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Macule

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41. Cafe-Au-Lait Macule

Cafe-Au-Lait Macule Cafe-Au-Lait Macule Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Cafe-Au-Lait Macule Cafe-Au-Lait Macule Aka (...) : Cafe-Au-Lait Macule , Cafe-Au-Lait Spot , Cafe Au Lait II. Pathophysiology Congenital or develops in early childhood from increased deposition III. Epidemiology Often present at birth Isolated lesions are common (present in up to 10-30% of the population) IV. Symptoms Asymptomatic V. Signs "Coffee with milk" (tan to brown) colored flat Usually located on trunk Size varies from <4 cm in infants to 20-30 cm in adults VI. Red Flags: Criteria to consider associated congenital conditions below Six

2015 FP Notebook

42. Macule

Macule Macule Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Macule Macule Aka: Macule , Patch II. Description Non-palpable flat (...) lesion with change Patches are Macule that are >3-4 cm in diameter III. Signs Macules are flat and not palpable If raised, then consider or Methods to determine if lesion raised Side lighting Careful palpation Color (e.g. ) (e.g. s) Hemosiderin (e.g. s) Vascular changes (e.g. ) IV. Examples Drug Eruption or Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Macule." Click on the image (or right click) to open the source website

2015 FP Notebook

43. Labial Melanotic Macule

Labial Melanotic Macule Labial Melanotic Macule Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Labial Melanotic Macule Labial (...) Melanotic Macule Aka: Labial Melanotic Macule From Related Chapters II. Epidemiology Most common in young women III. Signs Lower lip with brown s IV. Differential Diagnosis darken with and Labial Melanotic Macules do not V. Management Benign Excise only for cosmetic reasons Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Labial Melanotic Macule." Click on the image (or right click) to open the source website in a new browser window

2015 FP Notebook

44. Cutaneous Myeloid Sarcoma Presenting as Grey Pigmented Macules. Full Text available with Trip Pro

Cutaneous Myeloid Sarcoma Presenting as Grey Pigmented Macules. 22278733 2013 03 29 2015 11 19 1651-2057 92 6 2012 Nov Acta dermato-venereologica Acta Derm. Venereol. Cutaneous myeloid sarcoma presenting as grey pigmented macules. 629-30 10.2340/00015555-1312 Niiyama Shiro S Amoh Yasuyuki Y Watarai Akira A Katsuoka Kensei K Mukai Hideki H eng Case Reports Letter Sweden Acta Derm Venereol 0370310 0001-5555 0 Biomarkers, Tumor 04079A1RDZ Cytarabine 74KXF8I502 Aclarubicin 9YVR68W306 enocitabine IM

2012 Acta Dermato-Venereologica

45. JAAD Grand Rounds quiz: Erythematous macules and crusted erosions in sun-exposed areas. (Abstract)

JAAD Grand Rounds quiz: Erythematous macules and crusted erosions in sun-exposed areas. 22507582 2012 06 05 2012 04 17 1097-6787 66 5 2012 May Journal of the American Academy of Dermatology J. Am. Acad. Dermatol. JAAD grand rounds. Erythematous macules and crusted erosions in sun-exposed areas. 862-3 10.1016/j.jaad.2010.10.009 Pfingstler Lisa F LF Adams David R DR eng Case Reports Journal Article United States J Am Acad Dermatol 7907132 0190-9622 0 Anti-Bacterial Agents IM Acne Vulgaris

2012 Journal of American Academy of Dermatology

46. Giant Mongolian Macules with Bilateral Ocular Involvement: Case Report and Review. (Abstract)

Giant Mongolian Macules with Bilateral Ocular Involvement: Case Report and Review. Dermal melanocytosis is characterized by the presence of spindle-shaped melanocytes in the dermis. The most common form is Mongolian spots. A 15-month-old girl from Azerbaijan had a systematized dark blue-gray hyperpigmentation on her shoulder, back and extremities. The hyperpigmentation was also found on both sclera and choroidal areas, without any other facial involvement. On histopathological examination (...) , dense melanocytes were found on the intermediate and deep dermis. Her physical and mental development was normal. This association of blue macules and involvement of both sclerae does not represent a distinct entity and cannot be categorized as an example of nevus of Ota.Copyright © 2012 S. Karger AG, Basel.

