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41. Review of information management practices in the HSE Computerised Infectious Disease Reporting (CIDR) system

to ensure a high-quality safe service. Safe, reliable healthcare depends on access to, and the use of, information that is accurate, valid, reliable, timely, relevant, legible and complete. For example, when giving a patient a drug, a nurse needs to be sure that they are administering the appropriate dose of the correct drug to the right patient and that the patient is not allergic to it. Similarly, lack of up- to-date information can lead to the unnecessary duplication of tests — if critical diagnostic (...) results are missing or overlooked, tests have to be repeated unnecessarily and, at best, appropriate treatment is delayed or at worst not given. In addition, health information has an important role to play in healthcare planning decisions — where to locate a new service, whether or not to introduce a new national screening programme and decisions on best value for money in health and social care provision. Under Section (8)(1)(k) of the Health Act 2007, the Health Information and Quality Authority

2019 HIQA Health Information

42. Achieving Health Equity in Preventive Services

of randomized controlled trials of the overall effect of patient navigation on colorectal cancer screening rates 103 Figure 6. Meta-analysis of randomized controlled trials of the effect of patient navigation on colorectal cancer screening rates by screening test, where subgroup results include all relevant studies 104 Figure 7. Meta-analysis of randomized controlled trials of the effect of patient navigation on colorectal cancer screening rates by screening adherence at baseline 105 Figure 8. Meta-analysis (...) of randomized controlled trials of the effect of patient navigation on colorectal cancer screening rates by followup time 106 Figure 9. Meta-analysis of randomized controlled trials of the effect of patient navigation on colorectal cancer screening rates by study quality 107 Figure 10. Meta-analysis of observational studies of the effect of patient navigation on colorectal cancer screening rates by screening test 108 xi Figure 11. Meta-analysis of randomized controlled trials of the effect of patient

2019 Effective Health Care Program (AHRQ)

43. Innovation to Create a Healthy and Sustainable Food System: A Science Advisory From the American Heart Association Full Text available with Trip Pro

Innovation to Create a Healthy and Sustainable Food System: A Science Advisory From the American Heart Association Innovation to Create a Healthy and Sustainable Food System: A Science Advisory From the American Heart Association | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search June 2019 June 2019 June 2019 May 2019 May 2019 May 2019 May 2019 April 2019 April 2019 April 2019 April 2019 April 2019 March 2019 March 2019 March 2019 March 2019 March (...) Small increases in healthier purchases , Online shopping strategies to promote healthier purchases Potential to increase healthier food purchases, but research is limited Restaurants Menu labeling Increases healthier food choices Restrictions on children’s meals with toys May reduce children’s intake of calories, sodium, and fat , Healthy default choices (eg, no SSBs in children’s meals, smaller portion sizes, whole grain rather than refined grains in breads/rolls) Potential to reduce intake

2019 American Heart Association

44. Practice Advisory for Perioperative Visual Loss Associated with Spine Surgery 2019 Full Text available with Trip Pro

Practice Advisory for Perioperative Visual Loss Associated with Spine Surgery 2019 Practice Advisory for Perioperative Visual Loss Associated with Spine Surgery 2019:An Updated Report by the American Society of Anesthesiologists Task Force on Perioperative Visual Loss, the North American Neuro-Ophthalmology Society, and the Society for Neuroscience in Anesthesiology and Critical Care* | Anesthesiology | ASA Publications 1655814791 ASA Publications Log in to access full content You must (...) be logged in to access this feature. ASA members enjoy complimentary access to ASA publications, as well as a variety of educational resources. Non-ASA Members Login Free Practice Parameter | January 2019 Practice Advisory for Perioperative Visual Loss Associated with Spine Surgery 2019: An Updated Report by the American Society of Anesthesiologists Task Force on Perioperative Visual Loss, the North American Neuro-Ophthalmology Society, and the Society for Neuroscience in Anesthesiology and Critical

2019 American Society of Anesthesiologists

45. Heart Disease and Stroke Statistics Full Text available with Trip Pro

Heart Disease and Stroke Statistics Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search March 2019 March 2019 March 2019 February 2019 February 2019 February 2019 February 2019 January 2019 January 2019 January 2019 January 2019 January 2019 This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies. Free Access article

