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McMurray Test

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201. Management of Arterial Hypertension

) Abnormal glucose tolerance test Obesity [BMI =30 kg/m 2 (height 2 )] Abdominal obesity (waist circumference: men =102 cm; women =88 cm) (in Caucasians) Family history of premature CVD (men aged 3.5 mV; RaVL >1.1 mV; Cornell voltage duration product >244 mV*ms), or Echocardiographic LVH [LVM index: men >115 g/m 2 ; women >95 g/m 2 (BSA)] a Carotid wall thickening (IMT >0.9 mm) or plaque Carotid–femoral PWV >10 m/s Ankle-brachial index 7% (53 mmol/mol), and/or Post-load plasma glucose >11.0 mmol/L (198

2013 European Society of Cardiology

202. Management of Stable Coronary Artery Disease

investigations . . . . . . . . . . . . . . .2958 6.2.1 Basic testing . . . . . . . . . . . . . . . . . . . . . . . . . . .2958 6.2.1.1 Biochemical tests (see web addenda) . . . . . . . . .2958 6.2.1.2 Resting electrocardiogram . . . . . . . . . . . . . . . .2960 6.2.1.3 Echocardiography at rest (see web addenda) . . . .2960 6.2.1.4 Cardiac magnetic resonance at rest . . . . . . . . . . .2960 6.2.1.5 Ambulatory electrocardiogram monitoring . . . . . .2961 6.2.1.6 Chest X-ray (...) . . . . . . . . . . . . . . . . . . . . . . . . .2961 6.2.2 Three major steps used for decision-making . . . . . .2961 6.2.3 Principles of diagnostic testing . . . . . . . . . . . . . . .2961 6.2.4 Stress testing for diagnosing ischaemia . . . . . . . . . .2963 6.2.4.1 Electrocardiogram exercise testing . . . . . . . . . . .2963 6.2.4.2 Stress imaging (see web addenda) . . . . . . . . . . . .2965 6.2.4.2.1 Stress echocardiography . . . . . . . . . . . . . .2965 6.2.4.2.2 Myocardial perfusion scintigraphy (single photon emission computed

2013 European Society of Cardiology

203. Diabetes, Pre-Diabetes and Cardiovascular Diseases

dinucleotide phosphate hydrogen NDR National Diabetes Register NHANES NationalHealth and NutritionExamination Survey ESC Guidelines 3038 Downloaded from https://academic.oup.com/eurheartj/article-abstract/34/39/3035/503593 by guest on 02 April 2019NICE National Institute for Health and Clinical Excel- lence (UK) NNT number needed to treat NO nitric oxide NOAC new oral anticoagulants NYHA New York Heart Association OAT Occluded Artery Trial OGTT oral glucose tolerance test OMT optimal medical treatment (...) Health Organization (WHO) and the American Diabetes Associ- ation (ADA). 2– 6 Glycated haemoglobin A 1c (HbA 1c ) has been recommended as a diagnostic test for DM, 7,8 but there remain con- cerns regarding its sensitivity in predicting DM and HbA 1c values ,6.5% do not exclude DM that may be detected by blood glucose measurement, 7 –10 as further discussed in Section 3.3. Four main aetiological categories of DM have been identi?ed: type 1 diabetes (T1DM), T2DM, ‘other speci?c types’ of DM

2013 European Society of Cardiology

204. Knee pain - assessment

. The McMurray test for meniscal injuries is no longer recommended because of concerns that it exacerbates the injury and its low diagnostic accuracy. Assess for neurovascular damage, including loss of sensation or weakness in the lower leg or foot, absence or asymmetry of pulses, or acute compartment syndrome. Basis for recommendation Basis for recommendation General knee examination recommendations are based on expert opinion in review articles [ ; ], a BMJ Best Practice review [ ] and a textbook (...) to rule in or out a knee disorder [ ]. The Lachman test was found to be an accurate test to rule in or out an anterior cruciate ligament injury [ ], although another systematic review found it to have decreased sensitivity, particularly for partial ruptures [ ]. Expert opinion is that using a combination of tests may be more accurate [ ; ]. The recommendation that the McMurray test is not recommended for meniscal injuries is based on expert opinion from several CKS reviewers that this test can

