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Lumbar Disc Herniation

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1. Incidence of early postoperative complications requiring surgical revision for recurrent lumbar disc herniation after spinal surgery: a retrospective observational study of 9,310 patients from the German Spine Register Full Text available with Trip Pro

Incidence of early postoperative complications requiring surgical revision for recurrent lumbar disc herniation after spinal surgery: a retrospective observational study of 9,310 patients from the German Spine Register The recurrence rate in lumbar disc herniations (LDH) has been reported between 5 and 25%. There are only few data about this phenomenon that occurs within days of the initial operation. We analyse early recurrent LDH by analysis of data from the German Spine register.Data from (...) patients undergoing disc herniation surgery in the lumbar region were extracted from the German Spine Registry between 1st January 2012 and 31st December 2016. Patients with early recurrent LDH within days of initial surgery were separately analysed.A total of 9310 surgeries for LDH were documented in the German Spine Register. From these patients 115 (1.2%) presented an early recurrent disc surgeries within days of the initial surgery. The mean age was 70 ± 2.50 years. Most affected segment was L4/5

2018 Patient safety in surgery

2. Percutaneous endoscopic lumbar discectomy for primary lumbar disc herniation

Percutaneous endoscopic lumbar discectomy for primary lumbar disc herniation Percutaneous endoscopic lumbar discectomy for primary lumbar disc herniation Percutaneous endoscopic lumbar discectomy for primary lumbar disc herniation HAYES, Inc Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc. Percutaneous endoscopic lumbar discectomy for primary lumbar (...) disc herniation. Lansdale: HAYES, Inc. Healthcare Technology Brief Publication. 2017 Authors' conclusions Lumbar disc herniation (LDH) occurs when a tear in the outer fibrous ring of an intervertebral disc allows prolapse of the softer central nucleus pulposus portion. Disc herniation may also occur when the outer fibrous ring is intact but bulges under pressure. Surgical intervention for LDH is indicated when severe lower back pain, leg pain, or both are refractory to conservative treatment

2017 Health Technology Assessment (HTA) Database.

3. Laser Spine Surgery for Herniated Discs and/or Nerve Root Entrapment: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines

eligible guideline from the United States did not state any recommendation with regard to percutaneous lumbar laser disc decompression due to a lack of high-quality evidence. Tags diskectomy, intervertebral disc displacement, laser therapy, minimally invasive surgical procedures, nerve compression syndromes, radiculopathy, spinal diseases, spinal nerve roots, spine, surgery, discectomy, back surgery, nerve compression, trapped nerve, Laser Files Rapid Response Summary with Critical Appraisal Published (...) Laser Spine Surgery for Herniated Discs and/or Nerve Root Entrapment: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines Laser Spine Surgery for Herniated Discs and/or Nerve Root Entrapment: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines | CADTH.ca Find the information you need Laser Spine Surgery for Herniated Discs and/or Nerve Root Entrapment: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines Laser Spine Surgery for Herniated

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

4. Cost Utility Analysis of Lumbar Interlaminar Epidural Injections in the Treatment of Lumbar Disc Herniation, Central Spinal Stenosis, and Axial or Discogenic Low Back Pain (Abstract)

procedures and physician visits were assessed based on the data, with extrapolation of indirect costs presenting the overall total costs. The benefits of returning to work were not assessed.This cost utility analysis of lumbar interlaminar epidural injections in patients nonresponsive to conservative management in the treatment of disc herniation, central spinal stenosis, and axial or discogenic low back pain in the lumbar spine shows the clinical effectiveness and cost utility of these injections (...) Cost Utility Analysis of Lumbar Interlaminar Epidural Injections in the Treatment of Lumbar Disc Herniation, Central Spinal Stenosis, and Axial or Discogenic Low Back Pain Cost utility or cost effective analysis continues to take center stage in the United States for defining and measuring the value of treatments in interventional pain management. Appropriate cost utility analysis has been performed for caudal epidural injections, percutaneous adhesiolysis, and spinal cord stimulation. However

2017 EvidenceUpdates

5. Cost utility analysis of caudal epidural injections in the treatment of lumbar disc herniation, axial or discogenic low back pain, central spinal stenosis, and post lumbar surgery syndrome

