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Log Roll Test

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701. Patient Motion and Targeting Accuracy in Robotic Spinal Radiosurgery: 260 Single-Fraction Fiducial-Free Cases. (Abstract)

Patient Motion and Targeting Accuracy in Robotic Spinal Radiosurgery: 260 Single-Fraction Fiducial-Free Cases. To evaluate clinical targeting precision and assess patient movement data during fiducial-free, single-fraction spinal radiosurgery with the Cyberknife (CK).Image-guided spine tracking accuracy was tested using two phantoms. Movement patterns (three translations, roll, pitch and yaw) were obtained from log files of 260 patient treatments (47 cervical, 89 thoracic, 90 lumbar, and 34 (...) ± 0.20° (roll), 0.20 ± 0.08° (pitch), and 0.19 ± 0.08° (yaw). Spine region had little influence on overall targeting error, which was <1 mm for more than 95% of treatments (median, 0.48 mm). In the maximum motion case, target coverage decreased by 1.7% (from 92.1% to 90.4%) for the 20-Gy prescription isodose. Spinal cord volume receiving more than 8 Gy increased slightly, from 2.41 to 2.46 cm(3).Submillimeter targeting precision was obtained for fiducial-free spinal radiosurgery despite patient

2010 Biology and Physics

702. Two years survival rate of Class II ART restorations in primary molars using two ways to avoid saliva contamination. (Abstract)

restoration made using cotton rolls and experimental group using rubber dam. The restorations were evaluated by eight calibrated evaluators (Kappa > 0.8) after 6, 12, 18 and 24 months.A total of 48 (20.7%) children were considered dropout, after 24 months. The cumulative survival rate after 6, 12, 18 and 24 months was 61.4%, 39.0%, 29.1% and 18.0%, respectively for the control group, and 64.1%, 55.1%, 40.1% and 32.1%, respectively for the rubber dam group. The log rank test for censored data showed (...) Two years survival rate of Class II ART restorations in primary molars using two ways to avoid saliva contamination. To compare the survival rates of Class II Atraumatic Restorative Treatment (ART) restorations placed in primary molars using cotton rolls or rubber dam as isolation methods.A total of 232 children, 6-7 years old, both genders, were selected having one primary molar with proximal dentine lesion. The children were randomly assigned into two groups: control group with Class II ART

2010 International Journal of Paediatric Dentistry Controlled trial quality: uncertain

703. Effectiveness of Cervical Spine Stabilization Techniques. (Abstract)

Effectiveness of Cervical Spine Stabilization Techniques. To compare head motions that occur when trained professionals perform the head squeeze (HS) and trap squeeze (TS) C-spine stabilization techniques.Cross-over design.Twelve experienced lead rescuers.Peak head motion with respect to initial conditions using inertial measurement units attached to the forehead and trunk of the simulated patient. We compared both HS and TS during lift-and-slide (L&S) and log-roll (LR) placement on spinal (...) board, and agitated patient trying to sit up (AGIT-Sit) or rotate his head (AGIT-Rot). The a priori minimal important difference (MID) was 5 degrees for flexion or extension and 3 degrees for rotation or lateral flexion.The L&S technique was statistically superior to the LR technique. The only differences to exceed the MID were extension and rotation during LR (HS > TS). In the AGIT-Sit test scenario, differences in motion exceeded MID (HS > TS) for flexion, rotation, and lateral flexion

2011 Clinical Journal of Sport Medicine

704. Active Video Games and Sustainable Physical Activity

Baranowski, Baylor College of Medicine Study Details Study Description Go to Brief Summary: The purpose of this study is to test the effect of active video game play on physical activity of 9-13 year old children in their natural home environments. We observe how much physical activity children engage in after receiving two different active Wii video games and for how long they play. Active video games offer promise of minimizing children's physical inactivity. Condition or disease Intervention/treatment (...) the week prior to the introduction of the video game (baseline) and on weeks 1, 6, 7, and 12. They will keep a log of video game play on weeks 1, 6, 7 and 12. Objective video game play time will be transcribed at the end of week 12 from calendar stored in the Wii console. Height, weight, waist circumference, triceps skinfold will be measured prior to beginning study (baseline), and weeks 6 and 12. Questionnaires designed to examine the motivation to play a video game (end of weeks 6 and 12) and brief

