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Lidocaine Patch

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141. Lidocaine/tetracaine medicated plaster: in minor dermatological and needle puncture procedures. (PubMed)

Lidocaine/tetracaine medicated plaster: in minor dermatological and needle puncture procedures. The lidocaine/tetracaine medicated plaster comprises a lidocaine/tetracaine 70 mg/70 mg patch and a controlled heat-assisted drug delivery pod that increases the diffusion of lidocaine and tetracaine into the dermis. Following a 1-hour application period, systemic absorption of lidocaine or tetracaine from the plaster was minimal. The lidocaine/tetracaine medicated plaster provided effective pain (...) relief for adult (including elderly) patients undergoing minor dermatological procedures and for adult and paediatric patients undergoing vascular access procedures. In randomized, double-blind clinical trials, patient-reported median pain scores were significantly lower with the lidocaine/tetracaine medicated plaster than with an identical plaster containing placebo in patients undergoing minor dermatological or vascular access procedures. Furthermore, patient-reported median pain scores were

2010 Drugs

142. Topical Lidocaine: Predictors of Response in Peripheral Nerve Injury

by (Responsible Party): Danish Pain Research Center Study Details Study Description Go to Brief Summary: The primary purpose is to study the predictive value of preserved nociceptors and large afferent fibers and dynamic mechanical allodynia on the effect of lidocaine patch. The primary outcome measure is the predictive role for these three measures for obtaining a response to lidocaine. A responder is defined as a person with at least a 2-point pain reduction to lidocaine (change in median pain intensity (...) /treatment Phase Neuropathic Pain Drug: Topical lidocaine patch Phase 4 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 24 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Evaluation of Predictors of Response for the Efficacy of Topical Lidocaine Patch (Versatis) on Chronic Neuropathic Pain After Peripheral Nerve Injury Study Start Date : April 2010 Actual

2010 Clinical Trials

143. Use of Topical Lidocaine to Reduce Pain in Patients With Diabetic Neuropathy

, 2011 Sponsor: Albany Medical College Collaborator: Endo Pharmaceuticals Information provided by: Albany Medical College Study Details Study Description Go to Brief Summary: The purpose of this study is to see if an investigational drug known as the lidocaine 5% patch is safe and effective in reducing the symptoms of diabetic neuropathy, to examine how topical lidocaine affects the nerve endings, and to determine whether treatment with the lidocaine patch can prevent the potential progression (...) Lidocaine (Lidoderm 5% Patch) to Reduce Pain in Patients With Diabetic Neuropathy: Does the Density and Subtype of Sodium Channels Affect Response? Study Start Date : October 2009 Estimated Primary Completion Date : October 2012 Estimated Study Completion Date : October 2013 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Healthy control patients Subjects 18 to 70 years of age, non-diabetic with no nervous

2010 Clinical Trials

144. A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0.3% Lidocain Hydrochloride, Prevelle Silk, for Superficial, Vertical Perioral Lines and Superficial, Horizontal, Lateral Canthal Lines

A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0.3% Lidocain Hydrochloride, Prevelle Silk, for Superficial, Vertical Perioral Lines and Superficial, Horizontal, Lateral Canthal Lines A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0.3% Lidocain Hydrochloride, Prevelle Silk, for Superficial, Vertical Perioral Lines and Superficial, Horizontal, Lateral Canthal Lines - Full Text (...) View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0.3% Lidocain Hydrochloride, Prevelle Silk, for Superficial

2010 Clinical Trials

145. Acute auditory and vestibular symptoms associated with heat and transdermal lidocaine. (PubMed)

Acute auditory and vestibular symptoms associated with heat and transdermal lidocaine. To describe a case of systemic lidocaine toxicity from the simultaneous use of transdermal patches and a heating pad.Case report and discussion.The focus of this case report are the interesting neuro-otologic signs of central lidocaine toxicity that occurred after a patient fell asleep on a heating pad with his Lidoderm patches in place. Hearing improvement, tinnitus reduction, and severe dizziness and ataxia

2010 Clinical Journal of Pain

146. A randomized, controlled study comparing a lidocaine patch, a placebo patch, and anesthetic injection for treatment of trigger points in patients with myofascial pain syndrome: evaluation of pain and somatic pain thresholds. (PubMed)

A randomized, controlled study comparing a lidocaine patch, a placebo patch, and anesthetic injection for treatment of trigger points in patients with myofascial pain syndrome: evaluation of pain and somatic pain thresholds. Myofascial pain syndrome (MPS), a regional pain condition caused by trigger points in muscle or muscle fascia, produces muscle pain, tenderness, and disability. The gold standard of treatment for MPS-infiltration of trigger points with anesthetic-may provoke discomfort (...) to the patients and require medical intervention.This study was designed to compare the effects of a topical lidocaine patch, a placebo patch, and injection of anesthetic (infiltration) for the symptoms of MPS in terms of pain, disability, and local tissue hypersensitivity, and to determine the acceptability of the lidocaine patch to the patients.Patients were randomly allocated to receive 1 of 3 treatments: a lidocaine patch applied to the trigger point for 4 days (replacement every 12 hours; total daily

