How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

23,302 results for

Marijuana

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Cannabis and psychosis: revisiting a nineteenth century study of 'Indian Hemp and Insanity' in Colonial British India. (Abstract)

Cannabis and psychosis: revisiting a nineteenth century study of 'Indian Hemp and Insanity' in Colonial British India. In nineteenth-century British India, concern regarding large numbers of asylum patients with 'Indian Hemp Insanity' led to establishment of the Indian Hemp Drugs Commission. The exotic cannabis plant was widely used in pharmacopeia and a source of government revenue. The Commission was tasked with determining the public health risks of cannabis use, particularly mental illness (...) . This analysis of the Commission report seeks to highlight the status of 1892 cannabis research and compare it with current evidence for medical and recreational cannabis use.Detailed historiographic review of the Indian Hemp Drugs Commission Report (1892).In 1892, heavy cannabis use was considered to have been associated with severe mental illness (7.3% of asylum patients; 12.6% of patients with diagnoses). About two-thirds were children and young adults with higher relapse rates. Risk increased with early

2019 Psychological Medicine

2. Edible Cannabis, Cannabis Extracts and Cannabis Topicals: A Primer on the New Cannabis Products

Edible Cannabis, Cannabis Extracts and Cannabis Topicals: A Primer on the New Cannabis Products Edible Cannabis, Cannabis Extracts and Cannabis Topicals: A Primer on the New Cannabis Products | Canadian Centre on Substance Use and Addiction Search the CCSA website Search Substances and Addiction SPOTLIGHT Health and Public Safety SPOTLIGHT People and Communities SPOTLIGHT Data Trends SPOTLIGHT About Us SPOTLIGHT Menu Search the CCSA website Search Substances and Addiction SPOTLIGHT Health (...) and Public Safety SPOTLIGHT People and Communities SPOTLIGHT Data Trends SPOTLIGHT About Us SPOTLIGHT Breadcrumb Edible Cannabis, Cannabis Extracts and Cannabis Topicals: A Primer on the New Cannabis Products Share Topic Summary Edible Cannabis, Cannabis Extracts and Cannabis Topicals: A Primer on the New Cannabis Products Publication date: 2019 Author: Canadian Centre on Substance Use and Addiction Provides an overview of edible cannabis products, cannabis extracts and topical cannabis products

2019 Canadian Centre on Substance Abuse

3. Edible Cannabis, Cannabis Extracts and Cannabis Topicals: A Primer on the New Cannabis Products

cannabinoid pharmacokinetics. Chemistry and Biodiversity, 4(8), 1770–1804. 4. Grotenhermen, F. (2003). Pharmacokinetics and pharmacodynamics of cannabinoids. Clinical Pharmacokinetics, 42(4), 327–360. 5. Berger, E. (2014). Legal marijuana and pediatric exposure: Pot edibles implicated in spike in child emergency department visits. Annals of Emergency Medicine, 64(4), A19–A21. 6. Potera, C. (2015). Kids and marijuana edibles: A worrisome trend emerges. American Journal of Nursing, 115(9), 15. 7. Alzghari (...) Edible Cannabis, Cannabis Extracts and Cannabis Topicals: A Primer on the New Cannabis Products www.ccsa.ca • www.ccdus.ca Canadian Centre on Substance Use and Addiction • Centre canadien sur les dépendances et l’usage de substances Page 1 Edible Cannabis, Cannabis Extracts and Cannabis Topicals: A Primer on the New Cannabis Products Edible Cannabis (or Edibles) Edible cannabis (or edibles for short) are products containing cannabinoids that you eat or drink. Cannabinoids are chemical compounds

