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Lindane

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221. Alternatives to lindane Full Text available with Trip Pro

Alternatives to lindane 12952794 2003 10 02 2018 11 30 0820-3946 169 5 2003 Sep 02 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Alternatives to lindane. 389 Nugent Zoann J ZJ eng Letter Comment Canada CMAJ 9711805 0820-3946 0 Insecticides 0 Plant Preparations 59NEE7PCAB Hexachlorocyclohexane AIM IM CMAJ. 2003 May 27;168(11):1447-8 12771080 Hexachlorocyclohexane adverse effects Humans Insecticides adverse effects Lice Infestations drug therapy

2003 CMAJ: Canadian Medical Association Journal

222. Alternatives to lindane Full Text available with Trip Pro

Alternatives to lindane 12952791 2003 10 02 2018 11 30 0820-3946 169 5 2003 Sep 02 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Alternatives to lindane. 389 Bear Soaring S eng Letter Comment Canada CMAJ 9711805 0820-3946 0 Insecticides 59NEE7PCAB Hexachlorocyclohexane 6M3C89ZY6R Nicotine AIM IM CMAJ. 2003 May 27;168(11):1447-8 12771080 Animals Hexachlorocyclohexane adverse effects Humans Insecticides adverse effects Lice Infestations drug

2003 CMAJ: Canadian Medical Association Journal

223. Concerns over lindane treatment for scabies and lice Full Text available with Trip Pro

Concerns over lindane treatment for scabies and lice 12771080 2003 06 20 2018 11 30 0820-3946 168 11 2003 May 27 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Concerns over lindane treatment for scabies and lice. 1447-8 Wooltorton Eric E eng Journal Article Canada CMAJ 9711805 0820-3946 0 Insecticides 59NEE7PCAB Hexachlorocyclohexane AIM IM CMAJ. 2003 Sep 2;169(5):389 12952791 CMAJ. 2003 Sep 2;169(5):389 12952794 Canada Drug Labeling Drug

2003 CMAJ: Canadian Medical Association Journal

224. Partition of the organochlorine insecticide lindane into the human sperm surface induces membrane depolarization and Ca2+ influx. Full Text available with Trip Pro

Partition of the organochlorine insecticide lindane into the human sperm surface induces membrane depolarization and Ca2+ influx. The effects of the insecticide lindane (the gamma-isomer of 1,2,3,4,5,6-hexachlorocyclohexane) on membrane potential, cytosolic free Ca2+ concentration ([Ca2+]i) and surface biophysical properties were studied in human spermatozoa. The insecticide induces rapid, transient and reproducible membrane depolarization and opening of voltage-dependent Ca2+ channels leading (...) to an increase in [Ca2+]i. In contrast with the effect in somatic cells, lindane did not affect gamma-aminobutyric acid receptor-linked Cl- currents. Ca2+ and K+ currents were found to drive lindane-induced membrane depolarization and repolarization respectively, whereas Na+ and Cl- fluxes appear not to have a role in the phenomenon. The insecticide was still able to produce membrane depolarization both in the combined absence of extracellular Ca2+ and Na+ and in high-K+ buffer, suggesting that lindane

1997 Biochemical Journal

225. 1% permethrin cream rinse vs 1% lindane shampoo in treating pediculosis capitis. (Abstract)

1% permethrin cream rinse vs 1% lindane shampoo in treating pediculosis capitis. The therapeutic efficacy and tolerance of a single application of 1% permethrin cream rinse, applied for ten minutes, and a single application of 1% lindane shampoo applied, as recommended by the manufacturer, for four minutes, against the head louse Pediculus humanus var capitis were compared in a single-blinded, randomized, controlled clinical trial. Of 573 patients enrolled at eight centers, 559 were assessable (...) for tolerance and 508 for efficacy. Of the 257 patients treated with 1% permethrin cream rinse, 99% were lice free at 14 days; of the 251 patients treated with 1% lindane shampoo, 85% were lice free at 14 days. The difference is statistically significant. For both treatments, adverse experiences were infrequent, mild, and usually difficult to distinguish from the symptoms of head lice infestation. A single ten-minute application of 1% permethrin cream rinse was well tolerated, highly effective

1986 American journal of diseases of children (1960) Controlled trial quality: uncertain

226. Comparative study of permethrin 1% creme rinse and lindane shampoo for the treatment of head lice. (Abstract)

Comparative study of permethrin 1% creme rinse and lindane shampoo for the treatment of head lice. The efficacy and safety of permethrin 1% creme rinse and lindane shampoo were compared for the treatment of head lice (Pediculus humanus var. capitis). A total of 1040 patients in the Nezahualcoyotl community of Mexico City representing 296 family groups were enrolled and randomized to treatment, with one patient in each family designated as the index patient. Among index patients 98% treated (...) with permethrin and 76% treated with lindane were louse-free 2 weeks after treatment (P less than 0.001). Comparable results were found with nonindex patients as well. Mild dermal reactions, such as pruritus or erythema, occurred in 1.2% of permethrin-treated patients and 2.6% of lindane-treated patients. There were no reports of central nervous system adverse effects or conjunctivitis.