2019 American Heart Association

47. WHO Guideline: recommendations on digital interventions for health system strengthening

in technology. From the development of modern sanitation to the advent of penicillin, anesthesia, vaccines and magnetic resonance imaging, science, research and technology have always been key drivers of better health. It’s no different today. Advances in technology are continuing to push back the boundaries of disease. Digital technologies enable us to test for diabetes, HIV and malaria on the spot, instead of sending samples off to a laboratory. 3-D printing is revolutionizing the manufacture of medical (...) of digital technologies for health […] and to prioritize, as appropriate, the development, evaluation, implementation, scale-up and greater use of digital technologies,... Furthermore, it tasked WHO with providing normative guidance in digital health, including through the promotion of evidence- based digital health interventions. Amid the heightened interest, digital health has also been characterized by implementations rolled out in the absence of a careful examination of the evidence base on benefits

2019 World Health Organisation Guidelines

48. Measurement of Blood Pressure in Humans Full Text available with Trip Pro

Measurement of Blood Pressure in Humans Measurement of Blood Pressure in Humans: A Scientific Statement From the American Heart Association | Hypertension Search Hello Guest! Login to your account Email Password Keep me logged in Search May 2019 April 2019 March 2019 February 2019 January 2019 This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies. Free Access article Share on Jump to Free Access article Measurement of Blood Pressure in Humans (...) in Selecting Cuff Sizes for BP Measurement Arm circumference should be measured at the midpoint of the acromion and olecranon. BP cuff bladder length should be 75%–100% of the patient’s measured arm circumference. BP cuff bladder width should be at 37%–50% of the patient’s arm circumference (a length-to-width ratio of 2:1) BP cuff should be placed on bare skin. Shirtsleeves should not be rolled up because this may create a tourniquet effect. The most frequent error in measuring office BP is “miscuffing

2019 American Heart Association

49. Sexual offender treatment for reducing recidivism among convicted sex offenders: a systematic review and meta?analysis Full Text available with Trip Pro

control groups were included if the design allowed testing of a program effect (see outcome measures). 4. Measure of recidivism as outcome. An indication of officially registered new offences had to be included as a dependent variable. Although recidivism is not a very sensitive indicator of treatment effects (e.g. ), it is politically and practically most relevant. We followed a broad definition of recidivism (sexual as well as non‐sexual offences). Studies could use criteria such as arrest, charge (...) of the simple recidivism rates. In logistic regression, the coefficients equal the natural log of the OR ( LOR ), and as an exponent to e this equals the OR (see ). The result for the treatment variable could thus be transferred directly. In Cox regression, results are reported in the form of a risk ratio, which is similar but not identical to the OR . We used the risk ratio ( RR ) to estimate a recidivism rate for the CG corrected for the group differences considered in the Cox regression model ( p CG = RR

2017 Campbell Collaboration

50. The effectiveness of contract farming for raising income of smallholder farmers in low? and middle?income countries: a systematic review Full Text available with Trip Pro

instance with a statistically significant positive income effect. Test results suggested that studies with non‐significant effects of contract farming are likely to exist but are not reported in the academic literature. Studies also suffer from survivor bias. All studies are cross‐sectional studies that assess the effectiveness of the contractual arrangement at one moment in time, but only after the contractual arrangements had been in place for some years when these had already survived the start‐up (...) ) is zero and therefore allows the estimation of equation with OLS. The implementation of a RCT for contract farming is rarely feasible. It would require a firm that accepts a research design for out‐rolling its contract offer. For instance, the firm could offer contracts in a predefined number of villages (the treatment group), while not offering it in neighbouring villages (the control group). Data could then be collected before the implementation of the contract in all villages (the baseline

2017 Campbell Collaboration

51. Cash?based approaches in humanitarian emergencies: a systematic review Full Text available with Trip Pro

the assumption that certain enabling conditions are required has not been robustly tested, a variety of tools and guidance documents are available to help organizations determine whether cash transfers are appropriate and how information to determine how to best operationalize a cash based response can be collected (CaLP, 2015). It should also be noted that the objectives of cash programmes are varied, and range from maintaining the status quo (such as household access to food in the context of a food (...) Public Health Information Specialist developed the search strategy after input from investigators on the research team. Results of the pilot search were reviewed by the research team and the strategy was developed iteratively. We also provided the information specialist with several key papers as a test set that was used to check to completeness of the search results. The search strategy included a combination of controlled vocabulary and keywords for cash and emergencies. Databases and basic search

