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121. Safety and PK Study of Ha44 Gel Under Maximal Use Conditions for Treatment of Head Lice Infestation

Safety and PK Study of Ha44 Gel Under Maximal Use Conditions for Treatment of Head Lice Infestation Safety and PK Study of Ha44 Gel Under Maximal Use Conditions for Treatment of Head Lice Infestation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Safety and PK Study of Ha44 Gel Under Maximal Use Conditions for Treatment of Head Lice Infestation The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01907490 Recruitment Status : Completed First Posted : July 25, 2013 Results First Posted : February 9

2013 Clinical Trials

122. Amazonian Head Lice-Specific Genotypes Are Putatively Pre-Columbian. Full Text available with Trip Pro

Amazonian Head Lice-Specific Genotypes Are Putatively Pre-Columbian. Head and body lice are strict obligate human ectoparasites with three mitochondrial phylotypes (A, B, and C). Using molecular methods for genotyping lice (Cytochrome b and multi-spacer typing), and comparing our results with all the sequences of human lice that were genotyped previously, we assessed the presence of a specific American genotype that most likely predates the Columbian era in head lice collected from Amazonia.

2013 American Journal of Tropical Medicine & Hygiene

123. Assessment of the safety and efficacy of three concentrations of topical ivermectin lotion as a treatment for head lice infestation. (Abstract)

Assessment of the safety and efficacy of three concentrations of topical ivermectin lotion as a treatment for head lice infestation. Ivermectin is a broad-spectrum parasiticide in widespread systemic use, including as an off-label treatment for head lice infestation. The potential of the topical use of ivermectin as a treatment for head lice infestation was suggested by an in vitro report of a novel lotion formulation.This study investigated the relative effectiveness of three ivermectin lotion (...) concentrations (0.15, 0.25, and 0.5%) compared with vehicle placebo in eliminating head lice infestation.In this randomized, blinded study, 78 head lice-infested subjects, aged 2-62 years, received a single, 10-minute application of product on day 1. Evaluations were completed at two and six hours post-application, and on days 2, 8 (±1), and 15 (+2). Safety was assessed according to the evaluations of trained observers and adverse event (AE) reports. Efficacy was assessed according to scalp and hair

2013 International journal of dermatology Controlled trial quality: uncertain

124. Borrelia recurrentis in Head Lice, Ethiopia. Full Text available with Trip Pro

Borrelia recurrentis in Head Lice, Ethiopia. Since the 1800s, the only known vector of Borrelia recurrentis has been the body louse. In 2011, we found B. recurrentis DNA in 23% of head lice from patients with louse-borne relapsing fever in Ethiopia. Whether head lice can transmit these bacteria from one person to another remains to be determined.

2013 Emerging Infectious Diseases

125. Head lice: the feelings people have. (Abstract)

Head lice: the feelings people have. Head lice are a source of amusement for outsiders and an embarrassing nuisance to those who have to deal with them. Our study collected the emotions experienced by people dealing with head lice. An area with extremely sparse literature, our purpose is to inform the development of more effective programs to control head lice.We asked "what were your feelings upon discovery of head lice?" as part of a study exploring the experience of those treating head lice (...) . A short questionnaire was available via the authors' head lice information internet site. A total of 294 eligible responses were collected over several months and analyzed, supported by QSR N6.The predominantly female (90 · 9%) respondents were residents of Australia (56 · 1%), USA (20 · 4%), Canada (7 · 2%), or UK (4 · 4%), and working full-time (43·0%) or part-time (34 · 2%). Reactions and feelings fell into three categories: strong (n = 320; 79% of all stated emotions), mediocre (n = 56; 20

2013 International Journal of Dermatology

126. A New Method of Controlling the Head Louse Full Text available with Trip Pro

A New Method of Controlling the Head Louse 20784179 2011 04 04 2011 04 04 0007-1447 1 4240 1942 Apr 11 British medical journal Br Med J A New Method of Controlling the Head Louse. 464-6 Busvine J R JR Buxton P A PA eng Journal Article England Br Med J 0372673 0007-1447 2010 8 27 6 0 1942 4 11 0 0 1942 4 11 0 1 ppublish 20784179 PMC2160636

