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Lymphadenopathy in HIV

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1. Assessment of lymphadenopathy

=bestpractice.com Brown JR, Skarin AT. Clinical mimics of lymphoma. Oncologist. 2004;9(4):406-16. http://theoncologist.alphamedpress.org/cgi/reprint/9/4/406.pdf http://www.ncbi.nlm.nih.gov/pubmed/15266094?tool=bestpractice.com Differentials Infectious mononucleosis (Epstein-Barr virus) HIV Adenovirus Cytomegalovirus (CMV) Herpes zoster (shingles) Streptococcal pharyngitis Non-Hodgkin's lymphoma Hodgkin's lymphoma Chronic lymphocytic leukaemia (CLL) Metastatic solid tumour Drug-associated lymphadenopathy Serum (...) Assessment of lymphadenopathy Assessment of lymphadenopathy - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of lymphadenopathy Last reviewed: February 2019 Last updated: August 2018 Summary Lymphadenopathy is defined as lymph nodes that are abnormal in size, consistency or number. The extent of lymphadenopathy is defined as localised, regional or generalised. Lymphadenopathy is commonly encountered

2018 BMJ Best Practice

2. A 32-Year-Old Man With HIV Infection, Pleural Effusions, and Lymphadenopathy. (PubMed)

A 32-Year-Old Man With HIV Infection, Pleural Effusions, and Lymphadenopathy. A 32-year-old man presented with fever, nonproductive cough, diffuse lymphadenopathy, and polyarticular pain for 2 weeks. His medical history included HIV diagnosed 10 years ago, anal intraepithelial neoplasia, Kaposi sarcoma, and herpes simplex virus-2 infection. The patient was not receiving antiretroviral therapy or antibiotic prophylaxis, and his last known CD4 count a month before was 45 cells/mm3. He

2018 Chest

3. Lymphadenopathy in HIV

Lymphadenopathy in HIV Lymphadenopathy in HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Lymphadenopathy in HIV Lymphadenopathy (...) in HIV Aka: Lymphadenopathy in HIV , Lymphadenitis in HIV II. Causes of Generalized Lymphadenopathy in HIV in (CMV) Cryptococcosis III. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Lymphadenopathy in HIV." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Human Immunodeficiency Virus About FPnotebook.com is a rapid access

2018 FP Notebook

4. Isolated bilateral inguinal lymphadenopathy in the absence of other symptoms, due to LGV in known HIV-positive MSM: is it more common than we think? (PubMed)

Isolated bilateral inguinal lymphadenopathy in the absence of other symptoms, due to LGV in known HIV-positive MSM: is it more common than we think? The current resurgence of lymphogranuloma venereum (LGV) has drawn most attention to its potential for causing proctitis; however, this case highlights the need for awareness of LGV as a cause of isolated painful bilateral inguinal lymphadenopathy in a high-risk population and the importance of routine screening for LGV. We describe a case of a 37 (...) -year-old HIV positive man, in the population of men who have sex with men (MSM) who presented with bilateral enlarged inguinal lymph nodes and no other symptoms or signs. Urine nucleic acid amplification test was positive for chlamydia LGV-specific DNA. Tests from other sites were negative. 2016 BMJ Publishing Group Ltd.

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2016 BMJ case reports

5. Cat-Scratch Disease in an AIDS Patient Presenting with Generalized Lymphadenopathy: An Unusual Presentation with Delayed Diagnosis (PubMed)

Cat-Scratch Disease in an AIDS Patient Presenting with Generalized Lymphadenopathy: An Unusual Presentation with Delayed Diagnosis BACKGROUND Bartonella infection is the causative organism of cat-scratch disease (CSD), which typically presents with self-limited localized lymphadenopathy. In HIV-infected patients, Bartonella infection can cause systemic illnesses with significant morbidity and mortality manifesting as bacillary angiomatosis (BA), hepatic peliosis, splenitis, bacteremic febrile (...) illness, and other organ involvement. To the best of our knowledge, there have been no reports of HIV-infected patients presenting with generalized lymphadenopathy caused by Bartonella infection. We report an unusual case of CSD presenting with generalized lymphadenopathy in an AIDS patient with advanced immunosuppression. CASE REPORT A 44-year-old woman with AIDS, advanced immunosuppression, and intermittent adherence to antiretroviral therapy and medical care, presented with cough and increased

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2018 The American journal of case reports

6. Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru. (PubMed)

Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru. The differential diagnosis for lymphadenopathy is wide and clinical presentations overlap, making obtaining an accurate diagnosis challenging. We sought to characterize the clinical and radiological characteristics, histological findings, and diagnoses for a cohort of patients with lymphadenopathy of unknown etiology. 121 Peruvian adults with lymphadenopathy underwent lymph node biopsy (...) for microbiological and histopathological evaluation. Mean patient age was 41 years (Interquartile Range 26-52), 56% were males, and 39% were HIV positive. Patients reported fever (31%), weight loss (23%), and headache (22%); HIV infection was associated with fever (P < 0.05) and gastrointestinal symptoms (P < 0.05). Abnormalities were reported in 40% of chest X-rays (N = 101). Physicians suspected TB in 92 patients (76%), lymphoma in 19 patients (16%), and other malignancy in seven patients (5.8%). Histological

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2017 American Journal of Tropical Medicine & Hygiene

7. Indian visceral leishmaniasis with extensive lymphadenopathy – An unusual presentation: A case report with literature review (PubMed)

Indian visceral leishmaniasis with extensive lymphadenopathy – An unusual presentation: A case report with literature review Visceral leishmaniasis (VL), also known as kala-azar, is a life-threatening systemic disease caused by the obligate intracellular protozoan, Leishmania, and transmitted to humans by the female phlebotomine sand fly (Phlebotomus argentipes). The disease is fatal, if left untreated. We report a case of a patient clinically suspected of disseminated tuberculosis, but fine (...) needle aspiration cytology of cervical and axillary lymph nodes yielded a diagnosis of leishmaniasis. Diagnosis of VL was challenging as the disease closely mimicked tuberculosis in the setting of extensive lymphadenopathy including conglomerate of mesenteric lymph nodes, on and off fever, and granulomatous lymphadenitis on aspiration. Bone marrow examination was further performed. A detailed workup revealed patient to be severely immunocompromised and newly diagnosed human immunodeficiency virus

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2017 CytoJournal

8. Public health guidance on HIV, hepatitis B and C testing in the EU/EEA

Public health guidance on HIV, hepatitis B and C testing in the EU/EEA SCIENTIFIC AD VICE www.ecdc.europa.eu Public health guidance on HIV, hepatitis B and C testing in the EU/EEA An integrated approachECDC SCIENTIFIC ADVICE Public health guidance on HIV, hepatitis B and C testing in the EU/EEA An integrated approach ii This guidance was commissioned by the European Centre for Disease Prevention and Control (ECDC), coordinated by Andrew J Amato-Gauci and Lara Tavoschi with the support of Helena (...) , Correlation Network, Choices Support Center, Netherlands Jens Lundgren, CHIP/Region H, Denmark Jessika Deblonde, Sciensano, Belgium Jordi Casabona, Center of Epidemiological Studies on HIV and STI in Catalonia (CEEISCAT), Spain Justyna Kowalska, Medical University of Warsaw, Poland Kristi Rüütel, National Institute for Health Development, Estonia Maria Axelsson, Public Health Agency of Sweden, Sweden Maria Elena Tosti, Istituto Superiore di Sanità, Italy Matthew Hickman, University of Bristol, United

2019 European Centre for Disease Prevention and Control - Public Health Guidance

9. High prevalence of malignancy in HIV-positive patients with mediastinal lymphadenopathy: a study in the era of antiretroviral therapy. (PubMed)

High prevalence of malignancy in HIV-positive patients with mediastinal lymphadenopathy: a study in the era of antiretroviral therapy. Mediastinal lymphadenopathy (MLN) in human immunodeficiency virus (HIV) infection has a wide spectrum of aetiologies with different prognoses and treatments. The decision to pursue a histopathological diagnosis represents a clinical challenge as patients present with non-specific symptoms. This study aimed to determine the aetiology and predictive factors of MLN (...) in a cohort of HIV-infected patients in the combination antiretroviral therapy (cART) era.Single-centre retrospective cohort study of 217 consecutive HIV-infected patients who underwent computed tomography (CT) of the chest between January 2004 and December 2009. Fifty-two patients were identified to have MLN (>10 mm in short axis). CT images were re-reviewed by an independent radiologist blinded to the clinical information. Final diagnoses of MLN were obtained from clinical records. Multivariate analysis

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2014 Respirology

10. HIV-related opportunistic infections

Diseases Society of America. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents. May 2018 [internet publication]. https://aidsinfo.nih.gov/guidelines/html/4/adult-and-adolescent-opportunistic-infection/0 History and exam no antiretroviral treatment (ART) or failure of ART fever headache and altered mental status dyspnoea or cough abdominal pain, diarrhoea, weight loss dysphagia lymphadenopathy visual floaters and blindness ocular haemorrhage (...) HIV-related opportunistic infections HIV-related opportunistic infections - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV-related opportunistic infections Last reviewed: February 2019 Last updated: November 2018 Summary The risk of HIV-related opportunistic infections (OIs) in HIV-infected people increases as the CD4+ count declines. Risk also increases in patients who are not receiving, or are not responding

