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1. Effect of a New Head Lice Treatment, Abametapir Lotion, 0.74%, on Louse Eggs: A Randomized, Double-Blind Study. Full Text available with Trip Pro

Effect of a New Head Lice Treatment, Abametapir Lotion, 0.74%, on Louse Eggs: A Randomized, Double-Blind Study. Few head lice treatments have demonstrated effectiveness against louse eggs. Abametapir, a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development. In this double-blind, phase 2 study, 50 subjects aged ≥3 years with active head lice infestation were randomized to receive a single treatment of abametapir lotion, 0.74%, or vehicle (...) %). Abametapir lotion, 0.74%, demonstrated significant ovicidal activity against head lice eggs with a single application.

2019 Global pediatric health Controlled trial quality: uncertain

2. Pediculosis capitis

are not effective and should be abandoned. Definition The head louse ( Pediculus humanus capitis ) is an obligate ectoparasite that lives on human beings and feeds on human blood. Burgess IF, Silverston P. Head lice. Clin Evid (Online). January 2015. http://clinicalevidence.bmj.com (last accessed 2 November 2016). http://clinicalevidence.bmj.com/ceweb/conditions/skd/1703/1703.jsp http://www.ncbi.nlm.nih.gov/pubmed/25587918?tool=bestpractice.com Head lice infestation (pediculosis capitis) mainly affects those (...) Pediculosis capitis Pediculosis capitis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Pediculosis capitis Last reviewed: February 2019 Last updated: June 2018 Summary Head lice infestations are associated with little morbidity but cause strain and distress to parents, carers, and teachers. Effective pediculicides exist, but head lice in some areas have developed resistance to products with a neurotoxic mode

2018 BMJ Best Practice

3. Efficacy of herbal shampoo base on native plant against head lice (Pediculus humanus capitis De Geer, Pediculidae: Phthiraptera) in vitro and in vivo in Thailand. (Abstract)

Efficacy of herbal shampoo base on native plant against head lice (Pediculus humanus capitis De Geer, Pediculidae: Phthiraptera) in vitro and in vivo in Thailand. Head lice infestation (or pediculosis) is an important public health problem in Thailand, especially in children between the ages 5 and 11 years. Head lice resistance is increasing, chemical pediculicides have lost their efficacy, and, therefore, alternative pediculicides such as herbal shampoos have been proposed to treat head lice (...) infestation. Thus, the present study investigated the efficacy of three herbal shampoos based on native plants in Thailand (Acorus calamus Linn., Phyllanthus emblica Linn., and Zanthoxylum limonella Alston) against head lice and compared them with carbaryl shampoo (Hafif shampoo, 0.6% w/v carbaryl), malathion shampoo (A-Lice shampoo, 1.0% w/v malathion), and commercial shampoos (Babi Mild Natural' N Mild and Johnson's baby shampoo) in order to assess their in vitro and in vivo efficacy. For in vitro study

2014 Parasitology research Controlled trial quality: uncertain

4. Orientation of Head Lice on Human Hosts, and Consequences for Transmission of Pediculosis: The Head Lice Movement Studies Full Text available with Trip Pro

Orientation of Head Lice on Human Hosts, and Consequences for Transmission of Pediculosis: The Head Lice Movement Studies We performed head lice movement studies to elucidate factors influencing orientation and movement of head lice. Studies included observation of lice movements on hand and forearm at different positions of the upper limb; movements exposed to unshaved and shaved forearm; and movements with and without antennae. In 57 of 60 (95.0%) observations while holding the hand down (...) not move, 5 (20%) walked proximal, and 3 (12%) distal. Transmission of head lice may not only occur by head-to-head contact, but also via head-to-body contact, with movement to the head against gravitational pull. Surface factors of hand and forearm may be important in orientation for lice, in addition to gravity. Movement of lice against gravity is not governed by organs in the antennae.

