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Lymphoid Hyperplasia

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981. Nasopharyngeal lymphoid hyperplasia after therapy for childhood lymphomas. Full Text available with Trip Pro

Nasopharyngeal lymphoid hyperplasia after therapy for childhood lymphomas. Although diffuse thymic hyperplasia after therapy has been reported in lymphomas, no report is found in the medical literature about hyperplasia of other lymphoid tissues following chemotherapy in malignancies as far as we could reach. So, we planned to investigate the nasopharyngeal region of the lymphoma cases during their follow-up while at remission. Children who were in follow-up after cessation of oncological (...) therapy with the diagnosis of lymphoma were evaluated for their nasopharyngeal lymphoid tissues by means of computed tomography. When a mass lesion was diagnosed, biopsies were taken. Among 23 lymphoma cases in follow-up, at a median of eight months (range 1-13 months), eight patients (six Hodgkin's and two Non-Hodgkin's malignant lymphoma) developed nasopharyngeal lymphoid hyperplasia (34.78%) that were proven to be benign by means of biopsies. Two of the patients also developed thymic hyperplasia

2006 Acta Oncologica

982. Cutaneous lymphoid hyperplasia and marginal zone B-cell lymphoma following vaccination. (Abstract)

Cutaneous lymphoid hyperplasia and marginal zone B-cell lymphoma following vaccination. Atypical lymphoid infiltrations arose within the influenza inoculation sites of two adult female patients. One patient developed a low-grade cutaneous marginal zone B-cell lymphoma (MZL) that was responsive to local excision and radiation therapy despite spread to a distant cutaneous site. The second patient's clinical course was characterized by a locally aggressive, histologically reactive inflammatory

2005 Journal of American Academy of Dermatology

983. Cutaneous lymphoid hyperplasia presenting as a solitary facial nodule: clinical, histopathological, immunophenotypical, and molecular studies. Full Text available with Trip Pro

Cutaneous lymphoid hyperplasia presenting as a solitary facial nodule: clinical, histopathological, immunophenotypical, and molecular studies. To elucidate the clinicopathological, immunophenotypical, and molecular characteristics of cutaneous lymphoid hyperplasia presenting as a solitary facial nodule.Retrospective study.University dermatology department.Three patients with a solitary facial nodule were studied clinically, histologically, immunophenotypically, and molecularly for T-cell (...) years.Cutaneous lymphoid hyperplasia that presents as a solitary facial nodule may share clinical, cytological, immunophenotypical, and molecular features with both benign reactive lymphocytic infiltrates and cutaneous lymphomas, and therefore a careful clinical and therapeutic approach is warranted.

2006 Archives of Dermatology

984. Lymphomatoid keratosis: an epidermotropic type of cutaneous lymphoid hyperplasia: clinicopathological, immunohistochemical, and molecular biological study of 6 cases. Full Text available with Trip Pro

Lymphomatoid keratosis: an epidermotropic type of cutaneous lymphoid hyperplasia: clinicopathological, immunohistochemical, and molecular biological study of 6 cases. To provide evidence that lymphomatoid keratosis should be categorized as an epidermotropic subtype of cutaneous lymphoid hyperplasia.Clinicopathological, immunohistochemical, and molecular biological studies of epidermotropic and dermal bandlike infiltrates of lymphocytes without necrotic keratinocytes, Civatte bodies, or Max (...) demonstrated in 2 cases and of the TCRbeta gene in 1 case.Our results indicate that lymphomatoid keratosis is a clinically benign keratotic lesion but histologically malignant, simulating mycosis fungoides. Immunohistochemical findings showed a reaction pattern in all cases, but genotypical examination showed some clonal dermatoses. Therefore, "lymphomatoid" keratosis should be classed as a pseudolymphoma, namely, a subtype of cutaneous lymphoid hyperplasia with epidermotropism.

2007 Archives of Dermatology

985. Nodular lymphoid hyperplasia of the lung: a very rare disease entity. (Abstract)

Nodular lymphoid hyperplasia of the lung: a very rare disease entity. Nodular lymphoid hyperplasia of the lung is an uncommon disease that is considered to be a benign lesion of a polyclonal lymphoid proliferation. Because of its rarity, little is known about the clinicopathologic characteristics of nodular lymphoid hyperplasia. Some researchers have questioned whether nodular lymphoid hyperplasias are truly reactive or are marginal zone B-cell lymphomas (low-grade lymphomas of mucosa (...) -associated lymphoid tissue) mimicking reactive lymphoid processes. We present the case of a 67-year-old woman with nodular lymphoid hyperplasia of the lung and discuss the current knowledge concerning nodular lymphoid hyperplasias.