2018 BMJ Best Practice

11. HIV-related opportunistic infections

Diseases Society of America. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents. May 2018 [internet publication]. https://aidsinfo.nih.gov/guidelines/html/4/adult-and-adolescent-opportunistic-infection/0 History and exam no antiretroviral treatment (ART) or failure of ART fever headache and altered mental status dyspnoea or cough abdominal pain, diarrhoea, weight loss dysphagia lymphadenopathy visual floaters and blindness ocular haemorrhage (...) HIV-related opportunistic infections HIV-related opportunistic infections - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV-related opportunistic infections Last reviewed: February 2019 Last updated: November 2018 Summary The risk of HIV-related opportunistic infections (OIs) in HIV-infected people increases as the CD4+ count declines. Risk also increases in patients who are not receiving, or are not responding

2018 BMJ Best Practice

12. HIV infection

HIV infection HIV infection - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV infection Last reviewed: February 2019 Last updated: March 2019 Important updates 09 Nov 2018 US guidelines now recommend doravirine for the treatment of HIV Updated guidelines published by the US Department of Health and Human Services now recommend doravirine-based antiretroviral regimens as an initial option for the treatment of HIV (...) -nucleoside reverse transcriptase inhibitor (NNRTI), was approved by the US Food and Drug Administration in August 2018 in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults with no prior antiretroviral treatment history. The drug is available as a single-ingredient formulation or in a co-formulation with lamivudine and tenofovir disoproxil. It has also been recommended for approval in Europe, with a final decision pending. Approval was based on two clinical trials

2018 BMJ Best Practice

13. HIV infection in pregnancy

associated with HIV. HIV infection in pregnancy poses a threat to maternal immune health and can lead to perinatal transmission of HIV in utero, intrapartum, or through breastfeeding postnatal. History and exam increased risk of maternal HIV infection increased risk of perinatal HIV transmission oral candidiasis increasing dyspnoea weight loss fever malaise lymphadenopathy maculopapular blanching rash needle-sharing with injection drug use receptive penile-vaginal intercourse unprotected receptive anal (...) HIV infection in pregnancy HIV infection in pregnancy - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV infection in pregnancy Last reviewed: February 2019 Last updated: December 2018 Important updates 18 Dec 2018 Dolutegravir should not be used during the first trimester of pregnancy The US Department of Health and Human Services has updated its guidance on the management of pregnant women living with HIV

2018 BMJ Best Practice

14. HIV infection

HIV infection HIV infection - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV infection Last reviewed: February 2019 Last updated: March 2019 Important updates 09 Nov 2018 US guidelines now recommend doravirine for the treatment of HIV Updated guidelines published by the US Department of Health and Human Services now recommend doravirine-based antiretroviral regimens as an initial option for the treatment of HIV (...) -nucleoside reverse transcriptase inhibitor (NNRTI), was approved by the US Food and Drug Administration in August 2018 in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults with no prior antiretroviral treatment history. The drug is available as a single-ingredient formulation or in a co-formulation with lamivudine and tenofovir disoproxil. It has also been recommended for approval in Europe, with a final decision pending. Approval was based on two clinical trials

2018 BMJ Best Practice

15. HIV infection in pregnancy

associated with HIV. HIV infection in pregnancy poses a threat to maternal immune health and can lead to perinatal transmission of HIV in utero, intrapartum, or through breastfeeding postnatal. History and exam increased risk of maternal HIV infection increased risk of perinatal HIV transmission oral candidiasis increasing dyspnoea weight loss fever malaise lymphadenopathy maculopapular blanching rash needle-sharing with injection drug use receptive penile-vaginal intercourse unprotected receptive anal (...) HIV infection in pregnancy HIV infection in pregnancy - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  HIV infection in pregnancy Last reviewed: February 2019 Last updated: December 2018 Important updates 18 Dec 2018 Dolutegravir should not be used during the first trimester of pregnancy The US Department of Health and Human Services has updated its guidance on the management of pregnant women living with HIV

