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Medication Causes of Dyspepsia

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41. Tailored Therapy for Helicobacter Pylori Treatment in Patients With Penicillin Allergy

with daily activities), or "severe" (causing considerable interference with daily activities) Compliance rate [ Time Frame: Within 7 days after completion of therapy ] Compliance was defined as poor when they had taken less than 80% of the total medication. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about (...) , 2018 Last Update Posted : December 4, 2018 See Sponsor: Shanghai Jiao Tong University School of Medicine Information provided by (Responsible Party): Hong Lu, MD, Shanghai Jiao Tong University School of Medicine Study Details Study Description Go to Brief Summary: Increasing drug resistance presents a significant challenge to the efficacies of common empiric eradication regimens for Helicobacter pylori treatment in the mainland of China. Tailored therapy may be the best choice to achieve good

2018 Clinical Trials

42. Behavioural Therapy With Checklist for Overactive Bladder

with written checklist form to complete Drug: Antimuscarinic drugs used in overactive bladder Behavioral: behavioural therapy with written guideline Not Applicable Detailed Description: Overactive bladder (OAB) can worsen quality of life but it is not life-threatening condition. Although OAB medications effectively decrease disturbing symptoms of OAB, there are a lot of adverse side effects such as dry mouth, cognitive changes, constipation, urinary retention, blurred vision and dyspepsia. Therefore (...) , weight loss and other life style changes Active Comparator: antimuscarinic drug plus verbal behavioural therapy Patients received medical treatment (once or twice per day) plus behavioural therapy without checklist over six-month period. Drug: Antimuscarinic drugs used in overactive bladder Antimuscarinic drugs (Tolterodine, solifenacin, propiverine, darifenacin,fesoterodine) Behavioral: behavioural therapy with written guideline behavioural therapy with written guideline,which are the same as those

2018 Clinical Trials

43. Tailored Therapy for Helicobacter Pylori Rescue Treatment

completion of therapy ] The subjects were asked to grade the severity of adverse events according to their influence on daily activities, experienced as "mild" (transient and well tolerated), "moderate" (causing discomfort and partially interfering with daily activities), or "severe" (causing considerable interference with daily activities). Compliance rate [ Time Frame: Within 7 days after completion of therapy ] Compliance was defined as poor when they had taken less than 80% of the total medication (...) . Other Outcome Measures: Medical cost per patient of tailored therapy [ Time Frame: Two months after completion of therapy ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information

2018 Clinical Trials

44. High Dose of Dual Therapy Plus Bismuth for Helicobacter Pylori Treatment

discomfort and partially interfering with daily activities), or "severe" (causing considerable interference with daily activities). Compliance rate [ Time Frame: Within 7 days after completion of therapy. ] Compliance was defined as poor when they had taken less than 80% of the total medication. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about (...) for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Hong Lu, MD, Shanghai Jiao Tong University School of Medicine: Helicobacter pylori Therapy Additional relevant MeSH terms: Layout table for MeSH terms Helicobacter Infections Gram-Negative Bacterial Infections Bacterial Infections Citric Acid Amoxicillin Esomeprazole Bismuth Potassium Citrate Anticoagulants Calcium Chelating Agents Chelating Agents Sequestering Agents

2018 Clinical Trials

45. Efficacy of Banha-sasim-tang on functional dyspepsia classified as excess pattern: study protocol for a randomized controlled trial Full Text available with Trip Pro

Efficacy of Banha-sasim-tang on functional dyspepsia classified as excess pattern: study protocol for a randomized controlled trial Functional dyspepsia (FD) refers to the presence of one or more gastrointestinal symptoms including postprandial fullness, epigastric pain, burning, and early satiety without an organic explanation for chronic symptoms. FD causes considerable discomfort in patients and affects their everyday activity and productivity. Because most conventional treatments have (...) limited efficacy, numerous patients seek alternatives such as herbal medicines. In this proposed study, we will conduct a clinical trial of an herbal drug, Banha-sasim-tang (BST). Furthermore, participants will be limited to those classified as having an excess pattern by using an instrument of pattern identification for FD to determine the efficacy of BST in a specific subset of patients.This randomized, blinded, parallel-group clinical trial of BST versus placebo will consist of 4 weeks of oral

2017 Trials Controlled trial quality: predicted high

46. Impaired vagal activity to meal in patients with functional dyspepsia and delayed gastric emptying Full Text available with Trip Pro

Impaired vagal activity to meal in patients with functional dyspepsia and delayed gastric emptying Objective This study was performed to investigate impaired vagal activity to meal in patients with functional dyspepsia (FD) with delayed gastric emptying (GE). Methods Eighty-five patients were studied. GE parameters, including those in the overall and proximal stomach, were measured by GE functional tests at the Department of Nuclear Medicine. Autonomic nervous function was tested by spectral (...) after a meal. Conclusion Delayed proximal GE might be caused by disrupted sympathovagal balance as a result of decreased vagal activity after a meal. Improvement in vagal activity may constitute an effective treatment method for patients with FD.

