How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,316 results for

Macule

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

41. Giant Mongolian Macules with Bilateral Ocular Involvement: Case Report and Review. (PubMed)

Giant Mongolian Macules with Bilateral Ocular Involvement: Case Report and Review. Dermal melanocytosis is characterized by the presence of spindle-shaped melanocytes in the dermis. The most common form is Mongolian spots. A 15-month-old girl from Azerbaijan had a systematized dark blue-gray hyperpigmentation on her shoulder, back and extremities. The hyperpigmentation was also found on both sclera and choroidal areas, without any other facial involvement. On histopathological examination (...) , dense melanocytes were found on the intermediate and deep dermis. Her physical and mental development was normal. This association of blue macules and involvement of both sclerae does not represent a distinct entity and cannot be categorized as an example of nevus of Ota.Copyright © 2012 S. Karger AG, Basel.

2012 Dermatology

42. JAAD Grand Rounds quiz: Erythematous macules and crusted erosions in sun-exposed areas. (PubMed)

JAAD Grand Rounds quiz: Erythematous macules and crusted erosions in sun-exposed areas. 22507582 2012 06 05 2012 04 17 1097-6787 66 5 2012 May Journal of the American Academy of Dermatology J. Am. Acad. Dermatol. JAAD grand rounds. Erythematous macules and crusted erosions in sun-exposed areas. 862-3 10.1016/j.jaad.2010.10.009 Pfingstler Lisa F LF Adams David R DR eng Case Reports Journal Article United States J Am Acad Dermatol 7907132 0190-9622 0 Anti-Bacterial Agents IM Acne Vulgaris

2012 Journal of American Academy of Dermatology

43. Cutaneous Myeloid Sarcoma Presenting as Grey Pigmented Macules. (PubMed)

Cutaneous Myeloid Sarcoma Presenting as Grey Pigmented Macules. 22278733 2013 03 29 2015 11 19 1651-2057 92 6 2012 Nov Acta dermato-venereologica Acta Derm. Venereol. Cutaneous myeloid sarcoma presenting as grey pigmented macules. 629-30 10.2340/00015555-1312 Niiyama Shiro S Amoh Yasuyuki Y Watarai Akira A Katsuoka Kensei K Mukai Hideki H eng Case Reports Letter Sweden Acta Derm Venereol 0370310 0001-5555 0 Biomarkers, Tumor 04079A1RDZ Cytarabine 74KXF8I502 Aclarubicin 9YVR68W306 enocitabine IM

Full Text available with Trip Pro

2012 Acta Dermato-Venereologica

44. Labial Melanotic Macule

Labial Melanotic Macule Labial Melanotic Macule Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Labial Melanotic Macule Labial (...) Melanotic Macule Aka: Labial Melanotic Macule From Related Chapters II. Epidemiology Most common in young women III. Signs Lower lip with brown s IV. Differential Diagnosis darken with and Labial Melanotic Macules do not V. Management Benign Excise only for cosmetic reasons Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Labial Melanotic Macule." Click on the image (or right click) to open the source website in a new browser window

2015 FP Notebook

45. Cafe-Au-Lait Macule

Cafe-Au-Lait Macule Cafe-Au-Lait Macule Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Cafe-Au-Lait Macule Cafe-Au-Lait Macule Aka (...) : Cafe-Au-Lait Macule , Cafe-Au-Lait Spot , Cafe Au Lait II. Pathophysiology Congenital or develops in early childhood from increased deposition III. Epidemiology Often present at birth Isolated lesions are common (present in up to 10-30% of the population) IV. Symptoms Asymptomatic V. Signs "Coffee with milk" (tan to brown) colored flat Usually located on trunk Size varies from <4 cm in infants to 20-30 cm in adults VI. Red Flags: Criteria to consider associated congenital conditions below Six

2015 FP Notebook

46. Macule

Macule Macule Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Macule Macule Aka: Macule , Patch II. Description Non-palpable flat (...) lesion with change Patches are Macule that are >3-4 cm in diameter III. Signs Macules are flat and not palpable If raised, then consider or Methods to determine if lesion raised Side lighting Careful palpation Color (e.g. ) (e.g. s) Hemosiderin (e.g. s) Vascular changes (e.g. ) IV. Examples Drug Eruption or Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Macule." Click on the image (or right click) to open the source website

2015 FP Notebook

47. Naevus anaemicus-like hypopigmented macules in dyskeratosis congenita. (PubMed)

Naevus anaemicus-like hypopigmented macules in dyskeratosis congenita. In the present paper we report on a Taiwanese case of X-linked recessive dyskeratosis congenita (DC), confirmed by detection of a 214 C→T mutation in the DKC1 gene, and provide a detailed description of mottled pigmentary changes of the skin, specifically numerous small, whitish macules dispersed against a background of diffuse, finely reticulated hyperpigmentation. The hypopigmented macules showed no discernible erythema (...) upon rubbing or the local application of heat. The naevus anaemicus-like macules may be a relatively common but under-recognized feature in DC. More studies are required to determine the incidence and histopathology of these macules.© 2011 The Authors. Australasian Journal of Dermatology © 2011 The Australasian College of Dermatologists.

