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Lymphadenopathy in HIV

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21. Human Immunodeficiency Virus

immunodeficiency virus (HIV) infection (diagnosis) , human T-lymphotropic virus 3 (HTLV-III) infection (diagnosis) , lymphadenopathy-associated virus (diagnosis) , lymphadenopathy-associated virus , human T-lymphotropic virus 3 (HTLV-III) infection , HIV infection NOS , Human immunodeficiency virus infection, unspecified , Human immunodeficiency virus syndrome , Human immuno virus dis , Human immunodeficiency virus [HIV] disease , HIV Infections [Disease/Finding] , Infection;HIV , Human immunodeficiency virus (...) Human Immunodeficiency Virus Aka: Human Immunodeficiency Virus , HIV Infection , Acquired Immunodeficiency Syndrome , AIDS From Related Chapters II. Epidemiology: Global Statistics: WHO HIV : 36.7 M people worldwide (2015) Africa alone accounts for 25.5 M cases Women account for 50% of cases worldwide Children (age<15) account for 1.8 Million cases worldwide HIV : 2.1 M people worldwide (2015) Children (age <15) account for 150,000 new cases per year AIDS AIDS Deaths 1.1 M, of which 110,000 were

2015 FP Notebook

22. Lymphadenopathy in HIV

in HIV Aka: Lymphadenopathy in HIV , Lymphadenitis in HIV II. Causes of Generalized Lymphadenopathy in HIV in (CMV) Cryptococcosis III. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Lymphadenopathy in HIV." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Human Immunodeficiency Virus About FPnotebook.com is a rapid access (...) Lymphadenopathy in HIV Lymphadenopathy in HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Lymphadenopathy in HIV Lymphadenopathy

2018 FP Notebook

23. Immunodeficiency for Severe Epstein-Barr Virus Infection

Immunodeficiency for Severe Epstein-Barr Virus Infection Immunodeficiency for Severe Epstein-Barr Virus Infection - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Immunodeficiency for Severe Epstein-Barr (...) University Information provided by (Responsible Party): Jinqiao Sun, Children's Hospital of Fudan University Study Details Study Description Go to Brief Summary: The purpose of this study is to investigate the immune responses associated with Epstein-Barr virus infections, and to find out the possible immunodeficiency that may be linked to severe Epstein-Barr virus infections. Condition or disease Epstein-Barr Virus Infections Immunodeficiency Detailed Description: Epstein-Barr virus (EBV) belongs

2017 Clinical Trials

24. Human Immunodeficiency Virus (HIV) Infection

Human Immunodeficiency Virus (HIV) Infection Human Immunodeficiency Virus (HIV) Infection - Infectious Diseases - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / IN THIS TOPIC OTHER TOPICS (...) of Tuberculosis (TB) SOCIAL MEDIA Add to Any Platform Loading , MD, MAS, University of California, San Diego Click here for Patient Education NOTE: This is the Professional Version. CONSUMERS: Topic Resources Human immunodeficiency virus (HIV) infection results from 1 of 2 similar retroviruses (HIV-1 and HIV-2) that destroy CD4+ lymphocytes and impair cell-mediated immunity, increasing risk of certain infections and cancers. Initial infection may cause nonspecific febrile illness. Risk of subsequent

2013 Merck Manual (19th Edition)

25. Public health guidance on HIV, hepatitis B and C testing in the EU/EEA

/EEA European Union/European Economic Area GP General practitioner HA-REACT Joint Action on HIV and Co-Infection Prevention and Harm Reduction HBV Hepatitis B virus HBsAg Hepatitis B surface antigen HCV Hepatitis C virus HIV Human immunodeficiency virus IC Indicator condition IFN Interferon INTEGRATE Joint Action on Integrating Prevention, Testing and Linkage to Care Strategies Across HIV, Viral Hepatitis, TB and STIs in Europe IUSTI International Union Against Sexually Transmitted Infections MSM (...) health guidance on HIV, hepatitis B and C testing in the EU/EEA – An integrated approach 1 Executive summary Reaching and testing those at risk of infection with human immunodeficiency virus (HIV), hepatitis B virus (HBV) or hepatitis C virus (HCV) is still a public health challenge across Europe. One in two people currently living with HIV is diagnosed late in the course of their infection and an even larger proportion of the estimated 9 million Europeans living with chronic hepatitis B or C

