How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,002 results for

Lymphoid Hyperplasia

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

861. Cutaneous manifestations as presenting sign of autoimmune lymphoproliferative syndrome in childhood. (Abstract)

Cutaneous manifestations as presenting sign of autoimmune lymphoproliferative syndrome in childhood. Autoimmune lymphoproliferative syndrome is a disorder due to a defect of lymphocyte apoptosis, whose clinical manifestations consist of hyperplasia of lymphoid tissues and autoimmune diseases. We report on a 26-month-old child who presented with frequent eruptions of weals and angioedema without any apparent triggering factor, who subsequently developed an erythematopapular rash (...) with a personal and familial history of hyperplasia of lymphoid tissues may be a presenting sign of a systemic disease, such as autoimmune lymphoproliferative syndrome.2005 S. Karger AG, Basel

2005 Dermatology

862. Clinical and pathological features of posttransplantation lymphoproliferative disorders presenting with skin involvement in 4 patients. Full Text available with Trip Pro

Clinical and pathological features of posttransplantation lymphoproliferative disorders presenting with skin involvement in 4 patients. Posttransplantation lymphoproliferative disorders (PTLDs) are lymphoid proliferations that can develop in recipients of solid organ or allogeneic bone marrow transplants. They are clinically and pathologically heterogeneous and range from polyclonal hyperplastic lesions to malignant lymphomas. Although extranodal involvement in PTLD is common, cutaneous (...) hyperplasia to monomorphic PTLD. In situ hybridization detected Epstein-Barr virus messenger RNA in all 3 cases with evaluable tissue. All patients underwent reduction in immunosuppressive therapy and received other individualized treatments. Median follow-up was 2.5 years. At the most recent follow-up, 3 patients were in complete remission and 1 had residual disease.In this study, PTLD lesions presenting in the skin responded to therapy. Despite their relatively late occurrence after transplantation

2004 Archives of Dermatology

863. Morphologic and quantitative assessment of CD20+ B cell infiltrates in rheumatoid arthritis-associated nonspecific interstitial pneumonia and usual interstitial pneumonia. (Abstract)

interstitial pneumonia (IP) in comparison with idiopathic IP and normal lungs.Open-lung biopsy specimens from patients with RA-associated IP (n = 18), patients with idiopathic IP (n = 21), and control subjects (n = 11) were stained with antibodies to CD20 and CD138. Morphologic patterns of stained specimens were characterized and staining was quantified using computer-assisted image analysis.In RA-associated IP, marked follicular B cell hyperplasia was detected, which was limited almost entirely (...) to peribronchiolar lymphoid aggregates. Plasma cells were also present in large numbers, but showed a more diffuse tissue infiltration. Quantification of B cells demonstrated higher cellularity in RA-associated IP (median 2.0%, interquartile range [IQR] 1.0-5.7) as compared with idiopathic IP (0.9%, IQR 0.5-2.1). Control specimens showed a significantly smaller number of B cells compared with both diseases (0.4%, IQR 0.1-1.3). In RA patients who were smokers and in those who were male, the proportion of CD20

2006 Arthritis and Rheumatism

864. Immunomodulatory effects of etanercept on peripheral joint synovitis in the spondylarthropathies. (Abstract)

clinical improvement of peripheral joint disease. Histologic synovitis was down-regulated, with a profound reduction in global cellular infiltration and T lymphocytes, but not B lymphocytes. The most prominent change in markers of inflammation was a reduction in the different macrophage subsets (CD68, CD163, MRP-8, and MRP-14), but this was not paralleled by a decrease in serum MRP-8/MRP-14. Structural changes included normalization of lining layer hyperplasia and a moderate reduction in vascularity (...) . However, no effect on the microarchitecture of lymphoid aggregates was observed. In terms of an effect on matrix degradation, the synovial expression of MMP-3 and MMP-9 was down-modulated in correlation with a rapid and profound decrease in serum MMP-3. At week 52, serum COMP levels were also reduced. No significant radiologic disease progression was observed in these patients over a 2-year period.Use of etanercept effectively down-modulated the immunopathologic processes of SpA synovitis, both

2005 Arthritis and Rheumatism

865. Pitfalls in lymph node staging with positron emission tomography in non-small cell lung cancer patients. (Abstract)

-positive PET scan were: (1) inflammatory conditions in seven patients; (2) PET mis-localization of an interlobar LN as a mediastinal LN in one patient; (3) inability to distinguish the endobronchial polypoid growth of a primary tumor from a lobar LN in one patient; (4) unknown in one patient. All false-positive LNs due to inflammatory conditions showed reactive lymphoid hyperplasia histologically. The causative factors for false-negative PET scan were: (1) limitation of spatial resolution of the PET

2005 Lung Cancer

866. A kindred of children with interstitial lung disease. (Abstract)

a spectrum of pulmonary lymphoid proliferations ranging from reactive lymphoid hyperplasia to lymphoid interstitial pneumonia.The findings of ILD and autoimmunity in a kindred of children suggest a novel genetic disorder of autosomal dominant pattern and variable penetrance. Although the precise pathogenesis remains unclear, these cases provide valuable insight into childhood ILD.

