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Management of Severe Head Injury

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141. Programmatic management of latent tuberculosis infection in the European Union

and main findings from the mathematical modelling and cost- effectiveness analyses) is summarised in text and tables to provide an overview of the evidence that informed the possible options for programmatic management of LTBI. Complementary, topic-relevant evidence based guidelines are considered in the narrative text. In the tables with the evidence base, the following is presented: • Specific research questions used in the evidence collection process as headings/sub-headings; • Systematic reviews (...) of LTBI (Table 2), but evidence of increased risk of progression to active TB in people with LTBI belonging to clinical risk groups (i.e. PLHIV and severely immunocompromised persons) was found in all systematic reviews (Table 3). One evidence-based guideline for programmatic management of LTBI listed specific clinical risk groups (based on their risk of progression to active disease) for targeted screening and treatment, differentiated according the country’s socioeconomic and epidemiological profile

2019 European Centre for Disease Prevention and Control - Public Health Guidance

142. Preoperative or Postoperative Therapy for the Management of Patients with Stage II or III Rectal Cancer

Preoperative or Postoperative Therapy for the Management of Patients with Stage II or III Rectal Cancer Evidence-Based Series 2-4 Version 3 A Quality Initiative of the Program in Evidence-Based Care (PEBC), Cancer Care Ontario (CCO) Preoperative or Postoperative Therapy for the Management of Patients with Stage II or III Rectal Cancer Members of the Gastrointestinal Cancer Disease Site Group Evidence-based Series (EBS) 2-4 Version 3 was reviewed in 2019 and ENDORSED by the Gastrointestinal (...) Section 4: Document Review Summary and Review Tool March 13, 2019 For information about this document, the PEBC and/or the most current version of all reports, please visit the CCO web site at http://www.cancercare.on.ca/ or contact the PEBC office at: Phone: 905-527-4322 ext. 42822 Fax: 905-526-6775 Email: ccopgi@mcmaster.ca PEBC Report Citation (Vancouver Style): Wong R, Berry S, Spithoff K, Simunovic M, Chan K, Agboola O, et al. Preoperative or postoperative therapy for the management of patients

2019 Cancer Care Ontario

143. Guidelines on Supraventricular Tachycardia (for the management of patients with)

and electrophysiological procedures. The ESC published management Guidelines for supraventricular tachycardias (SVTs) in 2003 ; corresponding US guidelines have also been published, the most recent being in 2015. There is a need to provide expert recommendations for professionals participating in the care of patients presenting with SVT. In addition, several associated conditions where SVTs may coexist need to be explained in more detail. To address this topic, a Task Force was convened by the ESC, with the remit (...) by agreement of the expert panel after thorough deliberation. The document was peer-reviewed by official external reviewers. The strengths of the recommendations and levels of evidence of particular management options were weighed and graded according to predefined scales, as outlined above in Tables and , respectively. Overall, these Guidelines include evidence and expert opinions from several countries. The pharmacological and non-pharmacological antiarrhythmic approaches discussed may therefore include

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2019 European Society of Cardiology

144. Diagnosis and Management of Acute Pulmonary Embolism

Assessment of pulmonary embolism severity and the risk of early death 18 5.1 Clinical parameters of pulmonary embolism severity 18 5.2 Imaging of right ventricular size and function 18 5.2.1 Echocardiography 18 5.2.2 Computed tomographic pulmonary angiography 19 5.3 Laboratory biomarkers 19 5.3.1 Markers of myocardial injury 19 5.3.2 Markers of right ventricular dysfunction 19 5.3.3 Other laboratory biomarkers 19 5.4 Combined parameters and scores for assessment of pulmonary embolism severity 20 5.5 (...) for high-risk PE (Section 6.1). A dedicated management algorithm is proposed for high-risk PE ( Supplementary Figure ). NOACs are recommended as the first choice for anticoagulation treatment in a patient eligible for NOACs; VKAs are an alternative to NOACs. The risk-adjusted management algorithm ( Figure ) was revised to take into consideration clinical PE severity, aggravating conditions/comorbidity, and the presence of RV dysfunction. Chronic treatment after the first 3 months Risk factors for VTE

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2019 European Society of Cardiology