2019 European Centre for Disease Prevention and Control - Public Health Guidance

26. HIV infection

HIV infection HIV infection - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV infection Last reviewed: February 2019 Last updated: March 2019 Important updates 09 Nov 2018 US guidelines now recommend doravirine for the treatment of HIV Updated guidelines published by the US Department of Health and Human Services now recommend doravirine-based antiretroviral regimens as an initial option for the treatment of HIV (...) therapy (ART) as soon as possible. Pre-exposure prophylaxis with daily ART reduces the risk of HIV infection in adults who are at high risk for HIV acquisition and is recommended in select patients. Diagnosis and management varies between resource-intensive settings and resource-limited settings. Definition HIV infection is a pandemic infectious disease whose impact on societies is without precedent. It is caused by a retrovirus that infects and replicates in human lymphocytes and macrophages, eroding

2018 BMJ Best Practice

27. HIV-related opportunistic infections

Diseases Society of America. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents. May 2018 [internet publication]. https://aidsinfo.nih.gov/guidelines/html/4/adult-and-adolescent-opportunistic-infection/0 History and exam no antiretroviral treatment (ART) or failure of ART fever headache and altered mental status dyspnoea or cough abdominal pain, diarrhoea, weight loss dysphagia lymphadenopathy visual floaters and blindness ocular haemorrhage (...) HIV-related opportunistic infections HIV-related opportunistic infections - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV-related opportunistic infections Last reviewed: February 2019 Last updated: November 2018 Summary The risk of HIV-related opportunistic infections (OIs) in HIV-infected people increases as the CD4+ count declines. Risk also increases in patients who are not receiving, or are not responding

2018 BMJ Best Practice

28. HIV infection in pregnancy

and specialty care provided if the test is positive. All pregnant women with HIV should receive antiretroviral therapy (ART), as early as possible in the pregnancy, regardless of CD4 count or viral load. ART should be administered during the antepartum, intrapartum, and postnatal periods, as well as postnatally to the neonate. Breastfeeding is not recommended unless replacement feeding is not possible or feasible. Definition Human immunodeficiency virus (HIV) is a retrovirus that causes HIV infection (...) by infecting CD4 T cells and can lead to acquired immunodeficiency syndrome (AIDS). Van de Perre P, Simonon A, Msellati P, et al. Postnatal transmission of human immunodeficiency virus type 1 from mother to infant. A prospective cohort study in Kigali, Rwanda. N Engl J Med. 1991 Aug 29;325(9):593-8. http://www.ncbi.nlm.nih.gov/pubmed/1812850?tool=bestpractice.com Pregnancy in women living with HIV is complicated not only by HIV infection itself but also by the medical and psychosocial comorbidities

2018 BMJ Best Practice

29. HIV infection

HIV infection HIV infection - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV infection Last reviewed: February 2019 Last updated: March 2019 Important updates 09 Nov 2018 US guidelines now recommend doravirine for the treatment of HIV Updated guidelines published by the US Department of Health and Human Services now recommend doravirine-based antiretroviral regimens as an initial option for the treatment of HIV (...) therapy (ART) as soon as possible. Pre-exposure prophylaxis with daily ART reduces the risk of HIV infection in adults who are at high risk for HIV acquisition and is recommended in select patients. Diagnosis and management varies between resource-intensive settings and resource-limited settings. Definition HIV infection is a pandemic infectious disease whose impact on societies is without precedent. It is caused by a retrovirus that infects and replicates in human lymphocytes and macrophages, eroding

2018 BMJ Best Practice

30. HIV-related opportunistic infections

Diseases Society of America. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents. May 2018 [internet publication]. https://aidsinfo.nih.gov/guidelines/html/4/adult-and-adolescent-opportunistic-infection/0 History and exam no antiretroviral treatment (ART) or failure of ART fever headache and altered mental status dyspnoea or cough abdominal pain, diarrhoea, weight loss dysphagia lymphadenopathy visual floaters and blindness ocular haemorrhage (...) HIV-related opportunistic infections HIV-related opportunistic infections - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV-related opportunistic infections Last reviewed: February 2019 Last updated: November 2018 Summary The risk of HIV-related opportunistic infections (OIs) in HIV-infected people increases as the CD4+ count declines. Risk also increases in patients who are not receiving, or are not responding

2018 BMJ Best Practice

31. HIV infection in pregnancy

and specialty care provided if the test is positive. All pregnant women with HIV should receive antiretroviral therapy (ART), as early as possible in the pregnancy, regardless of CD4 count or viral load. ART should be administered during the antepartum, intrapartum, and postnatal periods, as well as postnatally to the neonate. Breastfeeding is not recommended unless replacement feeding is not possible or feasible. Definition Human immunodeficiency virus (HIV) is a retrovirus that causes HIV infection (...) by infecting CD4 T cells and can lead to acquired immunodeficiency syndrome (AIDS). Van de Perre P, Simonon A, Msellati P, et al. Postnatal transmission of human immunodeficiency virus type 1 from mother to infant. A prospective cohort study in Kigali, Rwanda. N Engl J Med. 1991 Aug 29;325(9):593-8. http://www.ncbi.nlm.nih.gov/pubmed/1812850?tool=bestpractice.com Pregnancy in women living with HIV is complicated not only by HIV infection itself but also by the medical and psychosocial comorbidities

