How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,317 results for

Macule

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

102. Meningitis - bacterial meningitis and meningococcal disease

of meningococcal disease? When a non-blanching rash is present , it may appear as a: Scanty petechial rash (red or purple non-blanching macules smaller than 2 mm in diameter). Purpuric (haemorrhagic) rash (spots larger than 2 mm in diameter) — this may be absent in the early phase of the illness and may initially be blanching or macular in nature. Images of petechial, purpuric, and meningococcal rashes can be found in the document by the Meningitis Research Foundation (available at ). Examine the whole body

2019 NICE Clinical Knowledge Summaries

103. Seborrhoeic dermatitis

). Inflammation may occur in the ear canals, the cup of the ear and behind the ears. Seborrhoeic dermatitis in the beard area can present similarly to that on the scalp. Upper chest and back — different forms of seborrhoeic dermatitis may be apparent: Petaloid type — in men petal-shaped lesions typically develop on the presternal area. Pityriasiform type (less common) — generalized macules and patches that resemble extensive pityriasis rosea. Flexures and skin folds (in particular axillae, groin, anogenital

2019 NICE Clinical Knowledge Summaries

104. Quality of life of adult vitiligo patients using camouflage: A survey in a Chinese vitiligo community. (PubMed)

Quality of life of adult vitiligo patients using camouflage: A survey in a Chinese vitiligo community. Vitiligo is an acquired depigmented skin disease resulting in white macules, which may significantly impair the quality of life (QoL) of the patients.To estimate the QoL in Chinese vitiligo patients using camouflage with a more detailed description, and to identify the possible risk factors related to poor QoL.An online survey was conducted in vitiligo patients using camouflage from a vitiligo

Full Text available with Trip Pro

2019 PLoS ONE

108. Public health guidance on varicella vaccination in the European Union

adulthood. Infection from primary varicella usually confers lifetime immunity. The life-time risk of developing HZ was calculated to be 28% for England and Wales [30]. It is more usual in immunocompromised patients and patients over 50 years, and is unusual in children [31]. Varicella is characterised by fever and a generalised, pruritic, vesicular rash, typically consisting of 200 to 500 lesions in varying stages of development and resolution. The rash progresses rapidly from macules to papules

2015 European Centre for Disease Prevention and Control - Public Health Guidance

109. The effect of melasma on self-esteem: A pilot study (PubMed)

The effect of melasma on self-esteem: A pilot study Melasma is a common disorder of hyperpigmentation characterized by tan or brown macules and patches affecting sun-exposed areas, particularly the face. Melasma has been shown to have a significant impact on the quality of life and self-esteem of those affected. We interviewed six patients who were diagnosed with moderate-to-severe melasma with regard to the effect of their disorder on their self-esteem. All patients reported a significant

Full Text available with Trip Pro

2017 International journal of women's dermatology

110. Fungal skin infection - body and groin

of atopy. See the CKS topic on for more information. Pityriasis rosea — multiple circular or oval pink-red or fawn-coloured slightly scaly lesions, typically in a symmetrical distribution affecting the trunk and proximal limbs. A larger herald patch usually precedes the onset of the generalized rash. See the CKS topic on for more information. Pityriasis versicolor — well-demarcated multiple round or oval macules of variable colours most commonly on the back, chest, and upper arms. Surface may have (...) : Intertrigo — superficial skin inflammation occurring on two closely-opposed skin surfaces, such as the skin folds. May be due to mechanical causes (such as moisture, friction, or heat), and may have secondary bacterial or candidal infection. The rash is usually uniformly red without central clearing or scale. Candidal infection usually involves the scrotum and may have satellite lesions. See the CKS topic on for more information. Erythrasma — typically small, red-brown macules that may coalesce

2018 NICE Clinical Knowledge Summaries

111. Pubic lice

hair, such as moustaches, beards, axillary hair, hair on the chest, abdomen, or back, as well as pubic and perianal hair. The eyebrows and eyelashes can also be affected. The diagnosis is confirmed if visible pubic lice ('crab'-shaped, grey-brown in colour, and about 2 mm in length) or eggs (yellow/white in colour and smaller than a pinhead) are found on examination. Small blue macules (‘maculae cerulae’) or red papules — may be seen at feeding sites. Rust-coloured flecks of faecal material (...) , crusting and matting of eyelashes and conjunctivitis. Visible lice or nits in any area with coarse body hair (most often the pubic area, less commonly the axillae, chest, abdomen, perianal area, beard area, eyelashes and eyebrows). Rust-coloured flecks of faecal material may be seen. Skin lesions such as: Small blue macules (‘maculae cerulae’) or red papules — may be seen at feeding sites. Lichenification and hyperpigmentation of pruritic areas — may occur in chronic infestation. Basis

2018 NICE Clinical Knowledge Summaries

112. Psoriasis

— may mimic flexural psoriasis, but typically presents with bright red papules, pustules, and superficial erosions with satellite lesions. See the CKS topic on for more information. Norwegian scabies — may present with hyperkeratosis similar to that of psoriasis, with genital and axillary fold involvement. See the CKS topic on for more information. Secondary syphilis — consider if there is palmar or plantar involvement with macules, papules, pustules, or plaques, which may mimic localized pustular

