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Lidocaine Patch

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21. Effects of transdermal lidocaine or lidocaine with prilocaine or tetracaine on mechanical superficial sensation and nociceptive thermal thresholds in horses. (Abstract)

superficial sensation via von Frey filaments and nociceptive thermal thresholds were performed. A 5% lidocaine patch (12 hour exposure, treatment L), a lidocaine/prilocaine cream (each 2.5%, treatment LP) and a lidocaine/tetracaine cream (each 7%, treatment LT) were applied (both 2 hour exposure). The same product was applied at the same location bilaterally, but on the right side an epidermal micro-perforation (dermaroller, 1200 needles) was performed prior to application. A total of five more (...) ; 87.7±14.4) after the removal of the respective product compared to baseline (66.1±9.3; 69.9±8.3; 76.5±7.8). Superficial mechanical sensation was decreased by the lidocaine-and-tetracaine cream at all time points, and by the lidocaine patch and lidocaine-and-prilocaine cream for three measurements.Eutectic mixtures of lidocaine with either prilocaine or tetracaine led to a reduction in thermal nociception and mechanical sensation for up to 2 hours.Copyright © 2017 Association of Veterinary

2018 Veterinary anaesthesia and analgesia Controlled trial quality: uncertain

22. Pilot Study Comparing Topical Anesthetic Agents in Pterygium Surgery: Subconjunctival Injection Versus 2% Lidocaine Gel Versus 5% Lidocaine Gel. (Abstract)

% lidocaine gel. Both lidocaine gel groups could receive another gel dose as needed during the procedure. The primary outcome was pain, which was experienced during and after surgery. The assessment was done using a 10-point linear analog scale at predetermined stages of surgery (1-first incision, 2-pterygium body excision, 3-conjunctival suturing, 4-immediate postoperative period after patching, and 5-assessment by a trained nurse in the absence of a surgeon after operation).We enrolled 45 consecutive (...) Pilot Study Comparing Topical Anesthetic Agents in Pterygium Surgery: Subconjunctival Injection Versus 2% Lidocaine Gel Versus 5% Lidocaine Gel. To compare the efficacy of different concentrations of topical lidocaine gel with standard subconjunctival anesthesia.This was a prospective randomized controlled pilot study with 3 different groups. Group SC received subconjunctival lidocaine and proparacaine drops as needed during surgery. Group L2 received 2% lidocaine gel and group L5 received 5

2018 Cornea Controlled trial quality: uncertain

23. A comparison of transdermal over-the-counter lidocaine 3.6% menthol 1.25%, Rx lidocaine 5% and placebo for back pain and arthritis. (Abstract)

A comparison of transdermal over-the-counter lidocaine 3.6% menthol 1.25%, Rx lidocaine 5% and placebo for back pain and arthritis. Transdermal lidocaine therapy has become a gold standard as part of a treatment regimen for patients who suffer from localized pain. We compared transdermal patches: over-the-counter (OTC) lidocaine 3.6% combined with menthol 1.25%, prescription lidocaine 5% (Rx) and placebo.In a double-blind, placebo-controlled trial, 87 patients were randomized to: OTC, Rx

2018 Pain management Controlled trial quality: predicted high

24. Lidocaine Patch

Lidocaine Patch Lidocaine Patch Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Lidocaine Patch Lidocaine Patch Aka: Lidocaine Patch (...) ) These images are a random sampling from a Bing search on the term "Lidocaine Patch." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Cost: Medications lidoderm (on 4/19/2017 at ) LIDODERM 5% PATCH Generic $3.04 each FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans

2017 FP Notebook

25. Pretreatmet with 5% lidocaine patch reduces cannula-induced and propofol-induced pain: a randomized, double-blind, placebo-controlled study. Full Text available with Trip Pro

