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Macule

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161. A cross-sectional study of sweat-induced dermatitis during a South Indian summer: a glimpse of sweat gland-mediated cutaneous inflammation. (PubMed)

dermatitis" presenting with dry, hyperpigmented, fissured "parchment"-like skin, shiny "crinkled cellophane paper"-like skin, or asymptomatic hyperpigmented macules was seen. Other atypical presentations included miliaria pustulosa with "hypopyon sign" and "linear and parallel ridge pattern" of dermatitis in patients with miliaria rubra affecting the lower neck and upper chest.A wide spectrum of sweat-induced dermatitis was seen during the summer months in a tropical region. It reflects the role

2018 International Journal of Dermatology

162. Diagnostic challenges in a child with early onset desmoplastic medulloblastoma and homozygous variants in MSH2 and MSH6. (PubMed)

macules and other pigmentation alterations. We report on a 13-month-old girl suspected of having CMMRD due to a desmoplastic medulloblastoma and a striking skin pigmentation that included multiple café-au-lait macules, hypopigmented areas and Mongolian spots. Whole-exome sequencing revealed homozygosity for MSH2 variant p.(Leu92Val) and MSH6 variant p.(Val809del), both variants of uncertain significance (VUS). Immunohistochemical analysis of the tumour tissue showed expression of all four MMR proteins

2018 European Journal of Human Genetics

163. The endovascular management of neurofibromatosis-associated aneurysms: A systematic review.

The endovascular management of neurofibromatosis-associated aneurysms: A systematic review. Neurofibroblastoma (NF) or Von Recklinghausen disease, is an autosomal dominant disorder affecting one in 3000 individuals. Cardinal features of NF include multiple café-au-lait macules, benign neurofibromas, and iris hamartomas. Albeit less common, vascular lesions of medium and large-sized arteries and veins are a well-recognized complication, which can lead to fatal consequences such as rupture.A

2018 European journal of radiology

164. Blaschko-linear “Congenital Mixed Hemato-lymphangio-keratoma Serpiginosum” Naeviforme: A New Hybrid Entity or Various Morphological Reflections of the Two Different Vascular Abnormalities? (PubMed)

-yellowish papules; 3) bright-red grouped papules; 4) keratotic-surfaced grouped dark-red papules; and 5) patchy, punctate, and erythematous red macules. All of the lesions were intertwined along the lines of Blaschko and were in the form of irregular serpiginous plaques. Histopathological examinations of the lesions showed three main histological features, and diagnoses of the lesions were made as lymphangioma circumscriptum, lymphangiokeratoma, and verrucous hemangioma. To the best of our knowledge

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2018 The Journal of clinical and aesthetic dermatology

165. P-Phenylenediamine Hair Dye Allergy and Its Clinical Characteristics (PubMed)

between July 2009 and March 2015. Clinical symptoms, signs, associated skin diseases, involved ACD area, and patterns of hair dye use were obtained by reviewing medical records and by interview.HDCA was more common in women and in individuals aged more than 50 years. Pruritus was the most common symptom; erythematous macules and patches were the most frequently observed clinical signs. The most common site of HDCA was the face and non-specific eczema and urticaria were frequently observed with HDCA

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2018 Annals of dermatology

166. Acquired Brachial Cutaneous Dyschromatosis in a Middle Aged Male (PubMed)

Acquired Brachial Cutaneous Dyschromatosis in a Middle Aged Male Acquired brachial cutaneous dyschromatosis (ABCD) is an acquired disorder of pigmentary change that presents as chronic, asymptomatic, geographic-shaped, gray-brown patches, consisting of mixed hyper and hypopigmented macules on the dorsal aspect of the forearms. We report a case of a 40-year-old male who presented with asymptomatic, multiple brown-colored macules on the outer aspects of both arms. He had no history (...) of hypertension and had never taken angiotensin converting enzyme inhibitors. He also denied chronic sun exposure history. Histologic examination demonstrated epidermal atrophy, increased basal layer pigmentation, and several telangiectatic vessels in the upper dermis. Solar elastosis was not remarkable. The patient's clinical and histopathologic features were consistent with a diagnosis of ABCD. Poikiloderma of Civatte, melasma, acquired bilateral telangiectatic macules and other pigmentary disorders should

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2018 Annals of dermatology

167. Which egg features predict egg rejection responses in American robins? Replicating Rothstein's (1982) study (PubMed)

evaluated with replication. Here, we partially replicated Rothstein's (1982) experiments using parallel artificial model egg treatments to simulate cowbird (Molothrus ater) parasitism in American robin (Turdus migratorius) nests. We compared our data with those of Rothstein (1982) and confirmed most of its original findings: (1) robins reject model eggs that differ from the appearance of a natural robin egg toward that of a natural cowbird egg in background color, size, and maculation; (2) rejection (...) of cowbird eggs. Future work on egg recognition will benefit from utilizing a range of model eggs varying continuously in background color, maculation patterning, and size in combination with avian visual modeling, rather than using model eggs which vary only discretely.

