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Management of Severe Head Injury

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61. PATTERN OF REFERRALS OF HEAD INJURY TO THE UNIVERSITY COLLEGE HOSPITAL, IBADAN (PubMed)

PATTERN OF REFERRALS OF HEAD INJURY TO THE UNIVERSITY COLLEGE HOSPITAL, IBADAN Although there are now many neurosurgical units in Nigeria, cases of head injury (HI) continue to present in the University College Hospital, UCH, Ibadan, from hospitals all over the country.This report aims to highlight the contemporary patterns of referrals of cases of head injury for neurosurgery in Ibadan.The study emanated from an analysis of registry of cases of head injury managed in our practice covering a 7 (...) in other health facilities in four out of Nigeria's six geopolitical zones including other teaching hospitals with practicing neurosurgeons. The reasons for these inter-hospital, inter-state referrals included absence of neurosurgical expertise (67%) or lack of other logistics like neuroimaging, bed space and intensive care unit services. Head Injury was caused by road accidents in more than 85% of the cases. The patients referred inter-state had more severe injuries, more delayed attainment

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2017 Annals of Ibadan postgraduate medicine

62. Antioxidants in experimental ischemia-reperfusion injury of the testis: Where are we heading towards? (PubMed)

Antioxidants in experimental ischemia-reperfusion injury of the testis: Where are we heading towards? Testicular torsion (TT) is a medical emergency that primary affects newborns and young adolescents. It causes testicular injury due to the torsion of the spermatic cord and its components, initially in the venous blood flow and finally in the arterial blood flow. Prompt diagnosis and early surgical management are necessary in managing this urgent situation. The process of the pathophysiological (...) events in ischemia-reperfusion is multifactorial and deals with the perception of the oxidative stress responsible for the consequences of ischemia/reperfusion (I/R) stress following TT. Duration and severity of torsion also play a significant role in the oxidative stress. A detrimental result of the defense system of the testes takes place resulting finally in testicular atrophy and impaired function. Antioxidant factors have been experimentally studied in an effort to front this state. They have

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2017 World journal of methodology

63. PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST)

PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST) PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) Brain Injury Drug: Dalteparin Drug: Saline Phase 3 Detailed Description: Patients with severe brain injury are at risk for developing blood clots in their legs, which can travel to the lungs. This potentially serious complication is known as venous thromboembolism (VTE). Anticoagulants are commonly used to prevent VTE in hospital patients. However, in patients with major head injury, anticoagulant prevention is commonly delayed for the fear that it can potentially lead to further bleeding

2018 Clinical Trials

64. Intracranial Pressure Monitoring in Sever Traumatic Brain Injury Single Center Experience

Intracranial Pressure Monitoring in Sever Traumatic Brain Injury Single Center Experience Intracranial Pressure Monitoring in Sever Traumatic Brain Injury Single Center Experience - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Intracranial Pressure Monitoring in Sever Traumatic Brain Injury Single Center Experience The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03721003 Recruitment Status : Not yet recruiting First

2018 Clinical Trials

65. Early management of patients with a head injury

of computed tomography (CT) scanning resources have been taken into account in subsequent guidelines. In 1984 the Harrogate guidelines made suggestions on the early management of patients with a head injury, 14 followed in 1999 by the Galasko report from the Royal College of Surgeons. 15 SIGN published SIGN 46: Early management of patients with a head injury in August 2000. 3 Since publication of SIGN 46 there have been developments in several aspects of head injury management, including imaging, transfer (...) should be followed up after discharge. The guideline does not discuss the detailed management of more severe head injuries, either pre- or in-hospital, which are already incorporated into guidelines from the American College of Surgeons, 4 the American Association of Neurosurgeons/Brain Trauma Foundation, 18 the European Brain Injury Consortium, 19 the Association of Anaesthetists/British Neuroanaesthesia Society, 20 and the Society of British Neurological Surgeons. 21 1.2.2 TARGET USERS