2011 Australasian Journal of Dermatology

48. Treatment of café au lait macules in Chinese patients with a Q-switched 755-nm alexandrite laser. (PubMed)

Treatment of café au lait macules in Chinese patients with a Q-switched 755-nm alexandrite laser. Café au lait macules (CALMs) are a benign epidermal hyperpigmentation disorder. Although CALMs have been removed successfully with lasers, there have been few investigations on the use of the Q-switched 755-nm alexandrite laser.To evaluate the efficacy and safety of the Q-switched 755-nm alexandrite laser for the treatment of CALMs in Chinese patients.In this retrospective study, data of CALMs

2011 Journal of Dermatological Treatment

49. Purpuric macules with vesiculobullous lesions: a novel manifestation of Chikungunya. (PubMed)

Purpuric macules with vesiculobullous lesions: a novel manifestation of Chikungunya. Chikungunya (CHIK) is an emerging viral disease with a myriad of cutaneous manifestations.The aim of our study was to document the morphology and evolution of skin lesions in cases presenting with fever, purpuric macules and vesiculobullous lesions, to confirm its causative relationship with CHIK, and to investigate further in order to delineate possible mechanisms of bulla formation in these cases.A (...) prospective, descriptive hospital-based study was carried out at a tertiary health care centre in Kerala. A total of 10 patients were enrolled in the study and investigated.All cases had morbilliform eruption prior to onset of purpuric macules. Eight cases developed vesiculobullous lesions that arose either de novo or over a part or whole of the purpuric macules. Skin lesions resolved within an average of 7.6 days leaving post-inflammatory hypopigmentation. IgM CHIK enzyme-linked immunosorbent assay

2011 International Journal of Dermatology

50. Phenotypic variability among café-au-lait macules in neurofibromatosis type 1. (PubMed)

Phenotypic variability among café-au-lait macules in neurofibromatosis type 1. Café-au-lait macules (CALMs) in neurofibromatosis type 1 (NF1) are an early and accessible phenotype in NF1, but have not been extensively studied.We sought to more fully characterize the phenotype of CALMs in patients with NF1.In all, 24 patients with a diagnosis of NF1 confirmed through clinical diagnosis or molecular genetic testing were recruited from patients seen in the genetics department at the University

Full Text available with Trip Pro

2010 Journal of American Academy of Dermatology

51. The Impact of In Vivo Reflectance Confocal Microscopy on the Diagnostic Accuracy of Lentigo Maligna and Equivocal Pigmented and Nonpigmented Macules of the Face. (PubMed)

The Impact of In Vivo Reflectance Confocal Microscopy on the Diagnostic Accuracy of Lentigo Maligna and Equivocal Pigmented and Nonpigmented Macules of the Face. Limited studies have reported the in vivo reflectance confocal microscopy (RCM) features of lentigo maligna (LM). A total of 64 RCM features were scored retrospectively and blinded to diagnosis in a consecutive series of RCM sampled, clinically equivocal, macules of the face (n=81 LM, n=203 benign macules (BMs)). In addition

Full Text available with Trip Pro

2010 Journal of Investigative Dermatology

52. A Population-Based Study of Acquired Bilateral Nevus-of-Ota-Like Macules in Shanghai, China. (PubMed)

A Population-Based Study of Acquired Bilateral Nevus-of-Ota-Like Macules in Shanghai, China. Acquired bilateral nevus-of-Ota-like macule (ABNOM) is a common skin dyspigmentation in Asian females. Although its clinical characteristics are well defined, its epidemiology and pathogenesis remain unclear. A large population-based cross-sectional study was conducted to determine the prevalence and risk factors of ABNOM. A total of 8,680 subjects (ages ranging from newborn to 99 years old; 54% female

Full Text available with Trip Pro

2010 Journal of Investigative Dermatology

53. Acquired Bilateral Nevus of Ota-like Macules: An Immunohistological Analysis of Dermal Melanogenic Paracrine Cytokine Networks. (PubMed)

Acquired Bilateral Nevus of Ota-like Macules: An Immunohistological Analysis of Dermal Melanogenic Paracrine Cytokine Networks. Acquired bilateral naevus of Ota-like macules (ABNOM) is similar to melasma with regard to their clinical features, including female predominance, acquired onset, and predominant involvement of the malar area. The similar clinical features suggest the possibility of a shared pathogenesis. Dermal factors including vascularity and melanogenic paracrine networks

