How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

559 results for

Malaria Chemoprophylaxis

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

41. Summary of recommendations for the prevention of malaria by the Committee to Advise on Tropical Medicine and Travel (CATMAT)

scales for the strength and quality of the evidence. Recommendations: Used together and correctly, personal protective measures (PPM) and chemoprophylaxis very effectively protect against malaria infection. PPM include protecting accommodation areas from mosquitoes, wearing appropriate clothing, using bed nets pre-treated with insecticide and applying topical insect repellant (containing 20%–30% DEET or 20% icaridin) to exposed skin. Selecting the most appropriate chemoprophylaxis involves assessment (...) of malaria were developed with associated rating scales for the strength and quality of the evidence. CATMAT has taken into consideration both the need for protection and the potential for adverse effects of chemoprophylaxis. The guidelines also emphasize the varying degrees of endemicity in different regions. The health care provider should be properly informed to be able to provide appropriate guidance for the individual traveller. Recommendations The evidence-based CATMAT recommendations for malaria

2014 CPG Infobase

42. Failure of malaria chemoprophylaxis with mefloquine in an oversize traveller to Mozambique. (PubMed)

Failure of malaria chemoprophylaxis with mefloquine in an oversize traveller to Mozambique. A case of failure of mefloquine prophylaxis in an oversize traveller, who correctly took the drug. This case seems to be attributed to mefloquine resistance, however it is suggested that mefloquine dosage should be modulated by body weight, as is already indicated by some authorities.

Full Text available with Trip Pro

2013 Malaria journal

43. Towards improved uptake of malaria chemoprophylaxis among West African travellers: identification of behavioural determinants. (PubMed)

Towards improved uptake of malaria chemoprophylaxis among West African travellers: identification of behavioural determinants. Malaria is a potentially lethal illness for which preventive measures are not optimally used among all travellers. Travellers visiting friends and relatives in their country of origin (VFRs) are known to use chemoprophylaxis less consistently compared to tourist travellers. In this study, factors explaining the low use of chemoprophylaxis were pursued to contribute (...) travelling to West Africa had not started chemoprophylaxis; therefore, there is room for improvement. Risk reduction strategies could aim at improving attendance to travel clinics and focus on young-, business and long term travellers and VFRs who have experienced malaria during consultation. Risk reduction strategies should focus on improving self-efficacy and conceptions of response efficacy, including social environment to aim at creating the positive social context needed.

Full Text available with Trip Pro

2013 Malaria journal

44. Adult Malaria Chemoprophylaxis Prescribing Patterns in the Military Health System from 2007-2011. (PubMed)

Adult Malaria Chemoprophylaxis Prescribing Patterns in the Military Health System from 2007-2011. The Military Health System (MHS), with 9.7 million beneficiaries, represents an enormous pool of potential travelers requiring malaria prevention measures. A systematic search of the MHS electronic pharmacy record was performed for prescriptions of atovaquone-proguanil (AP), chloroquine (CQ), doxycycline (DC), mefloquine (MQ), primaquine (PQ) to adult patients from 2007 through 2011. Over 1,000,000

Full Text available with Trip Pro

2013 American Journal of Tropical Medicine & Hygiene

45. Point-of-care tests for malaria

of appropriate chemoprophylaxis and insect protection measures (3). For the reasons outlined above, malaria is an important differential diagnosis in febrile patients who have travelled to malaria endemic regions. Current Practice and Advantages over Existing Technology: a) Primary care assessment of patients with suspected malaria Existing Technology: Patient is clinically reviewed by General Practitioner (GP) and if malaria is suspected, liaison takes place with Infectious Diseases Registrar/medical (...) Point-of-care tests for malaria NIHR Diagnostic Evidence Cooperative Oxford www.oxford.dec.nihr.ac.uk Diagnostic Evidence Co-operative Oxford Cooperative Oxford HR Diagnostics Evidence Cooperative Oxford Clinical Question: In the primary care setting, what is the accuracy and utility of malaria point-of-care (POC) tests in the detection of parasitaemia caused by Plasmodium species, compared to standard laboratory practice using Microscopy and/or Polymerase Chain Reaction (PCR)? Background

2015 NIHR DEC Oxford

46. Malaria prophylaxis

availability Changes in product availability No changes in product availability since 1 January 2018. Goals and outcome measures Goals and outcome measures Goals Goals To support primary healthcare professionals to: Carry out a thorough risk assessment of people intending to travel to areas endemic for malaria. Give appropriate advice on malaria preventive measures including awareness of mosquito bites, bite prevention, and chemoprophylaxis. Reinforce the importance of prompt diagnosis and treatment (...) of malaria. Prescribe suitable malaria chemoprophylaxis and standby emergency treatment where appropriate. Outcome measures Outcome measures No outcome measures were found during the review of this topic. Audit criteria Audit criteria No audit criteria were found during the review of this topic. QOF indicators QOF indicators No QOF indicators were found during the review of this topic. QIPP - Options for local implementation QIPP - Options for local implementation No QIPP indicators were found during