2019 Canadian Centre on Substance Abuse

4. Herbal cannabis and pharmaceutical cannabinoid treatment following motor vehicle accidents: A state of the science review

recommendation) — Nabilone is off-label for pain and has limited evidence of benefit. However, it is less expensive than nabiximols and dosing is more consistent than for smoked cannabis — Nabiximols is expensive and, in some provinces, only available through specialist prescribing or special authorization. However, nabiximols has better evidence than nabilone does -If considering medical cannabinoids, we recommend against medical marijuana (particularly smoked) as the initial product (strong recommendation (...) Herbal cannabis and pharmaceutical cannabinoid treatment following motor vehicle accidents: A state of the science review Herbal cannabis and pharmaceutical cannabinoid treatment following motor vehicle accidents: A state of the science review Final Report Carolyn J Green, PhD Ken L Bassett, MD, PhD Therapeutics Initiative University of British Columbia October 2018 Table of Contents 1.0 Developing a funding policy framework for ICBC insurance claims 1 1.1 Scientific medical knowledge

2020 Therapeutics Letter

5. Cannabinoid-deficient Benin republic hemp (Cannabis sativa L.) improves semen parameters by reducing prolactin and enhancing anti-oxidant status. Full Text available with Trip Pro

Cannabinoid-deficient Benin republic hemp (Cannabis sativa L.) improves semen parameters by reducing prolactin and enhancing anti-oxidant status. Nigerian Cannabis sativa (hemp) causes male gonadotoxicity by inducing hyperprolactinemia, down-regulation of hypothalamic-pituitary-testicular axis, and oxidative stress. Benin republic hemp has been preferred by illicit users in Nigeria but its effect on male fertility is not understood. This study determined and compared the compositions of Benin (...) and in combination with bromocriptine respectively, while groups V and VI received 10 mg/kg BHE alone and in combination with bromocriptine respectively. Comparisons among the groups were done by one-way analysis of variance, followed by post-hoc Tukey multiple comparison test. Statistical significance was considered at p < 0.05.The BHE has no cannabichromene and tetrahydrocannabinol but a very small quantity of cannabinol and higher quantity of fatty acids when compared to Nigerian hemp. Both doses of BHE

2019 BMC Complementary and Alternative Medicine

6. Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical Effectiveness and Guidelines

study were identified regarding the use of medical cannabis or cannabinoids in the treatment of insomnia disorder in adults. Tags cannabidiol, cannabinoids, cannabis, insomnia, marihuana, marijuana, mental health, sleep disorders, sleep initiation and maintenance disorders, sleeplessness, Cannabinoid, insomniac, insomniacs, sleep dysfunction Files Rapid Response Summary of Abstracts Published : June 26, 2017 Related Content Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get (...) Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical Effectiveness and Guidelines Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical Effectiveness and Guidelines Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

7. Clearing the Smoke on Cannabis: Medical Use of Cannabis and Cannabinoids ? An Update

not have the psychoactive effects of THC and appears to have a number of therapeutic benefits. The Endocannabinoid System The cannabinoids produce their effects by binding to cannabinoid receptors that are found throughout the human body. There are two types of cannabinoid receptors that are named CB 1 and CB 2 . The highest concentration of the CB 1 receptor is found in the brain, located on brain 3 • The cannabis plant produces marijuana (cannabis herb) and hashish (cannabis resin). • Cannabinoids (...) for a broad audience, including health professionals, policy makers and researchers. 1 5Clearing the Smoke on Cannabis: Medical Use of Cannabis and Cannabinoids 2 Background After alcohol, cannabis (also referred to as marijuana), is the most widely used psychoactive substance in Canada. According to the 2013 Canadian Tobacco, Alcohol and Drug Use Survey (CTADS), 10.6% of Canadians aged 15 years and older reported using cannabis in the past year (Statistics Canada, 2015), virtually unchanged from 10.2

2016 Canadian Centre on Substance Abuse

8. Correlation of creatinine- and specific gravity-normalized free and glucuronidated urine cannabinoid concentrations following smoked, vaporized, and oral cannabis in frequent and occasional cannabis users. (Abstract)