2017 The Journal of international medical research

47. Visceral Manipulation Treatment to Patients With Non-specific Neck Pain With Functional Dyspepsia

of the first thoracic vertebra, without association with any specific systemic disease provided by multifactorial and/or little known causes. Objective: The objective of the present study will be to verify the clinical effects of MV through visceral nociceptive inhibition in NS-NP patients with functional dyspepsia. Methods: In this study sixty NS-NP patients with functional dyspepsia (age: 18 and 50 years) will be randomized in into two groups: visceral manipulation group (VMG) (n =30) and control group (...) disorders (i.e., irradiated pain) or neck surgery; systemic disease; connective tissue disorder and herniated disc; current pregnancy; medical diagnosis of fibromyalgia; physical therapy treatment with, massage, or acupuncture in the previous two weeks; use of analgesic, muscle relaxant, psychotropic agent, or anti-inflammatory agent in the previous three days; chronic neck pain resulting from a traumatic incident; chronic musculoskeletal condition (e.g., muscular disorder, polyarthritis). Contacts

2017 Clinical Trials

48. The Effect of Gluten-free Diet in Type 1 Diabetics With Dyspepsia Symptoms

. Exclusion Criteria: Patients with very severe symptoms of gastroparesis that require specialized nutritional therapy or surgical treatment; Pregnant women; Patients with concomitant diseases/treatments that can alter gastrointestinal motility and concomitant severe systemic diseases. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor (...) Posted: March 24, 2017 Last Update Posted: December 20, 2017 Last Verified: December 2017 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by McMaster University: gluten-free diet gluten sensitivity dyspepsia diabetes mellitus, type 1 gastroparesis motility Additional relevant MeSH terms: Layout table for MeSH terms Diabetes

2017 Clinical Trials

49. Trial to Reduce Inappropriate Oesophagogastroduodenoscopies for Dyspepsia

: The Netherlands Organisation for Health Research and Development Maastricht University Medical Center Canisius-Wilhelmina Hospital VieCuri Medical Centre Information provided by (Responsible Party): Radboud University Study Details Study Description Go to Brief Summary: Indigestion or dyspepsia is highly prevalent worldwide. Often these symptoms are of benign nature and subside without treatment, or with lifestyle interventions like dietary modifications. Too often, gastroscopy is performed because (...) Dyspepsia Indigestion Device: e-learning Not Applicable Detailed Description: Rationale: Upper gastrointestinal (GI) symptoms, such as dyspepsia without alarm symptoms, are highly prevalent in the general population. Lifestyle modifications and medication can reduce symptoms in most patients. Guidelines state that oesophagogastroduodenoscopy (OGD) is only indicated in a selected high risk group. In spite of these guidelines, OGD referrals for dyspepsia without alarm symptoms are still substantial

2017 Clinical Trials

50. Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study. Full Text available with Trip Pro

Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study. Functional dyspepsia (FD) is a constellation of epigastric symptoms originating in the gastroduodenal region without organic and metabolic cause. However, similar confounding symptoms can also appear in patients with gallbladder (GB) dyskinesia. Therefore, symptoms of GB dyskinesia may be mistaken for FD. We aimed to identify GB dyskinesia as a cause of FD symptoms compatible (...) with the Rome IV criteria and the need for an evaluation of GB function in patients with FD symptoms.We investigated information of patients with FD symptoms who underwent a quantitative Tc-diisoproyl iminodiacetic acid cholescintigraphy (DISIDA scan) through electronic medical records, and GB dyskinesia was judged to be the cause of the FD symptoms if the symptoms disappeared as GB function normalized on the follow-up DISIA scan in patient with decreased GB function on the initial DISIDA scan.A total

2017 Medicine

51. Pharmacologic Therapy for Pulmonary Arterial Hypertension in Adults

are approved for therapy for patients with PH due to left -sided heart disease or chronic hypoxemic lung disease. Th e limited evidence available regarding the use of these drugs in patients with PH due to left -sided heart disease or hypoxemic lung disease has not demonstrated benefi t overall and in some cases suggests the potential for signifi cant harm. Further, failure to correctly identify or address the cause of PH may deny the patient benefi cial treatment (eg, for left -sided heart disease (...) of our patients, who risk their well-being as volunteer participants in clinical studies. Met h o d s Th e goal of this CHEST guideline project was to produce clinically relevant and useful recommendations on medical therapies for PAH for clinicians who treat adult patients with PAH. Health-care providers should use these guidelines to assist patients with treatment choices that optimize benefi ts and minimize harms and burdens. In 2011, the Institute of Medicine (IOM) released new guideline