1942 British medical journal

127. Sea lice, Lepeophtheirus salmonis (Krøyer 1837), infected Atlantic salmon (Salmo salar L.) are more susceptible to infectious salmon anemia virus. Full Text available with Trip Pro

Sea lice, Lepeophtheirus salmonis (Krøyer 1837), infected Atlantic salmon (Salmo salar L.) are more susceptible to infectious salmon anemia virus. The role of parasitic sea lice (Siphonostomatoida; Caligidae), especially Lepeophtheirus salmonis, in the epidemiology of Infectious Salmon Anemia Virus (ISAv) has long been suspected. The epidemiological studies conducted during the 1998 major Infectious Salmon Anaemia (ISA) outbreak in Scotland demonstrated a strong correlation between sea lice (...) presence and ISAv positive sites or subsequent clinical outbreaks of ISA. The question posed from this observation was "do sea lice infestations on Atlantic salmon make them more susceptible to viral infections?" This study investigated the role that sea lice infestations have on the severity of ISAv infections and disease mortality in experimental populations of farmed Atlantic salmon (Salmo salar). A series of experiments was carried out that investigated the potential of sea lice to modify

2019 PLoS ONE

128. Correction: Sea lice, Lepeophtheirus salmonis (Krøyer 1837), infected Atlantic salmon (Salmo salar L.) are more susceptible to infectious salmon anemia virus. Full Text available with Trip Pro

Correction: Sea lice, Lepeophtheirus salmonis (Krøyer 1837), infected Atlantic salmon (Salmo salar L.) are more susceptible to infectious salmon anemia virus. [This corrects the article DOI: 10.1371/journal.pone.0209178.].

2019 PLoS ONE

129. Dermoscopy of pediculosis pubis Full Text available with Trip Pro

Dermoscopy of pediculosis pubis 29892659 2018 11 14 2352-5126 4 2 2018 Mar JAAD case reports JAAD Case Rep Dermoscopy of pediculosis pubis. 168-169 10.1016/j.jdcr.2017.08.011 Li Lin L Department of Dermatology, Chengdu Second People's Hospital, Chengdu, China. Liu Xueying X Department of Dermatology, Chengdu Second People's Hospital, Chengdu, China. Xu Lei L Department of Dermatology, Chengdu Second People's Hospital, Chengdu, China. Lu Yonghong Y Department of Dermatology, Chengdu Second

2018 JAAD Case Reports

130. Topical Ivermectin Lotion for Head Lice

Topical Ivermectin Lotion for Head Lice Rotation Prep | NEJM Resident 360 Social Login Email Login Log in via Email Create Your Account We will not share your email with anyone. Password must be at least 8 characters. Show or Hide the password you are typing. Request to Join has invited you to join this group Your browser does not support video tags Welcome! NEJM Resident 360 helps you prepare for your next rotation quickly and efficiently, provides support for coping with the pressures

2012 Now@NEJM

131. Antioxidant effect of mogrosides against oxidative stress induced by palmitic acid in mouse insulinoma NIT-1 cells Full Text available with Trip Pro

Antioxidant effect of mogrosides against oxidative stress induced by palmitic acid in mouse insulinoma NIT-1 cells Excessive oxidative stress in pancreatic β cells, caused by glucose and fatty acids, is associated with the pathogenesis of type 2 diabetes. Mogrosides have shown antioxidant and antidiabetic activities in animal models of diabetes, but the underlying mechanisms remain unclear. This study evaluated the antioxidant effect of mogrosides on insulinoma cells under oxidative stress (...) caused by palmitic acid, and investigated the underlying molecular mechanisms. Mouse insulinoma NIT-1 cells were cultured in medium containing 0.75 mM palmitic acid, mimicking oxidative stress. The effects of 1 mM mogrosides were determined with the dichlorodihydrofluorescein diacetate assay for intracellular reactive oxygen species (ROS) and FITC-Annexin V/PI assay for cell apoptosis. Expression of glucose transporter-2 (GLUT2) and pyruvate kinase was determined by semi-quantitative reverse