2009 Clinical Trials

705. Computerized Counseling to Promote Positive Prevention and HIV Health in Kenya

and beliefs about computer use. Modify intervention content; translate and record audio into local Kiswahili. Adapt skill-building videos (e.g., on secondary prevention, HIV disclosure, ART adherence, reproductive health). Conduct software usability testing with n=20 patients and n=8 staff. Perform 3-day test-retest reliability assessment to establish psychometric performance of measures. Aim 2: Establish biological and behavioral efficacy of CARE+_Kenya. Longitudinal randomized controlled trial (RCT (...) system. This is directly responsive to PA-08-107's call for innovative, integrated interventions that leverage ART roll-out infrastructure in international settings to benefit people living with HIV. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 236 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Masking Description: The CARE Kenya counseling tool software randomizes

2009 Clinical Trials

706. Cervical Spine Motion Generated With Manual Versus Jackson Table Turning Methods in a Cadaveric C1-C2 Global Instability Model. (Abstract)

, no study has evaluated the effect of patient transfer methods from supine to prone position in the operating room, on atlantoaxial cervical spine motion. METHODS.: A global instability was surgically created at the C1-C2 level in 4 fresh cadavers. Two transfer protocols were tested on each cadaver. The log-roll technique entailed performing a standard 180 degrees log-roll rotation of the supine patient from a stretcher to the prone position onto the operating room Jackson table (OSI, Union City, CA (...) and translational motion. RESULTS.: For 6 of 6 measures of angulation and translation, manual log-roll prone positioning generated significantly more C1-C2 motion than the Jackson table turning technique. Out of 6 motion parameters, 5 were statistically significant (P < 0.001-0.005). There was minimal difference in C1-C2 motion generated when comparing all 3 head holding devices. CONCLUSION.: The data demonstrate that manual log-roll technique generated significantly more C1-C2 motion compared to the Jackson

2009 Spine

707. Comparing cervical spine motion with different halo devices in a cadaveric cervical instability model. (Abstract)

of sitting up. This testing sequence was followed for all treatment conditions.During the application of the orthoses there was a significant increase in motion at C1-C2 instability and a trend toward increased motion at the C5-C6 instability with CH compared with NIH. In the log roll maneuver, the CH and NIH restrict motion to a similar degree at the C1-C2 instability level, except in frontal plane translation, where CH immobilizes the segment to a greater extent. For the C5-C6 instability the CH (...) related to pin sites have been reported. The NIH was designed to overcome these complications. To date, no investigation has compared the biomechanical efficacy of the NIH with that of the CH in restricting three-dimensional cervical spine motion.A global instability was created at the C1-C2 level in 4 cadavers and at C5-C6 in 4 others. Relative motion was measured between the superior and inferior vertebrae during the donning process, execution of the log roll technique, and during the process

2009 Spine

709. Baraclude (entecavir)

process F, process A and B used different reagents, solvents and intermediates, while process C used the same sequence and the same intermediates but with some minor difference regarding the reagents and the working procedures. No significant differences between lots obtained by the different processes have been noted, especially in term of impurity profile. • Specification The active substance specification includes tests for appearance, colour, identity (IR, HPLC), optical rotation, assay (HPLC (...) ), impurities (HPLC) and water content. The HPLC method used to control the impurities allows detection of the diastereomeric impurities that may be present in the active. Concerning the enantiomeric purity of entecavir as well as residual solvents, heavy metals and sulphated ash, it has been found acceptable not to test them based on the justifications and data provided. Impurity limits in the specification are justified by toxicology studies. 3/55 ©EMEA 2006 Batch analysis data provided confirm