Pretreatmet with 5% lidocaine patch reduces cannula-induced and propofol-induced pain: a randomized, double-blind, placebo-controlled study. The purpose of this study was to determine the efficacy of 5% lidocaine patch in reducing propofol-induced pain and cannula-induced pain.In a randomized, double-blind study, 126 patients were divided into one of three groups: pretreatment with a 5% lidocaine patch (Lidotop®) and premixed 2 ml of normal saline with 1.5 mg/kg of 1% propofol (Group (...) A); pretreatment with a placebo patch and premixed 2 ml of normal saline with 1.5 mg/kg of 1% propofol (Group B); or pretreatment with a placebo patch and premixed 2 ml of 2% lidocaine (40 mg) with 1.5 mg/kg of 1% propofol (Group C) for induction of anesthesia. Pain severity was evaluated on a four-point verbal rating scale during intravenous cannulation, propofol injection, and 24 h after the operation (recall).Eighteen patients (47.4%) in Group A complained of cannula-induced pain compared with 35 (94.6

2016 Korean journal of anesthesiology Controlled trial quality: uncertain

26. Lidoderm Patch (Lidocaine 5%) for Tinnitus Treatment

Lidoderm Patch (Lidocaine 5%) for Tinnitus Treatment Lidoderm Patch (Lidocaine 5%) for Tinnitus Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Lidoderm Patch (Lidocaine 5%) for Tinnitus Treatment (...) by (Responsible Party): HaEmek Medical Center, Israel Study Details Study Description Go to Brief Summary: The investigators like to learn whether Lidoderm patch (lidocaine 5%) helps tinnitus patients. so far it is known that lidocaine I.V do helps tinnitus but until now it is not clear if other means of drug delivery (e.g lidocaine patch) help tinnitus. The investigators are going to compare 1 day of treatment with lidoderm patch cream Versus (VS.) tegaderm patch (containing no drug) in treating tinnitus

2016 Clinical Trials

27. Preventive Skin Analgesia With Lidocaine Patch 5% for Controlling Post-thoracotomy Pain

Preventive Skin Analgesia With Lidocaine Patch 5% for Controlling Post-thoracotomy Pain Preventive Skin Analgesia With Lidocaine Patch 5% for Controlling Post-thoracotomy Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Preventive Skin Analgesia With Lidocaine Patch 5% for Controlling Post-thoracotomy Pain The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02751619 Recruitment Status : Completed First Posted : April 26, 2016 Last Update Posted : April 26, 2016 Sponsor: University of Campania "Luigi

2016 Clinical Trials

28. Lidocaine Patch (5%) in Treatment of Persistent Inguinal Postherniorrhaphy Pain: A Randomized, Double-blind, Placebo-controlled, Crossover Trial Full Text available with Trip Pro

Lidocaine Patch (5%) in Treatment of Persistent Inguinal Postherniorrhaphy Pain: A Randomized, Double-blind, Placebo-controlled, Crossover Trial Evidence-based pharmacological treatment options for patients with persistent inguinal postherniorrhaphy pain are lacking.Twenty-one male patients, with severe, unilateral, persistent inguinal postherniorrhaphy pain, participated in a randomized, double-blind, placebo-controlled crossover trial, receiving lidocaine patch (5%) and placebo patch (...) and after each treatment period. The primary outcome was change in pain intensity assessed as the difference in summed pain intensity differences between lidocaine and placebo patch treatments.There was no difference in summed pain intensity differences between lidocaine and placebo patch treatments in all patients (mean difference 6.2% [95% CI = -6.6 to 18.9%]; P = 0.33) or in the two subgroups (+/- thermal "hyposensitivity"). The quantitative sensory testing (n = 21) demonstrated an increased pressure

2013 EvidenceUpdates Controlled trial quality: predicted high

29. Etodolac-lidocaine Patch in Subjects Experiencing Acute Delayed Onset Muscle Soreness

Etodolac-lidocaine Patch in Subjects Experiencing Acute Delayed Onset Muscle Soreness Etodolac-lidocaine Patch in Subjects Experiencing Acute Delayed Onset Muscle Soreness - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Etodolac-lidocaine Patch in Subjects Experiencing Acute Delayed Onset Muscle Soreness The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02695381 Recruitment Status : Completed First Posted : March 1, 2016 Last Update Posted : September 12, 2016 Sponsor: MEDRx USA, Inc. Information provided

