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181. Corkscrew retinal vessels and retinal arterial macroaneurysm in a patient with neurofibromatosis type 1: A case report. (PubMed)

with 2 simultaneous vascular abnormalities, involving tiny spiral venous changes (corkscrew retinal vessels) and retinal arterial macroaneurysms. Our patient was diagnosed with NF-1 as she met the following National Institutes of Health consensus criteria for the diagnosis of NF-1: more than 6 cafe au lait macules, of a maximum diameter ≥15mm, 2 neurofibromas within the dermis, and Lisch nodules on the iris.Retinal arterial macroaneurysm in the left eye, corkscrew retinal vessels related to NF-1

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2018 Medicine

182. A novel approach to the classification of epidermodysplasia verruciformis. (PubMed)

A novel approach to the classification of epidermodysplasia verruciformis. Epidermodysplasia verruciformis (EV) is a rare genodermatosis that causes disseminated eruptions of hypo- or hyperpigmented macules and wart-like papules that can coalesce and scale. It is uniquely characterized by an increased susceptibility to specific human papillomavirus (HPV) genotypes. Classically, EV is associated with mutations of the EVER1/TMC6 and EVER2/TMC8 genes. The term "acquired" epidermodysplasia

2018 International Journal of Dermatology

183. Cutaneous Neonatal Lupus Erythematosus: A Case Report (PubMed)

Cutaneous Neonatal Lupus Erythematosus: A Case Report Cutaneous neonatal lupus erythematosus (NLE) is a rare condition caused by the passive transfer of autoantibodies from mother to fetus. The disease most commonly presents itself with multiple erythematosus annular lesions or arcuate macules. In 10% of the cases, a cardiac anomaly can coexist. Appropriate diagnosis and laboratory and cardiac testing should be done to rule out any complications. Treatment usually includes topical steroids

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2018 Cureus

184. Case Report: “Incognito” proteus syndrome (PubMed)

and a series of subtle clinical signs, such as asymmetric face, scoliosis, multiple lipomas on the trunk, linear verrucous epidermal nevi, and hyperpigmented macules with a mosaic distribution. Even if the clinical presentation was elusive, she had enough criteria to be diagnosed with PS. This case describes the first evidence, to the best of our knowledge, of pauci-symptomatic PS in adulthood, reports its rare association with advanced melanoma, and illustrates the importance of even minor cutaneous

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2018 F1000Research

185. Clinicopathologic findings of guttate leukoderma in Darier disease: A helpful diagnostic feature (PubMed)

of Medicine, Gainesville, Florida. eng Case Reports 2018 03 06 United States JAAD Case Rep 101665210 2352-5126 DD, Darier disease Darier disease GL, guttate leukoderma IGH, idiopathic guttate hypomelanosis guttate leukoderma hypopigmented macules keratosis follicularis 2018 4 25 6 0 2018 4 25 6 0 2018 4 25 6 1 epublish 29687067 10.1016/j.jdcr.2017.09.021 S2352-5126(17)30230-8 PMC5909488 J Eur Acad Dermatol Venereol. 2016 Dec;30(12 ):e205-e209 26853929 J Am Acad Dermatol. 1992 Jul;27(1):40-50 1619075 Am J

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2018 JAAD Case Reports

186. Gigantism in a McCune-Albright’s syndrome with calcified GH-releasing pituitary adenoma: Case report and literature review (PubMed)

Gigantism in a McCune-Albright’s syndrome with calcified GH-releasing pituitary adenoma: Case report and literature review McCune-Albright's syndrome (MAS) is a rare disorder that is characterized by café-au-lait macules, fibrous dysplasia of the skull and endocrinopathies like excessive secretion of growth hormone by a hyper-functional pituitary adenoma (PA).We describe the case of a 43-year-old male with history of Gigantism in 1990 secondary to a GH-secreting pituitary macroadenoma

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2018 International journal of surgery case reports

187. Sclérose tubéreuse de Bourneville: importance de l’anamnèse et de la clinique (PubMed)

and learning difficulties. Epilepsy and brain and renal tumors are treated with aggressive therapeutic and surgical approaches. We report the case of a 13-year old girl, presenting with a 1-year history of acne resistant to therapy. Clinical examination showed symmetric grouped red papules with smooth surface on the central face and the chin (A). The objective clinical examination also showed frontal fibrous plaques (A), achromic macules on the upper limbs and grayish tumors in the periungual folds

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2018 The Pan African medical journal

188. Acquired disorders with depigmentation: A systematic approach to vitiliginoid conditions. (PubMed)

Acquired disorders with depigmentation: A systematic approach to vitiliginoid conditions. Acquired disorders with depigmentation are commonly encountered by dermatologists and present with a wide differential diagnosis. Vitiligo, the most common disorder of acquired depigmentation, is characterized by well-defined depigmented macules and patches. Other conditions, such as chemical leukoderma, can present with similar findings, and are often easily mistaken for vitiligo. Key clinical features

2018 Journal of American Academy of Dermatology

189. The Effect of UVB Phototherapy With Microneedling and Circled Needing in Vitiligo Patients

: October 25, 2018 Last Update Posted : October 26, 2018 See Sponsor: Shin Kong Wu Ho-Su Memorial Hospital Information provided by (Responsible Party): Shin Kong Wu Ho-Su Memorial Hospital Study Details Study Description Go to Brief Summary: Vitiligo is a relatively common acquired disorder of pigmentation characterized by the development of well-defined white macules on the skin. Biopsies of lesional skin reveal a loss of epidermal melanocytes. Lesions may occur in a localized or generalized

