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Lindane

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161. Benign Myalgic Encephalomyelitis (PubMed)

Benign Myalgic Encephalomyelitis 20325349 2010 06 24 2018 11 13 0008-4409 75 7 1956 Oct 01 Canadian Medical Association journal Can Med Assoc J Benign Myalgic Encephalomyelitis. 596-7 Lindan R R eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 2010 3 24 6 0 1956 10 1 0 0 1956 10 1 0 1 ppublish 20325349 PMC1824640 Neurology. 1954 Jul;4(7):506-16 13176669 Lancet. 1954 Nov 20;267(6847):1044-8 13213112 Lancet. 1956 May 26;270(6926):761-4 13320870 Am J Hyg. 1950 Sep;52(2):222-38 14771044

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1956 Canadian Medical Association Journal

162. B.C.G. and Vole Bacillus Vaccines (PubMed)

B.C.G. and Vole Bacillus Vaccines 20325287 2010 06 24 2018 11 13 0008-4409 74 10 1956 May 15 Canadian Medical Association journal Can Med Assoc J B.C.G. and Vole Bacillus Vaccines. 833-4 Lindan R R eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 2010 3 24 6 0 1956 5 15 0 0 1956 5 15 0 1 ppublish 20325287 PMC1824334 Tubercle. 1956 Jan-Feb;37(1):47-57 13299370 Can Med Assoc J. 1943 Jun;48(6):486-8 20322782

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1956 Canadian Medical Association Journal

163. Chemotherapy in Hodgkin's Disease (PubMed)

Chemotherapy in Hodgkin's Disease 20325300 2010 06 24 2018 11 13 0008-4409 74 12 1956 Jun 15 Canadian Medical Association journal Can Med Assoc J Chemotherapy in Hodgkin's Disease. 1002 Lindan R R eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 2010 3 24 6 0 1956 6 15 0 0 1956 6 15 0 1 ppublish 20325300 PMC1824448 Proc Soc Exp Biol Med. 1950 Aug;74(4):708-12 14781156 AMA Arch Intern Med. 1951 Apr;87(4):477-516 14810268 Nature. 1950 Jun 24;165(4208):993-6 15439052

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1956 Canadian Medical Association Journal

164. Rumen Bacterial and Protozoal Responses to Insecticide Substrates (PubMed)

in carbohydrate-limited media, no increases in bacterial counts were indicated. Warburg manometric data showed that paraffin oil-Triton X-155 preparations of dimethoate, Diazinon, lindane, Thiodan and Sevin stimulated gas production in holotrich protozoa. Entodinium simplex, an oligotrich, produced less gas with insecticide substrates per unit of dry weight than did an Isotricha sp. Rumen bacteria and plant debris fractions from ruminal ingesta provided with insecticides did not give increased manometric

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1963 Applied microbiology

165. Effects of Pesticides on Nitrite Oxidation by Nitrobacter agilis (PubMed)

Effects of Pesticides on Nitrite Oxidation by Nitrobacter agilis The influence of pesticides on the growth of Nitrobacter agilis in aerated cultures and on the respiration of N. agilis cell suspensions and cell-free extracts was studied. Two pesticides, aldrin and simazine, were not inhibitory to growth of Nitrobacter, but five compounds [isopropyl N-(3-chlorophenyl) carbamate (CIPC), chlordane, 1,1-dichloro-2,2-bis (p-chlorophenyl) ethane (DDD), heptachlor, and lindane] prevented growth when (...) added to the medium at a concentration of 10 mug/ml. Whereas CIPC and eptam prevented nitrite oxidation by cell suspensions, the addition of DDD and lindane resulted in only partial inhibition of the oxidation. Heptachlor and chlordane also caused only partial inhibition of oxidation, but were more toxic with cell-free extract nitrite oxidase. None of the pesticides inhibited the nitrate reductase activity of cell-free extracts, but most caused some repression of cytochrome c oxidase activity

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1970 Applied microbiology

166. Evaluation of compounds for insecticidal activity on adult mosquitos: 1. Responses of adult mosquitos to some new insecticides (PubMed)

of mosquitos from treated buildings, and their survival rates, are likely to be increased as a result of irritation and consequent activity after only a brief period of contact with phthalthrin (OMS-1011) and other synthetic pyrethroids but not with dieldrin (OMS-18) and lindane (OMS-17) or the carbamates and organophosphorus compounds tested. Mosquitos were not disturbed by exposure to the vapour from deposits of any of the compounds.The rates of action of the different compounds following

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1970 Bulletin of the World Health Organization

167. Ecological considerations in scrub typhus: 3. Methods of area control (PubMed)

acre (2.5 kg/hectare) is also highly effective, but less so than dieldrin. Lindane at the rate of about 5 lb per acre (5.7 kg/hectare) ranks third, but offers protection for only about 2 months. Because of the potential hazards to wildlife when such long-acting compounds are used, application of organophosphorous or carbamate insecticides may be used instead in areas where reapplication every few weeks is feasible. Fenthion and arprocarb are promising compounds for this purpose.