Correlation of creatinine- and specific gravity-normalized free and glucuronidated urine cannabinoid concentrations following smoked, vaporized, and oral cannabis in frequent and occasional cannabis users. Variability in urine dilution complicates urine cannabinoid test interpretation. Normalizing urine cannabinoid concentrations to specific gravity (SG) or creatinine was proposed to account for donors' hydration states. In this study, all urine voids were individually collected from eight (...) frequent and eight occasional cannabis users for up to 85 hours after each received on separate occasions 50.6 mg Δ9-tetrahydrocannabinol (THC) by smoking, vaporization, and oral ingestion in a randomized, within-subject, double-blind, double-dummy, placebo-controlled protocol. Each urine void was analyzed for 11 cannabinoids and phase I and II metabolites by liquid chromatography-tandem mass spectrometry (LC-MS/MS), SG, and creatinine. Normalized urine concentrations were log10 transformed to create

2019 Drug testing and analysis Controlled trial quality: uncertain

9. Clearing the Smoke on Cannabis: Maternal Cannabis Use during Pregnancy ? An Update

., Sambamoorthi, U., Taylor, P ., Richardson, G., Robles, N., Jhon, Y., . . . & Jasperse, D. (1991). Prenatal marijuana use and neonatal outcome. Neurotoxicology and Teratology, 13(3), 329–334. 10 Clearing the Smoke on Cannabis: Maternal Cannabis Use during Pregnancyde Oliveira Silveira, G., Loddi, S., de Oliveira, C.D.R., Zucoloto, A.D., Fruchtengarten, L.V.G., & Yonamine, M. (2017). Headspace solid-phase microextraction and gas chromatography — mass spectrometry for determination of cannabinoids in human (...) , cannabis (also referred to as marijuana) is the most widely used psychoactive substance in Canada. According to the 2015 Canadian Tobacco, Alcohol and Drugs Survey (CTADS), 12.3% of Canadians aged 15 years and older reported using cannabis at least once in 2015 (Statistics Canada, 2016a), an increase from 10.6% in 2013. The use of cannabis is generally more prevalent among young people, with 20.6% of youth aged 15 to 19 and 29.7% of young adults aged 20 to 24 reporting past-year use in 2015

2018 Canadian Centre on Substance Abuse

10. Chemical characterization, pharmacological effects, and toxicity of an ethanol extract of Celtis pallida Torr. (Cannabaceae) aerial parts. (Abstract)

Chemical characterization, pharmacological effects, and toxicity of an ethanol extract of Celtis pallida Torr. (Cannabaceae) aerial parts. Celtis pallida Torr (Cannabaceae) is employed as a folk medicine for the treatment of inflammation, pain, skin infections, and diarrhea, among other diseases.The purpose of this work was to assess the chemical composition, the in vitro and in vivo toxicity, the antimicrobial, anti-inflammatory, antidiarrheal, antinociceptive, locomotor, and sedative effects

2018 Journal of Ethnopharmacology

11. Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science. (Abstract)

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science. Comprehensive literature reviews of historical perspectives and evidence supporting cannabis/cannabinoids in the treatment of pain, including migraine and headache, with associated neurobiological mechanisms of pain modulation have been well described. Most of the existing literature reports on the cannabinoids Δ9 (...) -tetrahydrocannabinol (THC) and cannabidiol (CBD), or cannabis in general. There are many cannabis strains that vary widely in the composition of cannabinoids, terpenes, flavonoids, and other compounds. These components work synergistically to produce wide variations in benefits, side effects, and strain characteristics. Knowledge of the individual medicinal properties of the cannabinoids, terpenes, and flavonoids is necessary to cross-breed strains to obtain optimal standardized synergistic compositions

2018 Headache

12. Important Legislative and Regulatory Changes Impacting the Commercialization of Cannabis, Hemp, and CBD. (Abstract)

Important Legislative and Regulatory Changes Impacting the Commercialization of Cannabis, Hemp, and CBD. No Abstract Available.

