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Medication Causes of Dyspepsia

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1. Dyspepsia - unidentified cause

and associated stress, anxiety, or depression. Reviewing the person's medication, including drugs that can cause or exacerbate dyspepsia, such as nonsteroidal anti-inflammatory drugs (NSAIDs). Considering an alternative diagnosis. Considering arranging a full blood count, to check for anaemia and/or a raised platelet count, which may suggest underlying malignancy. Initial management of a person with unexplained dyspepsia should include: Offering advice on lifestyle modification. Managing any associated (...) . Alcohol consumption — see the CKS topic on for more information on recommended limits. Assess for stress, anxiety, and depression which may worsen symptoms. See the CKS topics on and for more information. Review the person's medication, and ask about: Any over-the-counter medication such as antacids and/or alginates that have been tried for symptom relief. Drugs that can cause or exacerbate dyspepsia, such as alpha-blockers, anticholinergics, aspirin, benzodiazepines, beta-blockers, bisphosphonates

2018 NICE Clinical Knowledge Summaries

2. Medication Causes of Dyspepsia

Medication Causes of Dyspepsia Medication Causes of Dyspepsia Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Medication Causes (...) of Dyspepsia Medication Causes of Dyspepsia Aka: Medication Causes of Dyspepsia , Gastric Irritants From Related Chapters II. Causes: Gastric Irritants (risks for Peptic Ulcer Disease) S See Coffee and other sources abuse s (e.g. ) III. Causes: Herbal preparations causing Dyspepsia Gingko White willow IV. Causes: Medications causing Dyspepsia ( ) ( ) Antiinflammatory medications s s Cisapride (Propulsid) s ( ) ( ) ( ) s ( ) chloride ( ) V. References Feldman (1998) Sleisenger and Fordtran's GI, p. 106-8

2018 FP Notebook

3. Assessment of dyspepsia

to be individualised. World Gastroenterology Organisation. World Gastroenterology Organisation global guidelines: coping with common GI symptoms in the community. May 2013 [internet publication]. http://www.worldgastroenterology.org/guidelines/global-guidelines/common-gi-symptoms/common-gi-symptoms-english The nomenclature for dyspepsia is confusing. This is largely because some medical organisations include all UGI symptoms in the term dyspepsia, then separate patients with symptoms suggesting GORD (...) for appropriate management, whereas others recognise the overlap in symptoms between the various causes of UGI symptoms but choose to separate the symptoms suggesting GORD before applying the term dyspepsia. Both approaches recommend identifying patients whose symptoms suggest GORD and managing them as having reflux disease. The American College of Gastroenterology and the Canadian Association of Gastroenterology have published joint guidelines for the management of dyspepsia. Moayyedi PM, Lacy BE, Andrews CN

2018 BMJ Best Practice

4. Assessment of dyspepsia

to be individualised. World Gastroenterology Organisation. World Gastroenterology Organisation global guidelines: coping with common GI symptoms in the community. May 2013 [internet publication]. http://www.worldgastroenterology.org/guidelines/global-guidelines/common-gi-symptoms/common-gi-symptoms-english The nomenclature for dyspepsia is confusing. This is largely because some medical organisations include all UGI symptoms in the term dyspepsia, then separate patients with symptoms suggesting GORD (...) for appropriate management, whereas others recognise the overlap in symptoms between the various causes of UGI symptoms but choose to separate the symptoms suggesting GORD before applying the term dyspepsia. Both approaches recommend identifying patients whose symptoms suggest GORD and managing them as having reflux disease. The American College of Gastroenterology and the Canadian Association of Gastroenterology have published joint guidelines for the management of dyspepsia. Moayyedi PM, Lacy BE, Andrews CN