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1968 Bulletin of the World Health Organization

168. Progress in physiological studies of insecticide resistance (PubMed)

Progress in physiological studies of insecticide resistance This study deals first with the progress recently made in investigations on the mode of toxic insecticidal action of DDT, lindane and other chlorinated hydrocarbons, pyrethrins and related chemicals, and organo-phosphates, and secondly with resistance mechanisms to the same insecticides.The author feels that, although good progress is being made towards understanding the physiological mechanisms of resistance, the gaps in present

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1957 Bulletin of the World Health Organization

169. Specific Poisons

of vomiting and aspiration, O 2 , respiratory support, ECG monitoring (ventricular fibrillation can occur early) Diazepam to control seizures For severe anemia, blood transfusions Replacement of K as necessary Epinephrine contraindicated γ -Benzene hexachloride Benzene hexachloride Hexachlorocyclohexane Lindane Irritability, CNS excitation, muscle spasms, atonia, tonic-clonic seizures, respiratory failure, pulmonary edema, nausea, vomiting, obtundation, coma Supportive care, activated charcoal after (...) for severe cyanosis, ascorbic acid, treatment of shock, O 2 For complex cases, possibly dialysis Chlordane See Chlorinated and other halogenated hydrocarbons — Chlorethoxyfos See Organophosphates — Chlorinated and other halogenated hydrocarbons Aldrin Benzene hexachloride Chlordane Chlorothalonil DDD (2-dichlorethane) DDT (chlorophenothane) Dicofol Dieldrin Dienochlor Dilan Endosulfan Endrin Heptachlor Lindane Methoxychlor Perchlordecone Prolan Toxaphene Other chlorinated organic insecticides

2013 Merck Manual (19th Edition)

170. Scabies

be obtained by placing glycerol, mineral oil, or immersion oil over a burrow or papule (to prevent dispersion of mites and material during scraping), which is then unroofed with the edge of a scalpel. The material is then placed on a slide and covered with a coverslip; potassium hydroxide should be avoided because it dissolves fecal pellets. Treatment Topical permethrin or lindane Sometimes oral ivermectin Primary treatment is topical or oral scabicides (see table ). Permethrin is the 1st-line topical (...) drug. Older children and adults should apply permethrin or lindane to the entire body from the neck down and wash it off after 8 to 14 h. Permethrin is often preferred because lindane can be neurotoxic. Treatments should be repeated in 7 days. For infants and young children, permethrin should be applied to the head and neck, avoiding periorbital and perioral regions. Special attention should be given to intertriginous areas, fingernails, toenails, and the umbilicus. Mittens on infants can keep

2013 Merck Manual (19th Edition)

171. Lice

away from the scalp) are seen Contraindicated in patients sensitive to the chrysanthemum family of plants Wet combing with a metal nit comb Should be combined with all of the therapies — Lindane 1% shampoo Apply shampoo, lather for 4–5 min, rinse, and comb with fine-tooth comb Repeat in 1 wk Increasing resistance to drug Toxicity (eg, seizures) not typical with treatment of head lice but not recommended for children 2 yr, people with an uncontrolled seizure disorder, or for pregnant or lactating (...) women Cannot be used on eyelashes Ivermectin 200 mcg/kg po for 1 dose Repeat in 7–10 days Useful for resistant lice Cetaphil ® cleanser Apply, wait 2 min, comb out excess, blow dry hair, wait 8 h, then shampoo and remove nits with wet combing Repeat weekly as necessary — Lice, body — Treatment of pruritus and secondary infection Topical measures not used because body lice are found in clothing Wash clothes and linens and dry them at at least 149° F Dry cleaning or ironing clothes Lice, pubic Lindane

2013 Merck Manual (19th Edition)

172. Epidemic Typhus

have a marked increase in capillary permeability in later stages; thus, IV fluids should be given cautiously to maintain BP while avoiding worsening pulmonary and cerebral edema. Prevention Immunization and louse control are highly effective for prevention. However, vaccines are no longer available. Lice may be eliminated by dusting infested people with malathion or lindane . Key Points Epidemic typhus is prevalent worldwide; humans are the natural reservoir. Infection is transmitted among humans