145. Management of Cancer Medication-Related Infusion Reactions

• For high-risk patients (e.g. patients who experienced severe anaphylaxis during the initial infusion, as well as patients with severe respiratory or cardiac disease and patients who are pregnant), a four-bag 16 step protocol can be used. 112,118,119,127 Management of Cancer Medication-Related Infusion Reactions 19 RECOMMENDATIONS FOR INFUSION REACTION PROPHYLAXIS [Return to Table 1.1] Risk Factors Given the potential for life-threatening injury when an IR occurs, it is important to consider all (...) whatsoever regarding the report content or use or application and disclaims any responsibility for its application or use in any way Management of Cancer Medication-Related Infusion Reactions 2 ACKNOWLEDGEMENTS Working Group Members Dr. Leta Forbes, Medical Oncologist, Provincial Head, Systemic Treatment Program, Cancer Care Ontario, Co-chair Andrea Crespo, Sr. Pharmacist, Systemic Treatment Program, Cancer Care Ontario, Co-chair Daniela Gallo-Hershberg, Pharmacist, Group Manager, Systemic Treatment

2019 Cancer Care Ontario

146. Transcatheter aortic valve implantation (TAVI) for severe symptomatic aortic stenosis

implantation compared to AVR. TAVI was also associated with a lower incidence of strokes, major bleeding, acute kidney injury and new or worsening atrial fibrillation. ? A recent economic evaluation utilising the CoreValve US trial data was adapted to the NHSScotland setting. The results indicate that TAVI may be a cost-effective treatment option for severe aortic stenosis (AS) patients at high surgical risk. However, cost- effectiveness is contingent upon the TAVI device costs being less than £19,500 (...) of these is the multicentre PARTNER trial that recruited patients at 23 sites in the US, two in Canada and one in Germany. Patients with severe calcific AS and New York Heart Association (NYHA) functional class =II were randomised in two separate cohorts: high-risk surgical patients were randomised to undergo TAVI with the SAPIEN™ valve or surgical AVR (cohort A) while those who were considered not to be suitable candidates for surgery were randomised to TAVI or conservative treatment in the form of medical management

2017 Evidence Notes from Healthcare Improvement Scotland

147. Changing attitudes to the management of severe head injuries. (PubMed)

Changing attitudes to the management of severe head injuries. 990863 1977 01 29 2018 11 13 0007-1447 2 6046 1976 Nov 20 British medical journal Br Med J Changing attitudes to the management of severe head injuries. 1234-9 Lewin W W eng Journal Article England Br Med J 0372673 0007-1447 8W8T17847W Urea AIM IM Attitude of Health Personnel Brain Concussion pathology Brain Edema etiology Brain Injuries drug therapy Craniocerebral Trauma complications therapy Hematoma complications Humans

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1976 British medical journal

148. Early management of the severe head injury. (PubMed)

Early management of the severe head injury. 4821614 1974 06 10 2018 11 13 0035-9157 67 1 1974 Jan Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Early management of the severe head injury. 8-9 Gordon D S DS Crockard H A HA eng Journal Article England Proc R Soc Med 7505890 0035-9157 IM Adult Airway Obstruction therapy Blood Transfusion Cerebral Hemorrhage therapy Coma complications Cough complications Craniocerebral Trauma therapy Cyanosis complications Hemostasis Humans

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1974 Proceedings of the Royal Society of Medicine

149. Radial Head Arthroplasty A Clinical and Radiological Comparison of Monopolar and Bipolar Radial Head Arthroplasty

Radial Head Arthroplasty A Clinical and Radiological Comparison of Monopolar and Bipolar Radial Head Arthroplasty Radial Head Arthroplasty A Clinical and Radiological Comparison of Monopolar and Bipolar Radial Head Arthroplasty - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Radial Head Arthroplasty A Clinical and Radiological Comparison of Monopolar and Bipolar Radial Head Arthroplasty (RHA) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03379935 Recruitment Status : Completed First Posted : December 20

2017 Clinical Trials

150. Should carbamazepine be administered to manage agitation and aggressive behaviour following paediatric acquired brain injury?

and behavioural disorders following traumatic brain injury: clinical evaluation and pharmacological management Brain Inj 2001;15:139–48. Azouvi P, Jokic C, Attal N, et al. Carbamazepine in agitation and aggressive behaviour following severe closed-head injury: results of an open trial. Brain Inj 1999;13:797–804. Roberts MA, Manshadi FF, Bushnell DL et al. Neurobehavioural dysfunction following mild traumatic brain injury in childhood: a case report with positive findings on positron emission tomography (PET (...) and obtundation with severe regression in all spheres of rehabilitation Comment(s) In 2008–2009, head injury accounted for over 34 000 admissions to UK hospitals of patients under the age of 15 years (DOH). Children often exhibit increased aggressive behaviour after acquired brain injury (ABI), particularly when there was a pre-morbid history of aggression, attention problems or anxiety (Cole). These aggressive behaviours may include anger outbursts, agitation, irritability and disinhibition

