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Lymphoid Hyperplasia

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1. Atypical lymphoid hyperplasia in a patient undergoing tonsillectomy for severe obstructive sleep apnea. (Abstract)

Atypical lymphoid hyperplasia in a patient undergoing tonsillectomy for severe obstructive sleep apnea. Tonsillectomy is a common procedure in the pediatric population, with subsequent microscopic examination of the specimen for cancer and other rare diagnoses occurring routinely. A 17 year-old female with a history of autoimmune vasculitis underwent adenotonsillectomy for severe obstructive sleep apnea. Pathology demonstrated small, medium and large lymphocytes and plasma cells obscuring (...) the lymphoid follicles and germinal centers, with few Epstein-Barr virus positive lymphocytes. Tingible body macrophages were seen in the vaguely nodular areas. This reactive histologic pattern represents an atypical lymphoproliferative disorder never before documented in tonsils. Histopathologic images will be shown.Copyright © 2020. Published by Elsevier B.V.

2020 International Journal of Pediatric Otorhinolaryngology

2. Reactive lymphoid hyperplasia of the liver: A case report. Full Text available with Trip Pro

Reactive lymphoid hyperplasia of the liver: A case report. Reactive lymphoid hyperplasia (RLH) of the liver is an uncommon benign lesion. It is usually difficult to differentiate from hepatocellular carcinoma (HCC), peripheral-type cholangiocellular carcinoma (CCC), combined HCC-CCC, and liver metastases. On account of its rarity and controversial issues, we report a case report and review the literature to discuss its clinical features, treatments, radiological, and immunohistochemical

2019 Medicine

3. Pulmonary Nodular Lymphoid Hyperplasia with Mass-Formation: Clinicopathologic Characteristics of Nine Cases and Review of the Literature Full Text available with Trip Pro

Pulmonary Nodular Lymphoid Hyperplasia with Mass-Formation: Clinicopathologic Characteristics of Nine Cases and Review of the Literature Pulmonary nodular lymphoid hyperplasia (PNLH) is a non-neoplastic pulmonary lymphoid disorder that can be mistaken for malignancy on radiography. Herein, we present nine cases of PNLH, emphasizing clinicoradiological findings and histological features.We analyzed radiological and clinicopathological features from the electronic medical records of nine patients (...) with the disease following treatment for pneumonia. Imaging studies revealed consolidation or a mass-like lesion in eight patients. First impressions included invasive adenocarcinoma and mucosal-associated lymphoid tissue‒type lymphoma. Aspergillosis was suspected in the remaining patient based on radiological images. Resection was performed in all patients. Microscopically, the lesions consisted of nodular proliferation of reactive germinal centers accompanied by infiltration of neutrophils and macrophages

2018 Journal of Pathology and Translational Medicine

4. Sustained remission of recalcitrant cutaneous lymphoid hyperplasia after thalidomide treatment Full Text available with Trip Pro

Sustained remission of recalcitrant cutaneous lymphoid hyperplasia after thalidomide treatment 29687061 2019 02 26 2352-5126 4 3 2018 Apr JAAD case reports JAAD Case Rep Sustained remission of recalcitrant cutaneous lymphoid hyperplasia after thalidomide treatment. 245-247 10.1016/j.jdcr.2018.01.012 Erickson Stephen P SP Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri. Nahmias Zachary Z Division of Dermatology, Department (...) of Medicine, Washington University School of Medicine, St. Louis, Missouri. eng Case Reports 2018 02 28 United States JAAD Case Rep 101665210 2352-5126 CLH, cutaneous lymphoid hyperplasia immunomodulatory lenalidomide lymphadenosis benigna cutis lymphocytoma cutis pomalidomide pseudolymphoma 2018 4 25 6 0 2018 4 25 6 0 2018 4 25 6 1 epublish 29687061 10.1016/j.jdcr.2018.01.012 S2352-5126(18)30024-9 PMC5909489 Indian J Dermatol. 2016 Jul-Aug;61(4):351-74 27512181 J Am Acad Dermatol. 1996 Dec;35(6):969-79

2018 JAAD Case Reports

5. Hyperplasia of Lymphoid Follicles and Lymphangiectasia in the Parietal Pleura in Bucillamine-induced Yellow Nail Syndrome Full Text available with Trip Pro