2018 NICE Clinical Knowledge Summaries

47. Barriers to malaria prevention in US-based travelers visiting friends and relatives abroad: A qualitative study of West African immigrant travelers. (PubMed)

of statements.Participants described the high cost of provider visits and chemoprophylaxis, challenges in advocating for themselves in healthcare settings and concerns about offending or inconveniencing hosts as barriers to malaria prevention. Cultural barriers to accessing pre-travel care included competing priorities when trip planning, such as purchasing gifts for family, travel logistics and safety concerns. When participants sought pre-travel care, most consulted their primary care provider. Participants expressed (...) Barriers to malaria prevention in US-based travelers visiting friends and relatives abroad: A qualitative study of West African immigrant travelers. Over half of malaria cases reported in the USA occur among people travelling to visit friends and relatives (VFRs), predominantly to West Africa. Few studies have queried VFR travellers directly on barriers to seeking pre-travel care. We aim to describe the knowledge, attitudes and practices of VFRs travelling to malaria-endemic countries from

2019 Journal of Travel Medicine

48. Tropical Travel Trouble 007 Mega Malaria Extravaganza

as new safety data is about to emerge). To eradicate P. ovale and P. vivax in pregnant or breast feeding women, consider weekly chemoprophylaxis with chloroquine until delivery and breastfeeding is complete, on the basis of G6PD status treat with primaquine to prevent a future relapse. Children < 5kg get dosed at 5kg for ACT. HIV patients , avoid artesunate + SP if on co-trimoxazole. Or artesunate + amodiaquine if they are also on efavirenz or zidovudine. HIV patient Severe Malaria: Intravenous (...) Tropical Travel Trouble 007 Mega Malaria Extravaganza Mega Malaria Extravaganza • LITFL • Tropical Traveler Clinical Cases Emergency medicine and critical care medical education blog Search LITFL ... | | | Mega Malaria Extravaganza , last update March 1, 2019 aka 007 When you think tropical medicine, malaria has to be near the top. It can be fairly complex and fortunately treatment has become a lot simpler. This post is designed to walk you through the basic principals with links to more

2018 Life in the Fast Lane Blog

49. How can interventions that target forest-goers be tailored to accelerate malaria elimination in the Greater Mekong Subregion? A systematic review of the qualitative literature. (PubMed)

How can interventions that target forest-goers be tailored to accelerate malaria elimination in the Greater Mekong Subregion? A systematic review of the qualitative literature. Despite decreases in incidence and related mortality, malaria remains a major public health challenge in the Greater Mekong Sub-region (GMS). The emergence of artemisinin resistance threatens these gains and has prompted efforts to accelerate elimination in the region. In the GMS, transmission now clusters in hotspots (...) along international borders and among high-risk populations, including forest-goers. To eliminate malaria in the region, interventions must target such hard-to-reach populations. This review provides a comprehensive overview of the qualitative research on behaviours and perceptions that influence uptake of and adherence to malaria interventions among forest-goers in the GMS.A systematic search strategy was used to identify relevant sources, including database (OVID SP, PubMed, ISI Web of Knowledge

Full Text available with Trip Pro

2019 Malaria journal

50. Imported cases of malaria in Spain: observational study using nationally reported statistics and surveillance data, 2002-2015. (PubMed)

Imported cases of malaria in Spain: observational study using nationally reported statistics and surveillance data, 2002-2015. Malaria was eliminated in Spain in 1964. Since then, more than 10,000 cases of malaria have been reported, mostly in travellers and migrants, making it the most frequently imported disease into this country. In order to improve knowledge on imported malaria cases characteristics, the two main malaria data sources were assessed: the national surveillance system (...) and the hospital discharge database (CMBD).Observational study using prospectively gathered surveillance data and CMBD records between 2002 and 2015. The average number of hospitalizations per year was calculated to assess temporal patterns. Socio-demographic, clinical and travel background information were analysed. Bivariate and multivariable statistical methods were employed to evaluate hospitalization risk, fatal outcome, continent of infection and chemoprophylaxis failure and their association

