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Macule

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1301. Atrophying tinea versicolor: a clinical and histological study of 12 patients. (Abstract)

, alcian blue-PAS and PAS-diastase preparations.Five men and seven women aged 17-73 years in whom lesions characterized as atrophic plaques, patches or macules prompted clinical differential diagnoses including parapsoriasis or mycosis fungoides (MF), anetoderma, lupus erythematosus, and steroid atrophy. A LM examination showed epidermal colonization with pityrosporum hyphae and spores accompanied by variable epidermal and dermal atrophy characterized by rete-ridge effacement, subepidermal fibroplasia

2003 International Journal of Dermatology

1302. Lepromatous leprosy and reversal reaction in a Micronesian immigrant. (Abstract)

Lepromatous leprosy and reversal reaction in a Micronesian immigrant. A 25-year-old Micronesian man from the island of Otia developed erythematous plaques on his legs. He was diagnosed with erythema nodosum and treated with systemic prednisone. Two months later, he presented with erythematous nodules on his forehead, cheeks, and chin (Fig. 1). Examination revealed scattered violaceous papules on his chest, arms, forearms, hands, and feet, and deep purple macules on his palms and soles

2003 International Journal of Dermatology

1303. Guttate morphoea in human T-cell lymphoma/lymphotrophic virus type-1 (HTLV-1) infection. (Abstract)

Guttate morphoea in human T-cell lymphoma/lymphotrophic virus type-1 (HTLV-1) infection. A 62-year-old Japanese man presented with multiple small atrophic macules on the trunk and extremities. The lesions were discrete, oval in shape and enclosed by lilac ring. They were distributed in a Christmas tree distribution, reminiscent of pityriasis rosea. Skin biopsy showed increased collagen fibres in the dermis and invading subcutaneous tissue. The clinico-pathological features were consistent

2003 Clinical & Experimental Dermatology

1304. Kikuchi-Fujimoto disease with papulopustular skin manifestations. (Abstract)

Kikuchi-Fujimoto disease with papulopustular skin manifestations. Kikuchi-Fujimoto disease commonly presents with cervical lymphadenopathy accompanied by fever, myalgia, neutropaenia, and rarely cutaneous eruption. Most cutaneous lesions present as erythematous macules, papules, plaques, nodules, or ulcers on the upper part of the body such as trunk, upper extremities, and face. We present a case of Kikuchi-Fujimoto disease with a papulopustular eruption on the whole body including the lower

2003 Clinical & Experimental Dermatology

1305. Dyschromatosis universalis hereditaria. (Abstract)

Dyschromatosis universalis hereditaria. Dyschromatosis universalis hereditaria is a clinically heterogenous disorder. We report two unrelated Indian patients with dyschromatosis universalis hereditaria, who had generalized and progressive reticulate hyper- and hypo-pigmentation of the skin. The oral mucosa and tongue also showed mottled pigmentation. Intriguingly, the palms and soles were also affected with a diffuse hyper-pigmentation interspersed with spotty de-pigmented macules. Dystrophic

2002 Clinical & Experimental Dermatology

1306. A family with seizures and minor features of tuberous sclerosis and a novel TSC2 mutation. (Abstract)

A family with seizures and minor features of tuberous sclerosis and a novel TSC2 mutation. The authors studied nine members of a family that demonstrated a limited form of tuberous sclerosis complex (TSC). Cutaneous findings were limited to hypopigmented macules in four patients. Five family members had recurrent seizures, and three of these had migrational defects of the cerebral mantle. Mutational analysis of TSC2 indicated the presence of the novel missense change 3106T-->C, 1036S-->P in all

2003 Neurology

1307. Cutaneous angiosarcoma of the scalp: a multidisciplinary approach. Full Text available with Trip Pro

with a median age of 71.0 years. Most patients presented after a delay in diagnosis with either a bruise-like macule (48.3%) or a nonbruise-like nodule (51.7%). Seventy-five percent of patients had pathologic Stage T2 disease, and 76% of patients had high-grade tumors. Virtually all patients underwent surgical excision (96.6%); however, negative surgical margins were achieved in only 21.4% of patients. Multiple lesions on presentation were associated with a shorter time to recurrence (P = 0.02). The median

2003 Cancer

1308. Acquired digital arteriovenous malformation: a report of three cases and study with epiluminescence microscopy. (Abstract)