2007 Annals of Thoracic Surgery

986. Lymphoid nodular hyperplasia and cow's milk hypersensitivity in children with chronic constipation. (Abstract)

Lymphoid nodular hyperplasia and cow's milk hypersensitivity in children with chronic constipation. To investigate the incidence of cow's milk allergy as evidenced by milk challenge and the findings of endoscopic and immunohistochemical examinations in children with chronic and refractory constipation.Thirty-five study subjects (mean age, 8.3 +/- 3.3 years; range, 3-15 years; 17 girls) and 15 control subjects (mean age, 11.7 +/- 3.2 years; range, 2-15 years; 9 girls) were studied by colonoscopy (...) and a 4-week cow's milk elimination and challenge.Lymphoid nodular hyperplasia was the most prominent endoscopic finding in half of the subjects (46%), mostly occurring patchily in the transverse colon. Histologic findings other than lymphoid accumulation and mildly increased density of eosinophils were few. During the milk elimination and with supportive medication, 83% of subjects remitted. Constipation and/or other gastrointestinal or skin symptoms relapsed only in one third (34%) during the cow's

2004 Journal of Pediatrics

987. The maedi-visna virus Tat protein induces multiorgan lymphoid hyperplasia in transgenic mice. Full Text available with Trip Pro

The maedi-visna virus Tat protein induces multiorgan lymphoid hyperplasia in transgenic mice. Sheep infected with maedi-visna virus experience immunological disorders leading to progressive chronic diseases involving the brain, lung, spleen, and lymph nodes. To study the biological activity of the viral transactivating Tat protein, we generated transgenic mice carrying the tat gene. Analysis of the transgenic mouse tissues for tat mRNA revealed that while low at the messenger level

1994 Journal of virology

988. Angiofollicular lymphoid hyperplasia in a pulmonary fissure. Full Text available with Trip Pro

Angiofollicular lymphoid hyperplasia in a pulmonary fissure. 4060111 1985 11 29 2018 11 13 0040-6376 40 9 1985 Sep Thorax Thorax Angiofollicular lymphoid hyperplasia in a pulmonary fissure. 686-7 Mohamedani A A AA Bennett M K MK eng Case Reports Journal Article England Thorax 0417353 0040-6376 IM Adult Female Humans Hyperplasia Lung Diseases immunology pathology Lymph Nodes pathology Lymphocytes classification 1985 9 1 1985 9 1 0 1 1985 9 1 0 0 ppublish 4060111 PMC460172 Cancer. 1970 Jun;25(6

1985 Thorax

989. Orbital lymphoma versus reactive lymphoid hyperplasia: an analysis of the use of computed tomography in differential diagnosis. Full Text available with Trip Pro

Orbital lymphoma versus reactive lymphoid hyperplasia: an analysis of the use of computed tomography in differential diagnosis. Computed x ray tomography (CT) studies of 40 patients with proptosis or periorbital swelling, in whom biopsy showed lymphoma in 23 and reactive lymphoid hyperplasia in 17, were analysed in an attempt to identify radiological differences between the two conditions. The results indicate that homogeneity of an orbital mass is a sensitive but non-specific indication

1991 The British journal of ophthalmology

990. Small intestinal nodular lymphoid hyperplasia in patients with giardiasis and normal serum immunoglobulins. Full Text available with Trip Pro

Small intestinal nodular lymphoid hyperplasia in patients with giardiasis and normal serum immunoglobulins. Nodular lymphoid hyperplasia of the upper small intestine was demonstrated in 25 patients with giardiasis. All had normal serum immunoglobulin levels and seven patients initially presented with clinical findings suggestive of an abdominal lymphoma. In only two, however, was the diagnosis of primary jejunal lymphoma confirmed. It is possible that an aetiological relationship exists between (...) recurrent parasitic infestation and nodular lymphoid hyperplasia of the upper small intestine.