2018 BMJ Best Practice

32. Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania Full Text available with Trip Pro

Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania Annual mass treatment with ivermectin and albendazole is used to treat lymphatic filariasis in many African countries, including Tanzania. In areas where both diseases occur, it is unclear whether HIV co-infection reduces treatment success.In a general population study in Southwest Tanzania, individuals were tested for HIV and circulating filarial (...) antigen, an indicator of Wuchereria bancrofti adult worm burden, before the first and after 2 consecutive rounds of anti-filarial mass drug administration.Testing of 2104 individuals aged 0-94 years before anti-filarial treatment revealed a prevalence of 24.8% for lymphatic filariasis and an HIV-prevalence of 8.9%. Lymphatic filariasis was rare in children, but prevalence increased in individuals above 10 years, whereas a strong increase in HIV was only seen above 18 years of age. The prevalence

2016 PLoS neglected tropical diseases

33. Isolated bilateral inguinal lymphadenopathy in the absence of other symptoms, due to LGV in known HIV-positive MSM: is it more common than we think? Full Text available with Trip Pro

Isolated bilateral inguinal lymphadenopathy in the absence of other symptoms, due to LGV in known HIV-positive MSM: is it more common than we think? The current resurgence of lymphogranuloma venereum (LGV) has drawn most attention to its potential for causing proctitis; however, this case highlights the need for awareness of LGV as a cause of isolated painful bilateral inguinal lymphadenopathy in a high-risk population and the importance of routine screening for LGV. We describe a case of a 37 (...) -year-old HIV positive man, in the population of men who have sex with men (MSM) who presented with bilateral enlarged inguinal lymph nodes and no other symptoms or signs. Urine nucleic acid amplification test was positive for chlamydia LGV-specific DNA. Tests from other sites were negative. 2016 BMJ Publishing Group Ltd.

2016 BMJ case reports

34. Dolutegravir sodium rilpivirine hydrochloride (Juluca) - HIV Infections

and Drug Administration FDC Fixed-dose combination FI Fluctuation index FMEA Failure mode effects analysis FPV Fosamprenavir FTC Emtricitabine GC Gas chromatography GFR Glomerular filtration rate GLS Geometric Least-Squares GSK GlaxoSmithKline h or hr Hour(s) HBV Hepatitis B virus HCV Hepatitis C virus HDL High-density lipoprotein HDPE High density polyethylene HIV Human immunodeficiency virus HPLC High performance liquid chromatography HSA Human serum albumin IB Investigator’s Brochure IC 50 (...) Dolutegravir sodium rilpivirine hydrochloride (Juluca) - HIV Infections 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5555 Send a question via our website www.ema.europa.eu/contact © European Medicines Agency, 2018. Reproduction is authorised provided the source is acknowledged. 22 March 2018 EMA/243517/2018 Committee for Medicinal Products for Human Use (CHMP) Assessment report Juluca

2018 European Medicines Agency - EPARs

35. Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system Full Text available with Trip Pro

Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system The intestinal lymphatic system plays an important role in the pathophysiology of multiple diseases including lymphomas, cancer metastasis, autoimmune diseases, and human immunodeficiency virus (HIV) infection. It is thus an important compartment for delivery of drugs in order to treat diseases associated with the lymphatic system. Lipophilic prodrug approaches have been used in the past to take (...) advantage of the intestinal lymphatic transport processes to deliver drugs to the intestinal lymphatics. Most of the approaches previously adopted were based on very bulky prodrug moieties such as those mimicking triglycerides (TG). We now report a study in which a lipophilic prodrug approach was used to efficiently deliver bexarotene (BEX) and retinoic acid (RA) to the intestinal lymphatic system using activated ester prodrugs. A range of carboxylic ester prodrugs of BEX were designed and synthesised

2018 Journal of Controlled Release

36. Cat-Scratch Disease in an AIDS Patient Presenting with Generalized Lymphadenopathy: An Unusual Presentation with Delayed Diagnosis Full Text available with Trip Pro