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2018 Ecology and evolution

168. Eruptive lentiginosis in resolving psoriatic plaques (PubMed)

Reports Retracted Publication 2018 03 31 United States JAAD Case Rep 101665210 2352-5126 JAAD Case Rep. 2018 Sep 18;4(8):841 30238053 ELRP, eruptive lentiginosis in resolving psoriatic plaques IL, interleukin TNF, tumor necrosis factor hyperpigmentation lentigines macules plaque psoriasis 2018 4 26 6 0 2018 4 26 6 0 2018 4 26 6 1 epublish 29693059 10.1016/j.jdcr.2017.10.009 S2352-5126(17)30261-8 PMC5911780 Pigment Cell Melanoma Res. 2012 Mar;25(2):219-30 22136309 Clin Exp Dermatol. 2006 Mar;31(2):298

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2018 JAAD Case Reports

169. Nevus anemicus and RASopathies (PubMed)

, University Hospital Leuven, Leuven, Belgium. Department of Human Genetics, KU Leuven, Leuven, Belgium. eng Case Reports 2018 04 06 United States JAAD Case Rep 101665210 2352-5126 CALMs, café au lait macules Legius syndrome MAPK, mitogen-activated protein kinase NF1, neurofibromatosis type 1 Noonan syndrome PTPN11, protein tyrosine phosphatase nonreceptor type 11 RAF1, rapidly accelerated fibrosarcoma-1 RAS, rat sarcoma family of protooncogenes RASopathy SPRED1, sprouty-related, EVH1 domain containing

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2018 JAAD Case Reports

170. Peutz-Jeghers Syndrome Presenting as Colonic Intussusception: A Rare Entity (PubMed)

Peutz-Jeghers Syndrome Presenting as Colonic Intussusception: A Rare Entity Peutz-Jeghers syndrome is an autosomal dominant inherited medical condition characterized by hyperpigmented mucocutaneous macules, hamartomatous polyps in the digestive tract, and with a greater risk of gastrointestinal and non-gastrointestinal cancers. In fact, without appropriate medical surveillance, the lifetime risk for all cancers combined may be as high as 93%. The syndrome is rare, with estimates of incidence

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2018 Gastroenterology research

171. Early diagnosis of tuberous sclerosis complex: a race against time. How to make the diagnosis before seizures? (PubMed)

for early diagnosis.82/100 children were diagnosed with TSC within the first 4 months of life. Apart from cardiac tumors, the most frequently observed early TSC signs were subependymal nodules (71/100, 71%), cortical dysplasia (66/100, 66%), and hypomelanotic macules (35/100, 35%). The most useful clinical studies for early TSC diagnosis were brain magnetic resonance imaging (MRI), skin examination and echocardiography. Genetic testing was performed in 49/100 of the patients, but the results were

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2018 Orphanet journal of rare diseases

172. An unusual lesion on the nose: microvenular hemangioma (PubMed)

cases revealed that 15% of MVH patients were over 40 years of age and only 3% of the cases showed macules or patches. A literature survey showed only two cases of MVH located on the facial region, one on the chin and the other on the cheek. Our case was unique for its location and interesting for other rarely encountered features. MVH should be considered in the differential diagnoses of vascular lesions on nasal skin.