2013 Merck Manual (19th Edition)

173. Overview of Drug Treatment in Children

Ultrarapid metabolization of codeine to morphine Genetic variant Deaths have occurred after surgery and in a breastfed infant whose mother took codeine Diphenoxylate Respiratory depression Death CNS depression (in immature CNS) Overdose syndrome, usually in children 2 yr Fluoroquinolones Cartilage toxicity Unknown Suspected based on animal studies, but adverse effects in humans unproved—short-term use may be safe Lindane (topical) Seizures CNS toxicity Probably enhanced absorption in children Should

2013 Merck Manual (19th Edition)

175. Treatment of human head lice

for thick hair, while plastic short-tooth combs are best used for treating long and fine hair. Medications [ ] Main article: Today, insecticides used for the treatment of head lice include ( ), ( ), ( ), ( ), , ( , , ), and (spinosyn A and spinosyn D). The only agents approved by the FDA for treatment of pediculosis are topical ivermectin lotion, lindane, malathion, permethrin, piperonyl butoxide with pyrethrins . [ ] has been promoted as a treatment for head lice; however, evidence of its effectiveness

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2012 Wikipedia

176. Prostate cancer risk and exposure to pesticides in British Columbia Farmers. (PubMed)

association between prostate cancer risk and exposure to DDT (OR = 1.68; 95% CI: 1.04-2.70 for high exposure), simazine (OR = 1.89; 95% CI: 1.08-3.33 for high exposure), and lindane (OR = 2.02; 95% CI: 1.15-3.55 for high exposure) is in keeping with those previously reported in the literature. We also observed a significant excess risk for several active ingredients that have not been previously reported in the literature such as dichlone, dinoseb amine, malathion, endosulfan, 2,4-D, 2,4-DB, and carbaryl

2010 Prostate

177. Cys-Loop Receptor Channel Blockers Also Block GLIC (PubMed)

, although the pharmacological profile is distinct from these other proteins. The most potent compound was lindane, a GABA(A) receptor antagonist, with an IC₅₀ of 0.2 μM. Docking studies indicated two potential binding sites for this ligand in the pore, at the 9' or between the 0' and 2' residues. Similar experiments with picrotoxinin (IC₅₀ = 2.6 μM) and rimantadine (IC₅₀ = 2.6 μM) reveal interactions with 2'Thr residues in the GLIC pore. These locations are strongly supported by mutagenesis data (...) for picrotoxinin and lindane, which are less potent in a T2'S version of GLIC. Overall, our data show that the inhibitory profile of the GLIC pore has considerable overlap with those of Cys-loop receptors, but the GLIC pore has a unique pharmacology.Copyright © 2011 Biophysical Society. Published by Elsevier Inc. All rights reserved.

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2011 Biophysical journal

178. Veron Scabies Education and Eradication Program

Details Study Description Go to Brief Summary: The purpose of this project is to develop a community scabies eradication and education program for the highly endemic areas surrounding the Veron community on the eastern tip of the Dominican Republic. It proposes the use of oral Ivermectin as a replacement for topical Lindane--a readily available medical formulation, pesticide, and environmental toxin that is reported to be banned in the Dominican Republic as well as over 80 other countries throughout (...) Drug: Permethrin 5% lotion apply lotion to entire body, excluding head, at bedtime, rinse off following morning, wait one week, repeat application for a total of 2 applications, PRN frequency, NMT 6 applications in 12 months, total duration = 12 months. Other Name: Permethrina locion Outcome Measures Go to Primary Outcome Measures : Scabies incidence [ Time Frame: monthly ] Secondary Outcome Measures : Scabies-induced skin abscess incidence [ Time Frame: monthly ] Incidence of Lindane prescription

2008 Clinical Trials

179. Scabies (PubMed)

for interventions.In this systematic review we present information relating to the effectiveness and safety of the following interventions: benzyl benzoate (topical), crotamiton (topical), lindane (topical), malathion (topical), ivermectin (oral), permethrin (topical), and sulphur compounds (topical).

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2008 BMJ Clinical Evidence

180. Interventions for treating scabies. (PubMed)

was placebo controlled, 16 compared two or more drug treatments, two compared treatment regimens, and one compared different drug vehicles.Fewer treatment failures occurred by day seven with oral ivermectin in one small trial (55 participants). Topical permethrin appeared more effective than oral ivermectin (85 participants, 1 trial), topical crotamiton (194 participants, 2 trials), and topical lindane (753 participants, 5 trials). Permethrin also appeared more effective in reducing itch persistence than (...) either crotamiton (94 participants, 1 trial) or lindane (490 participants, 2 trials). One small trial did not detect a difference between permethrin (a synthetic pyrethroid) and a natural pyrethrin-based topical treatment (40 participants). No significant difference was detected in the number of treatment failures between crotamiton and lindane (100 participants, 1 trial), lindane and sulfur (68 participants, 1 trial), benzyl benzoate and sulfur (158 participants, 1 trial), and benzyl benzoate

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2007 Cochrane

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