Cost utility analysis of caudal epidural injections in the treatment of lumbar disc herniation, axial or discogenic low back pain, central spinal stenosis, and post lumbar surgery syndrome Cost utility analysis of caudal epidural injections in the treatment of lumbar disc herniation, axial or discogenic low back pain, central spinal stenosis, and post lumbar surgery syndrome Cost utility analysis of caudal epidural injections in the treatment of lumbar disc herniation, axial or discogenic low (...) epidural injections in the treatment of lumbar disc herniation, axial or discogenic low back pain, central spinal stenosis, and post lumbar surgery syndrome. Pain Physician 2013; 16(3): E129-E143 PubMedID Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Adult; Aged; Costs and Cost Analysis; Disability Evaluation; Female; Follow-Up Studies; Humans; Injections, Epidural /economics /methods; Intervertebral Disc Displacement /drug therapy /economics; Low Back Pain /drug therapy

2013 NHS Economic Evaluation Database.

6. Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 8: Lumbar fusion for disc herniation and radiculopathy

Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 8: Lumbar fusion for disc herniation and radiculopathy J Neurosurg Spine 21:48–53, 2014 48 ©AANS, 2014 J Neurosurg: Spine / Volume 21 / July 2014 Recommendations There is no evidence that conflicts with the previous recommendations formulated from the first generation of the Lumbar Fusion Guidelines. Grade C Lumbar spinal fusion is not recommended as a rou- tine treatment following (...) pain. (http://thejns.org/doi/abs/10.3171/2014.4.SPINE14271) Key WorDs • fusion • lumbar spineherniated disc • practice guidelines Abbreviations used in this paper: JOA = Japanese Orthopaedic Association; LHNP = lumbar herniated nucleus pulposus; ODI = Oswestry Disability Index.Part 8: Lumbar fusion for disc herniation and radiculopathy 49 J Neurosurg: Spine / Volume 21 / July 2014 of the spinal nerve, lumbar discectomy has become the established surgical procedure in cases in which conser

2014 Congress of Neurological Surgeons

7. SFKs/p38 Pathway is Involved in Radicular Pain by Promoting Spinal Expression of Pro-Inflammatory Cytokines in a Rat Model of Lumbar Disc Herniation. (Abstract)

SFKs/p38 Pathway is Involved in Radicular Pain by Promoting Spinal Expression of Pro-Inflammatory Cytokines in a Rat Model of Lumbar Disc Herniation. MINI: Lumbar disc herniation always generates radicular pain and mechanism is not clear. In this study, we found spinal SFKs contributed to radicular pain by activating of p38 MAPK and increasing pro-inflammatory cytokines expression in rats with NP implantation. Targeting SFKs/p38 pathway may be helpful for alleviating radicular pain.Controlled (...) , randomized, animal study.To investigate the role of src-family kinases/p38 pathway in a rat model of lumbar disc herniation (LDH).LDH always generates radicular pain, and the mechanism remains unclear. We have reported spinal src-family kinases (SFKs) may be involved in the process, but the downstream mechanism needs further investigation.LDH was induced by implantation of autologous nucleus pulposus (NP), harvest from the tail, in lumbar 4/5 spinal nerve roots of rat. Von Frey filaments and radiant heat

2019 Spine

8. Normalization of Spinal Cord Displacement with the Straight leg Raise and Resolution of Sciatica in Patients with Lumbar Intervertebral Disc Herniation: A 1.5-Year Follow-up Study. (Abstract)

Normalization of Spinal Cord Displacement with the Straight leg Raise and Resolution of Sciatica in Patients with Lumbar Intervertebral Disc Herniation: A 1.5-Year Follow-up Study. Controlled radiologic follow-up study.To ascertain if changes in cord excursion with SLR at 1.5-year follow-up time accompany changes in clinical symptoms SUMMARY OF BACKGROUND DATA.: Lumbar intervertebral disc herniation (LIDH) is known to be a key cause of sciatica. Previously we found that a significant limitation