Cat-Scratch Disease in an AIDS Patient Presenting with Generalized Lymphadenopathy: An Unusual Presentation with Delayed Diagnosis BACKGROUND Bartonella infection is the causative organism of cat-scratch disease (CSD), which typically presents with self-limited localized lymphadenopathy. In HIV-infected patients, Bartonella infection can cause systemic illnesses with significant morbidity and mortality manifesting as bacillary angiomatosis (BA), hepatic peliosis, splenitis, bacteremic febrile (...) illness, and other organ involvement. To the best of our knowledge, there have been no reports of HIV-infected patients presenting with generalized lymphadenopathy caused by Bartonella infection. We report an unusual case of CSD presenting with generalized lymphadenopathy in an AIDS patient with advanced immunosuppression. CASE REPORT A 44-year-old woman with AIDS, advanced immunosuppression, and intermittent adherence to antiretroviral therapy and medical care, presented with cough and increased

2018 The American journal of case reports

37. Survival of non-transplant patients with multiple myeloma in routine care differs from that in clinical trials—data from the prospective German Tumour Registry Lymphatic Neoplasms Full Text available with Trip Pro

, and survival of non-transplant patients with MM treated in German routine care. The prospective clinical cohort study TLN (Tumour Registry Lymphatic Neoplasms) recruited 285 non-transplant patients with symptomatic MM at start of first-line treatment in 84 centres from 2009 to 2011. Demographic and clinical data were collected until August 2016. Trial-ineligibility was determined by presence of at least one of the common exclusion criteria: heart/renal failure, liver/renal diseases, polyneuropathy, HIV (...) Survival of non-transplant patients with multiple myeloma in routine care differs from that in clinical trials—data from the prospective German Tumour Registry Lymphatic Neoplasms Despite increasing treatment options, multiple myeloma (MM) remains incurable for most patients. Data on improvement of outcomes are derived from selected patient populations enrolled in clinical trials and might not be conferrable to all patients. Therefore, we assessed the trial eligibility, sequential treatment

2018 Annals of hematology

38. The Meningeal Lymphatic System: A Route for HIV Brain Migration? Full Text available with Trip Pro

The Meningeal Lymphatic System: A Route for HIV Brain Migration? Two innovative studies recently identified functional lymphatic structures in the meninges that may influence the development of HIV-associated neurological disorders (HAND). Until now, blood vessels were assumed to be the sole transport system by which HIV-infected monocytes entered the brain by bypassing a potentially hostile blood-brain barrier through inflammatory-mediated semi-permeability. A cascade of specific chemokine (...) signals promote monocyte migration from blood vessels to surrounding brain tissues via a well-supported endothelium, where the cells differentiate into tissue macrophages capable of productive HIV infection. Lymphatic vessels on the other hand are more loosely organized than blood vessels. They absorb interstitial fluid from bodily tissues where HIV may persist and exchange a variety of immune cells (CD4(+) T cells, monocytes, macrophages, and dendritic cells) with surrounding tissues through

2015 Journal of neurovirology

39. Derivation and Characterization of Pathogenic Transmitted/Founder Molecular Clones from Simian Immunodeficiency Virus SIVsmE660 and SIVmac251 following Mucosal Infection Full Text available with Trip Pro

in progressive CD4(+) T cell loss in gastrointestinal tissues, peripheral blood, and lymphatic tissues. The animals developed pathological immune activation; lymphoid tissue damage, including fibrosis; and clinically significant immunodeficiency leading to AIDS-defining clinical endpoints. These T/F clones represent a new molecular platform for the analysis of virus transmission and immunopathogenesis and for the generation of novel "bar-coded" challenge viruses and next-generation simian-human (...) immunodeficiency viruses that may advance the HIV/AIDS vaccine agenda.Nonhuman primate research has relied on only a few infectious molecular clones for a myriad of diverse research projects, including pathogenesis, preclinical vaccine evaluations, transmission, and host-versus-pathogen interactions. With new data suggesting a selected phenotype of the virus that causes infection (i.e., the transmitted/founder virus), we sought to generate and characterize infectious molecular clones from two widely used

2016 Journal of virology

40. Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru. Full Text available with Trip Pro

Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru. The differential diagnosis for lymphadenopathy is wide and clinical presentations overlap, making obtaining an accurate diagnosis challenging. We sought to characterize the clinical and radiological characteristics, histological findings, and diagnoses for a cohort of patients with lymphadenopathy of unknown etiology. 121 Peruvian adults with lymphadenopathy underwent lymph node biopsy (...) for microbiological and histopathological evaluation. Mean patient age was 41 years (Interquartile Range 26-52), 56% were males, and 39% were HIV positive. Patients reported fever (31%), weight loss (23%), and headache (22%); HIV infection was associated with fever (P < 0.05) and gastrointestinal symptoms (P < 0.05). Abnormalities were reported in 40% of chest X-rays (N = 101). Physicians suspected TB in 92 patients (76%), lymphoma in 19 patients (16%), and other malignancy in seven patients (5.8%). Histological

2017 American Journal of Tropical Medicine & Hygiene

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