2011 BestBETS

151. Management of stable angina

myocardial perfusion is due to arterial narrowing resulting from underlying atherosclerotic CAD. Stable angina is usually assessed in the outpatient setting. It is important when taking a clinical history to identify, and manage appropriately, those patients whose symptoms may be due to the more severe changes of plaque erosion and rupture occurring as part of the spectrum of acute coronary syndrome (see SIGN guideline number 148 on acute coronary syndromes). 10 1.2.3 TARGET USERS OF THE GUIDELINE (...) is a symptom that suggests an individual has underlying obstructive CAD. Investigation to confirm the severity and extent of underlying CAD will allow management strategies to be developed and optimise cardiovascular risk reduction. 14 A significant proportion of patients with chest pain will not have angina and initial assessment should try to identify alternative diagnoses for these patients at an early stage. Patients with acute cardiac chest pain (suspected acute coronary syndrome) are outside

2018 SIGN

152. Managing GORD with PPIs in primary care

not be exclusively relied on to manage or diagnose a medical condition. NPS MedicineWise disclaims all liability (including for negligence) for any loss, damage or injury resulting from reliance on or use of this information. Read our . This website uses cookies. Read our . Footer © 2018 NPS MedicineWise. Providing independent, evidence-based information for the Australian Capital Territory (ACT), New South Wales, Northern Territory, Queensland, South Australia, Tasmania, Victoria and Western Australia. PO Box (...) Managing GORD with PPIs in primary care Managing GORD with PPIs in primary care | NPS MedicineWise 20 Years Of Helping Australians Make Better Decisions About Medicines, Medical Tests And Other Health Technologies. Log in Facebook Twitter LinkedIn Google Signing you in Use another account OR Login Form Email Password Log in to NPS MedicineWise Forgot password Forgot password Email Send reset instructions Set new password Reset Password Password Set password Account exists We found an existing

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2019 National Prescribing Service Limited (Australia)

153. Diagnosis and management of epilepsy in adults

after a seizure, and by recordings during sleep or following sleep deprivation. 16, 37, 38 Incidental epileptiform abnormalities are found in 0.5% of healthy young adults, but are more likely in people with learning disability and psychiatric disorders, patients with previous neurological insult (for example head injury, meningitis, stroke, cerebral palsy), and patients who have undergone neurosurgery. 39-41 Diagnosis and management of epilepsy in adults 3 • Diagnosis 2 +10 | In a patient in whom (...) for children the risks are higher after less than two years of seizure freedom than for more than two years. 153 Diagnosis and management of epilepsy in adults 4 • Treatment 2 + 2 - 2 + 1 + 1 ++20 | The effect of different rates of AED withdrawal on the risk of seizure recurrence has not been adequately studied. Important factors influencing a decision about AED withdrawal in adults include driving, employment, fear of further seizures, risks of injury or death with further seizures and concerns about

2018 SIGN

154. Pressure injury prevention in the operating theater

of pressure injuries: prevention and management guideline. Centre for Clinical Effectiveness, Monash Innovation and Quality, Monash Health, Melbourne, Australia. Pressure Injury: Operating Theater 17 Appendix 1 Question 1a search strategy Ovid Medline 1946 to Present with Daily Update 1 exp Pressure Ulcer/ 25 (pressure injur$ adj10 (tool$ or score$ or scale$ or scoring or instrument$ or equipment$ or device$)).mp. 2 exp Skin Ulcer/ 26 (pressure damag$ adj10 (tool$ or score$ or scale$ or scoring (...) Pressure injury prevention in the operating theater Pressure Injury: Operating Theater 1 Pressure injury prevention in the operating theater Citation Garrubba, M & Joseph, C. 2016. Pressure injury prevention in the operating theater: Rapid Review. Centre for Clinical Effectiveness, Monash Health, Melbourne, Australia. Executive Summary Background Pressure ulcers are ulcers on the skin caused by pressure or rubbing of the skin at points of weight bearing, or bony prominences of immobilised

2017 Monash Health Evidence Reviews

155. Policy Prevention of Sports-related Orofacial Injuries

protective equipment. 11-14 A large national survey confirmed the bicycle as the most common consumer sports product related to dental injuries in children, followed by playground equip- ment, other riding equipment (skates, inline skates), and trampolines. 3 The use of the trampoline provides specialized training for certain sports. However, when used recreationally, a signifi- cant number of head and neck injuries occurs, with head injuries most commonly a result of falls. 15 The American Academy (...) Data from this source found that in 2016-2017 school year, of the 699,441 injuries reported during competition, 223,623 (32 percent) occurred to the head/face; another 91,410 occurred during practice. 21 A similar study using this database followed athletes from 2008-2014 and found the rate of dental injuries in competition was three times higher than in practice. 21 For the majority of these reported injuries, the athlete was not wearing a mouthguard. 20 Review of this data-base found the highest