2014 American College of Chest Physicians

52. Dyspepsia

to higher doses Adjunctive medication options Metoclopramide (prokinetic agent) May offer benefit in Nonulcer Dyspepsia Risk of tardive diskinesia Ineffective Medications (avoid) Sucralfate offers no benefit in Nonulcer Dyspepsia Misoprostel offers no benefit in Nonulcer Dyspepsia XII. Approach: Step 4 - Consider Helicobacter Pylori testing Indications Lack of relief with empiric antisecretory therapy Undifferentiated Dyspepsia treatment does not benefit without ulcer However ulcer status unknown (...) (MEDLINEPLUS) Nearly everyone has had indigestion at one time. It's a feeling of discomfort or a burning feeling in your upper abdomen. You may have or belch and feel bloated. You may also feel nauseated, or even throw up. You might get indigestion from eating too much or too fast, eating high-fat foods, or eating when you're stressed. Smoking, drinking too much alcohol, using some medicines, being tired, and having ongoing stress can also cause indigestion or make it worse. Sometimes the cause

2018 FP Notebook

53. Schizophrenia: omega-3 fatty acid medicines

, therefore the use of approved medicinal products for this indication is off-label. The place in therapy of omega-3 fatty acid medicines for their licensed indications is covered in several NICE clinical guidelines. These are summarised in the key therapeutic topic publication on omega-3 fatty acids, which supports the Quality, Innovation, Productivity and Prevention (QIPP) medicines use and procurement work stream. In line with the guidance from the General Medical Council (GMC (...) interv Pharmacological interventions entions For people with newly diagnosed schizophrenia, offer oral antipsychotic medication. Provide information and discuss the benefits and side-effect profile of each drug with the service user. The choice of drug should be made by the service user and healthcare professional together, considering: the relative potential of individual antipsychotic drugs to cause extrapyramidal side effects (including akathisia), metabolic side effects (including weight gain

2013 National Institute for Health and Clinical Excellence - Advice

54. A Randomized Trial Comparing Empirical and Guided Therapy for Unexplained Non-Cardiac Chest Pain

effectiveness in relieving chest pain (frequency and severity) will assessed after 2 weeks and 8 weeks of therapy with Gastroesophageal Reflux Disease Questionnaire (GERDQ) and Quality of Life Reflux and Dyspepsia (QOLRAD) questionnaire, and visual analogue scale (VAS) (score 1-10). Condition or disease Intervention/treatment Phase Non Cardiac Chest Pain Drug: Empirical therapy group Drug: Guided therapy group Phase 2 Phase 3 Detailed Description: Non-cardiac chest pain (NCCP) is very common in the general (...) extended release lansoprazole (Dexlansoprazole, Takeda Pharmaceuticals, Japan) 60 mg daily for 2 weeks Drug: Empirical therapy group Receive extended release lansoprazole (Dexlansoprazole, Takeda Pharmaceuticals, Japan) 60 mg daily for 2 weeks. Other Name: Dexlansoprazole Experimental: Guided therapy group Participants will be give Dexlansoprazole 30 mg daily for GERD, 60 mg daily for GERD with erosive esophagitis for 8 weeks and Theophylline SR 250 mg daily for functional chest pain for 4 weeks. Drug

2017 Clinical Trials

55. The increasing prevalence of HIV/Helicobacter pylori co-infection over time, along with the evolution of antiretroviral therapy (ART) Full Text available with Trip Pro

The increasing prevalence of HIV/Helicobacter pylori co-infection over time, along with the evolution of antiretroviral therapy (ART) Helicobacter pylori (H. pylori) is one of the most common human bacterial infections with prevalence rates between 10-80% depending upon geographical location, age and socioeconomic status. H. pylori is commonly found in patients complaining of dyspepsia and is a common cause of gastritis. During the course of their infection, people living with HIV (PLHIV) often (...) antiretroviral therapy (ART) has evolved, from pre- highly active antiretroviral therapy (HAART) to early and modern HAART eras. These data were compared to well-matched HIV negative controls. Two hundred and twelve PLHIV were compared with 1,617 controls who underwent their first esophagogastroduodenoscopy (EGD) to investigate dyspepsia. The prevalence of H. pylori co-infection among PLHIV was significantly higher in the early (30.2%) and modern HAART period (34.4%) compared with those with coinfection from

2017 PeerJ

56. Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study Full Text available with Trip Pro

