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Mannheim Peritonitis Index

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41. Perforated peptic ulcer: clinical presentation, surgical outcomes, and the accuracy of the Boey scoring system in predicting postoperative morbidity and mortality. (PubMed)

in a university hospital. Clinical presentations and surgical outcomes were analyzed. Adjusted odds ratio (OR) of each Boey score on morbidity and mortality rate was compared with zero risk score. Receiver-operating characteristic curve analysis was used to compare the predictive ability between Boey score, American Society of Anesthesiologists (ASA) classification, and Mannheim Peritonitis Index (MPI).The study included 152 patients with average age of 52 years (range: 15-88 years), and 78% were male

2009 World Journal of Surgery

42. Evaluation of prognostic factors and scoring system in colonic perforation (PubMed)

(APACHE II), Mannheim peritonitis index (MPI) and peritonitis index of Altona (PIA II) scores were calculated preoperatively.Overall postoperative mortality rate was 23.1% (6 patients). Compared with survivors, non-survivors displayed low blood pressure, low serum protein and high serum creatinine preoperatively, and low blood pressure, low white blood cell count, low pH, low PaO2/FiO2, and high serum creatinine postoperatively. APACHE II score was significantly lower in survivors than in non

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2007 World journal of gastroenterology : WJG

43. Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer

to administration of chemotherapy and/or radiotherapy within the past 30 days Fever defined as an oral temperature greater than 38.5ºC once, or 38°C or greater on 2 or more occasions at least 1 hour apart during a 12-hour period, and suspected to be due to infection Expected low risk of serious medical complications as predicted by a Multinational Association for Supportive Care in Cancer risk-index score of greater than 20 No obvious signs of exit-site or tunnel intravascular catheter infection No known (...) no greater than 3 times upper limit of normal (ULN) Alkaline phosphatase no greater than 3 times ULN AST and ALT no greater than 5 times ULN No severe hepatic dysfunction Renal Creatinine no greater than 3.4 mg/dL Creatinine clearance at least 25 mL/min No renal failure requiring hemodialysis or peritoneal dialysis Cardiovascular No prior symptomatic arrhythmias No clinically relevant bradycardia No QTc interval prolongation No uncorrected hypokalemia No signs or symptoms of hypotension (systolic less

2003 Clinical Trials

44. A Study of Subcutaneous (sc) Mircera in Dialysis Patients With Chronic Renal Anemia.

patients >=18 years of age; chronic renal anemia; on dialysis (hemodialysis or peritoneal dialysis) therapy for at least 3 months; receiving sc epoetin alfa or beta for at least 3 months prior to the run-in period. Exclusion Criteria: women who are pregnant, breastfeeding or using unreliable birth control methods; use of any investigational drug within 30 days preceding the run-in phase, or during the run-in or study treatment period. Contacts and Locations Go to Information from the National Library (...) Cleveland, Ohio, United States, 44106 United States, Texas Houston, Texas, United States, 77030 United States, West Virginia Morgantown, West Virginia, United States, 26506 Germany Berlin, Germany, 10625 Mannheim, Germany, 68167 Villingen-schwenningen, Germany, 78054 Wiesloch, Germany, 69168 Italy Bari, Italy, 70124 Bergamo, Italy, 24128 Lecco, Italy, 23900 Lodi, Italy, 26900 Milano, Italy, 20122 Modena, Italy, 41100 Pavia, Italy, 27100 Vicenza, Italy, 36100 Spain Barcelona, Spain, 08036 Madrid, Spain

2006 Clinical Trials

45. Hartmann's reversal is associated with high postoperative adverse events. (PubMed)

of diverticular disease, severity of peri toneal contamination (Mannheim Peritonitis Index), and op erative urgency, patients who underwent Hartmann's rever sal were 2.1 times more likely to have adverse surgical events during their postoperative period (95 percent confidence interval for odds ratio = 1.3-3.3).Hartmann's reversal is a complex surgical procedure that is associated with a high prevalence of postoperative adverse events in comparison with primary resection and anastomosis. To minimize

2005 Diseases of the Colon & Rectum

46. Evaluation of the risk of a nonrestorative resection for the treatment of diverticular disease: the Cleveland Clinic diverticular disease propensity score. (PubMed)

= 2.32), Mannheim peritonitis index >10 (odd's ratio = 6.75), operative urgency (emergency, urgent vs. elective surgery, odd's ratio = 16.08 vs. 13.32), and Hinchey stage > II (odd's ratio = 27.82). The area under the receiver operating characteristic curve for the choice of operative procedure was 93.9 percent.Although Hartmann's resection was associated with a higher incidence of postoperative adverse events, the choice of operation was dependent on the patient presentation and intra-abdominal (...) and anastomosis and 12 percent, 43.9 percent, and 14.6 percent for Hartmann's resection, respectively (P < 0.001). There was no difference in the readmission rates between primary resection and anastomosis and Hartmann's resection (7.6 percent vs. 9.9 percent, P = 0.428). Laparoscopy was used for 32.7 percent of primary resection and anastomosis vs. 1.6 percent for Hartmann's resection (P < 0.001). Independent predictors in favor for Hartmann's resection were body mass index > or = 30 kg/m2 (odd's ratio