2018 BMJ Best Practice

5. Dyspepsia

of patients might prefer not to take antidepressant medication. In contrast to Statements 5 and 6 above, it should be noted that we recommend TCA before prokinetic for treatment of FD based on the superior evidence for TCA in this indication. STATEMENT 10. WE SUGGEST FUNCTIONAL DYSPEPSIA PATIENTS NOT RESPONDING TO PPI, H. PYLORI ERADICATION THERAPY OR TRICYCLIC ANTIDEPRESSANT THERAPY SHOULD BE OFFERED PROKINETIC THERAPY Conditional recommendation, very low quality evidence Patients with FD oft en have (...) Dyspepsia 988 The American Journal of GASTROENTEROLOGY VOLUME 112 | JULY 2017 www.nature.com/ajg CLINICAL GUIDELINES INTRODUCTION Descriptions of upper gastrointestinal symptoms date back thou- sands of years ( 1 ). “Stomach disorders” became an obsession of developed countries in the eighteenth century ( 2 ) when the term dyspepsia was fi rst coined ( 3 ). A systematic review ( 4 ) reported that ~20% of the population has symptoms of dyspepsia glob- ally. Dyspepsia is more common in women

2017 Canadian Association of Gastroenterology

6. Management of Dyspepsia

) ( 72 ) and a signifi cant propor- tion of patients might prefer not to take antidepressant medication. In contrast to Statements 5 and 6 above, it should be noted that we recommend TCA before prokinetic for treatment of FD based on the superior evidence for TCA in this indication. STATEMENT 10. WE SUGGEST FUNCTIONAL DYSPEPSIA PATIENTS NOT RESPONDING TO PPI, H. PYLORI ERADICATION THERAPY OR TRICYCLIC ANTIDEPRESSANT THERAPY SHOULD BE OFFERED PROKINETIC THERAPY Conditional recommendation, very low (...) Management of Dyspepsia 1 © 2017 by the American College of Gastroenterology The American Journal of GASTROENTEROLOGY CLINICAL GUIDELINES INTRODUCTION Descriptions of upper gastrointestinal symptoms date back thou- sands of years ( 1 ). “Stomach disorders” became an obsession of developed countries in the eighteenth century ( 2 ) when the term dyspepsia was fi rst coined ( 3 ). A systematic review ( 4 ) reported that ~20% of the population has symptoms of dyspepsia glob- ally. Dyspepsia is more

2017 American College of Gastroenterology

7. Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management

immediately (on the same day) to a specialist. [2004] [2004] (Also see acute upper gastrointestinal bleeding [NICE clinical guideline 141].) 1.3.2 Review medications for possible causes of dyspepsia (for example, calcium antagonists, nitrates, theophyllines, bisphosphonates, corticosteroids and non- steroidal anti-inflammatory drugs [NSAIDs]). In people needing referral, suspend NSAID use. [2004] [2004] 1.3.3 Think about the possibility of cardiac or biliary disease as part of the differential diagnosis (...) medication and rare causes such as Zollinger–Ellison syndrome or Crohn's disease. [2004] [2004] 1.7.9 If symptoms recur after initial treatment, offer a PPI to be taken at the lowest dose possible to control symptoms. Discuss using the treatment on an 'as- needed' basis with people to manage their own symptoms. [2004, amended [2004, amended 2014] 2014] 1.7.10 Offer H 2 RA therapy if there is an inadequate response to a PPI. [2004] [2004] 1.8 Interventions for functional dyspepsia 1.8.1 Manage

2014 National Institute for Health and Clinical Excellence - Clinical Guidelines

8. Dyspepsia Causes

Dyspepsia Causes Dyspepsia Causes Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Dyspepsia Causes Dyspepsia Causes Aka: Dyspepsia (...) sampling from a Bing search on the term "Dyspepsia Causes." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Dyspepsia (C0013395) Definition (MEDLINEPLUS) Nearly everyone has had indigestion at one time. It's a feeling of discomfort or a burning feeling in your upper abdomen. You may have or belch and feel bloated. You may also feel nauseated, or even throw up. You might get indigestion from eating too much or too