2019 Alternative Therapies in Health & Medicine

13. Cannabis-based medicinal products

technology appraisal guidance on cannabidiol with clobazam for treating seizures associated with Lennox-Gastaut syndrome and Dravet syndrome. Products covered by the guideline include: cannabis-based products for medicinal use as set out by the UK Government in the 2018 Regulations the licensed products delta-9-tetrahydrocannibinol combined with cannabidiol (Sativex) and nabilone plant-derived cannabinoids such as pure cannabidiol (CBD) synthetic compounds which are identical in structure to naturally (...) occurring cannabinoids such as delta-9-tetrahydrocannabinol (THC), for example, dronabinol. Who is it for? Who is it for? Healthcare professionals People taking cannabis-based medicinal products, their families and carers Cannabis-based medicinal products (NG144) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 4 of 27Recommendations Recommendations People have the right to be involved in discussions and make informed

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

14. Clearing the Smoke on Cannabis: Cannabis Use and Driving ? An Update

who are impaired by cannabis. Background After alcohol, cannabis, also referred to as marijuana, is the most widely used psychoactive substance in Canada. According to the 2015 Canadian Tobacco, Alcohol and Drugs Survey (CTADS), 12.3% of Canadians aged 15 years and older reported using cannabis at least once in the past year (Statistics Canada, 2016), significantly higher than the 10.6 in 2013. The use of cannabis is generally more prevalent among youth, with 20.6% of youth aged 15 to 19 and 29.7 (...) is a tobacco-like greenish or brownish material consisting of the dried flowering, fruiting tops and leaves of the cannabis plant, Cannabis sativa. Hashish or cannabis resin is the dried brown or black resinous secretion of the flowering tops of the cannabis plant. The acute effects of cannabis include euphoria and relaxation, changes in perception, time distortion, deficits in attention span and memory, body tremors, and impaired motor functioning. It is a controlled substance under the Controlled Drugs

2017 Canadian Centre on Substance Abuse

15. Canadian guidelines on cannabis use disorder among older adults

of Canada. Health Canada. Information for Health Care Professionals: Cannabis (marihuana, marijuana) and the Cannabinoids. Ottawa, ON: Health Canada; 2018. Retrieved from https://www.canada.ca/content/dam/ hc-sc/documents/services/drugs-medication/cannabis/ information-medical-practitioners/information-health- care-professionals-cannabis-cannabinoids-eng.pdf 13. Hackam DG. Cannabis and stroke: systematic appraisal of case reports. Stroke. 2015;46(3):852–56. 14. Hemachandra D, McKetin R, Cherbuin N, et (...) withdrawal symptoms in older adults, as well as the presentation of can- nabis hyperemesis syndrome. (9) Cannabis is a plant that contains hundreds of com- pounds, including cannabinoids which act on the endogenous cannabinoid (endocannabinoid) system. Certain cannabi- noids act by influencing reward, motivation, and substance- related cues. Notably, delta-9-tetrahydro-cannabinol (THC) and cannabidiol (CBD) are two cannabinoids that have been studied the most. They exert various effects by binding

2020 CPG Infobase

16. Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Full Text available with Trip Pro

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Cannabis sativa produces hundreds of phytocannabinoids and terpenes. Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL), characterized by patches, plaques and tumors. Sézary is a leukemic stage of CTCL presenting with erythroderma and the presence of neoplastic Sézary T-cells in peripheral blood. This study aimed to identify active (...) compounds from whole cannabis extracts and their synergistic mixtures, and to assess respective cytotoxic activity against CTCL cells. Ethanol extracts of C. sativa were analyzed by high-performance liquid chromatography (HPLC) and gas chromatography/mass spectrometry (GC/MS). Cytotoxic activity was determined using the XTT assay on My-La and HuT-78 cell lines as well as peripheral blood lymphocytes from Sézary patients (SPBL). Annexin V assay and fluorescence-activated cell sorting (FACS) were used