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study Autism spectrum disorders (ASD) are complex neurobiological disorders that impair social interactions and communication and lead to restricted, repetitive, and stereotyped patterns of behavior, interests, and activities. The causes of these disorders remain poorly understood, but gut microbiota, the 1013 bacteria in the human intestines, have been implicated because children (...) trial evaluated the impact of Microbiota Transfer Therapy (MTT) on gut microbiota composition and GI and ASD symptoms of 18 ASD-diagnosed children.MTT involved a 2-week antibiotic treatment, a bowel cleanse, and then an extended fecal microbiota transplant (FMT) using a high initial dose followed by daily and lower maintenance doses for 7-8 weeks. The Gastrointestinal Symptom Rating Scale revealed an approximately 80% reduction of GI symptoms at the end of treatment, including significant

2017 Microbiome

57. Randomised clinical trial: addition of alginate-antacid (Gaviscon Double Action) to proton pump inhibitor therapy in patients with breakthrough symptoms. Full Text available with Trip Pro

Randomised clinical trial: addition of alginate-antacid (Gaviscon Double Action) to proton pump inhibitor therapy in patients with breakthrough symptoms. Symptomatic breakthrough in proton pump inhibitor (PPI)-treated gastro-oesophageal reflux disease (GERD) patients is a common problem with a range of underlying causes. The nonsystemic, raft-forming action of alginates may help resolve symptoms.To assess alginate-antacid (Gaviscon Double Action, RB, Slough, UK) as add-on therapy to once-daily (...) PPI for suppression of breakthrough reflux symptoms.In two randomised, double-blind studies (exploratory, n=52; confirmatory, n=262), patients taking standard-dose PPI who had breakthrough symptoms, assessed by Heartburn Reflux Dyspepsia Questionnaire (HRDQ), were randomised to add-on Gaviscon or placebo (20 mL after meals and bedtime). The exploratory study endpoint was change in HRDQ score during treatment vs run-in. The confirmatory study endpoint was "response" defined as ≥3 days reduction

2017 Alimentary Pharmacology & Therapeutics Controlled trial quality: predicted high

58. Dyspepsia Causes

sampling from a Bing search on the term "Dyspepsia Causes." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Dyspepsia (C0013395) Definition (MEDLINEPLUS) Nearly everyone has had indigestion at one time. It's a feeling of discomfort or a burning feeling in your upper abdomen. You may have or belch and feel bloated. You may also feel nauseated, or even throw up. You might get indigestion from eating too much or too (...) fast, eating high-fat foods, or eating when you're stressed. Smoking, drinking too much alcohol, using some medicines, being tired, and having ongoing stress can also cause indigestion or make it worse. Sometimes the cause is a problem with the digestive tract, like an or . Avoiding foods and situations that seem to cause it may help. Because indigestion can be a sign of a more serious problem, see your health care provider if it lasts for more than two weeks or if you have severe pain or other

2015 FP Notebook

59. Duodenal perforation following esophagogastroduodenoscopy (EGD) with cautery and epinephrine injection for peptic ulcer disease: An interesting case of nonoperative management in the medical intensive care unit (MICU) Full Text available with Trip Pro

Duodenal perforation following esophagogastroduodenoscopy (EGD) with cautery and epinephrine injection for peptic ulcer disease: An interesting case of nonoperative management in the medical intensive care unit (MICU) The utilization of esophagogastroduodenoscopy (EGD) and related procedures continues to rise. Due to this increase in utilization is an inevitable rise in serious complications such as hemorrhage and perforation. One understudied and dreaded complication of EGD causing significant (...) morbidity and mortality is duodenal perforation.We present the case of a 63-year-old male who presented to our institution's emergency room with dyspepsia, melanic stools, tachycardia, and hypotension. Initial laboratory evaluation was significant for severe anemia, lactic acidosis, and acute kidney injury, while CT scan of the abdomen pelvis did not suggest retroperitoneal hematoma or bowel perforation. An emergent EGD was performed which showed multiple bleeding duodenal ulcers that were cauterized

2015 International journal of surgery case reports

60. An unusual cause of idiopathic megacolon in a juvenile: A case report. Full Text available with Trip Pro

An unusual cause of idiopathic megacolon in a juvenile: A case report. Idiopathic megacolon (IMC) is a rare condition in young children. The association of indigestible food and IMC has never been mentioned in literature.An 11-year-old boy reported with a 1-year duration of intermittent constipation and abdominal distension after having eaten a large amount of fried sticky rice in 1 consumption.Chronic low colonic obstruction, IMC and malnutrition.This patient was managed conservatively for 1 (...) week at first. Then he underwent loop ileostomy since conservative therapy was poorly tolerated. Enteral decompression, gut biopsy, peritoneal lavage, and drainage were performed in the same procedure.Rapid weight gain was observed 4 months after operation.IMC is difficult to diagnose due to the lack of specific clinical manifestations and pathological features. The protocols for management of IMC remains controversial. To achieve a good long-term outcome, early intervention is recommended.

2019 Medicine

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