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Malar Rash

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1. A malar rash from inner Rio de Janeiro State, Brazil (PubMed)

A malar rash from inner Rio de Janeiro State, Brazil A 49-year-old previously healthy woman from Rio de Janeiro State, Brazil, presented with a right malar rash that started as a tiny pustule and progressed to an ulcerated papulonodular lesion within ten weeks. A presumptive diagnosis of zoonotic sporotrichosis was made based on excellent response to treatment and epidemiological linkage with a diseased cat.

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2018 IDCases

2. Malar Rash

Malar Rash Malar Rash Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Malar Rash Malar Rash Aka: Malar Rash II. Pathophysiology Immune (...) -mediated erythematous rash III. Signs Sun sensitive, erythematous rash Butterfly-shape appearance Involves both cheeks and variably the bridge of nose IV. Causes (SLE) infection (or slapped cheek) Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Malar Rash." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Butterfly rash (C0277942) Concepts Finding

2018 FP Notebook

3. A strange lupus-like malar rash with renal involvement: an angioimmunoblastic T-cell lymphoma – A case report (PubMed)

A strange lupus-like malar rash with renal involvement: an angioimmunoblastic T-cell lymphoma – A case report Cutaneous malar rash and kidney involvement has not previously been reported as presenting symptoms of an angioimmunoblastic T-cell lymphoma (AITL). We report a case of a woman with erythematous rash. A PET-CT revealed a lymphadenopathy and splenomegaly. An inguinal lymph node biopsy showed an AITL. There was clinical improvement after prednisone.

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2014 Clinical Case Reports

4. Spotting Zika spots: descriptive features of the rash used in 66 published cases. (PubMed)

Spotting Zika spots: descriptive features of the rash used in 66 published cases. Zika virus (ZV) is an important emerging infection. Rash is a key feature, but the summative literature lacks description of the rash beyond 'maculopapular'. Our aim was to identify the cutaneous features described in the published literature. A literature search using defined terms for ZV cases reports and series was performed on the OVID, Clinical Key and University of Dundee's e-library journals databases (...) in December 2016; a later case report was included while the paper was under review. Diagnosis in all cases was via PCR. Exclusion criteria were Zika cases without rash or omitting any description of the rash. Ocular features (conjunctivitis) were not included. In total, 42 publications with 66 cases met the criteria. The most frequent descriptive features included maculopapular (59%), lower limb petechial purpura (11%) and erythematous/red (9%). Pruritus was described in 44% and tenderness in 3%. Lesions

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2018 Clinical & Experimental Dermatology

5. Malar Rash

Malar Rash Malar Rash Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Malar Rash Malar Rash Aka: Malar Rash II. Pathophysiology Immune (...) -mediated erythematous rash III. Signs Sun sensitive, erythematous rash Butterfly-shape appearance Involves both cheeks and variably the bridge of nose IV. Causes (SLE) infection (or slapped cheek) Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Malar Rash." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Butterfly rash (C0277942) Concepts Finding

2015 FP Notebook

6. Systemic lupus erythematosus

the skin and joints, although serositis, nephritis, haematological cytopenias, and neurological manifestations may occur during the course of the disease. Earlier diagnosis and better management have resulted in a lower prevalence of life-threatening disease. History and exam malar (butterfly) rash photosensitive rash discoid rash fatigue weight loss fever oral ulcers alopecia arthralgia/arthritis fibromyalgia Raynaud's phenomenon chest pain and shortness of breath hypertension signs of nephrosis (e.g

2018 BMJ Best Practice

9. CRACKCast E174 – Genitourinary and Renal Tract Disorders

be reduced by the disease. Usually broken down by two age groups: < 5 yrs – likely primary nephrotic syndrome – due to minimal change disease > 5 yrs – usually due to a secondary/systemic disease PSGN Lupus Here’s that list of causes: Primary proteinurea due to minimal change disease primary nephrotic syndrome (no gross hematuria or elevated creatinine level, normal complement levels, and no evidence of extrarenal causes such as a malar rash) Secondary causes: IgA nephropathy PSGN HUS HSP Lupus (...) a strep infection (can be provoked by any virus) classic HSP rash is usually diagnostic. Watch for renal or abdominal complications. These folks can become sick fast! ● Aggressive supportive care ○ Correct electrolytes ○ Treat pancreatic failure ○ Treat seizures ○ Treat hypertension ● No role for antibiotics (enhance release of verotoxin) Except: Pneumococcal-associated HUS often presents with pneumonia and should be treated ● Early consideration of dialysis ● PRBCs if Hgb < 60 ● ?consideration