Acquired digital arteriovenous malformation: a report of three cases and study with epiluminescence microscopy. Acquired digital arteriovenous malformation is an abnormal connection between the arteriole and venule in the finger, fed by the digital vessels. Lesions are characterized by small, slightly raised dark-red macules on the distal part of the fingers. In the past, similar cases had been described using the terms 'cutaneous keratotic haemangioma' and 'periungual and subungual

2002 British Journal of Dermatology

1309. Melanocyte detachment after skin friction in non lesional skin of patients with generalized vitiligo. (Abstract)

Melanocyte detachment after skin friction in non lesional skin of patients with generalized vitiligo. In vitiligo, melanocytes are gradually lost in depigmented macules of the skin. The disappearance of melanocytes has, however, not been clearly observed and consequently the aetiology of the disease (autoimmune, neural, cytotoxic) is still elusive. The starting point of vitiligo macules is frequently determined by local conditions such as wounds and excoriations, but may also follow minor

2003 British Journal of Dermatology

1310. Increased procollagen alpha1(I) mRNA expression by dermal fibroblasts in melorheostosis. (Abstract)

Increased procollagen alpha1(I) mRNA expression by dermal fibroblasts in melorheostosis. We report a patient with melorheostosis in whom increased procollagen alpha1(I) mRNA expression and alpha1(I), alpha2(I) and alpha1(III) collagen secretion were observed in dermal fibroblasts obtained from a skin biopsy overlying the involved bone. The patient was a 53-year-old man with melorheostosis lesions over the left knee joint. Multiple pigmented macules were present on the medial aspect of the lower

2003 British Journal of Dermatology

1311. Recurrent 'sterile' verrucous cyst abscesses and epidermodysplasia verruciformis-like eruption associated with idiopathic CD4 lymphopenia. (Abstract)

and interferon-gamma treatment was instituted for interstitial lung disease. Cultures were consistently negative for microorganisms, but pathological examination revealed ruptured epidermoid cyst walls with human papillomavirus (HPV) viropathic changes (keratinocytes with perinuclear halos and abundant basophilic keratohyaline granules). Cutaneous examination showed numerous, widespread flat-topped papules and achromic macules over the extremities, head and neck. Nested polymerase chain reaction analysis

2003 British Journal of Dermatology

1312. Cutaneous manifestations of hemophagocytic lymphohistiocytosis. (Abstract)

and "maculopapular." The aim of this report is to better delineate the cutaneous manifestations of the disorder to assist in differentiating the process from other systemic diseases.A case report of a neonate with hemophagocytic lymphohistiocytosis with generalized purpuric macules is described. The clinical features of 5 other patients with hemophagocytic lymphohistiocytosis at Children's Hospital of Wisconsin, Milwaukee, are summarized. Clinical images of 1 additional neonatal patient with hemophagocytic (...) lymphohistiocytosis are presented as well. These observations demonstrate the varied cutaneous manifestations of hemophagocytic lymphohistiocytosis: erythroderma, generalized purpuric macules and papules, and morbilliform eruptions.Awareness of cutaneous involvement can assist in the initial diagnosis of hemophagocytic lymphohistiocytosis and potentially signify recurrences.

2002 Archives of Dermatology

1313. Effect of cold air cooling on the incidence of postinflammatory hyperpigmentation after Q-switched Nd:YAG laser treatment of acquired bilateral nevus of Ota like macules. Full Text available with Trip Pro

Effect of cold air cooling on the incidence of postinflammatory hyperpigmentation after Q-switched Nd:YAG laser treatment of acquired bilateral nevus of Ota like macules. To investigate the effect of cold air cooling on the incidence of postinflammatory hyperpigmentation (PIH) after laser treatment in Asian patients.Randomized, controlled, split-face study.Skin laser center of a university hospital.Twenty-three Thai women with acquired bilateral nevus of Ota-like macules.Patients were treated

2007 Archives of Dermatology Controlled trial quality: uncertain

1314. A case of agminated lentiginosis with multiple café-au-lait macules. (Abstract)

A case of agminated lentiginosis with multiple café-au-lait macules. Agminated lentiginosis is an unusual pigmentary disorder, characterized by numerous lentigines grouped within an area of normal skin. The pigmented macules are often in a segmental distribution within a sharp demarcation at the midline. We encountered a 28-year-old woman with an unusual combination of multiple café-au-lait macules and diffuse numerous lentigines involving the right cheek and ipsilateral upper thorax with sharp (...) demarcation at the midline. The multiple lentigines extended bilaterally over the back in a peppered distribution. There were 21 café-au-lait macules on both arms, and the trunk and buttocks; however, there were no Lisch nodules, neurofibromas, or any other clinical manifestations for neurofibromatosis. Histopathology of a macule revealed the features of lentigo.