Hyperplasia of Lymphoid Follicles and Lymphangiectasia in the Parietal Pleura in Bucillamine-induced Yellow Nail Syndrome Yellow nail syndrome (YNS) pleurisy is often difficult to control, and pathological examinations have rarely been reported. We herein report a case of bucillamine-induced YNS in which histopathology of the parietal pleura revealed hyperplasia of the lymphoid follicles and lymphangiectasia. Even after the discontinuation of bucillamine, the pleurisy and lymphedema showed

2018 Internal Medicine

6. Pulmonary Nodular Lymphoid Hyperplasia in a 33-Year-Old Woman Full Text available with Trip Pro

Pulmonary Nodular Lymphoid Hyperplasia in a 33-Year-Old Woman Pulmonary nodular lymphoid hyperplasia is a reactive lymphoproliferative disease. It is very rare, which means that many aspects of the disease are unknown or have not been proven. Pulmonary nodular lymphoid hyperplasia can be symptomatic or asymptomatic, progressive or not, and solitary or multiple, and a surgical approach is the current treatment of choice. We present a case of pulmonary nodular lymphoid hyperplasia

2018 The Korean journal of thoracic and cardiovascular surgery

7. Benign pulmonary nodular lymphoid hyperplasia (NLH) in an HIV infected patient; A diagnostic dilemma Full Text available with Trip Pro

Benign pulmonary nodular lymphoid hyperplasia (NLH) in an HIV infected patient; A diagnostic dilemma 30456169 2019 02 26 2213-0071 26 2019 Respiratory medicine case reports Respir Med Case Rep Benign pulmonary nodular lymphoid hyperplasia (NLH) in an HIV infected patient; A diagnostic dilemma. 27-30 10.1016/j.rmcr.2018.10.024 Khan Sahoor S Internal Medicine, Catholic Health System, 100 High Street, Buffalo, NY 14203, USA. Ahmed Saman S Division of Pulmonary and Critical Care, University

2018 Respiratory Medicine Case Reports

8. Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature Full Text available with Trip Pro

Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature Reactive lymphoid hyperplasia (RLH) is a rare and benign lesion found in organs of the gastrointestinal tract, skin, lung, orbit, and more rarely in the liver. Due to its similar appearance on imaging, it is hard to differentiate from primary liver malignancies. The following is a case report of a patient presenting with a suspicious liver lesion found to be RLH associated with primary biliary cirrhosis (PBC

2018 Case reports in surgery

9. Topical steroids eye drops in conjunctival reactive lymphoid hyperplasia: Case report. Full Text available with Trip Pro

Topical steroids eye drops in conjunctival reactive lymphoid hyperplasia: Case report. Conjunctival lymphoproliferative lesions constitute a significant diagnostic challenge and it is essential to exclude neoplastic lesions. Histopathological and immunohistochemical tests are very useful in establishing the correct diagnosis. Reactive lymphoid hyperplasia (RLH) is part of a spectrum of lymphocytic infiltrative disorders. Evidence is scarce regarding appropriate treatment of conjunctival RLH. We (...) inflammatory process with conjunctival folicular hyperplasia. The immunohistochemistry examination showed predominance of CD20, CD23, and CD 3 e CD 5.We started topic prednisolone 1% 6 times daily.Six months after starting treatment, the lesion completely resolved, without any side-effects or recurrence during three-year follow-up period.Conjunctival RLH can be managed in various ways, depending on patient symptonm, comorbities, and disease distribution. Surgical resection with cryotherapy, radiotherapy

2017 Medicine

10. Diffuse Nodular Lymphoid Hyperplasia of the Intestine Caused by Common Variable Immunodeficiency and Refractory Giardiasis Full Text available with Trip Pro

Diffuse Nodular Lymphoid Hyperplasia of the Intestine Caused by Common Variable Immunodeficiency and Refractory Giardiasis Diffuse nodular lymphoid hyperplasia of the gastrointestinal tract is a rare disease characterized by numerous small polypoid nodules in the small intestine, large intestine, or both. It is associated with immunodeficiency and infection, such as Giardia lamblia and Helicobacter pylori. Although diffuse nodular lymphoid hyperplasia associated with common variable (...) immunodeficiency (CVID) and giardiasis is already known, a few studies have reported a regression of the lymphoid nodules after the eradication of infection. We herein describe a case of diffuse nodular lymphoid hyperplasia of the intestine associated with CVID and refractory giardiasis that markedly improved after successfully treating giardiasis.