2017 NICE Clinical Knowledge Summaries

205. Findings series 41 - Public health implications of the pSoBid study

, participants completed lifestyle and psychological questionnaires and underwent measurement of blood pressure, heart rate, hip, waist and mid-thigh circumference and assessment of lung function. At visit 2, participants were asked to fast before attending, so bloods could be taken for biochemical analyses. Height and weight were measured. After being provided with breakfast, subjects completed a number of cognitive tests. Finally, carotid artery ultrasound, a non-invasive measure of atherosclerosis (...) 21 , the Rosenberg Self-esteem Scale 22 and the Eysenck Personality Questionnaire 23 . A series of cognitive tests were completed and included the Trail Making Test 24 , the Stroop Test 25 , the Choice Reaction Time Test 26 , the Auditory Verbal Learning Test 27 and the National Adult Reading Test 28 . b Magnetic resonance imaging (MRI) is a medical imaging technique most commonly used to visualise detailed internal body structures that do not show up well on x-rays. Public health implications

2014 Glasgow Centre for Population Health

206. Electrocardiograms for Diagnosing Ischemia as a Precipitant to Acute Heart Failure

) McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2012 Jul;33(14):1787-847. (7) National Institute for Health and Clinical Excellence. Chest pain of recent onset (...) : description of population. Eur Heart J. 2006 Nov;27(22):2725-36. (10) Davenport C, Cheng EY, Kwok YT, Lai AH, Wakabayashi T, Hyde C et al. Assessing the diagnostic test accuracy of natriuretic peptides and ECG in the diagnosis of left ventricular systolic dysfunction: a systematic review and meta-analysis. Br J Gen Pract. 2006 Jan;56(522):48-56. (11) Jneid H, Anderson JL, Wright RS, Adams CD, Bridges CR, Casey DE, Jr. et al. 2012 ACCF/AHA focused update of the guideline for the management of patients

2012 Health Quality Ontario

207. Inotropic and Vasoactive Agents for In-Hospital Heart Failure Management

: Literature Search Strategies 14 Appendix 2: GRADE Tables 16 References 17 . Inotropic and Vasoactive Agents for In-Hospital Heart Failure Management: A Rapid Review. December 2012; pp. 1–19. 5 List of Abbreviations AMSTAR Assessment of Multiple Systematic Reviews CI Confidence interval(s) HF Heart failure M-H Mantel-Haenszel test NYHA New York Heart Association RCT Randomized controlled trial RR Relative risk . Inotropic and Vasoactive Agents for In-Hospital Heart Failure Management: A Rapid Review (...) Management: A Rapid Review. December 2012; pp. 1–19. 17 References (1) Nohria A, Lewis E, Stevenson LW. Medical management of advanced heart failure. JAMA. 2002 Feb 6;287(5):628-40. (2) Metra M, Ponikowski P, Dickstein K, McMurray JJ, Gavazzi A, Bergh CH et al. Advanced chronic heart failure: a position statement from the Study Group on Advanced Heart Failure of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2007 Jun;9(6-7):684-94. (3) Gheorghiade M, Abraham WT

2012 Health Quality Ontario

208. ROCKET?AF: Rivaroxaban vs Warfarin in patients with Atrial Fibrillation

15mg* po daily versus dose-adjusted warfarin (INR 2-3 in patients <70 years of age & INR 1.6-2.6 in patients =70 years old). *rivaroxaban 10mg po daily in patients with CrCl 30-49 mL/min ? 22% of the patient population ? Safety: rivaroxaban was non-inferior to warfarin for the composite of major & non-major bleeding; individual composite endpoints not statistically significant when separated. Differences in location of bleeds were not tested for statistical significance. ? Efficacy: not powered (...) ://www.nejm.org/doi/full/10.1056/NEJMoa1009638 (ROCKET-AF) 2 Granger CB, Alexander JH, McMurray JJV et al. Apixaban versus Warfarin in Patients with Atrial Fibrillation. N Engl J Med August 28, 2011 http://www.nejm.org/doi/pdf/10.1056/NEJMoa1107039 (ARISTOTLE) 3 Jin M. RxFiles Trial Summary – ARISTOTLE: Apixaban versus warfarin in patients with atrial fibrillation. Saskatoon, SK: RxFiles; 2011. Available from: www.rxfiles.ca. Accessed April 30 th , 2012. 4 Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran

2012 RxFiles

209. Acute Myocardial Infarction in patients presenting with ST-segment elevation

on sound evidence, derived from well-conducted clinical trials. Because of the great number of trials on new treatments performed in recent years, and in view of new diagnostic tests, the ESC decided that it was opportune to upgrade the previous guidelines and appointed a Task Force. It must be recognized that, even when excellent clinical trials have been undertaken, their results are open to interpretation and that treatment options may be limited by resources. Indeed, cost-effectiveness is becoming (...) .) thrombolysis. A positive point-of-care troponin test 1–2 h after symptom onset in patients with BBB of uncertain origin may help decide whether to perform emergency angiog- raphy with a view to primary PCI. Patients with myocardial in- farction and RBBB also have a poor prognosis, 25 although RBBB usually will not hamper interpretation of ST-segment ele- vation. Prompt management should be considered when per- sistent ischaemic symptoms occur in the presence of RBBB, regardless of whether or not the latter

2012 European Society of Cardiology

210. CVD Prevention in clinical practice

McMurray (UK), Andrzej Paja ?k (Poland), Alexander Parkhomenko (Ukraine), Loukianos Rallidis (Greece), Fausto Rigo (Italy), Evangelista Rocha (Portugal), Luis Miguel Ruilope (Spain), Enno van der Velde (The Netherlands), Diego Vanuzzo (Italy), Margus Viigimaa (Estonia), Massimo Volpe (Italy), Olov Wiklund (Sweden), Christian Wolpert (Germany). The disclosure forms of the authors and reviewers are available on the ESC website www.escardio.org/guidelines Societies: 1 European Society of Cardiology (ESC

2012 European Society of Cardiology

211. Acute and Chronic Heart Failure

Acute and Chronic Heart Failure ESC GUIDELINES ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC Authors/Task Force Members: John J.V. McMurray (Chairperson) (UK) * , Stamatis Adamopoulos (Greece), Stefan D. Anker (Germany), Angelo Auricchio (Switzerland (...) ), Antonio Coca (Spain), Peter Cowburn (UK), Henry Dargie (UK), Perry Elliott (UK), Frank Arnold Flachskampf (Sweden), Guido Francesco Guida (Italy), Suzanna Hardman (UK), Bernard Iung * Corresponding author. Chairperson: Professor John J.V. McMurray, University of Glasgow G12 8QQ, UK. Tel:+44 141 330 3479, Fax:+44 141 330 6955, Email: john.mcmurray@ glasgow.ac.uk Other ESC entities having participated in the development of this document: Associations: European Association for Cardiovascular Prevention

2012 European Society of Cardiology

212. Atrial Fibrillation

patients), or (iii) to short-term antiarrhyth- mic drug therapy limited to four weeks after cardioversion (261 patients). The trial tested the hypothesis that short-term therapy was non-inferior to long-term therapy. Patients were fol- lowed for six months by daily telemetric ECG recording for the primary outcome of persistent AF or death. The trial demon- strated that short-term therapy conveyed a slightly inferior—but still effective—antiarrhythmic action, estimated at 80% of the effect of long-term (...) and prevention of remodelling – ACEI/ARB/statin HHD No LVH LVH sotalol dronedarone dronedarone amiodarone amiodarone CHD HF Figure 4 Choice of antiarrhythmic drug according to underlying pathology. ESC Guidelines 2738 Downloaded from https://academic.oup.com/eurheartj/article-abstract/33/21/2719/493051 by guest on 02 April 2019Dronedarone has been associated with severe hepatotoxicity in a few instances. Hence, monitoring of liver function tests is advisable in patients on long-term dronedarone treatment