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2018 Dermatology practical & conceptual

173. A secondary syphilis rash with scaly target lesions (PubMed)

virus positive. The characteristic rash of secondary syphilis may appear as maculopapular, evolving initially from macules to small reddish-brown papules with minor scaling later. When the scaling is prominent, lesions can be difficult to differentiate from guttate psoriasis. Typical target lesions are most often associated with erythema multiforme, but they can rarely occur in secondary and congenital syphilis. Syphilis should be suspected in high-risk patients presenting a variety of atypical

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2018 Oxford Medical Case Reports

174. Vestibular Injury After Low-Intensity Blast Exposure (PubMed)

damage to both the peripheral and central vestibular system; similar to previous findings that blast exposure results in damage to auditory receptors. In this study, mice were exposed to a 63 kPa peak blast-wave over pressure and were examined for vestibular receptor damage as well as behavioral assays to identify vestibular dysfunction. We observed perforations to the tympanic membrane in all blast animals. We also observed significant loss of stereocilia on hair cells in the cristae and macule up

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2018 Frontiers in neurology

175. Unilateral Focal Dermal Hypoplasia (Goltz Syndrome): Case Report and Literature Review (PubMed)

-reticulated atrophic macules and patches in a linear pattern distributed along the lines of Blaschko over the right side of the face and the right arm. Also she is having hypoplasia of the right breast with dental enamel abnormality and partial anodontia in the lower jaw. Sparse hair and partial alopecia on the right side (scalp, eyebrows, and eyelashes) were also observed.

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2018 Case reports in dermatology

176. Spontaneous splenic rupture complicating primary varicella zoster infection: a case report (PubMed)

, presented with a 2 day history of sudden onset, worsening generalised abdominal pain and a 1 day history of vomiting. The following day he developed fevers and a generalised widespread erythematous rash consisting of clusters of macules, papules and vesicles at different stages of development. There was no history of sore throat, coryza, arthralgia, myalgia, cough, shortness of breath, weight loss, or night sweats. There was no recent illness and no history of trauma. CT abdomen showed splenic rupture

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2018 BMC research notes

177. Epidermodysplasie verruciforme: à propos d’un cas (PubMed)

Epidermodysplasie verruciforme: à propos d’un cas Epidermodysplasia verruciformis, also known as Lewandowsky-Lutz syndrome or tree man disease is a rare genetic skin disorder. It is characterized by abnormal susceptibility of the skin coating to human papillomaviruses (HPVs). It commonly affects people between the ages of 4 and 8, most often before the age of 20 years but it may exceptionally occur later. It is characterized by the appearance of scaly macules and sometimes exuberant

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2018 The Pan African medical journal

178. Association rare: lichen scléroatrophique extragénital et vitiligo inflammatoire chez un enfant (PubMed)

Association rare: lichen scléroatrophique extragénital et vitiligo inflammatoire chez un enfant Scleroatrophic lichen (SL) and vitiligo are two depigmenting disorders which may occur separately or, rarely, in combination. Their association may seem logical because both these disorders are characterized by the suspicion of an autoimmune pathogenesis. We here report the case of a 8-year old girl, with no notable medical history, presenting with achromic macules and papular nonpruritic lesions (...) evolving over 6 months. Clinical examination showed two types of lesions (A): ovalaire achromic macules measuring 1-3 cm along their longer axis, located at the level of the front, of the neck, of the shoulders, as well as of the peri-mamelonar and of the genital region. These lesions exhibited slightly raised peripheral inflammatory border as well as a poliosis. The patient also had pearly white atrophic papular plaques at the level of the interscapular and abdominal regions as well as of the anterior

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2018 The Pan African medical journal

179. Atypical tuberous sclerosis complex presenting as familial renal cell carcinoma with leiomyomatous stroma (PubMed)

Atypical tuberous sclerosis complex presenting as familial renal cell carcinoma with leiomyomatous stroma We report an atypical tuberous sclerosis complex (TSC) phenotype presenting as familial multiple renal cell carcinomas (RCCs) with (angio)leiomyomatous stroma (RCCLS) (5/7 familial RCCs) on a background of multiple angiomyolipomas, hypopigmented skin macules, and absence of neurological anomalies. In the index case and three relatives, germline genetic testing identified a heterozygous TSC2

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2018 The Journal of Pathology: Clinical Research

180. Clinical Features and Treatment Outcomes among Children with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A 20-Year Study in a Tertiary Referral Hospital (PubMed)

patients (M : F, 16 : 20) with the mean age of 9.2 ± 4.0 years were identified. There were 20 cases of SJS, 4 cases of SJS-TEN overlap, and 12 cases of TEN. Drugs were the leading cause for the diseases (72.3%); antiepileptics were the most common culprits (36.1%). Cutaneous morphology at presentation was morbilliform rash (83.3%), blister (38.9%), targetoid lesions (25.0%), and purpuric macules (2.8%). Oral mucosa (97.2%) and eye (83.3%) were the 2 most common mucosal involvements. Majority

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2018 Dermatology research and practice

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