2009 SIGN

66. Management of Traumatic Brain Injury

, et al. Further experience in the management of severe head injury. J Neurosurg 1981; 54:289-299. Alali, A.S., Fowler, R.A., Mainprize, T.G., et al. Intracranial pressure monitoring in severe traumatic brain injury: results from the American College of Surgeons Trauma Quality Improvement Program. J Neurotrauma 30, 1737- 1746, 2013. Chesnut RM, Temkin N, Carney N et al. A trial of intracranial pressure monitoring in traumatic brain injury. N Engl J Med 367:2471-81, 2012. Chesnut RM. Intracranial (...) van den Brink, W. A., H. van Santbrink, E. W. Steyerberg, C. J. Avezaat, J. A. Suazo, C. Hogesteeger, W. J. Jansen, L. M. Kloos, J. Vermeulen and A. I. Maas. Brain oxygen tension in severe head injury. Neurosurgery 46(4): 868- 876; discussion 876-868. 2000 Surgical Management Bullock RM, Chesnut R, Ghajar JBG, Gordon D, Hartl R,Newell DW, Servadei, F, Walters, BC, Wilberger JE. Guidelines for the Surgical Management of Traumatic Brain Injury. Neurosurgery, Supplement, Volume 58, Number 3. 2006

2015 American College of Surgeons

67. Head and neck imaging

Health. All Rights Reserved. 12 - MRI orbit, face, and neck (soft tissue) - CT paranasal sinuses and maxillofacial area - CT soft tissue neck Trauma Trauma Advanced imaging is considered medically necessary for traumatic injury to the head and neck region when the results of imaging are essential to establish a diagnosis and/or direct management. IMAGING STUDY - CT orbit, sella, or posterior fossa and outer, middle or inner ear - MRI orbit, face, and neck (soft tissue) - CT paranasal sinuses (...) is required. Congenital and Developmental Conditions Advanced imaging is considered medically necessary for diagnosis and management of congenital and developmental conditions in the head and neck region when the results of imaging will impact treatment. IMAGING STUDY - CT orbit, sella, or posterior fossa and outer, middle or inner ear - MRI orbit, face and neck (soft tissue) - CT paranasal sinuses and maxillofacial area - CT soft tissue neck Infection and Inflammatory Conditions Sinusitis/rhinosinusitis

2019 AIM Specialty Health

68. Effects of Early Musical Intervention on Prevalence and Severity of Paroxysmal Sympathetic Hyperactivity After Severe Traumatic Brain Injury

Effects of Early Musical Intervention on Prevalence and Severity of Paroxysmal Sympathetic Hyperactivity After Severe Traumatic Brain Injury Effects of Early Musical Intervention on Prevalence and Severity of Paroxysmal Sympathetic Hyperactivity After Severe Traumatic Brain Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effects of Early Musical Intervention on Prevalence and Severity of Paroxysmal Sympathetic Hyperactivity After Severe Traumatic Brain Injury (MUSIC-TCNV) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies

2016 Clinical Trials

69. Neurogenic pulmonary edema after severe head injury: a transpulmonary thermodilution study. (PubMed)

Neurogenic pulmonary edema after severe head injury: a transpulmonary thermodilution study. Neurogenic pulmonary edema (NPE) is a possible complication of severe central nervous system insult. Its physiopathology is still debated. We report a fatal case of a 55-year-old man who was admitted because of severe head injury. The diagnosis of NPE was considered according to clinical and radiologic findings. Transpulmonary thermodilution study showed decreased stroke volume index and cardiac function (...) index. Indexed extravascular lung water was increased as well as pulmonary vascular permeability index. The impairment of the left ventricular function was confirmed by the echocardiographic study. Our case suggests that NPE imply both cardiac dysfunction and lung injury. Thus, transpulmonary thermodilution can be helpful in managing fluid balance and the choice of vasopressors in patients with life-threatening NPE.

