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Malaria Chemoprophylaxis

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81. Chemoprophylaxis of malaria. (PubMed)

Chemoprophylaxis of malaria. 318895 1977 03 15 2018 11 13 0007-1447 1 6052 1977 Jan 01 British medical journal Br Med J Chemoprophylaxis of malaria. 49-50 Peters W W eng Letter England Br Med J 0372673 0007-1447 0 Antimalarials AIM IM Antimalarials therapeutic use Humans Malaria prevention & control Plasmodium vivax 1977 1 1 1977 1 1 0 1 1977 1 1 0 0 ppublish 318895 PMC1603647 Ann Trop Med Parasitol. 1975 Jun;69(2):141-5 1155986

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1977 British medical journal

82. Chemoprophylaxis of malaria. (PubMed)

Chemoprophylaxis of malaria. 837161 1977 04 30 2018 11 13 0007-1447 1 6058 1977 Feb 12 British medical journal Br Med J Chemoprophylaxis of malaria. 447 Bergson V V eng Letter England Br Med J 0372673 0007-1447 0 Antimalarials 0 Drug Combinations 88463U4SM5 Sulfadoxine Z3614QOX8W Pyrimethamine AIM IM Antimalarials administration & dosage therapeutic use Drug Combinations Humans Malaria prevention & control Pyrimethamine therapeutic use Sulfadoxine therapeutic use 1977 2 12 1977 2 12 0 1 1977 2

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1977 British medical journal

83. Falciparum malaria despite chemoprophylaxis. (PubMed)

Falciparum malaria despite chemoprophylaxis. 380749 1979 10 24 2013 11 21 0007-1447 1 6177 1979 Jun 09 British medical journal Br Med J Falciparum malaria despite chemoprophylaxis. 1565 Moody P P eng Letter England Br Med J 0372673 0007-1447 886U3H6UFF Chloroquine S61K3P7B2V Proguanil AIM IM Chloroquine adverse effects Female Fetal Diseases chemically induced Humans Malaria prevention & control Plasmodium falciparum Pregnancy Pregnancy Complications, Infectious prevention & control Proguanil

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1979 British medical journal

84. Falciparum malaria despite chemoprophylaxis. (PubMed)

Falciparum malaria despite chemoprophylaxis. 376057 1979 09 01 2013 11 21 0007-1447 1 6174 1979 May 19 British medical journal Br Med J Falciparum malaria despite chemoprophylaxis. 1351 Bentley S J SJ eng Letter England Br Med J 0372673 0007-1447 0 Drug Combinations 886U3H6UFF Chloroquine 8W5C518302 Dapsone Z3614QOX8W Pyrimethamine AIM IM Chloroquine therapeutic use Dapsone therapeutic use Drug Combinations Humans Malaria prevention & control Plasmodium falciparum Pyrimethamine therapeutic use

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1979 British medical journal

85. Chemotherapy and Chemoprophylaxis of Malaria (PubMed)

Chemotherapy and Chemoprophylaxis of Malaria 14904985 2004 02 15 2018 12 01 0007-1447 1 4758 1952 Mar 15 British medical journal Br Med J Chemotherapy and chemoprophylaxis of malaria; clinical trials in 500 cases and mass prophylaxis in a hyperendemic area. 568-74 CHAUDHURI R N RN CHAKRAVARTY N K NK RAI CHAUDHURI M N MN JANARDAN POTI S S eng Journal Article England Br Med J 0372673 0007-1447 OM Chemoprevention Humans Malaria therapy 5221:35569:224 MALARIA/therapy 1952 3 15 1952 3 15 0 1 1952 3

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1952 British medical journal

86. Malaria. Chemoprophylaxis and chemotherapy. (PubMed)

Malaria. Chemoprophylaxis and chemotherapy. 4927912 1971 05 26 2018 11 13 0007-1447 2 5753 1971 Apr 10 British medical journal Br Med J Malaria. Chemoprophylaxis and chemotherapy. 95-8 Peters W W eng Journal Article Review England Br Med J 0372673 0007-1447 0 Antimalarials 0 Pyrimidines 0 Sulfonamides 0 Triazines 220236ED28 Amodiaquine 886U3H6UFF Chloroquine 8W5C518302 Dapsone A7V27PHC7A Quinine MVR3634GX1 Primaquine S61K3P7B2V Proguanil Z3614QOX8W Pyrimethamine AIM IM Amodiaquine therapeutic (...) use Antimalarials therapeutic use Chloroquine therapeutic use Dapsone therapeutic use Drug Resistance, Microbial Drug Synergism Humans Malaria drug therapy prevention & control Plasmodium falciparum drug effects Primaquine therapeutic use Proguanil therapeutic use Pyrimethamine therapeutic use Pyrimidines therapeutic use Quinine therapeutic use Sulfonamides therapeutic use Triazines therapeutic use 59 1971 4 10 1971 4 10 0 1 1971 4 10 0 0 ppublish 4927912 PMC1795523 JAMA. 1967 Jan 16;199(3):173-7

