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Management of Severe Head Injury

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10581. Non-pharmacological management of orthostatic hypotension after spinal cord injury: a critical review of the literature Full Text available with Trip Pro

Non-pharmacological management of orthostatic hypotension after spinal cord injury: a critical review of the literature Non-pharmacological management of orthostatic hypotension after spinal cord injury: a critical review of the literature Non-pharmacological management of orthostatic hypotension after spinal cord injury: a critical review of the literature Gillis D J, Wouda M, Hjeltnes N CRD summary The authors concluded that there was inconclusive evidence about compression and pressure (...) , upper body exercise and biofeedback for controlling orthostatic hypotension during rehabilitation in spinal cord injury; functional electrical stimulation of the legs showed the most promise. Limitations in the review methods and reporting of study quality undermined the reliability of the findings about functional electrical stimulation. Authors' objectives To evaluate the effects of non-pharmacological management of orthostatic hypotension during rehabilitation in people with spinal cord injury

2008 DARE.

10582. Management of adult victims of sexual assault

Medline 1980-September2000 , search on exp “rape” as subject heading, limited to “adult” limited “ english language” combined with exploded subject headings HIV infection,/sexually transmitted diseases, / patient care management. Cochrane library Issue 4 2000 , search -sexual and assault, Mesh exp “rape” 6 References 1. Rogers D. Physical Aspects of alleged sexual a ssaults Med Sci Law 1996 36:2; 117-122 2.Hillman R. O’Mara N. Tomlinson D. Harris JRW. Adult male victims of sexual assault (...) Management of adult victims of sexual assault 1 2001 National Guidelines on the Management of Adult Victims of Sexual Assault Clinical Effectiveness Group (Association for Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases • These recommendations are limited to the management of victims of sexual assault within a Genitourinary clinic setting and include screening for and treatment of sexually transmitted infections (STIs) and addressing the need for psychological

2001 British Association for Sexual Health and HIV

10583. Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate-to-Severe Plaque-Type Psoriasis (Core Study)

Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate-to-Severe Plaque-Type Psoriasis (Core Study) Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate-to-Severe Plaque-Type Psoriasis (Core Study) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) , with higher scores reflecting greater disease severity. Erythema, thickness, and scaling are scored on a scale of 0 (none) to 4 (very severe) on 4 anatomic regions of the body: head, trunk, upper limbs, and lower limbs. Degree of involvement on each of the 4 anatomic regions is scored on a scale of 0 (no involvement) to 6 (90% to 100% involvement). Secondary Outcome Measures : Core Study: Percentage of Participants Who Achieved a 75% Improvement (Response) in PASI Score at Week 24 [ Time Frame: Week 0

2008 Clinical Trials

10584. Extension Study to Evaluate the Safety of Q8003 in Patients With Acute Moderate to Severe Pain

Extension Study to Evaluate the Safety of Q8003 in Patients With Acute Moderate to Severe Pain Extension Study to Evaluate the Safety of Q8003 in Patients With Acute Moderate to Severe Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) . Condition or disease Intervention/treatment Phase Acute Moderate to Severe Pain Drug: Q8003 Drug: Placebo Phase 3 Detailed Description: The currently designated acute pain lead-in study is Study Q8003-007, which is a safety and efficacy study of Q8003 in the management of post-bunionectomy pain. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 16 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking

2007 Clinical Trials

10585. Volume Replacement With Albumin in Severe Sepsis

equal to 1, 3 or 4 renal score > 1 Exclusion Criteria: Age below 18 years Terminal state Known adverse reaction to albumin administration Severe sepsis or septic shock in patients after proved or suspected head injury, clinically active Congestive heart failure (NYHA score III and IV) Pathological conditions in which albumin administration is clinically indicated (hepatic cirrhosis with ascites, intestinal malabsorption syndrome, nephritic syndrome, burns) More than 24 hours since inclusion criteria (...) Volume Replacement With Albumin in Severe Sepsis Volume Replacement With Albumin in Severe Sepsis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Volume Replacement With Albumin in Severe Sepsis (ALBIOS