2016 Clinical Trials

30. A Trial of Lidocaine Patch for Lower Limb Amputation Pain

A Trial of Lidocaine Patch for Lower Limb Amputation Pain A Trial of Lidocaine Patch for Lower Limb Amputation Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Trial of Lidocaine Patch for Lower Limb (...) for treatment. Scar hyperalgesia involves peripheral mechanisms and results frim the production of substances liberated by damaged skin cells. These inflammatory substances lower the pain threshold by altering the chemical environment of skin nerve endings. Scan hyperalgesia is associated with secondary mechanical hyperalgesia in the skin area around the scar. The lidocaine patch 5% is a topical analgesic acting by blocking sodium channels of peripheral nerve endings and by inhibiting ectopic discharges

2016 Clinical Trials

31. Effect of Lidocaine Patch for Shoulder Pain in Laparoscopic Cholecystectomy

Effect of Lidocaine Patch for Shoulder Pain in Laparoscopic Cholecystectomy Effect of Lidocaine Patch for Shoulder Pain in Laparoscopic Cholecystectomy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect (...) of Lidocaine Patch for Shoulder Pain in Laparoscopic Cholecystectomy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02827136 Recruitment Status : Completed First Posted : July 11, 2016 Last Update Posted : December 19, 2017 Sponsor: Ajou University School of Medicine Information provided by (Responsible

2016 Clinical Trials

32. Intravenous administration of lidocaine directly acts on spinal dorsal horn and produces analgesic effect: An in vivo patch-clamp analysis Full Text available with Trip Pro

Intravenous administration of lidocaine directly acts on spinal dorsal horn and produces analgesic effect: An in vivo patch-clamp analysis Intravenous lidocaine administration produces an analgesic effect in various pain states, such as neuropathic and acute pain, although the underlying mechanisms remains unclear. Here, we hypothesized that intravenous lidocaine acts on spinal cord neurons and induces analgesia in acute pain. We therefore examined the action of intravenous lidocaine (...) in the spinal cord using the in vivo patch-clamp technique. We first investigated the effects of intravenous lidocaine using behavioural measures in rats. We then performed in vivo patch-clamp recording from spinal substantia gelatinosa (SG) neurons. Intravenous lidocaine had a dose-dependent analgesic effect on the withdrawal response to noxious mechanical stimuli. In the electrophysiological experiments, intravenous lidocaine inhibited the excitatory postsynaptic currents (EPSCs) evoked by noxious pinch

2016 Scientific reports

33. Lidocaine Skin Patch (Lidopat® 5%) Is Effective in the Treatment of Traumatic Rib Fractures: A Prospective Double-Blinded and Vehicle-Controlled Study. Full Text available with Trip Pro

Lidocaine Skin Patch (Lidopat® 5%) Is Effective in the Treatment of Traumatic Rib Fractures: A Prospective Double-Blinded and Vehicle-Controlled Study. The purpose of this study was to determine the efficacy of the Lidopat(®) 5% skin patch in relieving rib fracture pain.From June 2009 to May 2011, 44 trauma patients with isolated rib fractures were enrolled in this study and randomized in a double-blind method into 2 groups. The experimental group (group E: 27 patients) used a Lidopat(®) 5 (...) % skin patch at the trauma site and took an oral analgesic drug for pain relief. The placebo group (group P: 17 patients) used a placebo vehicle patch and an oral analgesic drug.The mean age, weight and hospital stay of patients were 56.8 ± 13.8 years, 67.4 ± 12.6 kg and 6.34 ± 1.3 days, respectively. In the first 4 days, there were no significant differences in pain scores between the groups (p > 0.05). After the 5th day, the average pain score was significantly less in group E (mean 1.5) than

