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Malar Rash

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1. A malar rash from inner Rio de Janeiro State, Brazil Full Text available with Trip Pro

A malar rash from inner Rio de Janeiro State, Brazil A 49-year-old previously healthy woman from Rio de Janeiro State, Brazil, presented with a right malar rash that started as a tiny pustule and progressed to an ulcerated papulonodular lesion within ten weeks. A presumptive diagnosis of zoonotic sporotrichosis was made based on excellent response to treatment and epidemiological linkage with a diseased cat.

2018 IDCases

2. Malar Rash

Malar Rash Malar Rash Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Malar Rash Malar Rash Aka: Malar Rash II. Pathophysiology Immune (...) -mediated erythematous rash III. Signs Sun sensitive, erythematous rash Butterfly-shape appearance Involves both cheeks and variably the bridge of nose IV. Causes (SLE) infection (or slapped cheek) Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Malar Rash." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Butterfly rash (C0277942) Concepts Finding

2018 FP Notebook

3. Spotting Zika spots: descriptive features of the rash used in 66 published cases. (Abstract)

%), lower limbs (5%) and both (3%). Mean rash duration was 6 days (range 3-11 days). The ZV exanthema is most frequently maculopapular, pruritic, sometimes with centrifugal spread from the trunk to extremities. This may include lower limb petechial purpura, palmoplantar lesions, oedema of limb extremities, and gingival bleeding or painful oral bullae. As ZV becomes more prevalent, recognition of the clinical features will enable earlier diagnosis and appropriate testing.© 2018 British Association (...) Spotting Zika spots: descriptive features of the rash used in 66 published cases. Zika virus (ZV) is an important emerging infection. Rash is a key feature, but the summative literature lacks description of the rash beyond 'maculopapular'. Our aim was to identify the cutaneous features described in the published literature. A literature search using defined terms for ZV cases reports and series was performed on the OVID, Clinical Key and University of Dundee's e-library journals databases

2018 Clinical & Experimental Dermatology

4. A strange lupus-like malar rash with renal involvement: an angioimmunoblastic T-cell lymphoma – A case report Full Text available with Trip Pro

A strange lupus-like malar rash with renal involvement: an angioimmunoblastic T-cell lymphoma – A case report Cutaneous malar rash and kidney involvement has not previously been reported as presenting symptoms of an angioimmunoblastic T-cell lymphoma (AITL). We report a case of a woman with erythematous rash. A PET-CT revealed a lymphadenopathy and splenomegaly. An inguinal lymph node biopsy showed an AITL. There was clinical improvement after prednisone.

2014 Clinical Case Reports

5. Malar Rash

Malar Rash Malar Rash Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Malar Rash Malar Rash Aka: Malar Rash II. Pathophysiology Immune (...) -mediated erythematous rash III. Signs Sun sensitive, erythematous rash Butterfly-shape appearance Involves both cheeks and variably the bridge of nose IV. Causes (SLE) infection (or slapped cheek) Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Malar Rash." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Butterfly rash (C0277942) Concepts Finding

2015 FP Notebook

6. Systemic lupus erythematosus

the skin and joints, although serositis, nephritis, haematological cytopenias, and neurological manifestations may occur during the course of the disease. Earlier diagnosis and better management have resulted in a lower prevalence of life-threatening disease. History and exam malar (butterfly) rash photosensitive rash discoid rash fatigue weight loss fever oral ulcers alopecia arthralgia/arthritis fibromyalgia Raynaud's phenomenon chest pain and shortness of breath hypertension signs of nephrosis (e.g

2018 BMJ Best Practice

8. CRACKCast E174 – Genitourinary and Renal Tract Disorders

be reduced by the disease. Usually broken down by two age groups: < 5 yrs – likely primary nephrotic syndrome – due to minimal change disease > 5 yrs – usually due to a secondary/systemic disease PSGN Lupus Here’s that list of causes: Primary proteinurea due to minimal change disease primary nephrotic syndrome (no gross hematuria or elevated creatinine level, normal complement levels, and no evidence of extrarenal causes such as a malar rash) Secondary causes: IgA nephropathy PSGN HUS HSP Lupus (...) a strep infection (can be provoked by any virus) classic HSP rash is usually diagnostic. Watch for renal or abdominal complications. These folks can become sick fast! ● Aggressive supportive care ○ Correct electrolytes ○ Treat pancreatic failure ○ Treat seizures ○ Treat hypertension ● No role for antibiotics (enhance release of verotoxin) Except: Pneumococcal-associated HUS often presents with pneumonia and should be treated ● Early consideration of dialysis ● PRBCs if Hgb < 60 ● ?consideration