2008 Clinical Trials

10586. An Integrated Approach to Smoking Cessation in Severe Mental Illness (SMI)

, schizoaffective disorder or other severe mental disorder including bipolar disorder, major depression, or severe anxiety disorder). Age between 18 and 75 years. Current smokers who smoke at least 10 cigarettes per day. Must have been seen by a psychiatrist at least every 3 months for the last 6 months. Exclusion Criteria: Meet criteria for current alcohol/substance dependence (other than nicotine). Documented mental retardation, history of severe head injury with LOC, severe and untreated seizure disorder (...) An Integrated Approach to Smoking Cessation in Severe Mental Illness (SMI) An Integrated Approach to Smoking Cessation in Severe Mental Illness (SMI) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2008 Clinical Trials

10587. A Study of the Safety and Efficacy of Memantine in Moderate to Severe Alzheimer's Disease

A Study of the Safety and Efficacy of Memantine in Moderate to Severe Alzheimer's Disease A Study of the Safety and Efficacy of Memantine in Moderate to Severe Alzheimer's Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) disorder. Patients who, in the clinician's judgement, are likely to be placed in a nursing home within the next 6 months. Patients who had evidence of other neurological disorders that included, but were not limited to, stroke, Parkinson's disease, seizure disorder, or head injury with loss of consciousness within the prior 5 years Patients who had dementia that was complicated by other organic disease Patients who had dementia complicated by the presence of predominant delusions Contacts and Locations

2006 Clinical Trials

10588. A Randomized, Open-Label, Single-Dose, Small Study to Evaluate the Safety and Effectiveness of Hydromorphone in Patients With Short Term, Moderate to Severe Postoperative Pain

A Randomized, Open-Label, Single-Dose, Small Study to Evaluate the Safety and Effectiveness of Hydromorphone in Patients With Short Term, Moderate to Severe Postoperative Pain A Randomized, Open-Label, Single-Dose, Small Study to Evaluate the Safety and Effectiveness of Hydromorphone in Patients With Short Term, Moderate to Severe Postoperative Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information (...) , including but not limited to head injury, intracranial lesion, increased intracranial pressure, seizure disorder, stroke within the past 6 months, and disorders of cognition Patients with clinically significant impaired renal, hepatic, or hematological function adrenocortical insufficiency uncontrolled hypothyroidism or hyperthyroidism, or clinically significant urinary obstruction Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your

2006 Clinical Trials

10589. Intrathecal Baclofen Therapy and Paroxysmal Dysautonomia in Severe Brain-Injured Patients

of severe head injury, continuous intrathecal baclofen infusion will be delivered. The first week of study is double-blind: the first of two parallel groups receives CIBT and the second group receives placebo. The main outcome (number of neurovegetative episodes) is assessed at the end of first week. The second week of study is open labeled: active treatment is continued in the first group and the second group starts active CIBT treatment. The third week of study, treatment is stopped in both groups (...) Intrathecal Baclofen Therapy and Paroxysmal Dysautonomia in Severe Brain-Injured Patients Intrathecal Baclofen Therapy and Paroxysmal Dysautonomia in Severe Brain-Injured Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2005 Clinical Trials

10590. MR Scanning of Very Young Children With Severe Developmental Disorders

MR Scanning of Very Young Children With Severe Developmental Disorders MR Scanning of Very Young Children With Severe Developmental Disorders - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. MR Scanning (...) , a language disorder or mental retardation Exclusion Criteria: Significant motor or sensory impairment Major physical abnormalities History of serious head injury Identifiable neurologic disorder Metal implants Contraindication for MRI Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov

2005 Clinical Trials

10591. Prehospital endotracheal intubation in adult major trauma patients with head injury

with isolated severe head injruy 49.6% versus 22.8% OR 3 Davis DP et al, 2005 USA 13, 625 patients with moderate to severe traumatic brain injury included on a country trauma registry of whom 19.3% were intubated in the prehospital environment Observational Mortality Increased with prehospital intubation (OR 0.36 p Comment(s) Quite a few studies have been conducted to address the question of prehospital endotracheal intubation in major trauma victims needing airway management. All of them (...) November 2005 Last Modified: 8th May 2005 Status: Green (complete) Three Part Question In [patients with major trauma and head injury needing airway management in prehospital setting] is [endotracheal intubation better than bag and mask ventilation] for [improved outcomes] Clinical Scenario A 41 year old car driver was involved in a major road traffic accident, sustaining injuries to his head, a fracture of his right femur and multiple bruises on his chest. On scene he had altered sensorium and his GCS

2005 BestBETS

10592. BAES Guidelines on Training and Management of Endocrine Disease

are advised.Guidelines for the Surgical Management of Endocrine Disease 5 MULTINODULAR GOITRE * Biochemical toxicity must be controlled prior to surgery. * Unilateral surgery may be indicated when only one lobe is severely affected but, when there is significant involvement of both lobes, then total/near total thyroidectomy is recommended. * Recurrent laryngeal nerves must be clearly identified and safeguarded. The superior laryngeal nerve on each side should be safeguarded by careful ligation of the superior (...) with more radical surgery for malignant disease (viz hypoparathyroidism and recurrent laryngeal nerve injury). See Section 6.1. SURGICAL TREATMENT * The objective of surgery is to remove all macroscopic malignant disease in the thyroid, draining lymph nodes and involved adjacent structures.6 Guidelines for the Surgical Management of Endocrine Disease *A tumour of 1 cm diameter or less with no palpable lymphadenopathy or clinically overt disease in the contralateral lobe or evidence of distant metastases

2003 British Association of Endocrine and Thyroid Surgeons

10593. Effects of Head Elevation on Intracranial Pressure in Children

Details Study Description Go to Brief Summary: Head injury is the most common cause of mortality and acquired disability in childhood. It is common to elevate the head of patients at risk for increased intracranial pressure, although it is not clear if it is always beneficial. Every severe pediatric traumatic brain injured patient will have an optimal head position that prevents rising pressure in the brain. Condition or disease Intervention/treatment Phase Head Injury Procedure: Place HOB (...) in alternate positions from 0-50 degrees. Not Applicable Detailed Description: Head injury is the most common cause of mortality and acquired disability on childhood. Management of children at risk for intracranial hypertension is both complex and increasingly controversial. Also, effect of head position on intracranial pressure, cerebral perfusion pressure, adn cerebral venous outflow in the pediatric population has not been studied. We will examine the effect of head positioning on ICP, CPP, and cerebral

2008 Clinical Trials

10594. The Frequency Forward Head Posture in Subjects With Temporomandibular Disorder

The Frequency Forward Head Posture in Subjects With Temporomandibular Disorder The Frequency Forward Head Posture in Subjects With Temporomandibular Disorder - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) muscles and bones are lined up and work together in a harmonious form protecting the body of injury or gradual deformity and independently the attitude. The bad posture is a bad habit, but it can be which results in the disagreement of some parts of the body. These are at risk of injury or pain due to and increased tension that the disagreement imposes to the support structures. Several study confirm this occurrence relating that this the attitude can alter itself principally if a discomfort occurs

2008 Clinical Trials

10595. Radiation Therapy, Carboplatin, and Paclitaxel With or Without Amifostine in Treating Patients With Stage II, Stage III, or Stage IV Head and Neck Cancer

Radiation Therapy, Carboplatin, and Paclitaxel With or Without Amifostine in Treating Patients With Stage II, Stage III, or Stage IV Head and Neck Cancer Randomized Amifostine For SCCHN - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) Radiation: radiation Phase 2 Detailed Description: Amifostine is a drug that is used to treat moderate to severe xerostomia (dry mouth) for those who receive radiation therapy for head and neck cancer. It was approved by the FDA for use intravenously. This study plans to examine the effects of xerostomia when Amifostine is used subcutaneously (by injection). Amifostine has been seen to be effective when used to combat the effects of dry mouth, but also has some side effects which are listed later