2012 European Society of Cardiology

213. Valvular Heart Disease

. . . . . . . . . . . . . . . . . . . . . . . . .2455 3.1.1. Clinical evaluation . . . . . . . . . . . . . . . . . . . . . .2455 3.1.2. Echocardiography . . . . . . . . . . . . . . . . . . . . . .2456 3.1.3. Other non-invasive investigations . . . . . . . . . . . .2456 3.1.3.1. Stress testing . . . . . . . . . . . . . . . . . . . . . .2456 3.1.3.2. Cardiac magnetic resonance . . . . . . . . . . . .2457 3.1.3.3. Computed tomography . . . . . . . . . . . . . . .2457 3.1.3.4. Fluoroscopy . . . . . . . . . . . . . . . . . . . . . . .2458 3.1.3.5 (...) . . . . . . . . . . . . . . . . . . . . . . . . .2460 4.4. Indications for surgery . . . . . . . . . . . . . . . . . . . . . .2461 4.5. Medical therapy. . . . . . . . . . . . . . . . . . . . . . . . . . .2462 4.6. Serial testing . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2463 4.7. Special patient populations . . . . . . . . . . . . . . . . . . .2463 5. Aortic stenosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2463 5.1. Evaluation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2463 5.2. Natural history

2012 European Society of Cardiology

214. 3D-MRI combined with signal-to-noise ratio measurement can improve the diagnostic accuracy and sensitivity in evaluating meniscal healing status after meniscal repair. (Abstract)

, swelling, locking, or positive McMurray test; on MRI, grade III signal intensity at the site of repair. Finally, the SNR on 3D-MRI of the healed and the unhealed groups were compared.On second-look arthroscopy, 68 (90.7%) menisci were found to be completely healed. With the arthroscopic healing rate as the standard, the clinical healing rate was 69.3% (63 menisci) [sensitivity, 85.7%; specificity, 75.0%; accuracy, 76.0%; positive predictive value (PPV), 26.1%; negative predictive value (NPV), 98.1

2018 Knee Surgery, Sports Traumatology, Arthroscopy

215. Ketamine Versus Electroconvulsive Therapy in Depression

subjects of childbearing potential must have a negative urine pregnancy test at enrolment (Visit 1) and be willing to use a reliable method of birth control (i.e., double-barrier method, oral contraceptive, implant, dermal contraception, long-term injectable contraceptive, intrauterine device, or tubal ligation) during the study. Abstain from consuming grapefruit juice (a potent 3A4 cytochrome inhibitor) on the day of the ketamine infusions as it may slow down the elimination of ketamine. Be able (...) function tests AST and ALT three times the upper normal limit at screening. Uncorrected hypothyroidism or hyperthyroidism. Subjects needing a thyroid hormone supplement to treat hypothyroidism must have been on a stable dose of the medication for 30 days prior to enrolment (Visit 1). Clinically significant deviation from the reference range in clinical laboratory test results as judged by the investigator(s). Including: Sodium under 135 or over 145 mmol/L Potassium under 3.5 or over 5.0 mmol/L Chloride

2018 Clinical Trials

216. Impact of Body Mass Index on the Accuracy of N-Terminal Pro-Brain Natriuretic Peptide and Brain Natriuretic Peptide for Predicting Outcomes in Patients With Chronic Heart Failure and Reduced Ejection Fraction: Insights From the PARADIGM-HF Study (Prospect (Full text)

Medical Center, Charleston (M.R.Z.); Institut de Cardiologie de Montréal, Université de Montréal, Canada (J.L.R.); Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden (K.S.); and Novartis Pharmaceuticals Corporation, East Hanover, NJ (M.L., V.C.S., M.F.P.). McMurray John J JJ From Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (W.N., B.L.C., A.S.D., S.D.S.); Department of Internal Medicine, University of Campinas, Campinas, Brazil (W.N.); British Heart (...) Fragments blood Predictive Value of Tests Prospective Studies Protease Inhibitors adverse effects therapeutic use Risk Assessment Risk Factors Stroke Volume drug effects Time Factors Treatment Outcome Ventricular Function, Left drug effects BNP NT-proBNP heart failure natriuretic peptides obesity prognosis 2016 11 30 6 0 2016 11 30 6 0 2018 8 28 6 0 ppublish 27895026 CIRCULATIONAHA.116.024976 10.1161/CIRCULATIONAHA.116.024976