2018 CandiEM

10. Guideline for the management of adults with Systemic Lupus Erythematosus Full Text available with Trip Pro

case series [ , ]; 2 SRs [ , ] NSAIDs Symptom control in mild non-renal lupus only 1 3 D 1 SR covers case series/reports [ ] Sunscreen (high-SPF UV-A and UV-B) Prevents UV-induced rashes and other manifestations 7 2 ++ B 1 blind RCT [ ]; 5 cohort studies [ ]; 1 case series [ ] Low-dose oral prednisolone (≤7.5 mg) Mild lupus and to prevent flares 0 4 D Expert opinion Higher doses of oral prednisolone ≤0.5 mg/kg/day Moderate lupus and prevention of flares 0 2 4 2+ D C To prevent flare: 1 blind RCT (...) [ ] Tacrolimus 1–3 mg/day (assess drug levels) Moderate/severe lupus, steroid-sparing 3 3 D 2 cohort studies [ , ]; 1 SR [ ] LEF (20 mg/day) Moderate lupus without subacute rash 3 3 D 1 small blind RCT [ ]; 1 cohort study [ ]; 1 SR [ ] CYC (see text for dosing) Severe lupus, including NPSLE, prevent flare, steroid-sparing 30 2 ++ B 4 open-label RCTs [ ]; 25 cohort studies covered by 1 SR [ ] Rituximab 1000 mg × 2 Refractory severe and moderate lupus; steroid-sparing 33 2+ C 1 blind RCT [ , ]; 3 open-label

2017 British Society for Rheumatology

11. CRACKCast E118 – SLE and Vasculitides

levels · Direct coombs test positive Table 108.1 is very busy – Remember the only mnemonic from med school SOAP BRAIN MD Serositis Oral Ulcers Arthritis Photosensitivity & Pulmonary Fibrosis Blood cells (pancytopenia) Renal, Raynauds ANA Immunologic (anti-Sm, anti-dsDNA) Neuropsych Malar Rash Discoid Rash [3] List drugs that induce lupus See Box 108.2 from Rosens 8 th Edition – SLE and Vasculitides Drugs Definitively Implicated in Causing Drug-Induced Lupus Procainamide Hydralazine Methyldopa (...) Wise Cracks [1] What is the differential for SLE patient and Chest pain? See Table 108.2 Rosens 9 th Edition – SLE and Vasculitides Pleuritis Pulmonary embolism Pneumonia Pericarditis Coronary artery disease [2] Name and identify 2 pathognomonic clinical features for lupus Malar Rash & Discoid Lupus [3] When should rheumatology be involved in the ED with a SLE patient? Hold up – your SLE patient is not just an automatic turf to CTU! Here is an important list to consider from box 108.3 in Rosens 8

2017 CandiEM

12. A rare case of suicidal ideation related to Adalimumab use Full Text available with Trip Pro

) and no known prior history of systemic lupus erythematosus or depression presented with suicidal ideations, joint pains and a malar rash after a recent change in her Adalimumab dose. She was treated for an acute ATIL episode based on her symptoms and serologies which were positive for anti-double-stranded deoxyribonucleic acid antibody. An inpatient psychiatric consultation determined that the patient's suicidal ideations may be an associated symptom of her current ATIL episode or possibly secondary to her

2018 Open access rheumatology : research and reviews

13. Rosacea - acne

striae. Systemic lupus erythematosus (SLE) — discoid or malar 'butterfly' distribution of a facial rash, often associated with photosensitivity and oral ulcers. Other complications include renal, neurological, haematological, or immunological disorders. Erysipelas — a bacterial infection usually caused by Group A beta haemolytic streptococci, predominantly affecting the lower limbs. When it involves the face it can have a ‘butterfly’ distribution on the cheeks and bridge of the nose (...) information, see the CKS topic on . Seborrhoeic dermatitis — yellow greasy scales on an erythematous base, usually found on the sebum-rich areas of the scalp and face (including the ears, eyebrows, and nasolabial folds). It varies in presentation from dandruff to erythroderma. For more information, see the CKS topic on . Contact dermatitis — eczematous rash with vesicles and scaling. A causative irritant or allergen can sometimes be identified and it may affect a person of any age. For more information