2018 CandiEM

10. CRACKCast E118 – SLE and Vasculitides

levels · Direct coombs test positive Table 108.1 is very busy – Remember the only mnemonic from med school SOAP BRAIN MD Serositis Oral Ulcers Arthritis Photosensitivity & Pulmonary Fibrosis Blood cells (pancytopenia) Renal, Raynauds ANA Immunologic (anti-Sm, anti-dsDNA) Neuropsych Malar Rash Discoid Rash [3] List drugs that induce lupus See Box 108.2 from Rosens 8 th Edition – SLE and Vasculitides Drugs Definitively Implicated in Causing Drug-Induced Lupus Procainamide Hydralazine Methyldopa (...) Wise Cracks [1] What is the differential for SLE patient and Chest pain? See Table 108.2 Rosens 9 th Edition – SLE and Vasculitides Pleuritis Pulmonary embolism Pneumonia Pericarditis Coronary artery disease [2] Name and identify 2 pathognomonic clinical features for lupus Malar Rash & Discoid Lupus [3] When should rheumatology be involved in the ED with a SLE patient? Hold up – your SLE patient is not just an automatic turf to CTU! Here is an important list to consider from box 108.3 in Rosens 8

2017 CandiEM

11. Guideline for the management of adults with Systemic Lupus Erythematosus

case series [ , ]; 2 SRs [ , ] NSAIDs Symptom control in mild non-renal lupus only 1 3 D 1 SR covers case series/reports [ ] Sunscreen (high-SPF UV-A and UV-B) Prevents UV-induced rashes and other manifestations 7 2 ++ B 1 blind RCT [ ]; 5 cohort studies [ ]; 1 case series [ ] Low-dose oral prednisolone (≤7.5 mg) Mild lupus and to prevent flares 0 4 D Expert opinion Higher doses of oral prednisolone ≤0.5 mg/kg/day Moderate lupus and prevention of flares 0 2 4 2+ D C To prevent flare: 1 blind RCT (...) [ ] Tacrolimus 1–3 mg/day (assess drug levels) Moderate/severe lupus, steroid-sparing 3 3 D 2 cohort studies [ , ]; 1 SR [ ] LEF (20 mg/day) Moderate lupus without subacute rash 3 3 D 1 small blind RCT [ ]; 1 cohort study [ ]; 1 SR [ ] CYC (see text for dosing) Severe lupus, including NPSLE, prevent flare, steroid-sparing 30 2 ++ B 4 open-label RCTs [ ]; 25 cohort studies covered by 1 SR [ ] Rituximab 1000 mg × 2 Refractory severe and moderate lupus; steroid-sparing 33 2+ C 1 blind RCT [ , ]; 3 open-label

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2017 British Society for Rheumatology

12. A rare case of suicidal ideation related to Adalimumab use (PubMed)

) and no known prior history of systemic lupus erythematosus or depression presented with suicidal ideations, joint pains and a malar rash after a recent change in her Adalimumab dose. She was treated for an acute ATIL episode based on her symptoms and serologies which were positive for anti-double-stranded deoxyribonucleic acid antibody. An inpatient psychiatric consultation determined that the patient's suicidal ideations may be an associated symptom of her current ATIL episode or possibly secondary to her

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2018 Open access rheumatology : research and reviews

13. Whom should you test for secondary causes of hypertension?

, malar rash); or laboratory analysis (elevated serum creatinine, low thyroid-stimulating hormone) (SOR: C, consensus-based guidelines). Patients with undifferentiated resistant hypertension should receive further directed evaluation for secondary causes (SOR: C, consensus-based guidelines). URI Citation Journal of Family Practice, 63(1) 2014: 41-42, 54. Rights OpenAccess. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. Collections hosted by hosted by