2012 Dermatology

47. Labial Melanotic Macule: A Potential Pitfall on Reflectance Confocal Microscopy. Full Text available with Trip Pro

Labial Melanotic Macule: A Potential Pitfall on Reflectance Confocal Microscopy. 22414589 2012 12 07 2012 07 04 1421-9832 224 3 2012 Dermatology (Basel, Switzerland) Dermatology (Basel) Labial melanotic macule: a potential pitfall on reflectance confocal microscopy. 209-11 10.1159/000336775 Erfan N N Hofman V V Desruelles F F Passeron T T Ortonne J P JP Lacour J P JP Bahadoran P P eng Case Reports Letter 2012 03 09 Switzerland Dermatology 9203244 1018-8665 IM Adult Dermoscopy methods Female

2012 Dermatology

48. Purpuric macules with vesiculobullous lesions: a novel manifestation of Chikungunya. (Abstract)

Purpuric macules with vesiculobullous lesions: a novel manifestation of Chikungunya. Chikungunya (CHIK) is an emerging viral disease with a myriad of cutaneous manifestations.The aim of our study was to document the morphology and evolution of skin lesions in cases presenting with fever, purpuric macules and vesiculobullous lesions, to confirm its causative relationship with CHIK, and to investigate further in order to delineate possible mechanisms of bulla formation in these cases.A (...) prospective, descriptive hospital-based study was carried out at a tertiary health care centre in Kerala. A total of 10 patients were enrolled in the study and investigated.All cases had morbilliform eruption prior to onset of purpuric macules. Eight cases developed vesiculobullous lesions that arose either de novo or over a part or whole of the purpuric macules. Skin lesions resolved within an average of 7.6 days leaving post-inflammatory hypopigmentation. IgM CHIK enzyme-linked immunosorbent assay

2011 International Journal of Dermatology

49. Naevus anaemicus-like hypopigmented macules in dyskeratosis congenita. (Abstract)

Naevus anaemicus-like hypopigmented macules in dyskeratosis congenita. In the present paper we report on a Taiwanese case of X-linked recessive dyskeratosis congenita (DC), confirmed by detection of a 214 C→T mutation in the DKC1 gene, and provide a detailed description of mottled pigmentary changes of the skin, specifically numerous small, whitish macules dispersed against a background of diffuse, finely reticulated hyperpigmentation. The hypopigmented macules showed no discernible erythema (...) upon rubbing or the local application of heat. The naevus anaemicus-like macules may be a relatively common but under-recognized feature in DC. More studies are required to determine the incidence and histopathology of these macules.© 2011 The Authors. Australasian Journal of Dermatology © 2011 The Australasian College of Dermatologists.

2011 Australasian Journal of Dermatology

50. Treatment of café au lait macules in Chinese patients with a Q-switched 755-nm alexandrite laser. (Abstract)

Treatment of café au lait macules in Chinese patients with a Q-switched 755-nm alexandrite laser. Café au lait macules (CALMs) are a benign epidermal hyperpigmentation disorder. Although CALMs have been removed successfully with lasers, there have been few investigations on the use of the Q-switched 755-nm alexandrite laser.To evaluate the efficacy and safety of the Q-switched 755-nm alexandrite laser for the treatment of CALMs in Chinese patients.In this retrospective study, data of CALMs

2011 Journal of Dermatological Treatment

51. Nevi

nevus are: high clinical suspicion of melanoma; history of change in the lesion, supported by physical examination; and/or high suspicion of atypical features suggestive of melanoma. Definition Melanocytic nevi are a group of benign neoplasms or hamartomas made up of melanocytes, the pigment-producing cells of the epidermis. They can present in a variety of ways, most commonly as small, brown, flat macules, raised mammillated dome-shaped papules, bluish-grey macules and papules, and even amelanotic (...) skin-coloured papules. Unless congenital, they first appear in childhood and are more common in people with light skin and eyes. McKee PH, Calonje E, Granter SR, eds. Pathology of the skin. 3rd ed. London: Elsevier; 2005. History and exam presence of risk factors presence since birth asymmetrical, indistinct or irregularly bordered, variably coloured papules with diameter >5 mm history of change in shape and colour asymptomatic (usually) multiple lesions flat, brown macule dome-shaped papule light