2015 American Journal of Emergency Medicine

70. Early Tracheostomy Versus Standard of Care in Patients With Severe Head Injury

Early Tracheostomy Versus Standard of Care in Patients With Severe Head Injury Early Tracheostomy Versus Standard of Care in Patients With Severe Head Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) Procedure: Tracheostomy Not Applicable Detailed Description: Introduction; Most patients with severe head injury cannot protect their airway, have excessive secretions and inadequate spontaneous breathing which contributes to cerebral hypoxia. Thus, in their initial management the airway is secured with either an endotracheal tube (ETT) or a tracheostomy. In Mulago Hospital some of these patients are intubated and then subjected to the wait and see strategy of delayed or no tracheostomy, very few

2015 Clinical Trials

71. Intracranial pressure monitoring in severe traumatic brain injuries: a closer look at level 1 trauma centers in the United States. (PubMed)

College of Surgeons Trauma Quality Improvement Program database was queried for all patients admitted to level I trauma centers with isolated blunt severe TBI (AIS>3, GCS<9) who met criteria for ICP monitoring. Patients who had severe extracranial injuries, craniectomy, or death in the first 24h were excluded. Comparison between groups with and without ICP monitoring was made, analyzing demographics, comorbidities, mechanism of injury, head Abbreviated Injury Scale (AIS), vital signs on admission (...) Intracranial pressure monitoring in severe traumatic brain injuries: a closer look at level 1 trauma centers in the United States. The Brain Trauma Foundation (BTF) recently updated recommendations for intracranial pressure (ICP) monitoring in severe traumatic brain injury (TBI). The effect of ICP monitoring on outcomes is controversial, and compliance with BTF guidelines is variable. The purpose of this study was to assess both compliance and outcomes at level I trauma centers.The American

2017 Injury

72. Perfusion Abnormalities are Frequently Detected by Early CT Perfusion and Predict Unfavourable Outcome Following Severe Traumatic Brain Injury. (PubMed)

Perfusion Abnormalities are Frequently Detected by Early CT Perfusion and Predict Unfavourable Outcome Following Severe Traumatic Brain Injury. In patients with severe traumatic brain injury (TBI), early CT perfusion (CTP) provides additional information beyond the non-contrast CT (NCCT) and may alter clinical management. We hypothesized that this information may prognosticate functional outcome.Five-year prospective observational study was performed in a level-1 trauma centre on consecutive (...) predicting model for unfavourable outcome.Fifty patients were investigated with CTP (one excluded for the absence of TBI) [male: 80%, median age: 35 (23-55), prehospital intubation: 7 (14.2%); median GCS: 5 (3-7); median injury severity score: 29 (20-36); median head and neck abbreviated injury scale: 4 (4-5); median days in ICU: 10 (5-15)]. Thirty (50.8%) patients had an unfavourable outcome. GCS was a moderate predictor of unfavourable outcome (AUC = 0.74), while CTP variables showed greater predictive

2017 World Journal of Surgery

73. Risk Factors and Common Preventive Measures for Ventilator Associated Pneumonia in Patients With Severe Traumatic Brain Injury

Risk Factors and Common Preventive Measures for Ventilator Associated Pneumonia in Patients With Severe Traumatic Brain Injury Risk Factors and Common Preventive Measures for Ventilator Associated Pneumonia in Patients With Severe Traumatic Brain Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. Risk Factors and Common Preventive Measures for Ventilator Associated Pneumonia in Patients With Severe Traumatic Brain Injury The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our

2017 Clinical Trials

74. Transcranial LED Therapy for Severe Acute Traumatic Brain Injury (PubMed)

Transcranial LED Therapy for Severe Acute Traumatic Brain Injury Transcranial LED Therapy for Severe Acute Traumatic Brain Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Transcranial LED Therapy (...) for Severe Acute Traumatic Brain Injury (LED-TBI) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03281759 Recruitment Status : Recruiting First Posted : September 13, 2017 Last Update Posted : September 13, 2017 See Sponsor

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2017 Clinical Trials

75. Effect of Antisecretory Factor, Given as a Food Supplement to Adult Patients With Severe Traumatic Brain Injury

Effect of Antisecretory Factor, Given as a Food Supplement to Adult Patients With Severe Traumatic Brain Injury Effect of Antisecretory Factor, Given as a Food Supplement to Adult Patients With Severe Traumatic Brain Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) this and thus reduce cerebral edema in traumatic brain injury. Furthermore, the reduction of cerebral edema is hypothesized to decrease intracranial pressure, reduce the development of secondary brain damage and subsequently reduce treatment intensity levels and death. Aims and Objectives Though, the number of patients with severe traumatic head injury in Sweden is decreasing and the need for a larger, randomized trial in a centre with large volumes of traumatic brain injury is needed The primary focus