2014 Clinical Inquiries

14. How to Answer Board-Style Multiple-Choice Questions Like a Boss

because the absolute nature of these terms doesn’t match the real-life uncertainty of clinical medicine. On the other hand, descriptors such as “usually normal” may be too vague to be listed in a correct answer: A 19-year-old woman notes a malar, photosensitive rash and wrist arthralgias. Heart and lung exams are normal. White blood cell count is 2.6 K/mcl, hemoglobin is 9.2 g/dl, and platelets are 36 K/mcl. A diagnosis of lupus is MOST LIKELY in this patient for which of the following reasons (...) ? A. Malar rash is always diagnostic of lupus. B. Pancytopenia may be associated with lupus. C. Pulmonary exam findings are never normal in lupus. D. Joint exam findings are usually normal in lupus. E. All of the above. While these strategies can’t substitute for true understanding, they may help you avoid some common pitfalls in answering MCQs. Good luck on the boards! “Superficially, it might be said that the function of the kidneys is to make urine; but in a more considered view one can say

2018 Renal Fellow Network

15. Seborrheic area involvement in patients with systemic lupus erythematosus. (PubMed)

Seborrheic area involvement in patients with systemic lupus erythematosus. The most characteristic skin manifestation of systemic lupus erythematosus (LE) is malar rash characterized by an erythematous congestive sometimes secondarily squamous eruption over the cheeks and nasal bridge, that typically spares nasolabial folds. This rash is referred to as "acute cutaneous lupus erythematosus" (ACLE) (1). Recently, 2 SLE patients with remarkable skin involvement of seborrheic area (SA) came to our

2019 Journal of the European Academy of Dermatology and Venereology

16. Lupus Podocytopathy

in subsequent clinic visits. I find Lupus Nephritis most fascinating among all the GNs. One of the most interesting cases I saw since the beginning of fellowship was of a 36 yrs. old woman who presented with joint pain, malar rash, photosensitivity, worsening generalized edema and nephrotic range proteinuria of 8 grams. She had 2 prior renal biopsies- one with a diagnosis of Minimal Change Disease and the second one 2 years ago with FSGS tip lesion and Class 2 lupus Nephritis. On her current presentation

2017 Renal Fellow Network

17. Guidelines for the treatment of malaria. Third edition

2014; 6:CD008152. doi: 10.1002/14651858.CD008152.pub3. White NJ, Qiao LG, Qi G, Luzzatto L. Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common. Malar J 2012;11:418. 4 | Treatment of uncomplicated Plasmodium falciparum malaria 42 Guidelines for the treatment of malaria 3 RD EDITIONThe population benefits of reducing malaria transmission with gametocytocidal drugs such as primaquine require that a very high

2015 World Health Organisation Guidelines

18. Management of Dengue Infection in Adults

pathophysiological changes during each phase of the disease will produce a rational approach in the management of dengue infection. 3.2 CLINICAL COURSE OF DENGUE INFECTION After the incubation period, the illness begins abruptly and will be followed by three phases: febrile, critical and recovery phase (refer to Figure 5). 2,3 i. Febrile Phase Patients develop high grade fever suddenly and usually last 2-7 days. It is often accompanied by facial flushing, rash, generalised body ache, vomiting and headache. 2,3 (...) than the level of alanine aminotransaminase (ALT)], hypoproteinaemia and hypoalbuminaemia are usually observed. 2-4 iii. Recovery/Reabsorption Phase After 24-48 hours of critical phase, usually plasma leakage stops followed by reabsorption of extravascular fluid. Patient’s general well being improves, appetite returns, gastrointestinal symptoms improve, haemodynamic status stabilises and diuresis ensues. Some patient may have a classical rash of “isles of white in the sea of red” with generalised

2015 Ministry of Health, Malaysia

20. Systemic lupus erythematosus

, NO. 10 OCTOBER 2013 697 Cutaneous manifestations The spectrum of cutaneous manifestations of lupus erythematosus (LE) is broad, but the most classical forms associated with systemic LE are the acute malar and chronic discoid lupus erythematosus (DLE) rash. Both can be quite photosensitive in nature. 15,16 Acute malar rash is a slightly raised erythematous rash of the face, particularly cheeks and nose, with nasolabial sparing, known as the ‘butterfly’ rash. A worsening of the rash usually accompanies (...) a flare of systemic disease. Sometimes a more generalised form over the body is present. DLE are characterised by slightly raised, scaly lesions that have a potential to scar. They can be found commonly on the scalp and face, and less commonly over the limbs and trunk. Only 5% of people with DLE have SLE, but conversely among individuals with SLE, 20% will have DLE. 17 Subacute cutaneous lupus erythematosus is another lupus-specific rash. It is a common skin manifestation in drug-induced lupus

2014 Clinical Practice Guidelines Portal

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