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Lidocaine Patch

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241. CIRSE Guidelines on Below the Knee Interventions

or resolve vasospasm (Table 4)[21]. The majority of BTK interventions can be performed under local anesthesia. Local analgesics such as lidocaine 1 % may be administered under US guidance to facilitate precise deposition [18]. Mild con- scious sedation (usually up to 50–100 lg of fentanyl and 5 mg of midazolam are suf?cient) may be required in anxious patients or for painful procedures. Data regarding the anti- platelet regime after BTK angioplasty and/or stenting are limited, and most protocols reported (...) can be treated in the same endovascular session via a contralateral retrograde CFA approach. It is also possible to gain ipsilateral retrograde access and invert the sheath, or to use popliteal or pedal access in the same session, depending on the local anatomical situation. The in?ow needs to be corrected before the BTK intervention. When concomitant ipsilateral CFA occlusive disease is present, surgical patch atherectomy and BTK angioplasty can be performed during the same session if an adequate

2013 Cardiovascular and Interventional Radiological Society of Europe

244. Pulmonary Contusion and Flail Chest, Management of

are beyond the scope of this study, and the reader is referred to the EAST guideline on Analgesia in Blunt Thoracic Trauma. [130] However, mention should be made of the increased use of local anesthetic administered by transcutaneous patch (lidocaine 5%, Lidoderm, Endo Pharmaceuticals) since that guideline was published. At this writing, the patch is Food and Drug Administration approved for postherpetic neuralgia, but it has been used “off-label” for other analgesic indications including chronic lower (...) back pain, [131] postlaparoscopic surgical pain, [132] and headache. Ingalls et al. [133] performed an eloquent prospective, randomized controlled trial of lidocaine 5% patch versus placebo for patients with rib fractures. The study was well powered, and the lidocaine patch failed to show sparing of narcotics versus the placebo group. Yet, other work in progress may indicate a narcotic-sparing effect of the patch (unpublished data, work in progress). Vasopressin for PC Arginine vasopressin versus

2012 Eastern Association for the Surgery of Trauma

245. Supporting smoking cessation - a guide for health professionals

and substantial changes in the approved use of nicotine replacement therapy (NRT). Another important development for smoking cessation in Australia has been the listing of nicotine patches on the Pharmaceutical Benefits Scheme (PBS), initially for Aboriginal and Torres Strait Islander people in 2008, and for the general community since February 2011. In recognition of the emerging evidence and the need to keep this guide current, updates were done in June 2012 and 2014. Supporting smoking cessation: a guide (...) ) non-smokers; children under 12 years; hypersensitivity to nicotine or any component of the patch; diseases of the skin that may complicate patch therapy 8 Gum First cigarette >30 minutes after waking 2 mg 8–12 per day >8 (Unscheduled) non-tobacco users; known hypersensitivity to nicotine or any component of the gum; children ( 8 Inhaler >10 cigarettes per day 6–12 cartridges per day >8 (S2) Non-tobacco users; hypersensitivity to nicotine or menthol; children ( 8 (S2) Non-tobacco users

2012 Clinical Practice Guidelines Portal

246. Lidocaine/tetracaine medicated plaster: in minor dermatological and needle puncture procedures. (Abstract)

Lidocaine/tetracaine medicated plaster: in minor dermatological and needle puncture procedures. The lidocaine/tetracaine medicated plaster comprises a lidocaine/tetracaine 70 mg/70 mg patch and a controlled heat-assisted drug delivery pod that increases the diffusion of lidocaine and tetracaine into the dermis. Following a 1-hour application period, systemic absorption of lidocaine or tetracaine from the plaster was minimal. The lidocaine/tetracaine medicated plaster provided effective pain (...) relief for adult (including elderly) patients undergoing minor dermatological procedures and for adult and paediatric patients undergoing vascular access procedures. In randomized, double-blind clinical trials, patient-reported median pain scores were significantly lower with the lidocaine/tetracaine medicated plaster than with an identical plaster containing placebo in patients undergoing minor dermatological or vascular access procedures. Furthermore, patient-reported median pain scores were