2007 European Medicines Agency - EPARs

710. Aptivus (tipranavir)

/10 (70.0) From the combined RESIST studies, the baseline genotypic testing demonstrated that the most common key codon mutation pattern observed in patients in the two arms were: • 82 and 90, n=252; • 84 and 90, n=209; • 84 only, n=184; • 33 and 82, n=170; • 90 only, n=97. The baseline combination of 82 and 84 was observed in 62 patients. 19/37 ? EMEA 2005 Looking at the primary endpoint treatment response (confirmed 1 log drop in viral load from baseline) for a variety of patterns in baseline (...) /200 TPV/r 750/200 All TPV/r Type of Analysis N Median N Median N Median ? 2 (p-value) a LOCF 73 -0.85 b 72 -0.93 b 71 -1.18 b 2.913 (0.2330) OT 70 -0.87 b 68 -0.96 b 66 -1.19 b 2.863 (0.2389) a Chi-square statistic and significance value from the Kruskal-Wallis test with 2 df. b p 1 log 10 reduction from baseline and the proportion of patients with viral load 1 000 copies/ml at screening, any CD4+ cell count). An amendment was made to the protocol to allow with highly protease inhibitor resistant

2005 European Medicines Agency - EPARs

711. Tobacco Use in the Perinatal Period

and educate regarding infant health as it relates to exposure to second hand smoke. Exclusive breastfeeding for the first six months of the infant’s life followed by the addition of nutrient-rich foods with continued breastfeeding for up to two years and beyond is also recommended. British Columbians can log on to a free website or phone a toll-free number to receive expert, individualized services that will help them quit smoking. • http://www.quitnow.ca ? is an Internet-based quit smoking service (...) ):1107 Mar 15 2002 www.aafp.org/afp. 1 British Columbia Reproductive Care Program 4. ASSESS Assess the woman’s: • level of tobacco addiction • readiness to quit • knowledge of smoking, health, and pregnancy 4. .1 Assess the woman’s level of tobacco addiction A smoker’s level of tobacco addiction is a major factor in determining how difficult it will be for her to stop smoking. The Abbreviated Fagerstrom Test for nicotine dependence shown in Table 3 is one of the screens for tobacco addiction

2006 British Columbia Perinatal Health Program

712. School Feeding for Improving the Physical and Psychosocial Health of Disadvantaged Students Full Text available with Trip Pro

, and haemoglobin, and hematocrit). Both hemoglobin and hematocrit are indices of anaemia, a condition in which the blood cannot carry enough oxygen, and most often due to iron deficiency. Psychological health outcomes included educational outcomes (e.g., school achievement in math, reading, or spelling, school enrolment, school attendance) and other tests of cognition such as intelligence test scores, psychomotor and mental development, attention, memory, reasoning, verbal fluency, vocabulary, on‐task (...) ) review group ( ). They were modified to capture specific items of data needed for this review. These forms were pilot‐tested with four included studies to ensure clarity, completeness and ease of use. Data were extracted by one of four reviewers and checked by another reviewer who had not done the original extraction. We extracted data on study design, description of the intervention (including process), details on participants (including age, sex, number in each group), length of intervention

2006 Campbell Collaboration

713. Work Programmes for Welfare Recipients Full Text available with Trip Pro

performed a Chi‐square test for heterogeneity. If this approached statistical significance (p < 0.10), we looked at the results of an I‐Squared test. If this was greater than 25%, we concluded that there was heterogeneity in the results. Addressing heterogeneity When heterogeneity was judged to be large, we examined potential sources using meta‐regression, and stratified analyses using categorical moderators. We performed meta‐regressions with the following intervention and contextual moderators (...) , Jobcentre Plus randomly assigned over 16,000 people, making the ERA evaluation the largest random assignment test of a social policy's effectiveness in the UK to date. Studies awaiting assessment According to Vasiliy V. Vlassov, director of the Russian branch of the Nordic Cochrane Centre (personal communication, 24 January, 2006), there are a number of Russian databases with free internet access where trials may be described. (A list of databases is at .) We have not been able to access them because