2017 Internal Medicine

11. Thymoma and Synchronous Primary Mediastinal Seminomas with Florid Follicular Lymphoid Hyperplasia in the Anterior Mediastinum: A Case Report and Review of the Literature Full Text available with Trip Pro

Thymoma and Synchronous Primary Mediastinal Seminomas with Florid Follicular Lymphoid Hyperplasia in the Anterior Mediastinum: A Case Report and Review of the Literature Thymoma is the most common neoplasm of the anterior mediastinum and has malignant potential. Germ cell tumors (GCTs) found in the anterior mediastinum are usually benign, and malignant GCTs, such as seminomas, are rare. Histologically, mediastinal seminoma is indistinguishable from testicular seminoma except for site-associated (...) morphological features such as lymphoid follicular hyperplasia. Therefore, excluding metastasis is very important. Recently, we treated a young adult patient with multiple thymic masses that occurred simultaneously. The patient underwent a thymectomy for the removal of the mediastinal masses, one of which was diagnosed as type B2 invasive thymoma, and two of which were diagnosed as primary mediastinal seminomas with massive follicular hyperplasia. The patient received adjuvant chemotherapy after surgical

2017 Journal of Pathology and Translational Medicine

12. T-Cell/Histiocyte-Rich Large B-Cell Lymphoma Presented as T-Lymphoid Hyperplasia Involving the Central Nervous System Full Text available with Trip Pro

T-Cell/Histiocyte-Rich Large B-Cell Lymphoma Presented as T-Lymphoid Hyperplasia Involving the Central Nervous System We herein report a case of T-cell/histiocyte-rich large B-cell lymphoma which initially presented as a self-limiting T-lymphoproliferative disorder involving multiple extranodal and extrapulmonary organs, such as the salivary gland, the liver, and the central nervous system. Repeated biopsies only revealed polyclonal T-lymphocytosis without the presence of atypical B-cells

2017 Cureus

13. Pathogenic mechanism of miR-21 in autoimmune lymphoid hyperplasia syndrome Full Text available with Trip Pro

Pathogenic mechanism of miR-21 in autoimmune lymphoid hyperplasia syndrome miR-21 plays an important role in immune responses and inflammatory diseases, but the mechanism of action of miR-21 in autoimmune lymphoid hyperplasia syndrome still remains unclear. The aim of the present study was to assess the mechanism of miR-21 in autoimmune disease, particularly, the autoimmune lymphoid hyperplasia syndrome. The pathology and immunity-related phenotypes of miR-21 transgenic mice, and the lymphocyte (...) increased double negative T cells were observed in the spleen of the transgenic mice (P<0.05). The immunoglobulins IgG1, IgG2a, IgG2b, and IgG3 in the serum of the transgenic mice aged 8 weeks were significantly higher than those in the wild-type mice aged 8 weeks (P<0.05). The percentages of the GCB cells in the peripheral lymphoid organs such as lymph nodes, mesenteric lymph nodes, PP and spleen in the transgenic mice aged 8-52 weeks increased significantly (P<0.05). The percentage (26.32

2017 Oncology letters

14. Clinicopathological and Ileocolonoscopic Characteristics in Patients with Nodular Lymphoid Hyperplasia in the Terminal Ileum Full Text available with Trip Pro

Clinicopathological and Ileocolonoscopic Characteristics in Patients with Nodular Lymphoid Hyperplasia in the Terminal Ileum Nodular lymphoid hyperplasia (NLH) in the small intestine is a rare benign lesion, characterized by the presence of multiple small nodules on the surface of the intestine. To define the clinicopathological and colonoscopic characteristics in Chinese patients with ileal NLH, we collected 65 patients with NLH in the terminal ileum from the endoscopic database in our (...) hospital and clinical data from medical records. Histology and immunohistochemical staining were performed in the biopsies. The results demonstrated that the main symptoms included diarrhea (70.8%), abdominal pain (60.0%), hematochezia (46.2%), anemia (40.0%), and hypoproteinemia (21.5%). Enteroscopy revealed multiple, sporadic, granular or round-shaped nodules with diameters between 2 and 5 mm in the terminal ileum. The histology revealed the nodules consisted of mass lymphoid follicles in the lamina

2017 International journal of medical sciences

15. Immunodeficiency-Associated Lymphoid Hyperplasia As a Cause of Intussusception in a Case of Activated PI3K-δ Syndrome Full Text available with Trip Pro