2018 Clinical Trials

190. Activation of melanoblasts and melanocytes after treatment with monochromatic excimer light and narrowband-ultraviolet B of skin of vitiligo patients. (PubMed)

Activation of melanoblasts and melanocytes after treatment with monochromatic excimer light and narrowband-ultraviolet B of skin of vitiligo patients. Vitiligo is a hypopigmentation disease characterized by achromatic or hypochromatic macules in several sites of human skin. Although monochromatic excimer light (MEL) and narrowband-ultraviolet B (NB-UVB) have recently been used for efficacious treatment of vitiligo, the repigmentation process and role of melanocytes/melanoblasts are not well (...) known.White macules of 28 vitiligo patients were repeatedly exposed with MEL/NB-UVB. After the exposures, punch biopsies of the center and edge of the lesional skin in addition to normal skin were fixed and processed to dopa and combined dopa-premelanin reactions. Melanocytes positive to the dopa reaction and melanoblasts/melanocytes positive to the combined dopa-premelanin reaction were surveyed.Two repigmentation patterns were observed; one was "marginal" and the other was "perifollicular." Although

2018 International Journal of Dermatology

191. Treatment of Seborrheic Dermatitis: A Comprehensive Review. (PubMed)

Treatment of Seborrheic Dermatitis: A Comprehensive Review. Seborrheic dermatitis (SD) is a chronic, recurring inflammatory skin disorder that manifests as erythematous macules or plaques with varying levels of scaling associated with pruritus. The condition typically occurs as an inflammatory response to Malassezia species and tends to occur on seborrheic areas, such as the scalp, face, chest, back, axilla, and groin areas. SD treatment focuses on clearing signs of the disease; ameliorating

2018 Journal of Dermatological Treatment

192. Interferon alpha as antiviral therapy in chronic active Epstein-Barr virus disease with interstitial pneumonia - case report. (PubMed)

blood, isolated peripheral blood lymphocytes as well as in the blood plasma. Cytokine assessment in peripheral blood revealed the lack of IFN-alpha synthesis. Disseminated maculate infiltrative areas in both lungs were observed on a computed tomography (CT) chest scan. The patient was not qualified for the allogeneic hematopoietic stem cell transplantation (allo-HSCT) due to the risk of immunosuppression-related complications of infectious IP. Inhaled (1.5 million units 3 times a day

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2018 BMC Infectious Diseases

193. The value of 18F-FDG PET/CT in patient with neurofibromatosis type 1: A case report and literature review. (PubMed)

presented with numerous lentigines and multiple café-au-lait macules on his body.These were collagen neurofibroma, which were definitively diagnosed by pathology. NF1 was eventually diagnosed.These lesions were abnormal uptake of radiotracer, when he underwent positron emission tomography (PET) with fluorine-18-fluorodeoxyglucose (FDG) scanning. Standard uptake value (SUV) and other parameters can help to distinguish benign and malignant lesions in patient with NF1. He was underwent serials F-FDG PET/CT

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2018 Medicine

194. The Role of Interleukins in Vitiligo: a Systematic Review. (PubMed)

The Role of Interleukins in Vitiligo: a Systematic Review. Vitiligo is a disorder of the skin that causes depigmentation and asymptomatic macules whose exact cause is still unclear. Although its aetiology is not fully elucidated, the main theory of its pathomechanism is that it is associated with the autoimmune process. There is few summarized information about the role of inflammatory mediators, as interleukins, in vitiligo, so our aim was to present a systematic review of the role

2018 Journal of the European Academy of Dermatology and Venereology

195. Oral lichen sclerosus: an overview and report of three cases. (PubMed)

lichen sclerosus should be included in the differential diagnosis of porcelain- or ivory-white macules. Here we present three new cases of oral lichen sclerosus. A review of these cases and the previously reported cases revealed that oral lichen sclerosus is slightly more common in women and can affect individuals of any age. Oral lesions of lichen sclerosus usually do not require treatment, except when there are significant symptoms or aesthetic complaint. Almost 50% of the patients with oral lichen

2018 International Journal of Oral and Maxillofacial Surgery

196. Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version

of life and were necrotic papules or hypopigmented macules. Patients with nonregressing disease who required systemic therapy were more often intertriginous. Immunohistochemical studies showed no difference in interleukin (IL)-10, Ki-67, E-cadherin expression, or T-reg number between the two clinical groups. Children and adults: Children and adults may develop a red papular rash in the groin, abdomen, back, or chest that resembles a diffuse candidal rash. Seborrheic involvement of the scalp may

2016 PDQ - NCI's Comprehensive Cancer Database

200. Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version

of life and were necrotic papules or hypopigmented macules. Patients with nonregressing disease who required systemic therapy were more often intertriginous. Immunohistochemical studies showed no difference in interleukin (IL)-10, Ki-67, E-cadherin expression, or T-reg number between the two clinical groups. Children and adults: Children and adults may develop a red papular rash in the groin, abdomen, back, or chest that resembles a diffuse candidal rash. Seborrheic involvement of the scalp may

2016 PDQ - NCI's Comprehensive Cancer Database

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