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4,143 results for

Life-Threatening Drug-Induced Rashes

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4141. Treating Patients With a History of Non-Life Threatening Allergic Reaction to Penicillin With Penicillin

: August 15, 2006 Sponsor: Meir Medical Center Information provided by: Meir Medical Center Study Details Study Description Go to Brief Summary: The purpose of this study is to examine whether oral challenge with penicillin for patients with a known history of non-life threatening allergic reaction to penicillin is well-tolerated irrespective of skin-testing results Condition or disease Intervention/treatment Phase Penicillin Allergy Drug: Penicillin test and challenge Phase 4 Detailed Description (...) Treating Patients With a History of Non-Life Threatening Allergic Reaction to Penicillin With Penicillin Treating Patients With a History of Non-Life Threatening Allergic Reaction to Penicillin With Penicillin - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2006 Clinical Trials

4142. Tetracycline in Preventing Skin Rash in Patients Who Are Receiving Drugs Such as Gefitinib and Cetuximab for Cancer

it works compared to placebo in preventing skin rash in patients who are receiving drugs such as gefitinib or cetuximab for cancer. Condition or disease Intervention/treatment Phase Unspecified Adult Solid Tumor, Protocol Specific Drug: tetracycline hydrochloride Other: placebo Not Applicable Detailed Description: OBJECTIVES: Compare the 1-month incidence and severity of gefitinib-, cetuximab-, or other epidermal growth factor receptor inhibitor-induced skin rash development in patients with cancer (...) treated with tetracycline vs placebo. Compare the toxicity of these drugs in these patients. Compare the quality of life of patients treated with these drugs who develop vs those who do not develop a rash. Determine whether patients who discontinue tetracycline at 1 month develop a rash. OUTLINE: This is a randomized, double-blind, placebo-controlled, multicenter study. Patients are stratified according to prior chemotherapy regimen (first-line therapy vs other), concurrent epidermal growth factor

2004 Clinical Trials

4143. Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

of unacceptable toxicity Systemic lupus erythematosus: Malar rash Discoid rash Photosensitivity Oral ulcers Arthritis Serositis Renal disorder Neurologic disorder Hematologic disorder Immunologic disorder Antinuclear antibody Must have at least 4 of 7 variables on the lupus activity scale measured Evidence of potential life threatening involvement of at least 1 internal organ system Endocardial and/or myocardial disease Central nervous system disease Pulmonary parenchymal disease Renal disease defined as WHO (...) Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2000 Clinical Trials

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