2018 American Academy of Pediatric Dentistry

156. Study Assessing Evaluation of the Interest of Serum S100B Protein Determination in the Management of Pediatric Mild Traumatic Brain Injury

Study Assessing Evaluation of the Interest of Serum S100B Protein Determination in the Management of Pediatric Mild Traumatic Brain Injury Study Assessing Evaluation of the Interest of Serum S100B Protein Determination in the Management of Pediatric Mild Traumatic Brain Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study (...) Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study Assessing Evaluation of the Interest of Serum S100B Protein Determination in the Management of Pediatric Mild Traumatic Brain Injury (PROS100B) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your

2016 Clinical Trials

157. Acute Kidney Injury Management

Acute Kidney Injury Management Acute Kidney Injury Management Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Acute Kidney Injury (...) Management Acute Kidney Injury Management Aka: Acute Kidney Injury Management , Acute Renal Failure Management From Related Chapters II. Management: General Consult Nephrology early in course Most patients with require hospitalization (except mild cases with known reversible cause) Eliminate s See Consider renal replacement therapy (see indications below) Consider specific therapy for underlying cause Example: s or Immunosuppressants in Nutritional Intake Maintain 30-50 KCal/Kg/day Hemodynamic stability

2018 FP Notebook

158. A Systematic Review of Randomized Controlled Trials Comparing Hypertonic Sodium Solutions and Mannitol for Traumatic Brain Injury: Implications for Emergency Department Management. (PubMed)

A Systematic Review of Randomized Controlled Trials Comparing Hypertonic Sodium Solutions and Mannitol for Traumatic Brain Injury: Implications for Emergency Department Management. To comparatively evaluate hypertonic sodium (HTS) and mannitol in patients following acute traumatic brain injury (TBI) on the outcomes of all-cause mortality, neurological disability, intracranial pressure (ICP) change from baseline, ICP treatment failure, and serious adverse events.PubMed, EMBASE, CENTRAL, Cochrane (...) Database of Systematic Reviews, ClinicalTrials.gov, and WHO ICTRP (World Health Organization International Clinical Trials Registry Platform) were searched (inception to November 2015) using hypertonic saline solutions, sodium chloride, mannitol, osmotic diuretic, traumatic brain injury, brain injuries, and head injury. Searches were limited to humans. Clinical practice guidelines and bibliographies were reviewed.Prospective, randomized trials comparing HTS and mannitol in adults (≥16 years

2016 The Annals of pharmacotherapy

159. The Many Organisational Factors Relevant to Planning Change in Emergency Care Departments: A Qualitative Study to Inform a Cluster Randomised Controlled Trial Aiming to Improve the Management of Patients with Mild Traumatic Brain Injuries. (PubMed)

can thrive (system antecedents for innovation). In addition, the position of the ED as the entry-point of the hospital points to the relevance of securing buy-in from other units.We identified several organisational factors relevant to realising change in ED management of patients who present with mild head injuries. These factors will inform the intervention design and process evaluation in a trial evaluating the effectiveness of our implementation intervention. (...) into account when implementing new clinical practices. This paper aims to provide an in depth analysis of the organisational context in which ED management of mild head injuries and implementation of new practices occurs, drawing upon organisational level theory.Semi-structured interviews were conducted with ED staff in Australia. The interviews explored the organisational context in relation to change and organisational factors influencing the management of patients presenting with mild head injuries. Two

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2016 PloS one

160. Head trauma and olfactory function (PubMed)

Head trauma and olfactory function Olfactory impairment is a well-established sequela of head injury. The presence and degree of olfactory dysfunction is dependent on severity of head trauma, duration of posttraumatic amnesia, injuries obtained, and as more recently established, age. Deficits in smell can be conductive or neurosensory, contingent on location of injury. The former may be amenable to medical or surgical treatment, whereas the majority of patients with neurosensory deficits (...) will not recover. Many patients will not seek treatment for such deficits until days, weeks, or even months after the traumatic event due to focus on more pressing injuries. Evaluation should start with a comprehensive history and physical exam. Determination of the site of injury can be aided by CT and MRI scanning. Verification of the presence of olfactory deficit, and assessment of its severity requires objective olfactory testing, which can be accomplished with a number of methods. The prognosis

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2018 World journal of otorhinolaryngology - head and neck surgery

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