2007 Clinical & Experimental Dermatology

1315. Ipsilateral café-au-lait macules, deafness, and pituitary microadenoma in a 35-year-old woman. (Abstract)

Ipsilateral café-au-lait macules, deafness, and pituitary microadenoma in a 35-year-old woman. The association between ipsilateral café-au-lait macules, deafness, and pituitary adenoma has not been described previously.A 35-year-old woman affected since birth with two café-au-lait macules, one measuring 15 x 20 cm, with an irregular shape, covering almost all of the left buttock, and the other measuring 6 x 13 cm on the front side of the left thigh, is described. For as long as the patient can

2008 International Journal of Dermatology

1316. Giant café-au-lait macule in neurofibromatosis 1: a type 2 segmental manifestation of neurofibromatosis 1? (Abstract)

Giant café-au-lait macule in neurofibromatosis 1: a type 2 segmental manifestation of neurofibromatosis 1? Type 2 segmental manifestation of autosomal dominant dermatoses refers to pronounced segmental lesions superimposed on the ordinary nonsegmental phenotype, indicating loss of heterozygosity occurring at an early stage of embryogenesis. We describe a 20-year-old Taiwanese woman with typical lesions of neurofibromatosis type 1 (NF1) in the form of characteristic café-au-lait spots (...) , neurofibromas, axillary freckling and Lisch nodules. In addition, a giant garment-like or "bathing-trunk" café-au-lait macule involved the lower half of the trunk, the buttocks, and parts of the thighs, being superimposed on the ordinary smaller spots of NF1. This large café-au-lait macule may be best explained as an example of type 2 segmental NF1. A novel mutation (3009delG) in exon 23 was also identified in this patient, which has not yet been described in sporadic and familial NF1.

2008 Journal of American Academy of Dermatology

1317. Brown macules on the cheeks Full Text available with Trip Pro

Brown macules on the cheeks 15794019 2005 04 22 2018 11 13 0008-350X 51 2005 Mar Canadian family physician Medecin de famille canadien Can Fam Physician Can you identify this condition? Melasma. 353-5 Ting Patricia T PT University of Calgary, Alberta. Barankin Benjamin B eng Case Reports Journal Article Review Canada Can Fam Physician 0120300 0008-350X IM Addison Disease diagnosis Adult Diagnosis, Differential Female Humans Lentigo diagnosis Lupus Erythematosus, Discoid diagnosis Melanosis

2005 Canadian Family Physician

1318. Carney complex presenting with Raynaud's phenomenon and erythematous macules of the extremities. (Abstract)

Carney complex presenting with Raynaud's phenomenon and erythematous macules of the extremities. A 12-year-old male presented with a 6-week history of apparent digital vasculitis with color changes of the distal fingers and erythematous macules of the palms and soles. Physical examination revealed skin findings of Carney complex and an abnormal cardiac examination. Echocardiography demonstrated a large left atrial mass, which caused partial obstruction during diastole and moderate mitral valve

2006 Pediatric Cardiology

1319. Treatment of acquired bilateral nevus of ota-like macules (Hori's nevus) with a combination of the 532 nm Q-Switched Nd:YAG laser followed by the 1,064 nm Q-switched Nd:YAG is more effective: prospective study. (Abstract)

Treatment of acquired bilateral nevus of ota-like macules (Hori's nevus) with a combination of the 532 nm Q-Switched Nd:YAG laser followed by the 1,064 nm Q-switched Nd:YAG is more effective: prospective study. Acquired bilateral nevus of Ota-like macules (Hori's nevus) is a common dyschromatosis among Asian women. Q-switched lasers have been used successfully as a treatment modality.The purpose of this study was to compare the efficacy of using the Q-switched 532 nm neodymium:yttrium-aluminum

2006 Dermatologic Surgery

1320. Divided café-au-lait macule of the mouth. (Abstract)

Divided café-au-lait macule of the mouth. We describe a 4-year-old, otherwise healthy boy with a congenital history of a perioral and labial segmental café-au-lait macule, who was noted to have unilateral localized gingival hyperpigmentation that aligned with the café-au-lait macule. This case is highly illustrative of the embryologic timing of the genetic event locally, which leads to café-au-lait type hyperpigmentation. Because the facial features and the ectoderm overlying the facial muscles (...) develop around the third to fourth week of gestation, the distribution of this café-au-lait macule suggests development at the same time.

2007 Journal of American Academy of Dermatology

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