2019 Spine Controlled trial quality: uncertain

9. Clinical research on the efficacy and safety of thread-embedding acupuncture for treatment of herniated intervertebral disc of the lumbar spine: a protocol for a multicenter, randomized, patient–assessor blinded, controlled, parallel, clinical trial Full Text available with Trip Pro

Clinical research on the efficacy and safety of thread-embedding acupuncture for treatment of herniated intervertebral disc of the lumbar spine: a protocol for a multicenter, randomized, patient–assessor blinded, controlled, parallel, clinical trial A lumbar herniated intervertebral disc (LHIVD) is a common problem that usually causes lower back pain and neurological symptoms that manifest as radiating pain. Several studies have reported that thread-embedding acupuncture (TEA) is effective

2018 Trials Controlled trial quality: predicted high

10. Is Facet Tropism Associated with Increased Risk of Disc Herniation in the Lumbar Spine? Full Text available with Trip Pro

Is Facet Tropism Associated with Increased Risk of Disc Herniation in the Lumbar Spine? Retrospective case control study.In current study, we compared the incidence of facet tropism (FT) in patients with lumbar disc herniation and normal controls.It has been suggested that FT can be associated with increased risk of lumbar disc herniation.A total of 66 and 63 patients with L4/L5 and L5/S1 disc herniation, respectively, were evaluated in the present study. The control group comprised 61 normal (...) subjects. Facet joint angle was measured using axial magnetic resonance images. The FT was defined as a difference of >10° between the right and left facet joints. The incidence of FT was compared between patients and controls. We also investigated the relationship between facet orientation (sagittal or coronal) and side of disc herniation.The incidence of FT at the L4/L5 level was significantly higher in patients with disc herniation (48.5% vs. 26.2%, p =0.01), while it was found to be the same

2018 Asian spine journal

11. Accuracy of the kissing sign on lumbar spine MRI in cases of axillary disc herniation and the surgical correlation: an Indian multi-center study Full Text available with Trip Pro

Accuracy of the kissing sign on lumbar spine MRI in cases of axillary disc herniation and the surgical correlation: an Indian multi-center study Magnetic resonance imaging has proven to be a valuable tool in the assessment of disc abnormalities. Two types of disc extrusion can be described according to the direction of herniated disc material: shoulder type and axillary type. Axillary disc herniation is described when the extruded disc fragment lies in the recess between the lateral border (...) of cauda equina and medial to the nerve roots, while in the shoulder type the disc lies lateral to the nerve roots. It is very important to describe the type of disc herniation, as the surgical approach differs in each type. To the best of the authors' knowledge, no definite signs have been described in literature to date. This study aimed to address the accuracy of the kissing sign on MRI for he diagnosis of axillary disc herniation.The MRIs of 72 patients undergoing spinal surgery were prospectively

2018 Revista brasileira de ortopedia

12. Clinical research on the efficacy and safety of Bosinji for low back pain with radiculopathy caused by herniated intervertebral disc of the lumbar spine: A protocol for a multicenter, randomized, controlled equivalence trial. Full Text available with Trip Pro

Clinical research on the efficacy and safety of Bosinji for low back pain with radiculopathy caused by herniated intervertebral disc of the lumbar spine: A protocol for a multicenter, randomized, controlled equivalence trial. A lumbar herniated intervertebral disc (LHIVD) is a common problem that usually causes low back pain and radiating pain. The effectiveness of Bosinji, one of the herbal medicines used for low back pain and radiating pain in patient with LHIVD, has been reported in several

2018 Medicine Controlled trial quality: uncertain

13. Effects of Adding a Neurodynamic Mobilization to Motor Control Training in Patients with Lumbar Radiculopathy due to Disc Herniation: A Randomized Clinical Trial. (Abstract)