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1971 British medical journal

87. Chemoprophylaxis for Malaria (PubMed)

Chemoprophylaxis for Malaria 18730679 2010 06 28 2010 06 28 0008-1264 116 2 1972 Feb California medicine Calif Med Chemoprophylaxis for malaria. 51-2 Chin J J eng Journal Article United States Calif Med 0410260 0008-1264 1972 2 1 0 0 1972 2 1 0 1 1972 2 1 0 0 ppublish 18730679 PMC1518218

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1972 California Medicine

88. Malaria after international travel: a GeoSentinel analysis, 2003-2016. (PubMed)

with severe malaria; 31 children had severe malaria. Twelve travellers died.Malaria remains a serious threat to international travellers. Efforts must focus on preventive strategies aimed on children and VFRs, and chemoprophylaxis access and preventive measure adherence should be emphasized. (...) Malaria after international travel: a GeoSentinel analysis, 2003-2016. More than 30,000 malaria cases are reported annually among international travellers. Despite improvements in malaria control, malaria continues to threaten travellers due to inaccurate perception of risk and sub-optimal pre-travel preparation.Records with a confirmed malaria diagnosis after travel from January 2003 to July 2016 were obtained from GeoSentinel, a global surveillance network of travel and tropical medicine

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2017 Malaria journal

89. Malaria-Associated Mortality in the Australian Defence Force during the Twentieth Century. (PubMed)

contingents still show falciparum malaria's lethality despite the availability of effective malaria chemoprophylaxis. (...) Malaria-Associated Mortality in the Australian Defence Force during the Twentieth Century. Malaria has been a military problem throughout history capable of causing epidemics that stop military operations. Individual mortality was examined from records of the three major wars of the 20th century that involved Australia in which 133 (1914-1919), 92 (1943-1945), and two (1965-1967) soldiers are known to have died with malaria. Those dying were predominately enlisted soldiers with a mean age of 29

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2017 American Journal of Tropical Medicine & Hygiene

90. Response to fever and utilization of standby emergency treatment (SBET) for malaria in travellers to Southeast Asia: a questionnaire-based cohort study. (PubMed)

Response to fever and utilization of standby emergency treatment (SBET) for malaria in travellers to Southeast Asia: a questionnaire-based cohort study. Guidelines in several European countries recommend standby emergency treatment (SBET) for travellers to regions with low or medium malaria transmission instead of continuous chemoprophylaxis: travellers are advised to seek medical assistance within 24 h in case of fever and to self-administer SBET only if they are not able to consult a doctor (...) within the time period specified. Data on healthcare-seeking behaviour of febrile travellers and utilization of SBET is however scarce as only two studies were performed in the mid-1990s. Since tourism is constantly increasing and malaria epidemiology has dramatically changed in the meantime more knowledge is urgently needed.Some 876 travellers to destinations in South and Southeast Asia with low or medium malaria transmission were recruited in the travel clinic of the University Medical Center

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2017 Malaria journal

91. Grammomys surdaster, the Natural Host for Plasmodium berghei Parasites, as a Model to Study Whole-Organism Vaccines against Malaria. (PubMed)

-organism vaccines to induce sterile immunity, and compared the thicket rat model to conventional mouse models. Using P. berghei ANKA radiation-attenuated sporozoites, and P. berghei ANKA and P. yoelii chemoprophylaxis vaccination approaches, we found that standard doses of vaccine sufficient to protect laboratory mice for a long duration against malaria challenge, are insufficient to protect thicket rats, which require higher doses of vaccine to achieve even short-term sterile immunity. Thicket rats (...) Grammomys surdaster, the Natural Host for Plasmodium berghei Parasites, as a Model to Study Whole-Organism Vaccines against Malaria. AbstractInbred mice are commonly used to test candidate malaria vaccines, but have been unreliable for predicting efficacy in humans. To establish a more rigorous animal model, we acquired African woodland thicket rats of the genus Grammomys, the natural hosts for Plasmodium berghei. Thicket rats were acquired and identified as Grammomys surdaster by skull