2017 Campbell Collaboration

52. Emergency Medicine Early Warning System (EMEWS) In Pilot Sites

and assistance with the development of this guideline. Special thanks to the staff of the Emergency Departments in Connolly Hospital, Blanchardstown; Naas General Hospital; University Hospital, Waterford; University Hospital, Galway; Sligo University Hospital and St James’s Hospital who pilot tested the guideline at various stages during its development. Guideline developers note: The working title used during the development of this guideline was the Emergency Department Monitoring and Clinical Escalation (...) the development of this guideline 16 2.6.1 Development and testing of EMEWS – Overview of the initial development project 16 2.7 Clinical and financial impact of deterioration in EDs 18 2.8 Elements of EMEWS 20 2.8.1 Development and testing of EMEWS 20 2.8.2 The Manchester Triage System interface with EMEWS 20 2.8.3 Inclusion and exclusion criteria for the EMEWS 21 2.9 Post-Triage Emergency Nursing Review Process 22 2.9.1 Starting Post-Triage Emergency Nursing Review 22 2.9.2 Post-Triage Emergency Nursing

2018 National Clinical Guidelines (Ireland)

53. Multidisciplinary guidelines for the management of paediatric tracheostomy emergencies Full Text available with Trip Pro

differences in paediatric management. Early versions were discussed among the Working Party and our multidisciplinary colleagues, and were tested using high‐fidelity medical simulation at local bespoke meetings using faculty and volunteers. Key steps were designed to address contributing factors to poorly managed emergencies, which include lack of access to information or emergency algorithms, loss of situational awareness and poor communication , . We recognised the role that simulation could play (...) in further refining the algorithm key steps and have previously described testing versions of the algorithm in over 450 volunteer healthcare professional encounters at national and international meetings, where the algorithm was also formally presented . We were able to demonstrate significant improvements in performance metrics when multidisciplinary responders followed the algorithm in similar scenarios. Scenarios were completed more quickly, the simulated children were less hypoxic and more candidates

2018 Association of Paediatric Anaesthetists of Great Britain and Ireland

54. Approaches to promote handwashing and sanitation behaviour change in low? and middle?income countries: a mixed method systematic review Full Text available with Trip Pro

of the Social Sciences (IBSS, ProQuest) • MEDLINE (PubMed) • PsycINFO (EBSCOHost) • Social Sciences Citation Index (SSCI, Web of Science) • Sociological Abstracts (ProQuest) A sensitive search strategy based on existing search strategies from existing WASH systematic reviews, our ToC and our selection criteria, was developed by an information specialist and tested in an iterative way for each database separately. A combination of index terms (where relevant) and free text words (in title/abstract) was used

2017 Campbell Collaboration

55. Cladribine (Mavenclad) - multiple sclerosis

to be a known active substance. The application submitted is composed of administrative information, complete quality data, non-clinical and clinical data based on applicants’ own tests and studies and/or bibliographic literature substituting/supporting certain tests or studies. Information on Paediatric requirements Pursuant to Article 7 of Regulation (EC) No 1901/2006, the application included an EMA Decision(s) P/101/2009 on the granting of a product-specific waiver. Information relating to orphan market (...) 10/2011 as amended. Specification The active substance specification includes appropriate tests and limits for appearance (visual), identity (IR, Ph. Eur.), appearance of a solution (Ph. Eur.), pH of solution, specific rotation (Ph. Eur.), heavy metals, residue on ignition (Ph. Eur.), water content (Ph. Eur.), assay (Ph. Eur.), purity (HPLC, TLC, Ph. Eur.), residual solvents (GC), residual ammonia (ion chromatographic) and bacterial endotoxins (Ph. Eur.). The specification of the active substance

2017 European Medicines Agency - EPARs

56. Identifying and Assessing Core Components of Collaborative-care Models for Treating Mental and Physical Health Conditions

from Ontario found that individuals with schizophrenia and diabetes received diabetes care that was significantly sub-optimal compared with those without schizophrenia in relation to guideline-concordant testing for HbA1c, lipid testing and eye exams);(16) • overuse of some types of services (such as increased rates of intensive-care-unit admissions, ambulatory care, and emergency department visits);(14; 16) and • high risk of medical errors.(17) While there are a number of reasons for the delivery (...) -systematic reviews, 37 primary studies, and five program and system descriptions/analyses. Core principles of collaborative-care models The AIMS centre at the University of Washington in partnership with a group of U.S. experts have been at the forefront of research on collaborative-care models, which has included developing their own model of collaborative care, testing it, and supporting its implementation in different contexts. Since the centre’s initial work, it has identified five core principles