2006 Campbell Collaboration

714. A systematic review of the evidence for incentive schemes to encourage positive health and other social behaviours in young people

with other systematic review evidence. We found no evidence that single or dual component incentive schemes are effective in improving either the levels of effort applied to educational tests or attendance levels in school. Overall single or dual component incentive schemes do not appear to offer policy- makers or practitioners a simple route to ensuring general positive behaviour changes in young people. However, they may be useful in particular settings and for particular groups. Process evaluations (...) that the behaviour change required is achievable. The required behaviours need to be logged and rewarded consistently, and interventions designed to foster the required behaviour need to be implemented properly and consistently. Large- scale incentive-based schemes in particular require staff with the necessary skills and commitment to supporting young people through a scheme, and in turn such schemes require sound systems in place to support them. Consideration should be given to ensuring that the size or type

2006 EPPI Centre

715. Treatment and recommendations for homeless people with asthma

of Contents Summary of Recommendations v Introduction 1 ADULT ASTHMA Case Study: Homeless Adult with Asthma 3 Diagnosis and Evaluation History 4 Physical examination 5 Diagnostic tests 6 Plan and Management Education, self-management 7 Medications 8 Associated problems/complications 9 Follow-up 10 PEDIATRIC ASTHMA Case Study: Homeless Child with Asthma 11 Diagnosis and Evaluation History 12 Physical examination 13 Diagnostic tests 13 Plan and Management Education, self-management 14 Medications 15 (...) for cognitive deficits, delusions, hallucinations, and signs and symptoms of psychoactive substance use that complicate treatment adherence. Diagnostic tests • Spirometry – Access to spirometry may be limited; history, physical examination, and peak flow measurement may be the only available options for diagnosis. • Tuberculin testing and chest X-ray – Maintain a high index of suspicion for tuberculosis as an alternative or co-existing condition. Screen for tuberculosis with purified protein derivative

2008 National Health Care for the Homeless Council

716. Evaluation of the Uptake of Advice, Directives and Guidelines to the NHS Concerning Patient Safety by the SABS System

of clarity re responsibility. Usually part of planned maintenance programme Implantable cardioverter defibrillators (ICDs) 5 Problems for trusts in assessing impact. Well implemented following assessment. Reduction of harm caused by misplaced nasogastric feeding tubes 7 Acute trusts reported confidence in implementation. Variable awareness at ward level. Confusion with pH testing. Alcohol based hand rub 1 Dispensers across hospitals. Some problems with location. Not seen as high risk Universal hospital (...) . The Department of Health Report, Building a safer NHS for patients (Department of Health 2001) detailed the implementation of the earlier report. Six key steps, inter alia, were identified: • Establishing agreed definitions of adverse events and near misses for the logging and reporting within the NHS, with the issuing of detailed guidance; • Formalising a minimum data set; • Producing a standardised format of reporting; • Building expertise within the NHS in root cause analysis; • Ensuring that information

2007 York Health Economics Consortium

717. Neurological examination identified 61% of patients with focal cerebral hemisphere lesions but without obvious focal signs Full Text available with Trip Pro

{used clinical judgement}* to conclude whether or not there was a focal lesion and, if so, which side was affected. The examiner was blind to the imaging results and the clinical history. Diagnostic standard: computed tomography and/or magnetic resonance imaging performed before study entry. Outcomes: sensitivity, specificity, and positive and negative likelihood ratios. MAIN RESULTS Only 4 of the individual tests had sensitivity >25%: finger rolling (33%, 95% CI 21 to 47), upper motor neurone (...) this and improve the sensitivity in several ways: taking a careful history (the most important), combining multiple examination elements (diagnostic tests in parallel), and using other diagnostic tests (eg, neuroimaging). Secondly, this study highlights the potential usefulness of the forearm or finger-rolling test to uncover subtle upper motor neurone weakness. These tests are not taught routinely as part of the neurological examination, yet they performed as well as, and possibly better than, pronator drift