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2017 American Journal of Tropical Medicine & Hygiene

92. Epidemiological and clinical assessment of a shared territorial malaria guideline in the 10 years of its implementation (Barcelona, North Metropolitan Area, Catalonia, Spain, 2007-2016). (PubMed)

Epidemiological and clinical assessment of a shared territorial malaria guideline in the 10 years of its implementation (Barcelona, North Metropolitan Area, Catalonia, Spain, 2007-2016). Malaria remains a major source of morbi-mortality among travellers. In 2007, a consensual multicenter Primary Care-Hospital shared guideline on travel-prior chemoprophylaxis, diagnosis and clinical management of imported malaria was set up in the Barcelona North Metropolitan area. The aim of the study (...) (13.7%) as well as those with prescribed chemoprophylaxis (10%). Severe malaria was diagnosed in 34 (17.9%) patients and ICU admittance was required in 2.6% of them. Organ sequelae (two renal failures and one post-acute distress respiratory syndrome) were recorded in 3 patients at hospital discharge, although all three were recovered at 30 days. None of the patients died. Patients complying with severity criteria were significantly males (p = 0.04), came from Africa (p = 0.02), were mainly non

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2017 Malaria journal

93. A report of cerebral malaria treated with automated red blood cell exchange. (PubMed)

A report of cerebral malaria treated with automated red blood cell exchange. Adjunctive automated whole blood or red blood cell exchange (RBCEx) can rapidly decrease malarial hyperparasitemia. Several case reports and series suggest improvement in clinical symptomatology; however, recent Centers of Disease Control and Prevention (CDC) recommendations concluded that RBCEx has no efficacy as an adjunctive therapy. We present a case of mental status changes secondary to cerebral malaria treated (...) with automated RBCEx resulting in rapid and dramatic neurologic improvement.An 84-year-old Somali woman presented with a 3-day history of altered mental status, spiking fevers, chills, bilateral leg pain and weakness, and intermittent diarrhea. Her travel history included a recent trip to Kenya for 1 month without antimalarial chemoprophylaxis. During the hospital stay, her health declined, and she became obtunded. Physical examination revealed fever, tachypnea, hypertension, hypoxia, and no response

2017 Transfusion

94. The end of a dogma: the safety of doxycycline use in young children for malaria treatment. (PubMed)

The end of a dogma: the safety of doxycycline use in young children for malaria treatment. Anti-malarial drug resistance to chloroquine and sulfadoxine-pyrimethamine has spread from Southeast Asia to Africa. Furthermore, the recent emergence of resistance to artemisinin-based combination therapy (ACT) in Southeast Asia highlights the need to identify new anti-malarial drugs. Doxycycline is recommended for malaria chemoprophylaxis for travel in endemic areas, or in combination with the use (...) of quinine for malaria treatment when ACT is unavailable or when the treatment of severe malaria with artesunate fails. However, doxycycline is not used in young children under 8 years of age due to its contraindication due to the risk of yellow tooth discolouration and dental enamel hypoplasia. Doxycycline was developed after tetracycline and was labelled with the same side-effects as the earlier tetracyclines. However, recent studies report little or no effects of doxycycline on tooth staining

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2017 Malaria journal

95. No, sleeping with a chicken probably won’t save you from Zika or malaria

of defense against malaria. “Measures to prevent mosquito bites include sleeping under long-lasting insecticidal nets, and using protective clothing and insect repellents. Depending on the malaria risk in the area to be visited, international travellers may also need to take preventive medication (chemoprophylaxis) prior to, during, and upon return from their travel.” NPR’s story included a comment from an outside source who thought the study was “pretty cool.” But I didn’t see any hint of skepticism (...) No, sleeping with a chicken probably won’t save you from Zika or malaria No, sleeping with a chicken probably won't save you from Zika or malaria - HealthNewsReview.org Note to our followers: Our nearly 13-year run of daily publication of new content on HealthNewsReview.org came to a close at the end of 2018. Publisher Gary Schwitzer and other contributors may post new articles periodically. But all of the 6,000+ articles we have published contain lessons to help you improve your critical

