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Localized Edema

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1. Localization of Muscle Edema and Changes on Muscle Contractility After Dry Needling of Latent Trigger Points in the Gastrocnemius Muscle. (PubMed)

Localization of Muscle Edema and Changes on Muscle Contractility After Dry Needling of Latent Trigger Points in the Gastrocnemius Muscle. Myofascial trigger points (TrPs) are hyperirritable spots within taut bands of skeletal muscles that elicit local and referred pain when stimulated. Among the variety of techniques used for treating TrPs, dry needling (DN) is the most commonly applied intervention. The physiological mechanisms underlying the effects of DN remain to be elucidated.To examine (...) of intramuscular edema. Tensiomyographic parameters showed higher muscle stiffness with an improvement in contraction time after DN.This is the first study showing intramuscular edema after TrP DN in human skeletal muscle. Future research should focus on using DN therapy in patients with active TrPs and on monitoring changes occurring at longer follow-up with imaging techniques.

2019 Pain Medicine

2. Which MR sequences should we use for the reliable detection and localization of bone marrow edema in spondyloarthritis? (PubMed)

Which MR sequences should we use for the reliable detection and localization of bone marrow edema in spondyloarthritis? To assess the diagnostic confidence in detecting and localizing areas of bone marrow edema in the sacroiliac joint of patients with suspected spondyloarthritis using a single-plane method and comparing it with multiplanar unenhanced and enhanced methods.Patients with clinical suspicion of spondyloarthritis undergoing an MRI of the sacroiliac joint were included (...) in this retrospective study. To assess sacroiliitis, three methods were applied: single-plane (i.e., para-coronal STIR alone), multiplanar unenhanced (i.e., para-coronal STIR and para-axial PD-fs), and multiplanar enhanced method (i.e., para-coronal and para-axial post-contrast T1-fs). Two 4-point scales were used to evaluate, respectively, the diagnostic confidence in detection and localization of bone marrow edema. The distribution of certain and uncertain rating according to signal intensity and size

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2017 La Radiologia medica

3. Neurogenic mediators contribute to local edema induced by Micrurus lemniscatus venom (PubMed)

Neurogenic mediators contribute to local edema induced by Micrurus lemniscatus venom Micrurus is one of the four snake genera of medical importance in Brazil. Coral snakes have a broad geographic distribution from the southern United States to Argentina. Micrurine envenomation is characterized by neurotoxic symptoms leading to dyspnea and death. Moreover, various local manifestations, including edema formation, have been described in patients bitten by different species of Micrurus. Thus, we (...) investigated the ability of Micrurus lemniscatus venom (MLV) to induce local edema. We also explored mechanisms underlying this effect, focusing on participation of neuropeptides and mast cells.Intraplantar injection of MLV (1-10 μg/paw) in rats caused dose- and time-dependent edema with a peak between 15 min and 1 h after injection. MLV also induced degranulation of peritoneal mast cells (MCs). MC depletion by compound 48/80 markedly reduced MLV-induced edema. Pre-treatment (30 min) of rats with either

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2017 PLoS neglected tropical diseases

4. Localized Edema

Localized Edema Localized Edema Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Localized Edema Localized Edema Aka: Localized Edema (...) VI. Causes: Lymphatic Obstruction Neoplasm Surgical excision VII. Causes: Local Trauma or injury or Ligamentous Sprain or tendonous strain Irritant or corrosive VIII. Causes: Congenital Amniotic band Arteriovenous fistula Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Localized Edema." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology

2018 FP Notebook

5. A Study to Evaluate the Effectiveness of Intravitreal Aflibercept in Patients With Diabetic Macular Edema and/or Macular Edema Secondary to Retinal Vein Occlusion, Which Either Have or Have Not Been Pretreated for Their Disease

) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Sampling Method: Probability Sample Study Population Female and male patients of legal age with a diagnosis of DME or macular edema following RVO will be enrolled in eye clinics and ophthalmology practices after the decision for treatment with aflibercept has been made by the treating physician. Criteria Inclusion Criteria: For DME -- Female and male patients of legal age, as defined by local regulations and local product labels (...) , with visual impairment due to DME For macular edema secondary to RVO -- Female and male patients of legal age, as defined by local regulations and local product labels, with visual impairment due to macular edema secondary to RVO Patient for whom the decision to initiate treatment with aflibercept is made prior to and independent from study participation Signed informed consent. Exclusion Criteria: Any contraindications as listed in the local intravitreal aflibercept SmPC (summary of product

2017 Clinical Trials

6. Is it melanoma-associated retinopathy or drug toxicity? Bilateral cystoid macular edema posing a diagnostic and therapeutic dilemma (PubMed)