2010 Drugs

247. Topical Lidocaine: Predictors of Response in Peripheral Nerve Injury

by (Responsible Party): Danish Pain Research Center Study Details Study Description Go to Brief Summary: The primary purpose is to study the predictive value of preserved nociceptors and large afferent fibers and dynamic mechanical allodynia on the effect of lidocaine patch. The primary outcome measure is the predictive role for these three measures for obtaining a response to lidocaine. A responder is defined as a person with at least a 2-point pain reduction to lidocaine (change in median pain intensity (...) /treatment Phase Neuropathic Pain Drug: Topical lidocaine patch Phase 4 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 24 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Evaluation of Predictors of Response for the Efficacy of Topical Lidocaine Patch (Versatis) on Chronic Neuropathic Pain After Peripheral Nerve Injury Study Start Date : April 2010 Actual

2010 Clinical Trials

248. A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0.3% Lidocain Hydrochloride, Prevelle Silk, for Superficial, Vertical Perioral Lines and Superficial, Horizontal, Lateral Canthal Lines

A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0.3% Lidocain Hydrochloride, Prevelle Silk, for Superficial, Vertical Perioral Lines and Superficial, Horizontal, Lateral Canthal Lines A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0.3% Lidocain Hydrochloride, Prevelle Silk, for Superficial, Vertical Perioral Lines and Superficial, Horizontal, Lateral Canthal Lines - Full Text (...) View - Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0.3% Lidocain Hydrochloride, Prevelle Silk, for Superficial

2010 Clinical Trials

249. Use of Topical Lidocaine to Reduce Pain in Patients With Diabetic Neuropathy

, 2011 Sponsor: Albany Medical College Collaborator: Endo Pharmaceuticals Information provided by: Albany Medical College Study Details Study Description Go to Brief Summary: The purpose of this study is to see if an investigational drug known as the lidocaine 5% patch is safe and effective in reducing the symptoms of diabetic neuropathy, to examine how topical lidocaine affects the nerve endings, and to determine whether treatment with the lidocaine patch can prevent the potential progression (...) Lidocaine (Lidoderm 5% Patch) to Reduce Pain in Patients With Diabetic Neuropathy: Does the Density and Subtype of Sodium Channels Affect Response? Study Start Date : October 2009 Estimated Primary Completion Date : October 2012 Estimated Study Completion Date : October 2013 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Healthy control patients Subjects 18 to 70 years of age, non-diabetic with no nervous

2010 Clinical Trials

250. Acute auditory and vestibular symptoms associated with heat and transdermal lidocaine. (Abstract)

Acute auditory and vestibular symptoms associated with heat and transdermal lidocaine. To describe a case of systemic lidocaine toxicity from the simultaneous use of transdermal patches and a heating pad.Case report and discussion.The focus of this case report are the interesting neuro-otologic signs of central lidocaine toxicity that occurred after a patient fell asleep on a heating pad with his Lidoderm patches in place. Hearing improvement, tinnitus reduction, and severe dizziness and ataxia

2010 Clinical Journal of Pain

251. Topical anesthesia for staple removal from surgical wounds on the knee: a prospective, double-blind, randomized trial. (Abstract)

underwent primary total knee replacement were assigned to an experimental group or control group. One lidocaine patch was applied around the surgical wound for each patient in the experimental group. Alternatively, the adhesive sides of the lidocaine patches were shielded with waterproof films in the control group. A resident peeled off the patch before a single nursing practitioner removed the staples. Pain was assessed with the 10-cm visual analog scale, and a face pain scale-revised was performed (...) with moderate-to-severe pain. The lidocaine patch applied topically around the surgical wound could effectively reduce the pain during the procedure, without remarkable complications such as systemic adverse effects or wound contamination.Copyright © 2017 Elsevier Inc. All rights reserved.