2016 HealthNewsReview

96. Prolonged parasite clearance in a Chinese splenectomized patient with falciparum malaria imported from Nigeria (PubMed)

chemoprophylaxis against malaria in Nigeria when he worked there as a construction worker between 2009 and 2014. The patient had three episodes of malaria in Nigeria and had a splenectomy due to a traffic accident 8 years ago from the time he was admitted to hospital. The patient was orally administrated a total of 320 mg/2.56 g dihydroartemisinin-piperaquine for 2 days and intravenously administrated a total of 3 000 mg artesunate for 18 days. The axillary temperature of the patient ranged between 37.0 (...) Prolonged parasite clearance in a Chinese splenectomized patient with falciparum malaria imported from Nigeria The spleen plays a pivotal role in the rapid clearance of parasitized red blood cells in patients with falciparum malaria after artemisinin treatment. Prolonged parasite clearance can be found in patients who have had a splenectomy, or those with hemoglobin abnormalities and/or reduced immunity, which are all distinguishable from artemisinin resistance. This paper reports on a case

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2017 Infectious diseases of poverty

97. The need for preventive and curative services for malaria when the military is deployed in endemic overseas territories: a case study and lessons learned (PubMed)

also conducted.One hundred twenty male Air Force personnel were interviewed (out of a group of 122 officers and airmen). All participants were deployed in the CAR for 14 months and were aware of the existence of chemoprophylaxis against malaria. The majority of the subjects (92.5%, 111/120) also knew that prophylaxis should be started prior to departure. However, the regular use of chemoprophylaxis was reported by only 61.7% (74/120) of the sample. Overall, 30.8% of the participants (37/120) had 44 (...) symptomatic episodes of malaria during deployment, and one person succumbed to severe malaria. All cases were associated with noncompliance with chemoprophylaxis.Better coordination with overseas healthcare services and the establishment of directly observed chemoprophylaxis may help to avoid similar outbreaks in the future.

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2017 Military Medical Research

98. Malaria Surveillance — United States, 2014 (PubMed)

% reported that they initiated and adhered to a chemoprophylaxis drug regimen recommended by CDC for the regions to which they had traveled. Thirty-two cases were among pregnant women, none of whom had adhered to chemoprophylaxis. Among all reported cases, 17.0% were classified as severe illness, and five persons with malaria died. CDC received 137 P. falciparum-positive samples for the detection of antimalarial resistance markers (although some loci for chloroquine and mefloquine were untestable for up (...) cases and prevent infections. VFR travelers continue to be a difficult population to reach with effective malaria prevention strategies. Evidence-based prevention strategies that effectively target VFR travelers need to be developed and implemented to have a substantial impact on the number of imported malaria cases in the United States. Fewer U.S. resident patients reported taking chemoprophylaxis in 2014 (27.2%) compared with 2013 (28.6%), and adherence was poor among those who did take

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2017 MMWR Surveillance Summaries

99. Determinants of malaria prophylaxis among German travelers to Kenya, Senegal, and Thailand. (PubMed)

Determinants of malaria prophylaxis among German travelers to Kenya, Senegal, and Thailand. Malaria chemoprophylaxis is a mainstay of malaria prevention in travelers. Adequate pretravel advice forms the basis for efficient malaria prophylaxis. This study assessed the determinants for seeking pretravel advice and evaluated the quality of advice from each source and its influence on the patterns and outcome of malaria prophylaxis intake.In March and April 2004, a self-administered questionnaire (...) of pretravel consultation were associated with the source of information consulted. Seventy-five percent of travelers from Senegal and Kenya received DTG compliant advice compared to only 17% of travelers from areas with low malaria risk in Thailand. Travelers returning from Kenya and Senegal had used correct chemoprophylaxis in only 65 and 47% of trips, respectively. In multivariate analysis, the factors determining correct intake among Senegal and Kenya travelers were receiving pretravel advice (from

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2017 Journal of Travel Medicine

100. Remote sensing and malaria risk for military personnel in Africa. (PubMed)

Remote sensing and malaria risk for military personnel in Africa. Nonimmune travelers in malaria-endemic areas are exposed to transmission and may experience clinical malaria attacks during or after their travel despite using antivectorial devices or chemoprophylaxis. Environment plays an essential role in the epidemiology of this disease. Remote-sensed environmental information had not yet been tested as an indicator of malaria risk among nonimmune travelers.A total of 1,189 personnel from 10 (...) the missions.Age, the lack of compliance with the chemoprophylaxis, and staying in areas with an average Normalized Difference Vegetation Index higher than 0.35 were risk factors for clinical malaria.Remotely sensed environmental data can provide important planning information on the likely level of malaria risk among nonimmune travelers who could be briefly exposed to malaria transmission and could be used to standardize for the risk of malaria transmission when evaluating the efficacy of antimalaria

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2017 Journal of Travel Medicine

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