Is it melanoma-associated retinopathy or drug toxicity? Bilateral cystoid macular edema posing a diagnostic and therapeutic dilemma To report the clinical presentation, multimodal imaging, and management of a patient with metastatic melanoma who presented with cystoid macular edema (CME).We report a case of a 71-year-old Caucasian male with metastatic melanoma who presented with bilateral cystoid macular edema after being on treatment with a programmed T cell death ligand 1 inhibitor, MPDL3280 (...) , for 1 year. Multimodal imaging techniques, including color fundus photographs, autofluorescence, spectral domain optical coherence tomography (OCT), fluorescein angiography (Spectralis, Heidelberg, Germany), and spectral-domain OCT angiography (Zeiss; California, USA) were performed to evaluate the etiology of his CME and to monitor his response to treatment. Clinical examination and multimodal imaging revealed 1 + chronic vitreous cells, an epiretinal membrane, and mild macular edema in both eyes

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2018 American journal of ophthalmology case reports

7. Fluid restriction reduces pulmonary edema in a model of acute lung injury in mechanically ventilated rats. (PubMed)

Fluid restriction reduces pulmonary edema in a model of acute lung injury in mechanically ventilated rats. Experimental acute lung injury models are often used to increase our knowledge on the acute respiratory distress syndrome (ARDS), however, existing animal models often do not take into account the impact of specific fluid strategies on the development of lung injury. In contrast, the current literature strongly suggests that fluid management strategies have a significant impact on clinical (...) these were unaffected by fluid strategy. Finally, we found significantly higher IL-1β and TNF-α concentrations in the adult rats treated with the conservative as compared to the standard fluid regimen. In conclusion, the choice of fluid strategy in mechanically ventilated rats with experimental LPS-induced acute lung injury has a significant effect on pulmonary extravascular water, an important and well-recognized lung injury marker, and on the local pro-inflammatory cytokine profiles. We advocate

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2019 PLoS ONE

8. Visual and Clinical Outcome of Macular Edema Complicating Pediatric Noninfectious Uveitis. (PubMed)

Visual and Clinical Outcome of Macular Edema Complicating Pediatric Noninfectious Uveitis. To investigate the clinical course and visual outcome of macular edema (ME) in pediatric patients with chronic noninfectious uveitis.Retrospective case series.The databases of the uveitis clinics of four tertiary medical centers in Israel and the UK were searched for all children treated for uveitic ME in 2005-2015. Data were collected from the medical records as follows: demographics, diagnosis, visual (...) months. Baseline visual acuity was ≥20/40 in 8 eyes (24.2%), increased to 57.6% at 3 months (P <0.0001), and remained stable thereafter. Treatment regimens included corticosteroids (systemically and/or locally), immunosuppression and biologic therapies. No correlation was found between outcome and either structural characteristics of ME or specific treatment strategy.The prognosis of pediatric uveitic ME is favorable despite its chronic course. Larger randomized controlled trials are needed to define

2019 American Journal of Ophthalmology

9. Comparison of Lower Extremity Edema in Locally Advanced Cervical Cancer: Pretreatment Laparoscopic Surgical Staging with Tailored Radiotherapy Versus Primary Radiotherapy. (PubMed)

Comparison of Lower Extremity Edema in Locally Advanced Cervical Cancer: Pretreatment Laparoscopic Surgical Staging with Tailored Radiotherapy Versus Primary Radiotherapy. This study investigated the clinical manifestations of lower extremity edema (LEE) in locally advanced cervical cancer patients treated with two different strategies.In total, 79 cervical cancer survivors with International Federation of Gynecology and Obstetrics stage IB2-IIB were included. Six survivors with stage IB1

2015 Annals of Surgical Oncology

10. Evaluation the Efficacy of Hilotherm Cooling System in Reducing Postoperative Pain and Edema in Maxillofacial Traumatized Patients and Orthognathic Surgeries. (PubMed)

Evaluation the Efficacy of Hilotherm Cooling System in Reducing Postoperative Pain and Edema in Maxillofacial Traumatized Patients and Orthognathic Surgeries. Surgical treatment in patients with facial bone surgeries governs a meaningful extent of tissue trauma prompting prevalent postoperative portents of pain, facial swelling, and inconvenience. Beneficial effects of local cold therapy following surgery, facial swelling, pain, and inflammation have been discussed. The aim of study (...) is to evaluate the efficacy of hilotherm cooling system in reducing postoperative pain and edema in patients following maxillofacial trauma and orthognathic surgeries.A clinical prospective study was done in the postoperative period for patients with facial trauma or those subjected to orthognathic surgery, 34 patients divided randomly into 2 groups; study group treated with the hilotherm cooling system and control group without. Facial swelling was quantified by 5 linear distances (A, B, C, D, and E). Pain