2013 Brazilian Journal of Medical and Biological Research

132. Pubic lice

Pubic lice Pubic lice - NICE CKS Share Pubic lice: Summary Pubic lice infestation (pediculosis pubis) is caused by an obligate, blood-sucking ectoparasite — Phthirus pubis . Transmission of pubic lice most often occurs through sexual or non-sexual close body contact but lice may also crawl onto a host from infested materials such as bedding, clothing or towels. Children with pubic lice infestation are usually thought to have acquired this innocently, but the possibility of sexual abuse should (...) ectoparasite — Phthirus pubis . P. pubis is also known as the crab louse due to pincer-like claws on its second and third pairs of legs. These claws allow the louse to attach to coarse body hair, most often in the pubic area, but also occasionally on the chest, armpits, eyelashes and face. The pubic louse is grey-brown in colour and about 2 mm long and can only survive for 24–48 hours off the human host. Female lice live for 1–3 months and over this time can lay up to 300 yellow/white eggs which

2018 NICE Clinical Knowledge Summaries

133. The Atlantic salmon (Salmo salar) antimicrobial peptide cathelicidin-2 is a molecular host-associated cue for the salmon louse (Lepeophtheirus salmonis) Full Text available with Trip Pro

The Atlantic salmon (Salmo salar) antimicrobial peptide cathelicidin-2 is a molecular host-associated cue for the salmon louse (Lepeophtheirus salmonis) Chemical signals are a key element of host-parasite interactions. In marine ecosystems, obligate ectoparasites, such as sea lice, use chemical cues and other sensory signals to increase the probability of encountering a host and to identify appropriate hosts on which they depend to complete their life cycle. The chemical compounds that underlie (...) host identification by the sea lice are not fully described or characterized. Here, we report a novel compound - the Atlantic salmon (Salmo salar) antimicrobial peptide cathelicidin-2 (Cath-2) - that acts as an activation cue for the marine parasitic copepod Lepeophtheirus salmonis. L. salmonis were exposed to 0, 7, 70 and 700 ppb of Cath-2 and neural activity, swimming behaviour and gene expression profiles of animals in response to the peptide were evaluated. The neurophysiological, behavioural

2018 Scientific reports

134. Tick-, Flea-, and Louse-Borne Diseases of Public Health and Veterinary Significance in Nigeria Full Text available with Trip Pro

Tick-, Flea-, and Louse-Borne Diseases of Public Health and Veterinary Significance in Nigeria Mosquito-borne diseases are common high-impact diseases in tropical and subtropical areas. However, other non-mosquito vector-borne pathogens (VBPs) may share their geographic distribution, seasonality, and clinical manifestations, thereby contributing their share to the morbidity and mortality caused by febrile illnesses in these regions. The purpose of this work was to collect and review existing (...) information and identify knowledge gaps about tick, flea-, and louse-borne diseases of veterinary and public health significance in Nigeria. Full-length articles about VBPs were reviewed and relevant information about the vectors, their hosts, geographic distribution, seasonality, and association(s) with human or veterinary diseases was extracted. Specific laboratory tools used for detection and identification of VBPs in Nigeria were also identified. A total of 62 original publications were examined

2018 Tropical Medicine and Infectious Disease

135. Deltamethrin resistance in the salmon louse, Lepeophtheirus salmonis (Krøyer): Maternal inheritance and reduced apoptosis Full Text available with Trip Pro

Deltamethrin resistance in the salmon louse, Lepeophtheirus salmonis (Krøyer): Maternal inheritance and reduced apoptosis Resistance towards deltamethrin (DMT) in the crustacean ectoparasite Lepeophtheirus salmonis (Caligidae) is a problem on fish farms lining the North Atlantic Ocean. Two Norwegian strains with different susceptibility towards DMT were crossed in the parental generation (P0), females from a sensitive strain were crossed with males from a resistant strain and vice versa (...) , including SNPs in two cytochrome C oxidase subunits (COX1 and COX3) and two subunits of the NADH dehydrogenase complex (ND1 and ND5) previously linked to DMT resistance in the salmon louse. Differential expression analysis between the sensitive and resistant strain revealed strain effect in seven out of twelve mt-genes. The current study also show that DNA fragmentation (indicating apoptosis) was affected by DMT exposure in skeletal muscle tissue and that resistant parasites undergo less apoptosis than