2017 The Journal of surgical research Controlled trial quality: uncertain

252. PRINT Trial (Platelet Rich Injection vs Needle Tenotomy)

, bracing, physical therapy, extracorporal shock wave therapy, anesthetic injections, steroid injections, prolotherapy, nitro patches, surgery and more recently platelet rich plasma, all of which have had conflicting results in the literature. Platelet rich plasma (PRP) is an autologous blood product that contains a high concentration of platelet-derived growth factors that have the potential to enhance healing. In a study by Mishra et al, common extensor tenindosis showed improved pain symptoms (71% vs (...) with approximately an 18 gauge needle with adequate amount of anesthetic (lidocaine) for effective anesthesia. Investigators will keep track of the number of passes through the tendon. Investigators will keep track of the amount and type of anesthetic used Procedure: Percutaneous Needle Tenotomy A sham phlebotomy sample will be drawn on all study participants. Participants in this treatment group will be given local anesthesia with 1% lidocaine and then blinded to the intervention using a blind fold or shielding

2017 Clinical Trials

253. Localized Neuropathic Pain: Topical Treatment Versus Systemic Treatment

, 2019 See Sponsor: University Hospital, Antwerp Information provided by (Responsible Party): Davina Wildemeersch, University Hospital, Antwerp Study Details Study Description Go to Brief Summary: Evaluation of topical treatment with lidocaine 5% patch (daily administration) or capsaicin 8% patch (periodic administration - upon reoccurrence of pain symptoms) in adult patients suffering from localized neuropathic pain (LNP) across a wide variety of etiologies, with a duration between 1 and 12 months (...) (subacute to chronic neuropathic pain (NP)). Condition or disease Intervention/treatment Phase Neuropathic Pain Drug: Lidocaine patch 5% Drug: Capsaicin 8% Patch Drug: Pregabalin Phase 4 Detailed Description: A multicentre, randomized, open-label comparative trial evaluating topical treatment options versus oral systemic treatment in adult patients suffering from localized neuropathic pain (LNP) syndromes. A wide variety of peripheral neuropathic pain syndromes will be included such as post-herpetic

2017 Clinical Trials

254. Impact of Hypno-analgesia on Pain During a Lumbar Puncture for Diagnosis of Alzheimer's Disease

pain management in adults are applied. A transdermal device of lidocaine-pilocaine (type EMLA) is applied 120 minutes before the LP . In addition, an equimolar oxygen-nitrous oxide (MEOPA) mixture could be added. Then, patients benefit from a helping relationship before and during the gesture dedicated to reduce anxiety. Until recently, non-medicinal techniques (relaxation, hypnosis ...) were not recommendedin cases of major anxiety or analgesia deemed insufficient. Many studies have shown (...) , it seems relevantto analyse the effect of this technic in order th test the following hypothesis: hypno-analgesia (non-medicinal technique of care) associated with EMLA patch is more effective than the helping relationship associated with EMLA patch to reduce the pain that may inverse during the LP for diagnosis in patient with mild to moderate stage of Alzheimer's disease. Condition or disease Intervention/treatment Phase Cognitive Impairment Alzheimer Disease Other: Relational care Other: Hypno

2017 Clinical Trials

255. Topical phenytoin for the treatment of neuropathic pain Full Text available with Trip Pro

Topical phenytoin for the treatment of neuropathic pain We developed and tested a new putative analgesic cream, based on the anticonvulsant phenytoin in patients suffering from treatment refractory neuropathic pain. The use of commercial topical analgesics is not widespread due to the facts that capsaicin creams or patches can give rise to side effects, such as burning, and analgesic patches (e.g., lidocaine 5% patches) have complex handling, especially for geriatric patients. Only in a few

2017 Journal of pain research

256. Delayed hemorrhage effect of local anesthesia with epinephrine in the loop electrosurgical excisional procedure Full Text available with Trip Pro

of the population (103, 27.9%) underwent LEEP in the operating room under general anesthesia without injection of local anesthesia. The remaining patients (266, 72.1%) underwent LEEP with local anesthesia (lidocaine HCl 2% with epinephrine 1:100,000) in the office procedure room. Patients given local anesthesia including epinephrine had significantly lower delayed hemorrhage compared to patients with general anesthesia without injection of local anesthesia (P=0.001). Hemostats, such as fibrin glue or patch