1987 The Pediatric infectious disease journal Controlled trial quality: uncertain

227. Treatment of pediculosis pubis. Clinical comparison of efficacy and tolerance of 1% lindane shampoo vs 1% permethrin creme rinse. (Abstract)

Treatment of pediculosis pubis. Clinical comparison of efficacy and tolerance of 1% lindane shampoo vs 1% permethrin creme rinse. Pediculosis pubis (PP) is a common sexually transmitted disease. Current therapy with 1% lindane or various synergized pyrethrins as a single dose has been accepted as adequate by the medical community. We treated 53 men with the diagnosis of PP with either 1% lindane (Kwell) shampoo for four minutes or 1% permethrin (Nix) creme rinse for ten minutes, according (...) to random assignment. All patients combed with fine-toothed combs immediately after therapy. They were examined for tolerance and efficacy at 24 to 48 hours and again at ten days (eight- to 12-day range). In the lindane group, ten (40%) of 25 subjects were infested at the final assessment. In the permethrin group, 12 (43%) of 28 subjects were infested at the final assessment. The difference was not statistically significant. Both treatments were well tolerated, with one mild adverse reaction in each

1987 Archives of Dermatology Controlled trial quality: uncertain

228. Comparative study of 5% permethrin cream and 1% lindane lotion for the treatment of scabies. (Abstract)

Comparative study of 5% permethrin cream and 1% lindane lotion for the treatment of scabies. A multicenter, randomized, investigator-blind controlled trial was conducted to compare the safety and efficacy of a single, whole-body application of 5% permethrin cream with that of 1% lindane lotion for the treatment of scabies in 467 patients. At 14 +/- 3 days after treatment, the mean active lesion count decreased from pretreatment levels of 85 (range, 4 to 600) in both treatment groups to 14 (...) (range, 0 to 133) in the permethrin group and to 15 lesions (range, 0 to 500) in the lindane group. At 28 +/- 7 days after treatment, complete resolution had occurred in 181 (91%) of 199 patients treated with permethrin and in 176 (86%) of 205 patients given lindane. Pruritus due to scabies persisted at 28 +/- 7 days in 14% of the permethrin group and in 25% of the lindane group. The most frequent adverse effects were new or increased pruritus and mild, transient burning or stinging; the latter

1990 Archives of Dermatology Controlled trial quality: uncertain

229. Equivalent therapeutic efficacy and safety of ivermectin and lindane in the treatment of human scabies. (Abstract)

Equivalent therapeutic efficacy and safety of ivermectin and lindane in the treatment of human scabies. To compare the therapeutic efficacy and safety of ivermectin and lindane for the treatment of human scabies.Randomized, prospective, controlled, double-blind, "double-dummy," and parallel clinical study.A single department of dermatology at a hospital in Buenos Aires, Argentina.Patients were outpatients, hospitalized patients, and those referred to our hospital from nursing homes and asylums (...) . Fifty-three patients had clinical signs and symptoms compatible with scabies.Patients received either a single oral dose of ivermectin (150-200 microg/kg of body weight) or a topical application of 1% lindane solution. Treatment was repeated after 15 days if clinical cure had not occurred.Clinical healing and adverse effects.Of 53 patients, 43 (81%) completed the study, 19 in the group treated with ivermectin and 24 in the group treated with lindane. At day 15, 14 patients (74%; 95% confidence

1999 Archives of Dermatology Controlled trial quality: predicted high

230. Oral ivermectin in scabies patients: a comparison with 1% topical lindane lotion. (Abstract)

Oral ivermectin in scabies patients: a comparison with 1% topical lindane lotion. Scabies. which constitutes a significant proportion of the outpatient attendance in tropical dermatology clinics, has so far been treated with lindane, crotamiton, sulphur, permethrin, etc. Ivermectin, an orally administered drug, was tried in scabies patients and compared with 1% topical lindane lotion to evaluate its effects and toxicity profile. Two hundred scabies patients were randomly allocated to one of two (...) groups. One group received oral invermectin in a single dose of 200 micrograms/kg body weight. The other received 1% lindane lotion for topical application overnight. Patients were assessed after 48 hours, two weeks and four weeks. After a period of four weeks, 82.6% of the patients in the ivermectin group showed marked improvement; only 44.44% of the patients in the lindance group showed a similar response. A side effects in the form of severe headache were noted in one patient in group A. Oral

2001 The Journal of dermatology Controlled trial quality: uncertain

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