Effects of Adding a Neurodynamic Mobilization to Motor Control Training in Patients with Lumbar Radiculopathy due to Disc Herniation: A Randomized Clinical Trial. To investigate the effects of the inclusion of neural mobilization into a motor control exercise program on pain, related-disability, neuropathic symptoms, straight leg raise (SLR), and pressure pain threshold (PPT) in lumbar radiculopathy.A randomized clinical trial.Individuals with LBP, with confirmed disc herniation, and lumbar (...) group experienced better improvements in neuropathic symptoms and the SLR compared to the motor control exercise group (P<0.01).The addition of neurodynamic mobilization to a motor control exercise program leads to reductions in neuropathic symptoms and mechanical sensitivity (SLR), but did not result in greater changes of pain, related-disability, or PPT over motor control exercises program alone in subjects with lumbar radiculopathy. Future trials are needed to further confirm these findings since

2019 American journal of physical medicine & rehabilitation Controlled trial quality: uncertain

14. Therapeutic effect of percutaneous endoscopic lumbar discectomy on lumbar disc herniation and its effect on oxidative stress in patients with lumbar disc herniation Full Text available with Trip Pro

Therapeutic effect of percutaneous endoscopic lumbar discectomy on lumbar disc herniation and its effect on oxidative stress in patients with lumbar disc herniation This study investigated the therapeutic effect of percutaneous endoscopic lumbar discectomy on lumbar disc herniation, and explored its effect on oxidative stress in patients with lumbar disc herniation. One hundred and ten patients with lumbar disc herniation were selected in The Affiliated People's Hospital of Shanxi Medical (...) and oxidative stress indicators MDA, MPO, SOD and TAC between the two groups before surgery (P>0.05). Levels of serum inflammatory factors TNF-α and CRP and oxidative stress indicators MDA and MPO were significantly lower and levels of oxidative stress indicators SOD and TAC were significantly higher in observation group than in control group (P<0.05). Therefore, treatment of lumbar disc herniation with percutaneous endoscopic lumbar discectomy has the advantages of small trauma, less blood loss and fast

2017 Experimental and therapeutic medicine Controlled trial quality: uncertain

15. Regression of lumbar disc herniation by physiotherapy. Does non-surgical spinal decompression therapy make a difference? Double-blind randomized controlled trial. (Abstract)

Regression of lumbar disc herniation by physiotherapy. Does non-surgical spinal decompression therapy make a difference? Double-blind randomized controlled trial. The aim of the study determining whether or not Non-invasive Spinal Decompression Therapy (NSDT) was effective in resorption of herniation, increasing disc height in patients with lumbar disc herniation (LHNP).A total of twenty patients diagnosed as LHNP and suffering from pain at least 8 weeks were enrolled to the study. Patients (...) therapy.Both treatments had positive effect for improving pain, functional restoration and reduction in thickness of herniation. Although reduction of herniation size was higher in SG than CG, no significant differences were found between groups and any superiority to each other (p> 0.05).This study showed that patients with LHNP received physiotherapy had improvement based on clinical and radiologic evidence. NSDT can be used as assistive agent for other physiotherapy methods in treatment of lumbar disc

2018 Journal of back and musculoskeletal rehabilitation Controlled trial quality: uncertain

16. Nocardial spinal epidural abscess with lumbar disc herniation: A case report and review of literature. Full Text available with Trip Pro

Nocardial spinal epidural abscess with lumbar disc herniation: A case report and review of literature. Nocardial spinal epidural abscess is rare. The diagnosis is often difficult to make and, if delayed, poses a high risk of long-term disability. Nocardial spinal epidural abscess with severe lumbar disc herniation has not previously been reported.A 50-year-old man presented with progressive lumbago and leg pain for 6 weeks after receiving acupuncture therapy, and then the patient suddenly (...) occurred urine retention after walking.Clinical examination revealed sign of cauda equina syndrome. Magnetic resonance imaging (MRI) revealed a Lumbar(L)4 to L5 disc herniation, L3 to Sacrum(S)1 epidural abscess, and L2 to S1 paravertebral abscess. The causative organism was Nocardia farcinica.An urgent paravertebral abscess debridement and right L4 to L5 laminectomy were performed. Simultaneously, the disc tissue protruding into the spinal canal was removed, as well as irrigation and drainage

2018 Medicine

17. Transforaminal epidural steroid injection combined with pulsed radio frequency on spinal nerve root for the treatment of lumbar disc herniation Full Text available with Trip Pro