2020 Oncotarget

17. The nephrologist's guide to cannabis and cannabinoids. Full Text available with Trip Pro

The nephrologist's guide to cannabis and cannabinoids. Cannabis (marijuana, weed, pot, ganja, Mary Jane) is the most commonly used federally illicit drug in the United States. The present review provides an overview of cannabis and cannabinoids with relevance to the practice of nephrology so that clinicians can best take care of patients.Cannabis may have medicinal benefits for treating symptoms of advanced chronic kidney disease (CKD) and end-stage renal disease including as a pain adjuvant (...) potentially reducing the need for opioids. Cannabis does not seem to affect kidney function in healthy individuals. However, renal function should be closely monitored in those with CKD, the lowest effective dose should be used, and smoking should be avoided. Cannabis use may delay transplant candidate listing or contribute to ineligibility. Cannabidiol (CBD) has recently exploded in popularity. Although generally well tolerated, safe without significant side effects, and effective for a variety

2020 Current opinion in nephrology and hypertension

18. Talking Pot with Youth: A Cannabis Communication Guide for Youth Allies

; and • Lead you through the spectrum for using cannabis and support you in having judgment-free conversations about cannabis with youth. What This Guide Will Not Do It does not replace professional screening for, or treatment of, cannabis use disorder. WHAT IS CANNABIS? Cannabis, more commonly called marijuana, pot or weed, is a greenish or brownish material consisting of the dried flowers and leaves of the cannabis plant, Cannabis sativa. Hashish or cannabis resin is the dried brown or black resinous (...) Talking Pot with Youth: A Cannabis Communication Guide for Youth Allies A Cannabis Communication Guide for Youth Allies Co-designed with input from youth and youth allies Acknowledgements This guide is stronger because of the expertise of the youth and youth allies who were involved in its creation. Authors: Katie Fleming, MA, and Anna McKiernan, MA This project was supported by the Canadian Institutes of Health Research and benefited from the advice of Health Canada. CCSA would like

2016 Canadian Centre on Substance Abuse

19. Cannabis Use During Pregnancy and Lactation: A Practice Resources for Health Care Providers

) was enacted, establishing a framework for the possession, distribution, sale and production of cannabis in Canada. (5) Cannabis is defined in the Act to include marijuana, hashish, hash oil or any other preparation of the cannabis plant. (5) In 2016, 16.9% of Canadian women between the ages of 15-44 reported past year use of cannabis which was an increase from the self reported 12.6% in 2015. (6) In British Columbia (BC), approximately 3.5% of pregnant women and individuals reported cannabis use (...) -on-Obstetric-Practice/Marijuana- Use-During-Pregnancy-and-Lactation?IsMobileSet=false n Midwives Association of British Columbia. Is it safe to use weed during pregnancy? https://www.bcmidwives.com/cgi/page.cgi/_zine.html/News_Announcements/Is_it_ safe_to_use_weed_during_pregnancy_ n Canadian Association of Midwives. Cannabis Use during Pregnancy. https:// canadianmidwives.org/2018/10/15/cannabis-use-during-pregnancy/ n Champlain Maternal Newborn Regional Program (CMNRP). Cannabis and Lactation Discussion

2020 British Columbia Perinatal Health Program

20. Counselling adolescents and parents about cannabis: A primer for health professionals

Counselling adolescents and parents about cannabis: A primer for health professionals While cannabis use among adolescents is frequent in Canada, youth do recognize the potential harms, and increasingly expect knowledgeable health care providers to discuss substance use in everyday practice. This practice point provides sound, evidence-based tools to help health professionals address non-medical (recreational) cannabis use and its related risks. After highlighting how to make the clinical (...) setting a safe space for youth to talk about psychoactive substances, specific strategies for approaching cannabis use in effective, developmentally appropriate ways are described. Consistent with current literature, screening questionnaires to help structure discussion and identify adolescents who may benefit from more specialized interventions are recommended. Because one in six adolescents who experiments with cannabis goes on to misuse it, appraising their willingness to change risky behaviours

2020 Canadian Paediatric Society

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>