2007 Chest

867. Endotracheal castleman disease: A case report. (Abstract)

Endotracheal castleman disease: A case report. Castleman disease (CD) is an uncommon benign lymphoid hyperplasia with several clinical and morphologic variants associated with distinct outcomes. Pulmonary CD has been reported as a rare extranodal manifestation in the literature. However, CD presenting as an obstructive mass in the airway has not been documented. We report a case of localized hyaline-vascular CD presenting as an endotracheal lesion. The patient was a 50-year-old woman

2007 Chest

868. Neonatal transient eosinophilic colitis causes lower gastrointestinal bleeding in early infancy. (Abstract)

, but they had gross eosinophilia: the eosinophil counts were 9014/mm3 (patient 1) and 1955/mm3 (patient 2). Rectosigmoidoscopy with colonic mucosal biopsy revealed nodular lymphoid hyperplasia with a pale mucosal surface and massive oozing with diffuse eosinophilic infiltration in the lamina propria. In patient 2 the serum ECP and PAF levels were elevated to 123 microg/L (normal, <14.7) and 13.1 micromol/L/min (normal, <6). A few days after intravenous hydration therapy, LGB was no longer detected

2007 Journal of Pediatric Gastroenterology and Nutrition

869. CD154+ graft antigen-specific CD4+ T cells are sufficient for chronic rejection of minor antigen incompatible heart grafts. (Abstract)

the classical vascular changes of chronic rejection. They are capable of doing so without contributions from other lymphocytes, and may cause intimal hyperplasia by using CD154 to stimulate other non-lymphoid cells in the intima. (...) CD154+ graft antigen-specific CD4+ T cells are sufficient for chronic rejection of minor antigen incompatible heart grafts. We used a defined model system to address the role of minor histocompatibility antigen-specific CD4+ T cells in chronic rejection. The coronary arteries of vascularized heart grafts expressing the model antigen ovalbumin developed intimal hyperplasia in normal recipients and those lacking CD8+ T cells but not in those lacking CD4+ T cells. Furthermore, purified ovalbumin

2006 American Journal of Transplantation

870. Synovial inflammation does not change in the absence of effective treatment: implications for the use of synovial histopathology as biomarker in early phase clinical trials in rheumatoid arthritis. Full Text available with Trip Pro

analysed by histology and immunohistochemistry.Over the course of 14 weeks, there was a trend towards a decrease of the DAS28, with 7/12 patients being good or moderate DAS28 responders despite the absence of effective treatment. Patients' assessment of global disease activity and swollen joint count both decreased significantly. Histologically, there was a decrease of lining layer hyperplasia and lymphoid aggregates, a similar trend for vascularity, but there was no effect on global synovial

2006 Annals of the Rheumatic Diseases

871. A novel form of non-X-linked hyperigm associated with growth and pubertal disturbances and with lymphoma development. (Abstract)

A novel form of non-X-linked hyperigm associated with growth and pubertal disturbances and with lymphoma development. HyperIgM syndrome is a heterogenous immunodeficiency characterized by impaired class-switch recombination due to different molecular abnormalities. We report on two female patients affected by a novel syndrome associating HIGM, growth and pubertal disturbances, and severe lymphoid hyperplasia with eventual development into lymphomas, suggesting a DNA repair defect.

2006 Journal of Pediatrics

872. Limited parotidectomy: the role of extracapsular dissection in parotid gland neoplasms. (Abstract)

4.0 to 1.0 cm (mean 2.4 cm) in diameter. Pathology of the parotid tumors consisted of 11 pleomorphic adenomas, six Warthin's tumors, six benign epithelial cysts, one sarcoid lesion, two lymphoid hyperplasia, and one Kaposi's sarcoma. There were no cases of capsular rupture. There was no temporary or permanent facial paralysis and no incidence of Frey's syndrome. One patient developed a sialocele, which was aspirated and resolved after 3 months. There were no recurrences with follow-up times

2007 Laryngoscope

873. Routine nasopharyngeal biopsy in adults presenting with isolated serous otitis media: is it justified? (Abstract)

nasopharyngeal masses were noted to have irregular or exophytic mucosa on flexible nasendoscopy. All patients underwent a EUA of the ears and a nasopharyngeal biopsy. The four patients with suspicious-looking masses were all found to have malignancies (two squamous cell carcinomas, one B-cell non-Hodgkin lymphoma and one adenocarcinoma). Three of these patients presented with unilateral SOM and one with bilateral SOM. All other patients with masses were found to have benign lymphoid hyperplasia. In total