2018 NICE Clinical Knowledge Summaries

113. Urticaria

— the early lesions are pruritic and have a similar appearance to an urticarial rash. Polymorphic eruption of pregnancy — urticarial itchy papules mainly occur in the third trimester of pregnancy, often starting on abdominal stretch marks. Urticaria pigmentosa (a form of mastocytosis) — the skin becomes inflamed and red when stroked (Derier's sign) and has hyperpigmented macules and papules. Urticarial vasculitis — lesions remain for longer than 24 hours and are painful, non-blanching, and palpable

2018 NICE Clinical Knowledge Summaries

114. Chickenpox

infection. In immunocompromised people, severe disseminated chickenpox with varicella pneumonia, encephalitis, hepatitis, and haemorrhagic complications. The clinical features of chickenpox include: Prodromal symptoms such as nausea, myalgia, anorexia, headache, general malaise, and loss of appetite. Small, erythematous macules which appear on the scalp, face, trunk, and proximal limbs, and progress over 12–14 hours to papules, clear vesicles (which are intensely itchy), and pustules. Vesicles can also (...) . On examination, look for: Fever. Rash: Small, erythematous macules appear on the scalp, face, trunk, and proximal limbs, which progress over 12–14 hours to papules, clear vesicles (which are intensely itchy), and pustules. Vesicles can also occur on the palms and soles, and mucous membranes can also be affected, with painful and shallow oral or genital ulcers. Vesicles appear in crops; stages of development of the rash can therefore differ on different areas of the body. Crusting occurs usually within 5 days

2018 NICE Clinical Knowledge Summaries

115. Febrile seizure

sclerosis may be suggested by facial angiofibromas, shagreen or leather patches, periungual fibromas, and hypopigmented macules ('ash-leaf spots'). Neurofibromatosis may be suggested by cafe au lait spots, intertriginous freckling, iris hamartomas, and subcutaneous nodules. Basis for recommendation Basis for recommendation The information on the differential diagnosis of febrile seizure is based on the American Academy of Pediatrics (AAP) clinical practice guideline Febrile seizures: guideline

2018 NICE Clinical Knowledge Summaries

116. Scarlet fever

disappears, leaving the tongue with a beefy red appearance. Swollen cervical lymphadenopathy. Flushed face, with marked circumoral pallor. Pharyngitis, and red macules dotted over the hard and soft palate (Forchheimer spots). Be alert for symptoms and signs of scarlet fever in people who are at increased risk of invasive Group A Streptococcal infection (iGAS) including: Those who are immunocompromised. Those with co-morbidities such as diabetes mellitus. Those with co-existing chickenpox or breaks

2018 NICE Clinical Knowledge Summaries

117. Dyschromatosis symmetrica hereditaria and reticulate acropigmentation of Kitamura: An update. (PubMed)

Dyschromatosis symmetrica hereditaria and reticulate acropigmentation of Kitamura: An update. Dyschromatosis symmetrica hereditaria (DSH) and reticulate acropigmentation of Kitamura (RAK) are rare, inherited pigmentary diseases. DSH shows a mixture of pigmented and depigmented macules on the extremities. RAK shows reticulated, slightly depressed pigmented macules on the extremities. The causative gene of DSH was clarified as ADAR1 by positional cloning including linkage analysis and haplotype

2019 Journal of dermatological science

118. Hairy cell leukemia presenting with Ecthyma Gangrenosum- a case report. (PubMed)

Hairy cell leukemia presenting with Ecthyma Gangrenosum- a case report. Ecthyma gangrenosum is a cutaneous infectious usually associated with P. aeruginosa. It usually develops In patients with an underlying immunodeficiency.A 50-year old mentally disabled white male with a history of epilepsy presented with fever and a painless red macule on his right arm which rapidly progressed to a painful ulcer. Blood and lesion cultures revealed P.aeruginosa, confirming our clinical diagnosis of ecthyma

Full Text available with Trip Pro

2019 BMC Infectious Diseases

119. Prurigo successfully treated with duloxetine hydrochloride. (PubMed)

Prurigo successfully treated with duloxetine hydrochloride. Prurigo is a common skin disease characterised by erythematous macules and papules/nodules with severe pruritus. We report here two cases with treatment-resistant prurigo that were successfully treated with duloxetine hydrochloride, a serotonin-norepinephrine reuptake inhibitor. In vivo experiments with a mouse model of prurigo-like inflammation showed that duloxetine hydrochloride ameliorated not only scratching behaviours, but also

2019 Australasian Journal of Dermatology

120. Juvenile ecthyma gangrenosum caused by Pseudomonas aeruginosa revealing an underlying neutropenia: case report and review of the literature. (PubMed)

Juvenile ecthyma gangrenosum caused by Pseudomonas aeruginosa revealing an underlying neutropenia: case report and review of the literature. Ecthyma gangrenosum (EG) is characterized by the occurrence of erythematous, violaceous or haemorrhagic macules and/or vesicles, often evolving into necrotic ulcers, with a central grey-black eschar. It is a rare skin condition, usually occurring in immunocompromised patients suffering from bacterial sepsis caused by Pseudomonas aeruginosa. However

2019 Journal of the European Academy of Dermatology and Venereology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>