2019 Malaria journal

51. Examining community perceptions of malaria to inform elimination efforts in Southern Mozambique: a qualitative study. (PubMed)

to health facilities, and lack of transportation.Several constraints and opportunities will potentially influence malaria elimination in Magude. Malaria awareness, trust in health institutions, and the demand for chemoprophylaxis could facilitate new interventions, such as mass drug administration. A lack of awareness of asymptomatic carriers, inadequate understanding of residual transmission, and barriers to care seeking could jeopardize uptake. Hence, elimination campaigns require strong community (...) Examining community perceptions of malaria to inform elimination efforts in Southern Mozambique: a qualitative study. In a background of renewed calls for malaria eradication, several endemic countries in sub-Saharan Africa are contemplating malaria elimination nationally or sub-nationally. In Mozambique, a strategy to eliminate malaria in the south is underway in the context of low endemicity levels and cross-border initiatives to eliminate malaria in South Africa and Eswatini. In this context

2019 Malaria journal

52. Antibiotics in malaria therapy: which antibiotics except tetracyclines and macrolides may be used against malaria? (PubMed)

Antibiotics in malaria therapy: which antibiotics except tetracyclines and macrolides may be used against malaria? Malaria, a parasite vector-borne disease, is one of the most significant health threats in tropical regions, despite the availability of individual chemoprophylaxis. Malaria chemoprophylaxis and chemotherapy remain a major area of research, and new drug molecules are constantly being developed before drug-resistant parasites strains emerge. The use of anti-malarial drugs (...) is challenged by contra-indications, the level of resistance of Plasmodium falciparum in endemic areas, clinical tolerance and financial cost. New therapeutic approaches are currently needed to fight against this disease. Some antibiotics that have shown potential effects on malaria parasite have been recently studied in vitro or in vivo intensively. Two families, tetracyclines and macrolides and their derivatives have been particularly studied in recent years. However, other less well-known have been

Full Text available with Trip Pro

2016 Malaria journal

53. The risk of imported malaria in security forces personnel returning from overseas missions in the context of prevention of re-introduction of malaria to Sri Lanka. (PubMed)

falciparum and two cases of Plasmodium ovale.This study investigated the knowledge and practices regarding malaria chemoprophylaxis among all the Sri Lankan security forces personnel returning from peacekeeping missions in malaria endemic countries over a 7 month period. Adherence to other malaria prevention measures, occurrence of adverse events and incident cases of malaria were also recorded maintaining the anonymity of the respondents. Potential associations for non-compliance were studied.Interviews (...) were carried out with 559 security forces personnel returning home from foreign deployments in malaria-endemic regions (males: 550, 98.4 %). The majority (553, 98.9 %) was well aware of the need for chemoprophylaxis during the overseas stay and its regular use as prescribed. The overall adherence to chemoprophylaxis was good with 78.7 % (440/559) reporting regular, as prescribed, use. Having better educational qualifications, being female, being prescribed mefloquine, having fever during deployment

Full Text available with Trip Pro

2016 Malaria journal

54. Distribution of malaria vectors and incidence of vivax malaria at Korean army installations near the demilitarized zone, Republic of Korea. (PubMed)

Distribution of malaria vectors and incidence of vivax malaria at Korean army installations near the demilitarized zone, Republic of Korea. As a result of the reintroduction of malaria in the Republic of Korea (ROK) in 1993 and the threat to military and civilian populations, the Korea Military National Defense (MND) increased emphasis on vector control in 2012 at ROK Army (ROKA) installations located near the DMZ, while decreasing chemoprophylaxis, fearing potential drug resistance. Mosquito (...) surveillance demonstrated a need for continuous monitoring of disease patterns among ROKA soldiers and vector malaria infection rates to ensure positive outcomes.Anopheles spp. were collected from May-October at three ROKA installations in three locations near the DMZ. Each of the areas included one installation <2 km and two installations 11-12 km from the DMZ in Paju and Yeoncheon counties, Gyeonggi Province. Anopheles spp. were identified by polymerase chain reaction (PCR) techniques and then assayed

Full Text available with Trip Pro

2016 Malaria journal

55. Targeting populations at higher risk for malaria: a survey of national malaria elimination programmes in the Asia Pacific. (PubMed)

Targeting populations at higher risk for malaria: a survey of national malaria elimination programmes in the Asia Pacific. Significant progress has been made in reducing the malaria burden in the Asia Pacific region, which is aggressively pursuing a 2030 regional elimination goal. Moving from malaria control to elimination requires National Malaria Control Programmes (NMCPs) to target interventions at populations at higher risk, who are often not reached by health services, highly mobile (...) and difficult to test, treat, and track with routine measures, and if undiagnosed, can maintain parasite reservoirs and contribute to ongoing transmission.A qualitative, free-text questionnaire was developed and disseminated among 17 of the 18 partner countries of the Asia Pacific Malaria Elimination Network (APMEN).All 14 countries that responded to the survey identified key populations at higher risk of malaria in their respective countries. Thirteen countries engage in the dissemination of malaria