2018 NICE Clinical Knowledge Summaries

15. Management of Dengue Infection in Adults

pathophysiological changes during each phase of the disease will produce a rational approach in the management of dengue infection. 3.2 CLINICAL COURSE OF DENGUE INFECTION After the incubation period, the illness begins abruptly and will be followed by three phases: febrile, critical and recovery phase (refer to Figure 5). 2,3 i. Febrile Phase Patients develop high grade fever suddenly and usually last 2-7 days. It is often accompanied by facial flushing, rash, generalised body ache, vomiting and headache. 2,3 (...) than the level of alanine aminotransaminase (ALT)], hypoproteinaemia and hypoalbuminaemia are usually observed. 2-4 iii. Recovery/Reabsorption Phase After 24-48 hours of critical phase, usually plasma leakage stops followed by reabsorption of extravascular fluid. Patient’s general well being improves, appetite returns, gastrointestinal symptoms improve, haemodynamic status stabilises and diuresis ensues. Some patient may have a classical rash of “isles of white in the sea of red” with generalised

2015 Ministry of Health, Malaysia

16. Guidelines for the treatment of malaria. Third edition

2014; 6:CD008152. doi: 10.1002/14651858.CD008152.pub3. White NJ, Qiao LG, Qi G, Luzzatto L. Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common. Malar J 2012;11:418. 4 | Treatment of uncomplicated Plasmodium falciparum malaria 42 Guidelines for the treatment of malaria 3 RD EDITIONThe population benefits of reducing malaria transmission with gametocytocidal drugs such as primaquine require that a very high

2015 World Health Organisation Guidelines

17. Whom should you test for secondary causes of hypertension?

, malar rash); or laboratory analysis (elevated serum creatinine, low thyroid-stimulating hormone) (SOR: C, consensus-based guidelines). Patients with undifferentiated resistant hypertension should receive further directed evaluation for secondary causes (SOR: C, consensus-based guidelines). URI Citation Journal of Family Practice, 63(1) 2014: 41-42, 54. Rights OpenAccess. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. Collections hosted by hosted by

2014 Clinical Inquiries

18. Seborrheic area involvement in patients with systemic lupus erythematosus. (Abstract)

Seborrheic area involvement in patients with systemic lupus erythematosus. The most characteristic skin manifestation of systemic lupus erythematosus (LE) is malar rash characterized by an erythematous congestive sometimes secondarily squamous eruption over the cheeks and nasal bridge, that typically spares nasolabial folds. This rash is referred to as "acute cutaneous lupus erythematosus" (ACLE) (1). Recently, 2 SLE patients with remarkable skin involvement of seborrheic area (SA) came to our

2019 Journal of the European Academy of Dermatology and Venereology

19. Teriflunomide

mg; N=1, 14 mg). Common Adverse Events The following chart displays the most common adverse events seen in Pool 1, for which the incidence is greater on drug than placebo: Event Placebo Ter 7 Ter 14 N=421 N=429 N=415 % % % Diarrhea 8 14 17 Alopecia 4 11 15 Nausea 7 9 14 ALT increased 7 13 14 Influenza 9 10 12 Paraesthesia 8 10 11 Rash 4 5 6 Laboratory findings Reference ID: 3185084 18 The following chart displays the mean changes in important laboratory analytes in Pool 1: Mean change from (...) : 3185084 23 Hypersensitivity There were no life-threatening events that could reasonably be considered related to hypersensitivity. However, the following adverse reactions were reported more frequently on drug than on placebo in Pool 1: Event Placebo Ter 7 Ter 14 Rash 4% 5% 6% Pruritis 2% 4% 3% Erythema 0.5% 2% 1% Urticaria 0.5% 1% 1% Two cases of erythema nodosum and one case of erythema multiforme were reported in patients on teriflunomide (both doses) but these resolved with continued treatment

2012 FDA - Drug Approval Package

20. Immunological and Clinical Characteristics of Systemic Lupus Erythematosus: A Series from Morocco Full Text available with Trip Pro

antibodies (ANA) and anti-DNA antibodies by indirect immunofluorescence, followed by identification of anti-extractable nuclear antigen antibodies by ELISA. The female to male ratio was 6.1:1. Mean age was 31.72 years. The main clinical manifestations were arthritis (82%), mucocutaneous manifestations (80%), renal manifestations (50%), and hematological features (46%). Of the mucocutaneous features, the highest frequencies were observed in the malar rash (68%) and photosensitivity (60

2018 BioMed research international

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