP).To construct an explanatory model of the decision to consult with dyspepsia in older patients.A total of 75 patients over the age of 50 years who had consulted with dyspepsia at one of two inner city general (...) practices were invited to an in-depth interview. The interviews were taped, transcribed, and analysed using the computer software NUD.IST, according to the principles of grounded theory.Altogether, 31 interviews were conducted. The perceived threat of cancer and the need for reassurance were key influences on the decision to consult. Cues such as a change in symptoms were important in prompting a re-evaluation of the likely cause. Personal vulnerability to serious illness was often mentioned

Full Text available with Trip Pro

1998 The British Journal of General Practice

935. Randomized, double-blind, placebo-controlled crossover trial of cimetidine and pirenzepine in nonulcer dyspepsia. (PubMed)

Randomized, double-blind, placebo-controlled crossover trial of cimetidine and pirenzepine in nonulcer dyspepsia. Nonulcer dyspepsia remains a difficult disorder to treat because it is a heterogeneous syndrome. Once patients with the irritable bowel syndrome, esophagitis, and other organic diseases are excluded, there remain patients with dyspepsia of unknown cause (termed "essential dyspepsia") and patients with dyspepsia plus symptoms of gastroesophageal reflux without esophagitis. The aim (...) of this study was to determine whether cimetidine or pirenzepine is efficacious in relieving the symptoms of these latter subgroups. Sixty-two consecutive patients were studied who had chronic upper abdominal pain or nausea where endoscopy had shown no evidence of peptic ulceration, esophagitis, or malignancy; 47 had essential dyspepsia, and 15 had dyspepsia plus gastroesophageal reflux. They were initially randomized to either cimetidine or placebo, or pirenzepine or placebo. Patients continued each

1986 Gastroenterology Controlled trial quality: uncertain

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