2018 The Journal of craniofacial surgery

11. Macular integrity assessment to determine the association between macular microstructure and functional parameters in diabetic macular edema (PubMed)

Macular integrity assessment to determine the association between macular microstructure and functional parameters in diabetic macular edema To respectively evaluate macular morphological features and functional parameters by using spectral-domain optical coherence tomography (SD-OCT) and macular integrity assessment (MAIA) in patients with diabetic macular edema (DME).This prospective, non-controlled, open study included 61 eyes of 38 consecutive patients with DME. All patients underwent best (...) ) and morphological parameters (retinal thickness) were significantly associated with an intact IS/OS. Local photoreceptor integrity was a strong predictor of local visual function throughout the retina. MI revealed the functional status in DME, reflecting the IS/OS juction status in the macula.

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2018 International journal of ophthalmology

12. Combination ipilimumab and radiosurgery for brain metastases: tumor, edema, and adverse radiation effects. (PubMed)

compared using the Kruskal-Wallis test. Local failure, lesion hemorrhage, and treatment-related imaging changes (TRICs) were analyzed with the Cox proportional hazards model.RESULTSOf 310 analyzed lesions, 91 were not treated with ipilimumab, 59 were treated with concurrent ipilimumab, and 160 were treated with nonconcurrent ipilimumab. Of 106 randomly selected lesions with measurable peritumoral edema, the mean edema volume by manual contouring was 7.45 cm3 and the mean volume by (length × width (...) = 0.01) and 6 months (p = 0.02). The concurrent ipilimumab group also had the highest rate of lesion hemorrhage (p = 0.01). Any ipilimumab was associated with higher incidence of symptomatic TRICs (p = 0.005). The overall incidence of pathologically confirmed radiation necrosis (RN) was 2%. In multivariate analysis, tumor and edema response at 3 months were the strongest predictors of local failure (HR 0.131 and HR 0.125) and lesion hemorrhage (HR 0.225 and HR 0.262). Tumor and edema response at 1.5

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2018 Journal of Neurosurgery

13. Natriuretic peptides system in the pulmonary tissue of rats with heart failure: potential involvement in lung edema and inflammation (PubMed)

Natriuretic peptides system in the pulmonary tissue of rats with heart failure: potential involvement in lung edema and inflammation Congestive heart failure (CHF) often leads to progressive cardiac hypertrophy and salt/water retention as evident by peripheral and lung edema. Although the pathogenesis of CHF remains largely unclarified, it is widely accepted that neurohormonal changes and inflammatory processes are profoundly involved in structural and functional deterioration of vital organs (...) of all experimental groups. However, the expression and abundance of pulmonary corin significantly increased in the decompensated animals, but not in the compensated ones. Noteworthy, the expression of PCSK6 and ANP/BNP in the pulmonary tissue followed a similar pattern as corin. The upregulation of pulmonary Corin/PCSK6 and NPs were accompanied by local activation of cathepsin L and certain cytokines including IL-6. In light of the anti-inflammatory role of NPs, we postulate that the obtained

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2018 Oncotarget

14. Follow up of MRI bone marrow edema in the treated diabetic Charcot foot – a review of patient charts (PubMed)

Follow up of MRI bone marrow edema in the treated diabetic Charcot foot – a review of patient charts Background: Ill-defined areas of water-like signal on bone magnetic resonance imaging (MRI), characterized as bone marrow edema or edema-equivalent signal-changes (EESC), is a hallmark of active-stage pedal neuro-osteoarthropathy (Charcot foot) in painless diabetic neuropathy, and is accompanied by local soft-tissue edema and hyperthermia. The longitudinal effects on EESC of treating the foot

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2018 Diabetic foot & ankle

15. Mast cells and pro-inflammatory cytokines roles in assessment of grape seeds extract anti-inflammatory activity in rat model of carrageenan-induced paw edema (PubMed)

arthritis, but as combination therapy with other proven anti-inflammatory drugs in order to decreasing their toxic impacts has not yet been studied clearly, especially against chemical substances that's induced local inflammation with characteristic edema.Grape seeds extract (GSE) at a concentration of 40 mg/kg B. wt alone or in combination with indomethacin (Indo.) at a dose of 5 mg/Kg B. wt orally given for 10 days prior (gps VI, VII, VIII) or as a single dose after edema induction (gps IX, X, XI (...) Mast cells and pro-inflammatory cytokines roles in assessment of grape seeds extract anti-inflammatory activity in rat model of carrageenan-induced paw edema Reactive oxygen species (ROS)-produced oxidative disorders were involved at the pathophysiology of many inflammatory processes via the generation of pro-inflammatory cytokines and antioxidant defense system suppression. Although herbal antioxidants as mono-therapy relief many inflammatory diseases including, autoimmunity rheumatoid