Immunodeficiency-Associated Lymphoid Hyperplasia As a Cause of Intussusception in a Case of Activated PI3K-δ Syndrome Activated PI3K-δ syndrome refers to a recently described primary immunodeficiency syndrome consisting of recurrent sinopulmonary infections, lymphadenopathy, mucosal lymphoid aggregates, increased susceptibility to Epstein-Barr virus and cytomegalovirus, and increased incidence of B-cell lymphomas. Variants in PIK3CD, which encodes the phosphatidylinositol-4,5-bisphosphate 3 (...) -kinase catalytic subunit delta isoform, enhance membrane association and kinase activity, resulting in increased signal transduction through the PI3K-Akt pathway. Whole-exome sequencing revealed a pathogenic PIK3CD variant in a patient with history of immunologic impairment, recurrent sinopulmonary infections, and lymphoid hyperplasia presenting as intussusception. This case illustrates that while lymphoid hyperplasia secondary to immunodeficiency is most often unsurprising and non-threatening

2017 Frontiers in pediatrics

16. Comparative Study of microRNA Changes in Patients With Reactive Lymphoid Hyperplasia and Malignant Lymphoma

Comparative Study of microRNA Changes in Patients With Reactive Lymphoid Hyperplasia and Malignant Lymphoma Comparative Study of microRNA Changes in Patients With Reactive Lymphoid Hyperplasia and Malignant Lymphoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Comparative Study of microRNA Changes in Patients With Reactive Lymphoid Hyperplasia and Malignant Lymphoma The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03167476 Recruitment Status : Unknown Verified August 2016 by University

2017 Clinical Trials

17. Nodular Lymphoid Hyperplasia. (Abstract)

Nodular Lymphoid Hyperplasia. 27468084 2016 08 09 2016 07 29 1533-4406 375 3 2016 Jul 21 The New England journal of medicine N. Engl. J. Med. IMAGES IN CLINICAL MEDICINE. Nodular Lymphoid Hyperplasia. e3 10.1056/NEJMicm1514403 Sharma Vishal V Postgraduate Institute of Medical Education and Research, Chandigarh, India docvishalsharma@gmail.com. Ahuja Arvind A Dr. Ram Manohar Lohia Hospital, New Delhi, India. eng Case Reports Journal Article United States N Engl J Med 0255562 0028-4793 AIM IM

2016 NEJM

18. Lymphoid Hyperplasia

Lymphoid Hyperplasia Lymphoid Hyperplasia Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Lymphoid Hyperplasia Lymphoid Hyperplasia (...) Aka: Lymphoid Hyperplasia , Adenoid Hyperplasia II. Pathophysiology Obstructive Lymphoid Hyperplasia Upper airway (Adenoids) Nose III. Signs and symptoms Mouth breathing Severe snoring and intermittent apneas with sleep Occasional "snorts" while awake Accentuated by anatomic high IV. Complications V. Management: Tonsillectomy and Adenoidectomy Surgical removal of excess tissue is curative Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search

2018 FP Notebook

19. Benign reactive lymphoid hyperplasia of the conjunctiva in childhood. (Abstract)

Benign reactive lymphoid hyperplasia of the conjunctiva in childhood. Our aim is to the report the clinical and histopathological features of benign reactive lymphoid hyperplasia (BRLH) of the conjunctiva in children and the outcomes of treatment.A retrospective chart review was performed for children aged 0-18 years, diagnosed with conjunctival BRLH from January 2000 to December 2013 at two large ophthalmology hospitals in the Middle East. Data were collected on patient demographics, features (...) of the lesions, the site of the lesion, location, adnexal involvement, lymph nodes involvement, local spread, histopathology and molecular genetic studies of the cases (if available), outcomes of treatment and recurrence.There were 24 patients with lymphoid lesions classified as conjunctival BRLH during the 12-year period evaluated in this study. The mean age at diagnosis was 11.6 years. Twenty-three patients were males (96%). Systemic medical history included three patients with bronchial asthma, one

2016 British Journal of Ophthalmology

20. Lymphoid Hyperplasia of the Orbit and Ocular Adnexa: A Clinico-Pathological Review. (Abstract)

Lymphoid Hyperplasia of the Orbit and Ocular Adnexa: A Clinico-Pathological Review. Lymphoid hyperplasia (LH) is a benign lymphoproliferative disorder that, in a minority of cases, may be associated with concurrent or metachronous non-Hodgkin lymphoma. LH cases are further subdivided into "reactive" and "atypical" categories based on the presence or absence of unequivocal malignant features. With improving molecular diagnostic technologies, "reactive" LH is by far the most common category of LH

2016 Survey of Ophthalmology

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