2009 Clinical therapeutics Controlled trial quality: predicted high

147. Heated lidocaine/tetracaine patch (Synera, Rapydan) compared with lidocaine/prilocaine cream (EMLA) for topical anaesthesia before vascular access. (PubMed)

Heated lidocaine/tetracaine patch (Synera, Rapydan) compared with lidocaine/prilocaine cream (EMLA) for topical anaesthesia before vascular access. We compared the lidocaine/tetracaine patch [Synera (USA), Rapydan (Europe)], a novel heat-aided patch using a eutectic mixture of lidocaine 70 mg and tetracaine 70 mg, with a eutectic mixture of lidocaine 25 mg ml(-1) and prilocaine 25 mg ml(-1) (EMLA Cream). The agents were administered at different time periods for local topical anaesthesia before (...) a vascular access procedure.In this double-blind, paired study, 82 adult volunteers were randomized to receive the lidocaine/tetracaine patch on one anticubital surface and lidocaine/prilocaine cream on the other concurrently for 10, 20, 30, or 60 min before a vascular access procedure. Subjects rated pain intensity using a 100 mm visual analogue scale (VAS). Skin reactions and adverse events were also evaluated.Median VAS scores were significantly lower for the lidocaine/tetracaine patch than

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2009 British Journal of Anaesthesia Controlled trial quality: uncertain

149. Neuropathic pain

was 6.8. Tramadol The IASP Guidelines, based on the (see also ), made a weak GRADE recommendation for second-line use based on positive trials and moderate quality of evidence, but potential safety concerns and an increase in deaths associated with its use have been reported. NNT/NNH were 4.7/12.6. The on tramadol for neuropathic pain in adults used a more stringent standard of ≥ 50% pain relief and fewer studies compared to the 2015 Finnerup study, but found a similar NNT of 4.4. Lidocaine (...) (lignocaine) patches The IASP Guidelines, based on the (see also ), made a weak GRADE recommendation for second-line use for peripheral neuropathic pain use based on poor quality of evidence, but high values and preferences, and excellent balance between desirable and undesirable side effects. NNT/NNH were not available. While the lack of high quality studies resulted in no pooling of data and meta-analysis was not performed, individual studies indicated some improvement compared to placebo

2019 National Prescribing Service Limited (Australia)

150. Diagnosis and management of gonorrhoea and syphilis

days (range 9-90) Secondary • Widespread mucocutaneous rash and generalized lymphadenopathy • Mucous patches (buccal, lingual and genital) and highly infectious condylomata lata a?ecting warm, moist areas (mostly the perineum and anus) • Hepatitis; glomerulonephritis; splenomegaly; neurological complications (meningitis, hearing loss, tinnitus); uveitis, optic neuropathy, keratitis Three months after infection 4–10 weeks after the appearance of the initial chancre Latent • Asymptomatic in 75

2019 Belgian Health Care Knowledge Centre

151. Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers

Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You (...) have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00889642

2009 Clinical Trials

152. Lidocaine Patch Versus Celecoxib in Pain From Osteoarthritis of the Knee

Lidocaine Patch Versus Celecoxib in Pain From Osteoarthritis of the Knee Lidocaine Patch Versus Celecoxib in Pain From Osteoarthritis of the Knee - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Lidocaine (...) Type : Interventional (Clinical Trial) Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: A Randomized, Open-Label Study Comparing the Efficacy and Safety of Lidocaine Patch 5% With Celecoxib 200 mg in Patients With Pain From Osteoarthritis of the Knee Study Start Date : June 2004 Actual Primary Completion Date : November 2004 Actual Study Completion Date : November 2004 Resource links provided by the National Library

2009 Clinical Trials

153. Topical Lidocaine Patch in Low Back Pain

Topical Lidocaine Patch in Low Back Pain Topical Lidocaine Patch in Low Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Topical Lidocaine Patch in Low Back Pain The safety and scientific validity (...) ) Primary Purpose: Treatment Official Title: Open-Label Study Assessing the Efficacy of Topical Lidocaine Patch in Treatment of Low Back Pain Study Start Date : March 2002 Actual Primary Completion Date : October 2002 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Lidoderm® Commercially available Lidoderm (lidocaine patch 5%), up to four patches applied topically once daily (q24h

2009 Clinical Trials

154. Pilot Study of Lidocaine 5% Patch Versus Placebo in Patients With Osteoarthritis Pain of the Knee

Pilot Study of Lidocaine 5% Patch Versus Placebo in Patients With Osteoarthritis Pain of the Knee Pilot Study of Lidocaine 5% Patch Versus Placebo in Patients With Osteoarthritis Pain of the Knee - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Pilot Study of Lidocaine 5% Patch Versus Placebo in Patients With Osteoarthritis Pain of the Knee The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00904462 Recruitment Status : Completed First Posted : May 19, 2009 Last Update Posted : February 10, 2010