2006 Evidence-Based Medicine

718. Administration of Intravenous Radiopharmaceuticals

techniques 14 Frusemide 14 Lymphoscintigram 14 Inserting a Cannula 14 MIBG I123 15 Transplant Renogram 15 Paediatric Injections 15 BIBLIOGRAPHY 15 Page 3 of 30 FURTHER READING 16 APPENDIX 1: LOG SHEETS 17 Page 4 of 30 Executive Summary This document been produced by representatives from the BNMS Technology group and the Nurses group. It was instigated by the Professional Standards and Education committee, who saw the need for a transferable record of practical experience for non- medical staff performing (...) there may be a higher risk of thrombophlebitis Mobile – likely to roll if not adequately secured LEGAL GUIDELINES Every person is legally owed a legal duty of care (Donaghue V Stevenson 1932). In addition the Nursing and Midwifery Council Code of Professional Conduct should be observed, particularly points 1-6. In short the practitioner must: 1. Act in a manner to safeguard the well being of the patient. 2. Ensure that no act or omission on the practitioner’s part is detrimental to the patient. 3

2006 British Nuclear Medicine Society

719. Results of the economic evaluation of the FIRST study: a multinational prospective economic evaluation

for epoprostenol therapy at the time of writing. Costs of concomitant medications were also excluded. Statistical analysis of costs 95% confidence intervals (CI) were generated around the projection of expected costs and QALMs had all patients been followed for 12 months using the nonparametric bootstrap procedure. Due to the potentially skewed nature of costs, an additional analysis to test for differences was performed on the log of total costs. Indirect Costs Not stated. Currency US dollars ($). Sensitivity (...) of whom 239 (51%) received epoprostenol/usual care and 232 (49%) received usual care alone. The two groups were similar except for the proportion of patients receiving assistance in daily living from someone other than a friend or home health aide. Study design This was a multinational randomised controlled trial. The enrolment into the trial was on a rolling admission basis, hence the patients' follow-up time ranged from a few weeks to 18 months. In total, data for 1,932 patient months were collected

1996 NHS Economic Evaluation Database.

720. Boceprevir (SCH 503034) Plus Peg-Intron, With and Without Added Ribavirin, in Patients With Chronic Hepatitis C, Genotype 1, Who Did Not Respond to Previous Treatment With Peginterferon Alfa Plus Ribavirin (Study P03659AM2)(COMPLETED)

: Baseline up to dosing change (> 25 weeks) ] Change in ALT levels during initial treatment regimen and after rolling into amendment 2 as compared to baseline. Number of Participants Who Were HCV-RNA Negative During Amendment 2 (AM2) for Those Who Started on Arms 2 (PEG+BOC 100), 3 (PEG+BOC 200), 4 (PEG+BOC 400 [48 Weeks]), 6 (PEG+BOC 400 [24 Weeks]) [ Time Frame: From dosing change to end of follow-up (Week 73)(up to 48 weeks) ] Log drop at baseline of dosing change = difference of log viral loads (...) is detectable, BOC 400 mg TID will be added for 36 weeks. By second protocol amendment to P03659, participants will be rolled over into Arm 8 for the remainder of the treatment period. Drug: Boceprevir (BOC) 100 or 200 mg capusles taken orally as 100 mg, 200 mg, 400 mg, or 800 mg TID Other Name: SCH 503034 Biological: PegIntron (PEG) 1.5 mcg/kg weekly subcutaneously Drug: Ribavirin (RBV) 200 mg capsules taken twice daily (BID) (total daily dose of 800-1400 mg/day, depending on weight [weight-based dosing

2005 Clinical Trials

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