Transforaminal epidural steroid injection combined with pulsed radio frequency on spinal nerve root for the treatment of lumbar disc herniation Lumbar disc herniation (LDH) is a common disease in clinical practice. The symptoms recur and are aggravated by time; severe pain and long-term movement disorder cause physiological and psychological problems that affect the quality of life of patients. Therefore, relieving the pain symptoms and promoting functional recovery are the primary goals (...) that have gained increased attention.To assess the efficacy of CT-guided transforaminal epidural steroid injection (TFESI) combined with pulsed radio frequency (PRF) on spinal nerve root for the treatment of LDH.Retrospective comparative study.Shengjing Hospital of China Medical University.A total of 135 patients with LDH were selected from the Department of Pain Management in the Shengjing Hospital of China Medical University between January 2014 and December 2016. All patients were divided into three

2018 Journal of pain research

18. Spinal manipulation in the treatment of patients with MRI-confirmed lumbar disc herniation and sacroiliac joint hypomobility: a quasi-experimental study Full Text available with Trip Pro

sequestrated disc herniation were excluded. All patients received five sessions of spinal manipulative therapy (SMT) for the SIJ and lumbar spine during a 2-week period. Back and leg pain intensity and functional disability level were measured with a numerical rating scale (NRS) and the Oswestry Disability Index (ODI) at baseline, immediately after the 5th session, and 1 month after baseline.A significantly greater mean improvement in back and leg pain was observed in the 5th sessions and 1 month after SMT (...) Spinal manipulation in the treatment of patients with MRI-confirmed lumbar disc herniation and sacroiliac joint hypomobility: a quasi-experimental study To investigate the effect of lumbar and sacroiliac joint (SIJ) manipulation on pain and functional disability in patients with lumbar disc herniation (LDH) concomitant with SIJ hypomobility.Twenty patients aged between 20 and 50 years with MRI-confirmed LDH who also had SIJ hypomobility participated in the trial in 2010. Patients who had

2018 Chiropractic & manual therapies

19. Lumbar spinal canal MRI diameter is smaller in herniated disc cauda equina syndrome patients. Full Text available with Trip Pro

Lumbar spinal canal MRI diameter is smaller in herniated disc cauda equina syndrome patients. Correlation between magnetic resonance imaging (MRI) and clinical features in cauda equina syndrome (CES) is unknown; nor is known whether there are differences in MRI spinal canal size between lumbar herniated disc patients with CES versus lumbar herniated discs patients without CES, operated for sciatica. The aims of this study are 1) evaluating the association of MRI features with clinical (...) presentation and outcome of CES and 2) comparing lumbar spinal canal diameters of lumbar herniated disc patients with CES versus lumbar herniated disc patients without CES, operated because of sciatica.MRIs of CES patients were assessed for the following features: level of disc lesion, type (uni- or bilateral) and severity of caudal compression. Pre- and postoperative clinical features (micturition dysfunction, defecation dysfunction, altered sensation of the saddle area) were retrieved from the medical

2017 PLoS ONE

20. Temporal and Spatial Changes of μ-Opioid Receptors in the Brain, Spinal Cord and Dorsal Root Ganglion in a Rat Lumbar Disc Herniation Model. Full Text available with Trip Pro

Temporal and Spatial Changes of μ-Opioid Receptors in the Brain, Spinal Cord and Dorsal Root Ganglion in a Rat Lumbar Disc Herniation Model. Controlled, interventional, animal study.To investigate the spatial and temporal changes of μ-opioid receptor (MOR) expression in a rat lumbar disc herniation (LDH) model.MORs widely express in the peripheral and central nervous systems, and opioid drugs produce an analgesic effect through their activation. However, the efficacy of opioid drugs (...) is sometimes inadequate in several pathological conditions of pain. MORs in the brain as well as the spinal cord (SC) and dorsal root ganglion (DRG) are thought to be associated with pain-related behavior, but the underlying mechanisms are not completely understood.In all, 91 adult female Sprague-Dawley rats were used. Autologous nucleus pulposus (NP) was applied onto the left L5 DRG in the NP group rats. Rats were divided into two surgical groups, the NP and the sham group. The von Frey test of left hind

2018 Spine

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