Full Text available with Trip Pro

2016 Malaria journal

56. Malaria Chemoprophylaxis

Malaria Chemoprophylaxis Malaria Chemoprophylaxis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Malaria Chemoprophylaxis Malaria (...) Chemoprophylaxis Aka: Malaria Chemoprophylaxis , Malaria Prophylaxis From Related Chapters II. Precautions Malaria Prophylaxis taken exactly as prescribed does not ensure complete protection may still occur at 1 week to 1 year after infection may also recur after completing treatment III. Protocol Always check CDC for resistance before prescribing CDC Travelers Health for regional recommendations Chemoprophylaxis is for prevention only Dosing below does not apply to treatment Chemoprophylaxis Schedule Agents

2015 FP Notebook

57. Prolonged protection provided by a single dose of atovaquone-proguanil for the chemoprophylaxis of Plasmodium falciparum malaria in a human challenge model. (PubMed)

Prolonged protection provided by a single dose of atovaquone-proguanil for the chemoprophylaxis of Plasmodium falciparum malaria in a human challenge model. We conducted a randomized, placebo-controlled, double-blind trial to establish the efficacy of atovaquone-proguanil to prevent malaria with the goal of simulating weekly dosing in a human Plasmodium falciparum challenge model.Thirty volunteers randomly received 1 of the following dose regimens: (1) 250 milligrams of atovaquone and 100 (...) success).Single-dose atovaquone-proguanil provides effective malaria chemoprophylaxis against P. falciparum challenge at dosing intervals supportive of weekly dosing. Postexposure prophylaxis 4 days after challenge was 100% effective.

Full Text available with Trip Pro

2012 Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Controlled trial quality: uncertain

58. Malaria

and subtropical areas of the world — malaria does not occur naturally in the UK. Malaria can be imported to the UK by people who have become infected during time spent in areas where malaria is endemic. Travellers (in particular children) visiting friends and relatives are more likely than tourists to become infected with malaria as they tend to visit remote places, stay longer and are less likely to take malaria chemoprophylaxis. UK surveillance data from 2015 showed that where history of chemoprophylaxis (...) is endemic (adjusted OR 4.6, 95% CI 3.1–9.9). A literature review looking at possible risk factors for malaria deaths in travellers found that the main risk factors were: Non-use or inappropriate use of chemoprophylaxis. Older age. Male sex. Delay in seeking care. Delay in diagnosis. Incorrect treatment. Infection with P. falciparum . Non-immunity — people born in countries where malaria is endemic may have some immunity to malaria infection from continual exposure to the parasite. Immunity rapidly

2017 NICE Clinical Knowledge Summaries

59. Epicentre/ Médecins Sans Frontières Scientific Day 2017: Research and Discussion from the Malaria Session

per day compared to 9.0/100,000 in rural Aweil, where access to appropriate healthcare is more difficult. One strategy to deliver malaria treatment, which MSF has early on implemented in multiple sites, is seasonal malaria chemoprophylaxis (SMC). SMC consists of This regimen works in regions with seasonal malaria, generally those where >60% of the annual rainfall occurs over a 3 month period. : 24.9 north of the equator (Sahel region) and 14.1 south of the equator (East and South Africa (...) Epicentre/ Médecins Sans Frontières Scientific Day 2017: Research and Discussion from the Malaria Session Epicentre/ Médecins Sans Frontières Scientific Day 2017: Research and Discussion from the Malaria Session | PLOS Blogs Network PLOS Blogs Staff Blogs Blogs by Topic Biology & Life Sciences Earth & Environmental Sciences Multi-disciplinary Sciences Medicine & Health Research Analysis & Scientific Policy Diverse perspectives on science and medicine Staff Blogs Blogs by Topic Biology & Life

2017 PLOS Blogs Network

60. Guidelines for the treatment of malaria. Third edition

not be registered or may be unavailable. However prevention of transmission or the emergence of resistance are not relevant outside malaria-endemic areas. If the patient has taken chemoprophylaxis, the same medicine should not be used for treatment. Treatment of P. vivax, P. ovale and P. malariae malaria in travellers should be the same as for patients in endemic areas (see section 6). There may be delays in obtaining artesunate, artemether or quinine for the management of severe malaria outside endemic areas (...) haemolytic reactions. 6 | Treatment of uncomplicated malaria caused by P. vivax, P. ovale, P. malariae or P. knowlesi 696.5.3 | PREVENTION OF RELAPSE IN PREGNANT OR LACTATING WOMEN AND INFANTS Preventing relapse in pregnant or lactating women In women who are pregnant or breastfeeding, consider weekly chemoprophylaxis with chloroquine until delivery and breastfeeding are completed, then, on the basis of G6PD status, treat with primaquine to prevent future relapse. Conditional recommendation, moderate

2015 World Health Organisation Guidelines

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>