2017 Clinical Trials

76. Intensive Faciltiation of Swallowing in Patients With Severe Dysphagia After Acquired Brain Injury

Intensive Faciltiation of Swallowing in Patients With Severe Dysphagia After Acquired Brain Injury Intensive Faciltiation of Swallowing in Patients With Severe Dysphagia After Acquired Brain Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Intensive Faciltiation of Swallowing in Patients With Severe Dysphagia After Acquired Brain Injury The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03145740 Recruitment Status : Completed First Posted : May 9, 2017 Last Update Posted : May 9, 2017 Sponsor

2017 Clinical Trials

77. Falling down a flight of stairs: The impact of age and intoxication on injury pattern and severity (PubMed)

Falling down a flight of stairs: The impact of age and intoxication on injury pattern and severity Falling down a flight of stairs is a common injury mechanism in major trauma patients, but little research has been undertaken into the impact of age and alcohol intoxication on the injury patterns of these patients. The aim of this study was to compare the impact of age and alcohol intoxication on injury pattern and severity in patients who fell down a flight of stairs.This was a retrospective (...) observational study of prospectively collected trauma registry data from a major trauma centre in the United Kingdom comparing older and younger adult patients admitted to the Emergency Department following a fall down a flight of stairs between July 2012 and March 2015.Older patients were more likely to suffer injuries to all body regions and sustained more severe injuries to the spine; they were also more likely to suffer polytrauma (23.6% versus 10.6%; p < 0.001). Intoxicated patients were more likely

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2017 Trauma (London, England)

78. Effect of Age on Glasgow Coma Scale in Patients with Moderate and Severe Traumatic Brain Injury: An Approach with Propensity Score-Matched Population (PubMed)

Effect of Age on Glasgow Coma Scale in Patients with Moderate and Severe Traumatic Brain Injury: An Approach with Propensity Score-Matched Population Background: The most widely used methods of describing traumatic brain injury (TBI) are the Glasgow Coma Scale (GCS) and the Abbreviated Injury Scale (AIS). Recent evidence suggests that presenting GCS in older patients may be higher than that in younger patients for an equivalent anatomical severity of TBI. This study aimed to assess (...) these observations with a propensity-score matching approach using the data from Trauma Registry System in a Level I trauma center. Methods: We included all adult patients (aged ≥20 years old) with moderate to severe TBI from 1 January 2009 to 31 December 2016. Patients were categorized into elderly (aged ≥65 years) and young adults (aged 20-64 years). The severity of TBI was defined by an AIS score in the head (AIS 3‒4 and 5 indicate moderate and severe TBI, respectively). We examined the differences in the GCS

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2017 International journal of environmental research and public health

79. S100 Biomarker in the Acute Management of Mild Head Injuries

. By enrolling a large consecutive sample of patients the investigators are validating this new guideline. Emergency department assessment data is combined with long-term outcome parameters and blood-based biomarkers of neurotrauma. The main aims of the study are: the validation of the Scandinavian guidelines for initial management of minimal, mild and moderate head injuries in adults the examination of novel blood-based biomarkers of acute brain injury that correlate with the radiological severity (...) S100 Biomarker in the Acute Management of Mild Head Injuries S100 Biomarker in the Acute Management of Mild Head Injuries - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. S100 Biomarker in the Acute

2015 Clinical Trials

80. Broad Validation Study of a Management Algorithm Mild Head Injury in Children

Title: Multicenter Prospective Broad Validation of a Management Algorithm Mild Head Injury in Children Actual Study Start Date : November 16, 2015 Actual Primary Completion Date : August 2018 Actual Study Completion Date : September 2018 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Outcome Measures Go to Primary Outcome Measures : Number of patients with clinically severe intracranial injury and classified at risk (top and middle) according (...) Broad Validation Study of a Management Algorithm Mild Head Injury in Children Broad Validation Study of a Management Algorithm Mild Head Injury in Children - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2015 Clinical Trials

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