2018 FP Notebook

9. Dyspepsia - proven peptic ulcer

updated in line with NICE guideline, 2019 update, Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management [ ]. October 2018 — minor update. Adverse effects updated within prescribing information - metronidazole. September 2017 — minor update. SPC update on quinolones to align all CKS topics prescribing advice. Prostatitis - chronic, Gonorrhoea, Pyelonephritis, Diarrhoea - prevention and advice for travellers, Dyspepsia - unidentified cause, Dyspepsia - proven functional (...) NSAIDs are offered full-dose PPI or H 2 RA for 4–8 weeks. Audit criterion 15. People with previous peptic ulcer for whom continuation of NSAID is necessary and are receiving a NSAID are prescribed a PPI. Audit criterion 16. In people with an unhealed peptic ulcer, the following are excluded: Non-adherence. Malignancy. Failure to detect H. pylori . Inadvertent NSAID use. Other ulcer-inducing medication. Rare causes such as Zollinger-Ellison syndrome or Crohn's disease. Audit criterion 17. If symptoms

2018 NICE Clinical Knowledge Summaries

10. Dyspepsia - proven functional

-prandial distress syndrome, where there is post-prandial fullness or early satiety. The cause of functional dyspepsia remains uncertain and is likely to be multifactorial. If left untreated, at least 70% of people with functional dyspepsia will have persistent symptoms one year after diagnosis, and the lifetime risk of recurrence is about 50%. Initial management of functional dyspepsia includes: Offering advice on lifestyle measures that may improve symptoms. Assessing for stress, anxiety (...) — minor update. SPC update on quinolones to align all CKS topics prescribing advice. Prostatitis – chronic, Gonorrhoea, Pyelonephritis, Diarrhoea – prevention and advice for travellers, Dyspepsia – unidentified cause, Dyspepsia – proven functional, Dyspepsia – proven peptic ulcer, Diverticular disease, Gastroenteritis and Scrotal pain and swellings. March to April 2017 — reviewed. A literature search was conducted in February 2017 to identify evidence-based guidelines, UK policy, systematic reviews

2018 NICE Clinical Knowledge Summaries

11. Dyspepsia - proven GORD

and anxiety The recommendation on assessing for and managing associated stress and anxiety is extrapolated from the NICE recommendation to offer psychological treatments to people with functional (non-ulcer) dyspepsia, as this may reduce symptoms in the short-term [ ]. This is also supported by expert opinion in a review article on dyspepsia [ ]. Reviewing the person's medication The recommendation on considering reducing or stopping a variety of drugs that may reduce LOS pressure and cause or exacerbate (...) Dyspepsia - proven GORD Dyspepsia - proven GORD - NICE CKS Share Dyspepsia - proven GORD: Summary The term 'dyspepsia' is used to describe a complex of upper gastrointestinal tract symptoms which are typically present for four or more weeks, including upper abdominal pain or discomfort, heartburn, acid reflux, nausea and/or vomiting. Gastro-oesophageal reflux disease (GORD) is usually a chronic condition where there is reflux of gastric contents back into the oesophagus, causing predominant

2017 NICE Clinical Knowledge Summaries

12. Dyspepsia - pregnancy-associated

on . Treatments already tried, especially over-the-counter medication (for example antacids). Examination is usually normal. Investigations are generally not necessary. Where they are required, they are usually carried out in secondary care and may include: Manometry and pH probes. An upper GI endoscopy. Non-invasive testing for Helicobacter pylori , which may be delayed until after delivery. Basis for recommendation Basis for recommendation The information that dyspepsia in pregnancy is predominantly caused (...) ) on Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management [ ] and expert opinion in review articles [ ; ]. Exclude alarm features is extrapolated from information in the NICE guideline Suspected cancer: recognition and referral [ ]. Ask about a previous history of dyspepsia or reflux symptoms is based on expert opinion in a review article [ ]. Check for aggravating factors is based on expert opinion in a review article [ ] (checking for use of medications which may cause