2004 Clinical Trials

10596. Phase III Trial Of Docetaxel Versus Docetaxel Plus ZD1839 In Head And Neck Cancer

Phase III Trial Of Docetaxel Versus Docetaxel Plus ZD1839 In Head And Neck Cancer Phase III Trial Of Docetaxel Versus Docetaxel Plus ZD1839 In Head And Neck Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) , unstable angina, congestive heart failure, or serious arrhythmia requiring medication Hypercalcemia related to head and neck cancer Brain metastasis Current peripheral neuropathy >= grade 2 at time of randomization Patients have co-existing condition that would preclude full compliance with the study Known hypersensitivity to ZD1839 (Iressa, gefitinib) or any excipients of this product; prior history of severe hypersensitivity reaction to Docetaxel or other drugs formulated with polysorbate 80 HIV

2004 Clinical Trials

10597. BION Treatment of Dysphagia After Radical Head-Neck Surgery

BION Treatment of Dysphagia After Radical Head-Neck Surgery BION Treatment of Dysphagia After Radical Head-Neck Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. BION Treatment of Dysphagia After (...) permanently ruin the swallowing apparatus. Thus, the majority of patients who undergo CRT develop severe swallowing problems, called dysphagia, that typically becomes worse by about 3-4 weeks following the beginning of CRT. In anticipation of all of these problems, subjects have a tube placed in the stomach (gastrostomy tube) so that they can be fed through the tube in the immediate postoperative period when the incision is fragile and when dysphagia develops during CRT. Clearly the management

2008 Clinical Trials

10598. Physiotherapy Treatment for Patients Suffering From Head and Neck Cancer

Physiotherapy Treatment for Patients Suffering From Head and Neck Cancer Physiotherapy Treatment for Patients Suffering From Head and Neck Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) of these modalities. Radiotherapy treatment for head and neck cancer often causes severe late term side effects. Radiotherapy induced damage of the skin, lymphatic system, cartilage and bone often leads to symptoms such as trismus, lymphoedema, decreased range of motion of the mouth, neck and tongue, difficulty in using the mimic muscles, difficulty in swallowing and pain. The severity of late side effects due to radiotherapy treatment for head and neck cancer often leaves the patients with a poor quality of life

2008 Clinical Trials

10599. A Clinical Investigation of the Copelandâ„¢ Humeral Resurfacing Head

A Clinical Investigation of the Copelandâ„¢ Humeral Resurfacing Head A Clinical Investigation of the Copeland™ Humeral Resurfacing Head - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Clinical (...) Investigation of the Copeland™ Humeral Resurfacing Head The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00698750 Recruitment Status : Terminated (Sponsor terminated study early due to limited enrollment and follow-up.) First Posted : June 17, 2008 Last Update Posted : June 21, 2017 Sponsor: Biomet

2008 Clinical Trials

10600. Study of Eye Pressure as a Predictor of Intracranial Pressure in the Acutely Head-Injured Population

24, 2007 Sponsor: Ohio State University Information provided by: Ohio State University Study Details Study Description Go to Brief Summary: The purpose of this study is to determine if the pressure in the eye of a severely head-injured person correlates with the pressure in the person's skull. This is a prospective study of patients aged 18 and older who have experienced a traumatic closed head injury and are intubated either before or during the time they are in the Emergency Department (ED (...) ventilation pose a significant challenge to assess neurologically, as they are almost always sedated and often chemically paralyzed to facilitate airway management. Therefore, it is in this population of intubated trauma patients with suspected head injury that we will evaluate the use of tonometry to predict intracranial pressure from intraocular pressure. Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 37 participants Observational Model: Defined

2007 Clinical Trials

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