2018 Circulation Controlled trial quality: uncertain PubMed abstract

217. Clinical Practice Guideline on the Management of Anterior Cruciate Ligament Injuries

for or against the intervention. Moderate Moderate Evidence from two or more “Moderate” strength studies with consistent findings, or evidence from a single “High” quality study for recommending for or against the intervention. Limited Low Strength Evidence or Conflicting Evidence Evidence from two or more “Low” strength studies with consistent findings or evidence from a single study for recommending for or against the intervention or diagnostic test or the evidence is insufficient or conflicting and does (...) that the practitioner might perform surgical reconstruction because it reduces activity related disability and recurrent instability which may lead to additional injury. Strength of Recommendation: Limited Description: Evidence from two or more “Low” strength studies with consistent findings or evidence from a single study for recommending for or against the intervention or diagnostic test or the evidence is insufficient or conflicting and does not allow a recommendation for or against the intervention. ACL YOUNG

2014 American Academy of Orthopaedic Surgeons

218. Home Modifications and Their Impact on Waged Care Substitution

of the key definitions and concepts underpinning waged home care substitution by home modifications, and then testing this by comparing outcome and process measures from cases—those with exposure to home modification and waged home care interventions. Thus we systematically search the literature to present both current work and then use this to refine and advance a person-environment fit theory relevant to waged home care substitution, collect cases to test it, and reflect on whether the theory (...) its real-life context, from which both generating and testing hypotheses become possible. The case study method was deemed an ideal supplementary methodology for this research because of its ability to describe and illustrate a complex situation. This report seeks to better understand the substitutive relationships that can develop surrounding care in the home, where health, available care support and degree of home modifications are all highly individualised and each come into play to varying

2014 Home Modification Information Clearinghouse

219. Evaluation and Treatment of Functional Constipation in Infants and Children: Evidence-Based Recommendations from ESPGHAN and NASPGHAN

after 2-4 weeks 6 7 9 16 17 20 22 24 25 27 26 23 18 19 21 15 14 11 13 12 8 5 4 23 10 1 Alarm signs/ symptoms? Tailor testing for differential diagnosis Continue therapy Consider hypo- allergic formula for 2-4 weeks Response? Reconsider organic diseases No No No No No No No No No No No No No No No No No No No No No No No No No No No Yes Y es Yes Yes Y es Yes Yes Y es Yes Yes Y es Yes Yes Y es Yes Yes Y es Yes Yes Y es Yes Yes Y es Yes Yes Y es Yes Yes Y es Yes Yes Y es Yes FIGURE 1. Algorithm (...) previous treatment been sufficient? Alarm signs/ symptoms? Normal results? Tailor testing for differential diagnosis Treat accordingly Intractable constipation Constipation confirmed? Consultation with mental health care Maintenance therapy Colonic transit time study to confirm constipation Doubts about the diagnosis of constipation? Colonic manometry (Rule out colonic neuro muscular disorders) Consider:  Mental health care  Biofeedback  ACE  Botox  SNS  TENS Consider:  Surgery  SNS  TENS

2014 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

220. 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary

since 1980. The ACC/AHA Task Force on Practice Guidelines (Task Force) directs this effort by developing, updating, and revising practice guidelines for cardiovascular diseases and procedures. Experts in the subject under consideration are selected from both ACC and AHA to examine subject-speci?c data and write guidelines. Writing committees are spe- ci?cally charged with performing a literature review; weighing the strength of evidence for or against particular tests, treatments, or procedures (...) ; and including estimates of expected health outcomes where such data exist. Patient- speci?c modi?ers, comorbidities, and issues of patient preference that may in?uence the choice of tests or ther- apies are considered, as well as frequency of follow-up and cost effectiveness. When available, information from studies on cost is considered; however, a review of data on ef?cacy and outcomes constitutes the primary basis for preparing recommendations in this guideline. In analyzing the data and developing

2014 Society for Cardiovascular Angiography and Interventions

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