2017 Obstetrics & gynecology science

257. Efficacy of Intralesional Triamcinolone Injection in the Treatment of Vitiligo

to Arm Intervention/treatment Experimental: Experimental group All lesions will treated with NBUVB or excimer laser weekly and application of topical tacrolimus ointment twice daily for a total of 12-week period. Intervention: Intralesional injection of triamcinolone acetonide (0.4mg/cc) will be performed weekly. Drug: Triamcinolone acetonide 0.4mg/cc Intralesional injection of dilute triamcinolone acetonide with 2% lidocaine (400mg/20 mL) would be performed to reduce pain when injecting the drug (...) Application of topical tacrolimus ointment twice a day Outcome Measures Go to Primary Outcome Measures : The repigmentation rate (change from baseline) of the vitiliginous patch [ Time Frame: Baseline and 12 weeks ] The degree of repigmentation will be assessed as % from baseline by using a computer program. Secondary Outcome Measures : The adverse effects [ Time Frame: every weeks up to 13 weeks ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate

2017 Clinical Trials

258. The Sphenopalatine Ganglion Block for Post-dural Puncture Headache

downward traction on the meninges with parasympathetic ally mediated reflex vasodilation of the meningeal vessels. The epidural blood patch is currently the gold-standard treatment for postdural puncture headache, however it is an invasive procedure with possible risks and complications including bleeding, infection, pain, hematoma, neurologic complications, and repeat dural puncture. Patients are often offered conservative treatment including medications, bed rest, abdominal binders, and fluids (...) for at least 24 hours prior to being offered an epidural blood patch. Once the decision is made to proceed with a blood patch, it may take several hours before the procedure is performed due to staffing issues. We propose that the sphenopalatine ganglion block, a relatively noninvasive procedure which has been used by neurologists as a treatment for a variety of types of headaches, may play a role in the treatment of postdural puncture headache in the obstetric population.The sphenopalatine ganglion

2017 Clinical Trials

259. Kybella With Triamcinolone

by (Responsible Party): Goldman, Butterwick, Fitzpatrick and Groff Study Details Study Description Go to Brief Summary: This study is to evaluate the efficacy, edema and pain associated with Kybella(TM) injections of the upper neck in the treatment of submental fat with varying low concentrations of triamcinolone acetonide plus low doses of lidocaine. Condition or disease Intervention/treatment Phase Adiposity Drug: Injectable sodium deoxycholate Combination Product: Injectable sodium deoxycholate (...) mg/cm2 of Kybella(TM) with 0.2 mL of 1% lidocaine with no epinephrine plus 0.2cc saline to the non-TMC group to maintain equal concentrations in each injection so that the final Kybella concentration per vial will be 10mg/1.2mls or 1.6mg per 0.2 cc injection point will be delivered in up to 50 injections spaced 1.0 cm apart at 0.2 mL/injection for a total maximal dose of up to 100 mg of SDOC. Group 2 (10 patients per site): Kybella(TM)+TMC at 1.0 mg/mL: 2.0 mL of 2 mg/cm2 of Kybella(TM

2017 Clinical Trials

260. Midfacial Product Selection

Intervention/treatment Active Comparator: Group A Poor structural support/volume (atrophy of soft tissues, leading to loss of projection) with adequate skin envelope (normal or thick skin). Treated with Restylane Lyft. Device: Restylane Lyft Restylane® Lyft is a sterile gel of hyaluronic acid with lidocaine generated by Streptococcus species of bacteria, chemically cross-linked with BDDE (the cross linker), stabilized and suspended in phosphate buffered saline at pH=7 and concentration of 20 mg/mL. Lyft (...) to appear for all scheduled follow-up visits; No previous facial fillers for a period of 12 months prior to this study; No previous facial fillers in the mid-face for 18 months prior to this study; Capable of providing informed consent. Exclusion Criteria: Current Pregnancy or lactation [sexually active women of childbearing age must agree to use medically acceptable methods of contraception for the duration of this study (e.g., oral contraceptives, condoms, intrauterine device, shot/injection, patch

2017 Clinical Trials

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