2015 Medical principles and practice : international journal of the Kuwait University, Health Science Centre Controlled trial quality: uncertain

34. Lidocaine patch for acute pain management: a meta-analysis of prospective controlled trials. Full Text available with Trip Pro

Lidocaine patch for acute pain management: a meta-analysis of prospective controlled trials. Local anesthetic is one of the cornerstones of multimodal analgesia. We investigated the efficacy of the lidocaine patch for acute pain management.We searched MEDLINE, CINAHL, Scopus, and the Cochrane Controlled Trials Register for published prospective controlled clinical trials that evaluated the analgesic effect of the lidocaine patch for acute or postoperative pain management (1966--2014 (...) ). The outcomes were postoperative opioid consumption, pain intensity and length of hospital stay.Five trials comparing the lidocaine patch with control (no treatment/placebo) for acute or postoperative pain treatment/management were included in this meta-analysis. Data was analyzed on 251 patients. Between the lidocaine patch group and the control group, no significant difference was found for all three outcomes (all p > 0.05). For postoperative opioid consumption, mean difference (MD) was -8.2 mg morphine

2015 Current medical research and opinion

35. Pain relief with lidocaine 5% patch in localized peripheral neuropathic pain in relation to pain phenotype. (Abstract)

Pain relief with lidocaine 5% patch in localized peripheral neuropathic pain in relation to pain phenotype. In neuropathic pain with irritable nociceptor (IN) phenotype, upregulation of sodium channels on nociceptors is supposed to be an important pain mechanism that may be targeted by topical sodium channel blockade. This randomised, double-blind, phenotype panel, crossover study with 4-week treatment periods of lidocaine 5% patch and placebo was performed to search for phenotype differences (...) (0.8, 95% CI: 0.4-1.2, P < 0.001) and deep aching pain (0.6, 95% CI: 0.1-1.0, P = 0.013). In conclusion, lidocaine 5% patch had an effect on peripheral neuropathic pain, and it may be most efficacious in patients with IN phenotype. The lack of significant phenotype differences may be caused by too low statistical power.

2015 Pain Controlled trial quality: predicted high

36. Effect of lidocaine patches on upper trapezius EMG activity and pain intensity in patients with myofascial trigger points: A randomized clinical study. Full Text available with Trip Pro

Effect of lidocaine patches on upper trapezius EMG activity and pain intensity in patients with myofascial trigger points: A randomized clinical study. To compare the effects of 5% lidocaine patches and placebo patches on pain intensity and electromyographic (EMG) activity of an active myofascial trigger point (MTrP) of the upper trapezius muscle.Thirty-six patients with a MTrP in the upper trapezius muscle were randomly divided into two groups: 20 patients received lidocaine patches (lidocaine (...) group) and 16 patients received placebo patches (placebo group). They used the patches for 12 h each day, for 2 weeks. The patch was applied to the skin over the upper trapezius MTrP. Spontaneous pain, pressure pain thresholds, pain provoked by a 4-kg pressure applied to the MTrP and trapezius EMG activity were measured before and after treatment.Baseline spontaneous pain values were similar in both groups and significantly lower in the lidocaine group than the placebo group after treatment

2015 Acta odontologica Scandinavica Controlled trial quality: uncertain

37. Lidocaine 5% Patch for Treatment of Acute Pain After Robotic Cardiac Surgery and Prevention of Persistent Incisional Pain: A Randomized, Placebo-Controlled, Double-Blind Trial. Full Text available with Trip Pro

Lidocaine 5% Patch for Treatment of Acute Pain After Robotic Cardiac Surgery and Prevention of Persistent Incisional Pain: A Randomized, Placebo-Controlled, Double-Blind Trial. To test the hypotheses that lidocaine 5% patches decrease the severity of acute pain and incidence of persistent incisional pain after robotic cardiac valve surgery.A randomized, placebo-controlled, double-blind trial.Tertiary care academic medical center.Patients having robotic cardiac valve surgery.Patients having (...) robotic cardiac valve surgery were randomly assigned to 5% lidocaine patches or identical-appearing placebo patches. Patches were applied around each incision 12 hours/day until pain resolved, or for 6 months. Supplemental opioid was provided by patient-controlled analgesia or orally. Pain was initially evaluated with a Visual Analog Scale, and subsequently by telephone with a Verbal Response Scale and the Pain Disability Index (our primary outcome) after 1 week, 1 month, 3 months, and 6 months