2006 Diseases of the Colon & Rectum

47. The effect of ranitidine on postoperative infectious complications following emergency colorectal surgery: a randomized, placebo-controlled, double-blind trial. (PubMed)

Peritonitis Index (MPI) was significantly higher in group I compared with group II (p < 0.05). Wound infection, intraabdominal abscess, septicemia, and pneumonia were 12.9%, 5.2%, 3.8% and 14%, respectively in group I. In group II, the infectious complications were 16.1%, 6.8%, 6.9% and 22%, respectively. Twelve patients (13.8%) in the placebo group developed more than one complication compared with 5 patients (6.5%) in the ranitidine group.Ranitidine may have a beneficial effect on postoperative (...) the hospital. Thirty patients were withdrawn from the study (for reasons such as other diagnosis, refused to continue, medication not given as prescribed).Patients were observed for signs of infectious complications; such as wound infection, intra-abdominal abscess, septicemia, and pneumonia.Both groups were similar with respect to age, sex, weight, duration of surgery, blood transfusions, and site of the procedure, as well as the histologic nature of the underlying disease process. However, the Mannheim

1998 Inflammation research : official journal of the European Histamine Research Society ... [et al.]

48. Significance of intraoperative peritoneal culture of fungus in perforated peptic ulcer. (PubMed)

with a PPU were studied. Clinical data and peritoneal fluid for culture were collected. Risk factors for a positive peritoneal fluid culture of fungus and outcome were evaluated, and related to the development of surgical site infection, duration of hospital stay and mortality rate.One hundred and forty-five patients with a PPU were included; 63 (43.4 per cent) had positive peritoneal fluid fungal culture. Age, preoperative organ failure, delay in operation, high Mannheim Peritonitis Index (MPI (...) Significance of intraoperative peritoneal culture of fungus in perforated peptic ulcer. The incidence of postoperative fungal infection is increasing and the gastrointestinal tract is the major source, but antifungal therapy in perforated peptic ulcer (PPU) is still controversial. The aim of this study was to determine the significance of intraoperative peritoneal fluid culture of fungus and establish the indications for treatment.Between July 1997 and September 2001, all patients admitted

2003 British Journal of Surgery

49. Laparoscopic two-stage left colonic resection for patients with peritonitis caused by acute diverticulitis. (PubMed)

acute diverticulitis. Secondarily, Hartmann's reversal (Stage 2) also was performed laparoscopically.Thirty-one patients were studied. The median Mannheim Peritonitis Index score was 21 (+/-5; range, 12-32). The conversion rate was 19 and 11 percent for Stage 1 and Stage 2, respectively. There was no perioperative uncontrolled sepsis. Overall operative 30-day mortality and morbidity rates were 3 and 23 percent for Stage 1, and 0 and 15 percent for Stage 2, respectively. Stoma reversal was possible (...) Laparoscopic two-stage left colonic resection for patients with peritonitis caused by acute diverticulitis. Purulent or fecal peritonitis is one of the most serious complications of acute diverticulitis. Up to one-fourth of patients hospitalized for acute diverticulitis require an emergent operation for a complication, including abscess, peritonitis, or stenosis. Open Hartmann's procedure has been the operation of choice for these patients. The advantages of laparoscopy could be combined

2007 Diseases of the Colon & Rectum

50. Multicentre, randomized clinical trial of primary versus secondary sigmoid resection in generalized peritonitis complicating sigmoid diverticulitis. (PubMed)

randomized to undergo primary or secondary resection. The main endpoint was occurrence of generalized or localized postoperative peritonitis. The Mannheim Peritonitis Index score was calculated for each patient to check for comparability of groups.Postoperative peritonitis occurred less often after primary than secondary resection whether considering the first procedure only (one of 55 patients versus ten of 48; P < 0.01) or all procedures (one of 55 versus 12 of 48; P < 0.001). Likewise, early (...) Multicentre, randomized clinical trial of primary versus secondary sigmoid resection in generalized peritonitis complicating sigmoid diverticulitis. The best way to manage generalized peritonitis complicating sigmoid diverticulitis is controversial. This randomized clinical trial involved a comparison of primary resection and suture, drainage with proximal colostomy followed by secondary resection.From January 1989 to December 1996, 105 patients of mean(s.d.) age 66(14) (range 32-91) years were

2000 British Journal of Surgery

51. Comparative study of left colonic Peritonitis Severity Score and Mannheim Peritonitis Index. (PubMed)

Comparative study of left colonic Peritonitis Severity Score and Mannheim Peritonitis Index. Prognostic evaluation of patients with left colonic perforation is useful in predicting mortality. The aims of this prospective study were to determine the prognostic value of the left colonic Peritonitis Severity Score (PSS) and to compare it with the Mannheim Peritonitis Index (MPI).One-hundred and fifty-six patients underwent emergency operation for distal colonic peritonitis. The PSS and MPI were (...) the MPI and PSS was 0.55 (P < 0.001). There was no difference between areas under the ROC curves for the two systems.The PSS and MPI are both well validated scoring systems for left colonic peritonitis. Their routine use might allow stratification of patients according to mortality risk.

2006 British Journal of Surgery

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