2019 BMJ Best Practice

52. Assessment of maculopapular rash

Assessment of maculopapular rash Assessment of maculopapular rash - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of maculopapular rash Last reviewed: February 2019 Last updated: February 2019 Summary The patient with an acute maculopapular rash presents a diagnostic challenge to the clinician. The term 'maculopapular is non-specific, as many eruptions have a primary morphology of macules or papules (...) . Morphological terms: Macule: a flat skin lesion ≤1 cm in greatest diameter. When macules are >1 cm, the appropriate term is patch. Papule: a raised bump ≤1 cm in diameter. When papules are >1 cm in size, the appropriate term is plaque (palpable lesions elevated above the skin surface) or nodule (a larger, firm papule with a significant vertical dimension). Other morphological terms encountered in this clinical setting include: Pustule: a papule containing purulent fluid Vesicle: a papule containing clear

2019 BMJ Best Practice

55. Haemangioma

Haemangioma Haemangioma - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Haemangioma Last reviewed: February 2019 Last updated: April 2018 Summary Benign vascular lesions that typically appear during the first weeks of life as blue or pink macules or patches. First-line therapies include topical or systemic beta-blockers (such as timolol and propranolol) and systemic corticosteroids. Adverse effects from prolonged (...) , high-dose oral corticosteroids are common. Definition Infantile haemangiomas, referred to by many simply as 'haemangiomas', are benign vascular lesions. Typically they appear during the first weeks of life as blue or pink macules or patches. They subsequently enter a proliferative phase and become elevated above the surrounding skin surfaces. This growth pattern distinguishes haemangiomas from other vascular lesions. The proliferative growth phase of most haemangiomas is usually completed by age 9

2018 BMJ Best Practice

56. Assessment of rash in children

, ranging from self-limiting conditions (e.g., roseola) to life-threatening illnesses such as meningococcal disease. Several systemic conditions with a serious clinical course may have a rash as a component and should be assessed urgently if suspected (see Urgent considerations). Definitions Macule: a flat area of colour change <1 cm in size (e.g., viral exanthem [such as measles and rubella], morbilliform drug eruption). Patch: a large macule >1 cm in size (e.g., viral exanthem [such as measles

2018 BMJ Best Practice

57. Leprosy

Leprosy Leprosy - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Leprosy Last reviewed: February 2019 Last updated: February 2018 Summary Chronic infectious disease caused by the acid-fast bacteria Mycobacterium leprae , characterised by skin lesion(s) and involvement of peripheral nerves. Skin lesions can be erythematous or hypopigmented, single or multiple macules, papules, or nodules, sometimes with loss

2018 BMJ Best Practice

58. Assessment of maculopapular rash

Assessment of maculopapular rash Assessment of maculopapular rash - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of maculopapular rash Last reviewed: February 2019 Last updated: February 2019 Summary The patient with an acute maculopapular rash presents a diagnostic challenge to the clinician. The term 'maculopapular is non-specific, as many eruptions have a primary morphology of macules or papules (...) . Morphological terms: Macule: a flat skin lesion ≤1 cm in greatest diameter. When macules are >1 cm, the appropriate term is patch. Papule: a raised bump ≤1 cm in diameter. When papules are >1 cm in size, the appropriate term is plaque (palpable lesions elevated above the skin surface) or nodule (a larger, firm papule with a significant vertical dimension). Other morphological terms encountered in this clinical setting include: Pustule: a papule containing purulent fluid Vesicle: a papule containing clear

2018 BMJ Best Practice

59. Roseola

are discrete 3- to 5-mm pink-red macules and papules that commonly begin on the neck and trunk and spread to the extremities. Roseola is usually a benign self-limited illness that has been associated with febrile seizures. Definition Roseola infantum (also called exanthema subitum, sixth disease) is a common early childhood febrile illness, usually characterised by 3 to 5 days of high fever followed by onset of rash that appears with defervescence. The rash consists of asymptomatic pink-red macules

2018 BMJ Best Practice

60. Erythema infectiosum

populations may be at risk for chronic anaemia or transient aplastic crises. Fetal complications include hydrops fetalis and intrauterine fetal demise. History and exam close contact with other infected individuals bright red macular erythema of the bilateral cheeks with sparing of the nasal ridge and peri-oral areas erythematous macules and papules evolving into lacy reticular erythema, most notable on the extremities immunodeficiency arthralgia/arthritis prodrome (fever, headache, pharyngitis, coryza

2018 BMJ Best Practice

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