2017 NICE Clinical Knowledge Summaries

13. The role of endoscopy in dyspepsia

drugs, a trial of antispasmodics, dietary and lifestyle changes, prokinetic agents, sucralfate, simethicone, tricyclic antidepressants, selective serotonin reuptake inhibitors, and cognitive behavior therapy. 51,52 More research is required to under- stand the pathophysiology of symptoms in these patients and the role of medications and other therapies. Other conditions that may cause upper abdominal pain or discomfort (which may be confused with dyspepsia) should be considered, including irritable (...) : (1) postprandial fullness, (2) early satiety, and (3) epigastric pain or burning. The symptoms of dyspepsia overlap signi?cantly with those associated with peptic ulcer disease (PUD), GERD, otherfunctionaldisorderssuchasepigastricpainsyndrome and irritable bowel syndrome, malignancy, adverse effects of medications, pancreatitis, biliary tract disease, vascular disease, and motility disorders. The prevalence of GERD and irritable bowel syndrome is higher in patients with dyspepsia compared

2015 American Society for Gastrointestinal Endoscopy

14. Carbon-13 Urea Breath Test for Helicobacter Pylori Infection in Patients With Uninvestigated Ulcer-Like Dyspepsia

Determinants 9 Carbon-13 Urea Breath Test for Helicobacter Pylori Infection in Patients with Uninvestigated Ulcer-Like Dyspepsia: OHTAC Recommendation. October 2013; pp. 1-10 5 Background An evidence-based analysis (http://www.hqontario.ca/en/documents/eds/2013/full-report-urea-breath-test.pdf) was conducted by the Medical Advisory Secretariat Collaboration to answer the following research question: ? What is the diagnostic accuracy and clinical utility of the carbon-13 urea breath test ( 13 C UBT (...) and no alarm features. In head-to-head comparisons with serology, 13 C UBT has comparable sensitivity but higher specificity (GRADE: Low) Safety No safety concerns were identified Burden of Illness Dyspepsia is a common condition reported by 29% of Canadians. Helicobacter pylori is one of the causes of dyspepsia. The estimated prevalence of H. pylori infection in Ontario is 23%, with older people and immigrants at higher risk. Approximately one third of patients presenting to primary care with dyspepsia

2013 Health Quality Ontario

15. Effect of Gingest on Symptoms of Dyspepsia

in order to exclude the presence of structural or biochemical causes of dyspepsia. Participants are asked to avoid all foods containing ginger within the 14 days prior to study product administration and throughout the study. A list of foods high in ginger will be provided to subjects as a guide and this list will be reviewed at each visit. Subject with known allergy to components of the test product Any medical condition deemed exclusionary by the Principal Investigator Subject has a history of drug (...) of sensation and movement (peristalsis) in the upper digestive tract. A diagnosis of functional dyspepsia is determined when there is no evidence of structural disease and there have been at least three months of one or more of the following (with onset at least six months earlier). Ginger (Zingiber officinale) is traditionally used to treat a number of medical conditions, including those affecting the digestive tract, such as dyspepsia, flatulence, nausea and abdominal pain. Recent human clinical studies

2018 Clinical Trials

16. Visceral Manipulation Treatment to Patients With Non-specific Neck Pain With Functional Dyspepsia

of the first thoracic vertebra, without association with any specific systemic disease provided by multifactorial and/or little known causes. Objective: The objective of the present study will be to verify the clinical effects of MV through visceral nociceptive inhibition in NS-NP patients with functional dyspepsia. Methods: In this study sixty NS-NP patients with functional dyspepsia (age: 18 and 50 years) will be randomized in into two groups: visceral manipulation group (VMG) (n =30) and control group (...) Visceral Manipulation Treatment to Patients With Non-specific Neck Pain With Functional Dyspepsia Visceral Manipulation Treatment to Patients With Non-specific Neck Pain With Functional Dyspepsia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2017 Clinical Trials