2015 Pain medicine (Malden, Mass.) Controlled trial quality: predicted high

38. Lidocaine

, the plaster may need to be stopped. Resources Twyross R et al. Palliative Care Formulary (Fourth Edition). Palliativedrugs.com. Nottingham, 2011 Electronic Medicines Compendium, Grunenthal Ltd. Lidocaine patches 5% (Versatis ® ). Summary of product characteristics. Updated January 2012. www.medicines.org.uk. References Copyright © 2014 NHSScotland Last Updated: 08 Apr 2015 Created: 14 Nov 2013 Indicates this use is off licence Indicates this medication is associated with QT prolongation Colour codes: Red (...) Lidocaine Scottish Palliative Care Guidelines - Lidocaine Scottish Palliative Care Guidelines search / / / Lidocaine Lidocaine Introduction Lidocaine Plaster in Palliative Care Description Lidocaine is a local anaesthetic effective in some types of such as post-herpetic neuralgia. It is available in a topical plaster formulation, with approximately 3% systemic absorption, reducing the risk of systemic adverse reactions and drug interactions. The use of lidocaine plasters in palliative care has

2015 Scottish Palliative Care Guidelines

39. Evaluation of the Population Pharmacokinetic Properties of Lidocaine and its Metabolites After Long-Term Multiple Applications of a Lidocaine Plaster in Post-Herpetic Neuralgia Patients Full Text available with Trip Pro

was found to be primarily affected by the number of plasters simultaneously applied, i.e., it increased with the number of applied patches, but less than proportionally. No clinically relevant effect of other covariates was found to affect the exposure to lidocaine or its metabolites. As no accumulation was predicted by the model, long-term exposure to lidocaine and its metabolites is not expected to lead to any safety concerns in post-herpetic neuralgia patients. (...) Evaluation of the Population Pharmacokinetic Properties of Lidocaine and its Metabolites After Long-Term Multiple Applications of a Lidocaine Plaster in Post-Herpetic Neuralgia Patients Lidocaine 5% medicated plaster is the first lidocaine containing product for chronic use. As no previous investigations have been conducted to evaluate the population pharmacokinetics of long-term exposure to lidocaine 5% medicated plasters, further insights into the evaluation of the pharmacokinetic properties

2017 European journal of drug metabolism and pharmacokinetics Controlled trial quality: uncertain

40. Injectable Lidocaine Provides Similar Analgesia Compared to Transdermal Lidocaine/Tetracaine Patch for the Incision and Drainage of Skin Abscesses: A Randomized, Controlled Trial. (Abstract)

Injectable Lidocaine Provides Similar Analgesia Compared to Transdermal Lidocaine/Tetracaine Patch for the Incision and Drainage of Skin Abscesses: A Randomized, Controlled Trial. Local anesthesia used for incision and drainage of abscesses is known to be painful.We studied the analgesia provided by a lidocaine/tetracaine patch compared to injectable lidocaine during incision and drainage (I&D) of skin abscesses.This was a prospective, double-blind, randomized, controlled trial carried out (...) in the Emergency Department (ED) of an adult tertiary referral center. Adult patients with a skin abscess in need of I&D were randomized to one of two groups. One group received a lidocaine/tetracaine patch and injectable normal saline for anesthesia. The second group received a placebo patch and injectable 1% lidocaine. A visual analog pain scale was used to record the patient's pain level prior to treatment, during the procedure, and after I&D.There were 20 patients enrolled in the study, including 12

2014 Journal of Emergency Medicine Controlled trial quality: predicted high

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