2009 Clinical Trials

155. Lidocaine Patch 5% Versus Celecoxib 200 mg in Chronic Axial Low Back Pain

Lidocaine Patch 5% Versus Celecoxib 200 mg in Chronic Axial Low Back Pain Lidocaine Patch 5% Versus Celecoxib 200 mg in Chronic Axial Low Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Lidocaine (...) Pharmaceuticals Information provided by: Endo Pharmaceuticals Study Details Study Description Go to Brief Summary: Patients who had axial lower back pain (LBP) with or without radiation present for at least 3 months and had daily moderate to severe LBP as the primary source of pain participated in a Phase IV clinical trial to assess the efficacy of lidocaine patch 5% compared to celecoxib 200 mg in treating chronic axial LBP with and without radiation. Condition or disease Intervention/treatment Phase Chronic

2009 Clinical Trials

156. A Study Comparing The Efficacy And Safety Of Lidocaine 5% Patch With Placebo In Patients With Chronic Axial Low Back Pain

A Study Comparing The Efficacy And Safety Of Lidocaine 5% Patch With Placebo In Patients With Chronic Axial Low Back Pain A Study Comparing The Efficacy And Safety Of Lidocaine 5% Patch With Placebo In Patients With Chronic Axial Low Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. A Study Comparing The Efficacy And Safety Of Lidocaine 5% Patch With Placebo In Patients With Chronic Axial Low Back Pain The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00904111 Recruitment Status : Completed First

2009 Clinical Trials

157. Lidoderm® (Lidocaine Patch 5%) in Diabetic and Idiopathic Neuropathy

Lidoderm® (Lidocaine Patch 5%) in Diabetic and Idiopathic Neuropathy Lidoderm® (Lidocaine Patch 5%) in Diabetic and Idiopathic Neuropathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Lidoderm® (...) (Lidocaine Patch 5%) in Diabetic and Idiopathic Neuropathy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00903851 Recruitment Status : Completed First Posted : May 19, 2009 Last Update Posted : February 15, 2010 Sponsor: Endo Pharmaceuticals Information provided by: Endo Pharmaceuticals Study Details

2009 Clinical Trials

158. Use of a lidocaine patch in the management of postsurgical neuropathic pain in patients with cancer: a phase III double-blind crossover study (N01CB). (PubMed)

Use of a lidocaine patch in the management of postsurgical neuropathic pain in patients with cancer: a phase III double-blind crossover study (N01CB). Current therapies often have limited efficacy and untenable side effects when used to treat persistent incisional pain following cancer-related surgery. Lidocaine patches reduce neuropathic pain from herpes zoster but their benefits for persistent cancer-related postsurgical incisional pain remain unclear.Multicenter, double-blind, randomized (...) , two-period crossover trial.Twenty-eight cancer patients with postsurgical incisional pain were randomly assigned to receive either lidocaine patches followed by placebo patches or the reverse. Each study period lasted 4 weeks. Patches were applied daily upon waking and left in place for a maximum of 18 h. The primary outcome measure, an 11-point pain intensity rating scale, was administered weekly. Secondary outcomes were administered weekly (Brief Pain Inventory-Short Form(BPI-SF), Subject Global

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2009 Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer Controlled trial quality: predicted high

159. Lidocaine patch for postoperative analgesia after radical retropubic prostatectomy. (PubMed)

Lidocaine patch for postoperative analgesia after radical retropubic prostatectomy. In a prospective, double-blind, placebo-controlled study, patients undergoing radical retropubic prostatectomy under general anesthesia were randomly assigned to receive a lidocaine patch or placebo applied on each side of the wound at the end of surgery. Data were collected for 24 h after surgery. Seventy patients completed the study (36 lidocaine group, 34 placebo group). Demographics and postoperative (...) morphine consumption were not different between the groups. However, the lidocaine patch group reported significantly less pain on coughing (19%-33% reduction) over all time periods (treatment vs placebo P < 0.0001, time x treatment P = 0.3056) and at rest (17%-32% reduction) for up to 6 h (treatment vs placebo P = 0.0003, time x treatment P = 0.0130).

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2009 Anesthesia and analgesia Controlled trial quality: uncertain

160. Early experience with lidocaine patch for postoperative pain control after laparoscopic ventral hernia repair. (PubMed)

Early experience with lidocaine patch for postoperative pain control after laparoscopic ventral hernia repair. Reduced postoperative pain is one of the many factors that have driven the growing emphasis on the role of laparoscopic surgery for surgical management. Several studies have documented the advantages of the laparoscopic repair of ventral hernias compared to the open ventral herniorraphy. However, the laparoscopic approach may be associated with more postoperative pain initially (...) . In this preliminary study, we present data from our early experience with the use of a lidocaine patch for pain control in the immediate postoperative period following laparoscopic ventral hernia repair (LVH).Thirty consecutive patients underwent laparoscopic ventral herniorraphy (LVH) and were selected randomly and placed into one of two groups. In one group, we placed a lidocaine patch (LP) (Lidoderm, Endo Pharmaceuticals, Inc., Chadds Ford, PA) on the anterior abdominal wall corresponding to the placement site

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2009 International journal of surgery (London, England) Controlled trial quality: uncertain

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