17. Effectiveness of Once-daily Dose Regimen of 7-day and 14-day High Dose Rabeprazole-levofloxacin Based Quadruple Therapy for H. Pylori Eradication in Thai Patients With Non-ulcer Dyspepsia

Effectiveness of Once-daily Dose Regimen of 7-day and 14-day High Dose Rabeprazole-levofloxacin Based Quadruple Therapy for H. Pylori Eradication in Thai Patients With Non-ulcer Dyspepsia Effectiveness of Once-daily Dose Regimen of 7-day and 14-day High Dose Rabeprazole-levofloxacin Based Quadruple Therapy for H. Pylori Eradication in Thai Patients With Non-ulcer Dyspepsia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration (...) or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effectiveness of Once-daily Dose Regimen of 7-day and 14-day High Dose Rabeprazole-levofloxacin Based Quadruple Therapy for H. Pylori Eradication in Thai Patients With Non-ulcer Dyspepsia The safety and scientific validity of this study is the responsibility of the study sponsor

2017 Clinical Trials

18. Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study. (PubMed)

Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study. Functional dyspepsia (FD) is a constellation of epigastric symptoms originating in the gastroduodenal region without organic and metabolic cause. However, similar confounding symptoms can also appear in patients with gallbladder (GB) dyskinesia. Therefore, symptoms of GB dyskinesia may be mistaken for FD. We aimed to identify GB dyskinesia as a cause of FD symptoms compatible (...) with the Rome IV criteria and the need for an evaluation of GB function in patients with FD symptoms.We investigated information of patients with FD symptoms who underwent a quantitative Tc-diisoproyl iminodiacetic acid cholescintigraphy (DISIDA scan) through electronic medical records, and GB dyskinesia was judged to be the cause of the FD symptoms if the symptoms disappeared as GB function normalized on the follow-up DISIA scan in patient with decreased GB function on the initial DISIDA scan.A total

Full Text available with Trip Pro

2017 Medicine

19. Trial to Reduce Inappropriate Oesophagogastroduodenoscopies for Dyspepsia

: The Netherlands Organisation for Health Research and Development Maastricht University Medical Center Canisius-Wilhelmina Hospital VieCuri Medical Centre Information provided by (Responsible Party): Radboud University Study Details Study Description Go to Brief Summary: Indigestion or dyspepsia is highly prevalent worldwide. Often these symptoms are of benign nature and subside without treatment, or with lifestyle interventions like dietary modifications. Too often, gastroscopy is performed because (...) Dyspepsia Indigestion Device: e-learning Not Applicable Detailed Description: Rationale: Upper gastrointestinal (GI) symptoms, such as dyspepsia without alarm symptoms, are highly prevalent in the general population. Lifestyle modifications and medication can reduce symptoms in most patients. Guidelines state that oesophagogastroduodenoscopy (OGD) is only indicated in a selected high risk group. In spite of these guidelines, OGD referrals for dyspepsia without alarm symptoms are still substantial

2017 Clinical Trials

20. Medication Causes of Dyspepsia

Medication Causes of Dyspepsia Medication Causes of Dyspepsia Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Medication Causes (...) of Dyspepsia Medication Causes of Dyspepsia Aka: Medication Causes of Dyspepsia , Gastric Irritants From Related Chapters II. Causes: Gastric Irritants (risks for Peptic Ulcer Disease) S See Coffee and other sources abuse s (e.g. ) III. Causes: Herbal preparations causing Dyspepsia Gingko White willow IV. Causes: Medications causing Dyspepsia ( ) ( ) Antiinflammatory medications s s Cisapride (Propulsid) s ( ) ( ) ( ) s ( ) chloride ( ) V. References Feldman (1998) Sleisenger and Fordtran's GI, p. 106-8

2015 FP Notebook

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