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2018 Iranian journal of basic medical sciences

16. Targeted Laser in Diabetic Macular Edema

Targeted Laser in Diabetic Macular Edema Targeted Laser in Diabetic Macular Edema - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Targeted Laser in Diabetic Macular Edema (TaLa-DME) The safety (...) -Vingts Information provided by (Responsible Party): Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts Study Details Study Description Go to Brief Summary: Our hypothesis is that implementing laser photocoagulation (IGTL) as an adjunctive treatment to intravitreal injections should lead to a significant reduction in the need for intravitreal injections in patients with diabetic macular edema without adverse consequences for visual acuity. Condition or disease Intervention/treatment Phase

2018 Clinical Trials

17. Diabetic macular edema grading in retinal images using vector quantization and semi-supervised learning (PubMed)

Diabetic macular edema grading in retinal images using vector quantization and semi-supervised learning Diabetic macular edema (DME) is one of the severe complication of diabetic retinopathy causing severe vision loss and leads to blindness in severe cases if left untreated.To grade the severity of DME in retinal images.Firstly, the macular is localized using its anatomical features and the information of the macula location with respect to the optic disc. Secondly, a novel method (...) contributes to macula localization, exudate candidate identification with vector quantization and exudate candidate classification with semi-supervised learning. The proposed method and the state-of-the-art approaches are compared in terms of performance, and experimental results show the proposed system overcomes the challenge of the DME grading and demonstrate a promising effectiveness.

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2018 Technology and Health Care

18. Astroglial Modulation of Hydromineral Balance and Cerebral Edema (PubMed)

Astroglial Modulation of Hydromineral Balance and Cerebral Edema Maintenance of hydromineral balance (HB) is an essential condition for life activity at cellular, tissue, organ and system levels. This activity has been considered as a function of the osmotic regulatory system that focuses on hypothalamic vasopressin (VP) neurons, which can reflexively release VP into the brain and blood to meet the demand of HB. Recently, astrocytes have emerged as an essential component of the osmotic (...) and paraventricular nuclei, can be conveyed, physically and chemically, to adjacent VP neurons, thereby influencing HB at the system level. In addition, astrocytes, particularly those in the circumventricular organs, are involved not only in VP-mediated osmotic regulation, but also in regulation of other osmolality-modulating hormones, including natriuretic peptides and angiotensin. Thus, astrocytes play a role in local/brain and systemic HB. The adaptive astrocytic reactions to osmotic challenges are associated

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2018 Frontiers in molecular neuroscience

19. A Study in Patients With Wet Age-related Macular Degeneration or Diabetic Macular Edema to Assess the freQuency of Use of Intravitreal Aflibercept in Routine Clinical Practices in Latin America

A Study in Patients With Wet Age-related Macular Degeneration or Diabetic Macular Edema to Assess the freQuency of Use of Intravitreal Aflibercept in Routine Clinical Practices in Latin America A Study in Patients With Wet Age-related Macular Degeneration or Diabetic Macular Edema to Assess the freQuency of Use of Intravitreal Aflibercept in Routine Clinical Practices in Latin America - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting (...) registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study in Patients With Wet Age-related Macular Degeneration or Diabetic Macular Edema to Assess the freQuency of Use of Intravitreal Aflibercept in Routine Clinical Practices in Latin America (AQUILA) The safety and scientific validity of this study is the responsibility

2018 Clinical Trials

20. Concordance Between Echocardiographic Assessment Performed in the Initial Phase of Decompensated Cirrhosis With Edema and Ascites by an Expert Intensive Care Physician and a Non-expert Gastroenterologist

Concordance Between Echocardiographic Assessment Performed in the Initial Phase of Decompensated Cirrhosis With Edema and Ascites by an Expert Intensive Care Physician and a Non-expert Gastroenterologist Concordance Between Echocardiographic Assessment Performed in the Initial Phase of Decompensated Cirrhosis With Edema and Ascites by an Expert Intensive Care Physician and a Non-expert Gastroenterologist - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer (...) to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Concordance Between Echocardiographic Assessment Performed in the Initial Phase of Decompensated Cirrhosis With Edema and Ascites by an Expert Intensive Care Physician and a Non-expert Gastroenterologist (EchoCirrho) The safety and scientific validity of this study

2018 Clinical Trials

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