2017 McMaster Health Forum

57. Nusinersen sodium (Spinraza) - Spinal Muscular Atrophy

for this application refers to: Article 8.3 of Directive 2001/83/EC - complete and independent application. The applicant indicated that nusinersen was considered to be a new active substance. The application submitted is composed of administrative information, complete quality data, non- clinical and clinical data based on applicants’ own tests and studies and/or bibliographic literature substituting/supporting certain test(s) or study(ies). Information on Paediatric requirements Pursuant to Article 7 (...) toxicologically relevant exposure in the developing fetus. Nusinersen was non-genotoxic when tested in the bacterial reverse mutagenesis assay, in vitro chromosomal aberration assay in CHO cells and the in vivo mouse micronucleus assay. Therefore, nusinersen was interpreted to be neither mutagenic nor clastogenic. Carcinogenicity studies have not been conducted with nusinersen. Nusinersen is not genotoxic and does not have a direct mechanism for tumor induction. There is no reason to believe

2017 European Medicines Agency - EPARs

58. Darunavir / cobicistat / emtricitabine / tenofovir alafenamide (Symtuza) - HIV Infections

is therefore to suppress the HIV-1 viral load to levels that are at least below 50 copies/mL of blood. 2.1.4. Clinical presentation and diagnosis Acute HIV-1 infection is often missed, as it usually presents with nonspecific signs and symptoms, or goes without clinical symptoms. Diagnosis therefore most often occurs during chronic infection. Diagnostic tests for HIV-1 infection include assays for HIV-1 RNA, p24 antigen, and HIV-1 and HIV-2 antibodies. 2.1.5. Management Antiretroviral therapy (ART (...) with the requirements of Ph. Eur. and European Directive 10/2011 as amended. Assessment report EMA/496527/2017 Page 13/106 Specification Darunavir specification includes tests for identification (IR, UPLC), physical description (visual), assay (HPLC), chromatographic purity (HPLC), ethanol (GC), residual solvent (GC), residue on ignition (Ph. Eur.), water content (KF), heavy metals (Ph. Eur.) and particle size (laser diffraction). Specifications, analytical procedures and validation data are in accordance

2017 European Medicines Agency - EPARs

59. Naloxone (Nyxoid) - Opioid-Related Disorders

information regarding proof of structure studies and physicochemical characterisation has been assessed by the EDQM before issuing the Certificate of Suitability. Manufacture, characterisation and process controls The relevant information has been assessed by the EDQM before issuing the Certificate of Suitability. Specification The active substance specification includes tests for: appearance (visual), identity (IR), identity of chlorides (Ph. Eur.), appearance of solution (Ph. Eur.), acidity (...) or alkalinity (Ph. Eur.), specific optical rotation (Ph. Eur.), related substances (HPLC), water (Ph. Eur.), sulfated ash (Ph. Eur.), assay (Ph. Eur.) and residual solvents (GC). The analytical methods used have been adequately described and non-compendial methods appropriately validated in accordance with the ICH guidelines. Satisfactory information regarding the reference standards used for assay and impurities testing has been presented. The control tests were carried out to comply

2017 European Medicines Agency - EPARs

60. Out-of-Hospital Cardiac Arrest Resuscitation Systems of Care: A Scientific Statement From the American Heart Association

Out-of-Hospital Cardiac Arrest Resuscitation Systems of Care: A Scientific Statement From the American Heart Association Out-of-Hospital Cardiac Arrest Resuscitation Systems of Care: A Scientific Statement From the American Heart Association | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search March 2019 March 2019 March 2019 March 2019 March 2019 February 2019 February 2019 February 2019 February 2019 January 2019 January 2019 January 2019 January (...) centers continues to result in improved outcomes for patients with OHCA. In 2007, Arizona rolled out a statewide model of regionalizing postarrest care that included state-recognized cardiac receiving centers, implementation of postarrest care focused on therapeutic hypothermia, emergent coronary angiography, and delayed prognostication of neurological status, along with an EMS bypass protocol triaging comatose, postarrest patients with OHCA with ROSC to the closest recognized cardiac arrest center

2018 American Heart Association

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