1983 Gut

991. Lymphoid hyperplasia in transgenic mice over-expressing a secreted form of the human interleukin-1β gene product Full Text available with Trip Pro

Lymphoid hyperplasia in transgenic mice over-expressing a secreted form of the human interleukin-1β gene product To evaluate the biological effects of over-expression of interleukin-1beta (IL-1beta) on the immune system we have generated transgenic mice, expressing the IL-1beta gene fused to a heterologous signal sequence under the control of the mouse immunoglobulin enhancer (Emu). A prominent hyperplasia and a disturbed microarchitecture of lymphoid tissues were observed in the transgenic (...) mice. The CD4+ T cells in the hyperplastic lymphoid organs seemed to invade the majority of the lymphoid organs including B-cell restricted areas. Analysis of lymph node cells revealed an increased frequency of CD4+ CD44high CD62L- T cells and local secretion of IL-2 and IL-4, compatible with an elevated number of activated T cells. Furthermore, significant levels of human IL-1beta in sera and high concentrations of serum immunoglobulin G (IgG) were observed in the transgenic mice. The data suggest

1999 Immunology

992. Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia. Full Text available with Trip Pro

Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia. To assess the diagnostic accuracy of lymph node fine needle aspiration (FNA) cytology to distinguish reactive lymphoid hyperplasia from malignant lymphoma, and to evaluate the contribution of ancillary techniques applied to cytological material.Two hundred and seventy seven consecutive lymph node FNA specimens reported to be consistent with reactive lymphoid hyperplasia (n = 213) or suggestive (...) aspirates including three cases of follicular lymphoma, two cases of Hodgkin's disease, and one chronic lymphocytic leukaemia. Two FNA specimens considered suspicious of lymphoma proved reactive on histology or clinical follow up. One metastatic small cell carcinoma was wrongly diagnosed as lymphoma. Ancillary studies contributed to the correct diagnosis in most cases although occasional misleading results were obtained, particularly with PCR.FNA cytology accurately distinguished reactive lymphoid

1998 Journal of Clinical Pathology

993. Helicobacter pylori associated gastric diseases and lymphoid tissue hyperplasia in gastric antral mucosa Full Text available with Trip Pro

Helicobacter pylori associated gastric diseases and lymphoid tissue hyperplasia in gastric antral mucosa To investigate the relation between Helicobacter pylori associated gastroduodenal diseases and lymphoid tissue hyperplasia in the antral mucosa and to pursue its evolution after eradication of H pylori.Gastric antral biopsy specimens were obtained from 438 patients with H pylori positive gastroduodenal diseases (185 chronic gastritis, 69 gastric ulcer, and 184 duodenal ulcer) and 50 H pylori (...) negative healthy controls. Lymphoid follicles and aggregates were counted and other pathological features were scored according to the updated Sydney system for classification of chronic gastritis. After a course of anti-H pylori treatment, biopsy specimens were obtained at four to six weeks, 12 months, and 24 months in the chronic gastritis patient group.The total prevalence of lymphoid follicles and aggregates in the biopsies was 79.9% (350 of 438; 95% confidence intervals (CI), 0.76 to 0.84

2002 Journal of Clinical Pathology

994. Focal lymphoid aggregates (nodules) in bone marrow biopsies: differentiation between benign hyperplasia and malignant lymphoma--a practical guideline. Full Text available with Trip Pro

Focal lymphoid aggregates (nodules) in bone marrow biopsies: differentiation between benign hyperplasia and malignant lymphoma--a practical guideline. To provide practical guidelines for the differentiation between benign and malignant focal lymphoid aggregates (lymphoid nodules) in routinely referred bone marrow trephine biopsies, using a synoptic approach including clinical data and histological workup.For easy identification of very small lymphoid infiltrates the chloroacetate esterase stain (...) with corresponding lymph node findings was made.352 patients had benign focal lymphoid aggregates usually associated with systemic autoimmune diseases, chronic myeloproliferative disorders, toxic myelopathy, and viral infections. Discrete nodular infiltrates of (small cell) malignant lymphomas (n = 93) simulating benign hyperplasia were found in chronic lymphocytic leukaemia, germinal centre cell lymphomas (CB-CC), and lymphoplasmacytic/cytoid lymphomas (LPI). In addition to immunoreactivity, certain

1999 Journal of Clinical Pathology

995. Medical treatment of recurrent intussusception associated with intestinal lymphoid hyperplasia. (Abstract)

Medical treatment of recurrent intussusception associated with intestinal lymphoid hyperplasia. Intestinal lymphoid hyperplasia (ILH) is an uncommon cause of recurrent intussusception in infants and young children. Surgical treatment has been suggested in the management of this disorder. We report 2 cases in which recurrent intussusception was associated with ILH. A short course of steroids resulted in resolution of both symptoms and hyperplasia. We conclude that when recurrent intussusception

2003 Pediatrics

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