2018 Scientific reports

136. Maternal inheritance of deltamethrin resistance in the salmon louse Lepeophtheirus salmonis (Krøyer) is associated with unique mtDNA haplotypes. Full Text available with Trip Pro

Maternal inheritance of deltamethrin resistance in the salmon louse Lepeophtheirus salmonis (Krøyer) is associated with unique mtDNA haplotypes. Parasitic infections by the salmon louse, Lepeophtheirus salmonis (Krøyer), cause huge economic damage in salmon farming in the northern hemisphere, with combined treatment costs and production losses in 2014 having been estimated at US$ 350 million for Norway (annual production 1.25 million tonnes). The control of L. salmonis relies significantly

2017 PLoS ONE

137. Genetic fingerprinting of salmon louse (Lepeophtheirus salmonis) populations in the North-East Atlantic using a random forest classification approach Full Text available with Trip Pro

Genetic fingerprinting of salmon louse (Lepeophtheirus salmonis) populations in the North-East Atlantic using a random forest classification approach Caligid sea lice represent a significant threat to salmonid aquaculture worldwide. Population genetic analyses have consistently shown minimal population genetic structure in North Atlantic Lepeophtheirus salmonis, frustrating efforts to track louse populations and improve targeted control measures. The aim of this study was to test the power (...) of reduced representation library sequencing (IIb-RAD sequencing) coupled with random forest machine learning algorithms to define markers for fine-scale discrimination of louse populations. We identified 1286 robustly supported SNPs among four L. salmonis populations from Ireland, Scotland and Northern Norway. Only weak global structure was observed based on the full SNP dataset. The application of a random forest machine-learning algorithm identified 98 discriminatory SNPs that dramatically improved

2018 Scientific reports

138. Outbreak of Louse-Borne Relapsing Fever among Urban Dwellers in Arsi Zone, Central Ethiopia, from July to November 2016. Full Text available with Trip Pro

Outbreak of Louse-Borne Relapsing Fever among Urban Dwellers in Arsi Zone, Central Ethiopia, from July to November 2016. We report epidemiological and clinical aspects of an outbreak of louse-borne relapsing fever (LBRF) in Asella in Arsi Zone, central Ethiopia, from July to November 2016. A total of 63 LBRF cases were reported. The overall case fatality rate was 13% among treated patients. In this article, the first-line epidemiological assessment, individual prevention and control measures

2018 American Journal of Tropical Medicine & Hygiene

139. Ionotropic receptors signal host recognition in the salmon louse (Lepeophtheirus salmonis, Copepoda). Full Text available with Trip Pro

and settlement of lice larvae was achieved on Atlantic salmon. More remarkably, knock down of the IRs changed the host specificity of the salmon louse and lice larvae settled at a significant rate on host that the wild type lice rejected within minutes. To our knowledge, this has never before been demonstrated for any metazoan parasite. Our results show that the parasites are able to identify the host quickly upon settlement, settle and initiate the parasitic life style if they are on the right host (...) Ionotropic receptors signal host recognition in the salmon louse (Lepeophtheirus salmonis, Copepoda). A remarkable feature of many parasites is a high degree of host specificity but the mechanisms behind are poorly understood. A major challenge for parasites is to identify and infect a suitable host. Many species show a high degree of host specificity, being able to survive only on one or a few related host species. To facilitate transmission, parasite's behavior and reproduction has been fine

2017 PLoS ONE

140. Correction: Evaluation of a national operational salmon lice monitoring system-From physics to fish. Full Text available with Trip Pro

Correction: Evaluation of a national operational salmon lice monitoring system-From physics to fish. [This corrects the article DOI: 10.1371/journal.pone.0201338.].

2018 PLoS ONE

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