2010 British Journal of Dermatology

54. Nevi

nevus are: high clinical suspicion of melanoma; history of change in the lesion, supported by physical examination; and/or high suspicion of atypical features suggestive of melanoma. Definition Melanocytic nevi are a group of benign neoplasms or hamartomas made up of melanocytes, the pigment-producing cells of the epidermis. They can present in a variety of ways, most commonly as small, brown, flat macules, raised mammillated dome-shaped papules, bluish-grey macules and papules, and even amelanotic (...) skin-coloured papules. Unless congenital, they first appear in childhood and are more common in people with light skin and eyes. McKee PH, Calonje E, Granter SR, eds. Pathology of the skin. 3rd ed. London: Elsevier; 2005. History and exam presence of risk factors presence since birth asymmetrical, indistinct or irregularly bordered, variably coloured papules with diameter >5 mm history of change in shape and colour asymptomatic (usually) multiple lesions flat, brown macule dome-shaped papule light

2019 BMJ Best Practice

55. Assessment of maculopapular rash

Assessment of maculopapular rash Assessment of maculopapular rash - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of maculopapular rash Last reviewed: February 2019 Last updated: February 2019 Summary The patient with an acute maculopapular rash presents a diagnostic challenge to the clinician. The term 'maculopapular is non-specific, as many eruptions have a primary morphology of macules or papules (...) . Morphological terms: Macule: a flat skin lesion ≤1 cm in greatest diameter. When macules are >1 cm, the appropriate term is patch. Papule: a raised bump ≤1 cm in diameter. When papules are >1 cm in size, the appropriate term is plaque (palpable lesions elevated above the skin surface) or nodule (a larger, firm papule with a significant vertical dimension). Other morphological terms encountered in this clinical setting include: Pustule: a papule containing purulent fluid Vesicle: a papule containing clear

2019 BMJ Best Practice

56. Infantile spasms

identification and treatment of the spasms improves prognosis. History and exam presence of risk factors spasms head nodding neurodevelopmental delay or regression ash leaf macules onset age 3-12 months perinatal complication abnormal eye movements microcephaly motor system abnormalities brain malformation neurocutaneous syndrome antenatal or perinatal vascular event intrauterine or perinatal infections inherited metabolic disorder genetic disorders family history neonatal sinovenous thrombosis postnatal

2018 BMJ Best Practice

57. Overview of skin cancer

or systemic treatment is usually dependent on both doctor and patient preference, as no one treatment option has been shown to be superior to another. Lesions are skin-coloured, yellowish or erythematous, ill-defined, irregularly shaped, small scaly macules or plaques localised in sun-exposed areas of the body (e.g., face, lower lip, dorsum of the hands, forearms, bald areas of the scalp, and ears). [Figure caption and citation for the preceding image starts]: Regular actinic keratosis From the collection

2018 BMJ Best Practice

58. Haemangioma

Haemangioma Haemangioma - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Haemangioma Last reviewed: February 2019 Last updated: April 2018 Summary Benign vascular lesions that typically appear during the first weeks of life as blue or pink macules or patches. First-line therapies include topical or systemic beta-blockers (such as timolol and propranolol) and systemic corticosteroids. Adverse effects from prolonged (...) , high-dose oral corticosteroids are common. Definition Infantile haemangiomas, referred to by many simply as 'haemangiomas', are benign vascular lesions. Typically they appear during the first weeks of life as blue or pink macules or patches. They subsequently enter a proliferative phase and become elevated above the surrounding skin surfaces. This growth pattern distinguishes haemangiomas from other vascular lesions. The proliferative growth phase of most haemangiomas is usually completed by age 9

2018 BMJ Best Practice

59. Assessment of rash in children

, ranging from self-limiting conditions (e.g., roseola) to life-threatening illnesses such as meningococcal disease. Several systemic conditions with a serious clinical course may have a rash as a component and should be assessed urgently if suspected (see Urgent considerations). Definitions Macule: a flat area of colour change <1 cm in size (e.g., viral exanthem [such as measles and rubella], morbilliform drug eruption). Patch: a large macule >1 cm in size (e.g., viral exanthem [such as measles

2018 BMJ Best Practice

60. Assessment of maculopapular rash

Assessment of maculopapular rash Assessment of maculopapular rash - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of maculopapular rash Last reviewed: February 2019 Last updated: February 2019 Summary The patient with an acute maculopapular rash presents a diagnostic challenge to the clinician. The term 'maculopapular is non-specific, as many eruptions have a primary morphology of macules or papules (...) . Morphological terms: Macule: a flat skin lesion ≤1 cm in greatest diameter. When macules are >1 cm, the appropriate term is patch. Papule: a raised bump ≤1 cm in diameter. When papules are >1 cm in size, the appropriate term is plaque (palpable lesions elevated above the skin surface) or nodule (a larger, firm papule with a significant vertical dimension). Other morphological terms encountered in this clinical setting include: Pustule: a papule containing purulent fluid Vesicle: a papule containing clear

2018 BMJ Best Practice

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>