2018 BMJ Best Practice

16. Regional Lymphadenopathy

Lymphadenopathy Aka: Regional Lymphadenopathy , Inguinal Lymphadenopathy , Axillary Lymphadenopathy , Epitrochlear Lymphadenopathy , Supraclavicular Lymphadenopathy , Regional Lymphadenitis From Related Chapters II. Causes: Tender Regional Unilateral Lymphadenopathy (CMV) (EBV, ) Humn (HIV) (and other non-tuberculous ) (children) III. Causes: Right Supraclavicular Nodes Drainage Patterns Mediastinum s Esophagus Gastrointestinal cancer Cancer of the IV. Causes: Left Supraclavicular Nodes Drainage Patterns (...) Regional Lymphadenopathy Regional Lymphadenopathy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Regional Lymphadenopathy Regional

2018 FP Notebook

17. Lymphadenopathy in the Febrile Returning Traveler

Administration 4 Lymphadenopathy in the Febrile Returning Traveler Lymphadenopathy in the Febrile Returning Traveler Aka: Lymphadenopathy in the Febrile Returning Traveler , Lymphadenitis in the Febrile Returning Traveler II. Differential Diagnosis III. Causes: Regional Lymphadenopathy s African and IV. Causes: Generalized Lymphadenopathy ( ) es (HIV) Fungus s V. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Lymphadenopathy (...) Lymphadenopathy in the Febrile Returning Traveler Lymphadenopathy in the Febrile Returning Traveler Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer

2018 FP Notebook

18. A Patient with Supraclavicular Lymphadenopathy and Anterior Mediastinal Mass Presenting as a Rare Case of Composite Lymphoma: A Case Report and Literature Review (PubMed)

A Patient with Supraclavicular Lymphadenopathy and Anterior Mediastinal Mass Presenting as a Rare Case of Composite Lymphoma: A Case Report and Literature Review Composite lymphoma (CL) is a rare disease with 2 distinct lymphomas concurrently arising in a single patient with an estimated incidence of 1-4.7% of newly diagnosed lymphomas per year. CL most commonly involves 2 B-cell non-Hodgkin lymphomas (NHL) or a B-cell NHL with a Hodgkin lymphoma. Our case is unique in that it was a bilineage (...) CL with both a T-cell and B-cell NHL, which has only been reported in a few case reports. A 49-year-old woman presented with several months of progressive cough, weight loss, dyspnea, and supraclavicular lymphadenopathy. Computed tomographic imaging done upon admission to the hospital found that she had extensive anterior and middle mediastinal lymphadenopathy as well as bilateral supraclavicular lymphadenopathy. The patient underwent an excisional biopsy on the supraclavicular lymph node

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2016 Case reports in oncology

19. Endemic Kaposi sarcoma in HIV-negative children and adolescents: an evaluation of overlapping and distinct clinical features in comparison with HIV-related disease (PubMed)

anemia (hemoglobin < 8 g/dL) and thrombocytopenia (platelet count < 100 × 109/L) were found at time of original KS diagnosis in 45 and 40% respectively. In both HIV-negative and HIV-positive cohorts, lymphadenopathy was the most common presentation, prototypical skin lesions were often absent, severe cytopenias were a common clinical feature, and treatment outcomes were similar. Patients with endemic KS demonstrated less frequent oral involvement (5% versus 29%, P = 0.03) and a lower proportion (...) Endemic Kaposi sarcoma in HIV-negative children and adolescents: an evaluation of overlapping and distinct clinical features in comparison with HIV-related disease Endemic Kaposi sarcoma (KS) was first described in African children over fifty years ago, but has recently been overshadowed by HIV-related disease. We aimed to evaluate the similarities and differences between endemic HIV-negative and epidemic HIV-positive pediatric KS in a KS-associated herpesvirus-endemic region of Africa.We

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2018 Infectious agents and cancer

20. Dolutegravir rilpivirine (Juluca) - For the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults who are virologically suppressed (HIV-1 RNA copies <50 copies/mL) on a stable antiretroviral regimen

A (asymptomatic, lymphadenopathy or acute HIV). It is not known if the same results would be seen in patients with more advanced disease; (category B = symptomatic, not AIDS; category C = AIDS). 2 The DEXA sub-study found a significant increase in mean bone mineral density from baseline to week 48 in patients who switched from a triple antiretroviral regimen containing tenofovir disoproxil fumarate to dolutegravir plus rilpivirine compared with those who continued on treatment with tenofovir disoproxil (...) Dolutegravir rilpivirine (Juluca) - For the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults who are virologically suppressed (HIV-1 RNA copies <50 copies/mL) on a stable antiretroviral regimen Published 10 September 2018 1 dolutegravir 50mg / rilpivirine 25mg film-coated tablets (Juluca ® ) SMC2091 ViiV Healthcare Ltd. 10 August 2018 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug

2018 Scottish Medicines Consortium

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