2006 Journal of Laryngology & Otology

874. Primary Antibody Deficiency

). Meningitis and/or sepsis. Gastrointestinal infections (chronic diarrhoea or malabsorption). Cutaneous infections. Autoimmune disorders including autoimmune haemolytic anaemia, neutropenia or thrombocytopenia as well as systemic lupus erythematosus (SLE) and rheumatoid arthritis. Allergic disorders with elevated serum IgE levels. Abnormal lymphoid tissue, such as nodular lymphoid hyperplasia in the gut or congenital absence of tonsils. Unexplained signs such as hepatosplenomegaly or arthropathy (...) to take account of the possibility of unusual infections - eg, giardial enteritis and mycoplasma or ureaplasma arthritis. Complications Complications of PAD include acute infections, which may be due to unusual organisms such as Mycoplasma spp. and long-term complications: [ , ] A number of chronic complications have been described, including: Chest: bronchiectasis, fungal infections, polyclonal lymphoid aggregates, granulomas, lymphoma. Sinuses: recurrent sinusitis. Bowel: infections (giardiasis

2008 Mentor

875. Coping with Uncertainty in Primary Care

in practice: the contribution of decision aids. BMJ 2003327:736-740 [full text] ; A systematic review on communicating with patients about evidence. J Eval Clin Pract. 2006 Feb12(1):13-23. ; Screening for prostate cancer: opportunities and challenges. Surg Oncol Clin N Am. 2005 Oct14(4):747-60. ; Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet. 1998 Feb 28351(9103):637-41. ; A population-based study of measles, mumps, and rubella

2008 Mentor

876. Conjunctival Problems

on the upper tarsal conjunctiva, they can coalesce to form giant (cobblestone) papillae. Follicles - are more often associated with viral conjunctivitis. They are lymphoid collections and are raised gelatinous pale bumps (resembling small grains of rice). They tend to occur on the lower tarsal conjunctiva and along the upper tarsal border. Oedema (chemosis) - translucent swelling of the conjunctiva, suggesting severe inflammation. This commonly occurs immediately after and, in this context (...) melanosis : this consists of multiple slate-grey lesions occurring in the episclera, caused by melanocytic hyperplasia. This may be a precursor to melanoma formation and therefore these patients are monitored in the eye clinic. Conjunctival naevus : this is a relatively uncommon but benign pigmented lesion most commonly occurring adjacent to the limbus in the first two decades of life. If it causes irritation or if there is suspicion of malignant change, it should be excised. Primary acquired melanosis

2008 Mentor

877. Hyperthyroidism (Thyrotoxicosis)

firm on palpation. Some patients have pretibial myxoedema called thyroid dermopathy (as can occur anywhere, particularly following trauma). This is usually associated with moderate-to-severe ophthalmopathy. 10-20% have clubbing (thyroid acropathy). There may also be lymphoid hyperplasia including splenomegaly and an enlarged thymus. The pathophysiology of Graves' disease can have a variable effect on thyroid function and patients may remain euthyroid or become hypothyroid. There may be a personal (...) and hypothermia. [ ] Causes of thyrotoxicosis Graves' disease This is the most common cause of hyperthyroidism and has an autoimmune basis. It is an autoimmune disease mediated by antibodies that stimulate the TSH receptor, leading to excess secretion of thyroid hormones and hyperplasia of thyroid follicular cells, resulting in hyperthyroidism and diffuse goitre. - exophthalmos, ophthalmoplegia, conjunctival oedema, papilloedema and keratopathy. Diffuse moderate enlargement of the thyroid gland which feels

2008 Mentor

878. Graves' Disease

firm on palpation. Some patients have pretibial myxoedema called thyroid dermopathy (as can occur anywhere, particularly following trauma). This is usually associated with moderate-to-severe ophthalmopathy. 10-20% have clubbing (thyroid acropathy). There may also be lymphoid hyperplasia including splenomegaly and an enlarged thymus. The pathophysiology of Graves' disease can have a variable effect on thyroid function and patients may remain euthyroid or become hypothyroid. There may be a personal (...) and hypothermia. [ ] Causes of thyrotoxicosis Graves' disease This is the most common cause of hyperthyroidism and has an autoimmune basis. It is an autoimmune disease mediated by antibodies that stimulate the TSH receptor, leading to excess secretion of thyroid hormones and hyperplasia of thyroid follicular cells, resulting in hyperthyroidism and diffuse goitre. - exophthalmos, ophthalmoplegia, conjunctival oedema, papilloedema and keratopathy. Diffuse moderate enlargement of the thyroid gland which feels

2008 Mentor

879. Hashimoto's Disease

findings in combination with histological appearance. The thyroid gland shows diffuse lymphocytic and plasma cell infiltration with formation of lymphoid follicles from follicular hyperplasia and damage to the follicular basement membrane. Atrophy of the thyroid parenchyma is usually evident. Thyroid autoantibodies may also be seen. TSH levels; this is a sensitive test of thyroid function. [ ] Levels are usually raised in hypothyroidism due to Hashimoto's thyroiditis (but also in primary hypothyroidism

2008 Mentor

880. Linitis plastica

shows a thickening of the submucosal layer of the tumoral wall (up to 10 to 20 mm). CT scan and endoscopic ultrasound may be useful for the diagnosis and for evaluation of local extension. Differential diagnosis The differential diagnosis should include malignant diseases (adenocarcinoma and lymphoma) and some benign diseases with thickening of the gastric wall (Menetrier's disease, lymphoid hyperplasia and amyloidosis; see these terms). Management and treatment Treatment options include surgical

2002 Orphanet

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>