2017 Tropical Medicine and Infectious Disease

5. Molecular survey of the head louse Pediculus humanus capitis in Thailand and its potential role for transmitting Acinetobacter spp. Full Text available with Trip Pro

Molecular survey of the head louse Pediculus humanus capitis in Thailand and its potential role for transmitting Acinetobacter spp. Head louse infestation, which is caused by Pediculus humanus capitis, occurs throughout the world. With the advent of molecular techniques, head lice have been classified into three clades. Recent reports have demonstrated that pathogenic organisms could be found in head lice. Head lice and their pathogenic bacteria in Thailand have never been investigated (...) . In this study, we determined the genetic diversity of head lice collected from various areas of Thailand and demonstrated the presence of Acinetobacter spp. in head lice.Total DNA was extracted from 275 head louse samples that were collected from several geographic regions of Thailand. PCR was used to amplify the head louse COI gene and for detection of Bartonella spp. and Acinetobacter spp. The amplified PCR amplicons were cloned and sequenced. The DNA sequences were analyzed via the neighbor-joining

2015 Parasites & vectors

7. Head lice infestations: A clinical update

Head lice infestations: A clinical update Head lice ( Pediculus humanus capitis ) infestations are not a primary health hazard or a vector for disease, but they are a societal problem with substantial costs. Diagnosis of head lice infestation requires the detection of a living louse. Although pyrethrins and permethrin remain first-line treatments in Canada, isopropyl myristate/ST-cyclomethicone solution and dimeticone can be considered as second-line therapies when there is evidence (...) of treatment failure. Keywords: Dimeticone solution; Head lice; Infestations; Isopropyl myristate/cyclomethicone solution; Permethrin; Pyrethrin.

2018 Canadian Paediatric Society

8. Acute poisoning in a child following topical treatment of head lice (pediculosis capitis) with an organophosphate pesticide Full Text available with Trip Pro

Acute poisoning in a child following topical treatment of head lice (pediculosis capitis) with an organophosphate pesticide This is a case report of acute organophosphate poisoning in a child treated with topical application of Diazinon-60 (WHO Class II toxicity) for head lice (pediculosis capitis). The patient presented with neurological symptoms and signs. After emergency respiratory and circulatory resuscitation the patient underwent dermal decontamination and was treated with atropine, high (...) flow oxygen and pralidoxime. Scanning electron micrographs of scalp hair specimens revealed both viable and empty head lice nits (lice eggs that attach to the hair shaft). The patient was hospitalized for seven days and discharged after full recovery. The case highlights the importance of raising the awareness of health workers and the community about the danger of misusing pesticides for the treatment of head lice.

2016 Sudanese journal of paediatrics

9. Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarettes

undergoing treatment came into contact with a naked flame, resulting in very serious burns. Pharmacists should encourage parents, caregivers, and people with head lice to read the instructions carefully for all headlice eradication products. Article citation: Drug Safety Update volume 11 issue 8; March 2018: 3. Published 8 March 2018 Related content Explore the topic Is this page useful? Thank you for your feedback Help us improve GOV.UK Don’t include personal or financial information like your National (...) Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarettes Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarettes - GOV.UK GOV.UK uses cookies to make the site simpler. Search Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarettes Pharmacists

2018 MHRA Drug Safety Update

10. Treatment of Pediculosis (Head Lice) in Senegal

Treatment of Pediculosis (Head Lice) in Senegal Treatment of Pediculosis (Head Lice) in Senegal - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Treatment of Pediculosis (Head Lice) in Senegal (IVERAZITH (...) Details Study Description Go to Brief Summary: This is a prospective single-arm interventional study evaluating Therapeutic efficacy of a combination of two pharmaceutical drugs, Azithromycin (AZIT) and Ivermectin (IVER) administered orally in the treatment of head lice infestations. In case of persistence of lice and / or nits on day 7, a second oral administration of combination Azithromycin + Ivermectin will be considered. The duration of the study period is 4 months, ie 1 month and ½ of inclusion

2018 Clinical Trials

11. Expansion of the Knockdown Resistance Frequency Map for Human Head Lice (Phthiraptera: Pediculidae) in the United States Using Quantitative Sequencing Full Text available with Trip Pro

Expansion of the Knockdown Resistance Frequency Map for Human Head Lice (Phthiraptera: Pediculidae) in the United States Using Quantitative Sequencing Pediculosis is a prevalent parasitic infestation of humans, which is increasing due, in part, to the selection of lice resistant to either the pyrethrins or pyrethroid insecticides by the knockdown resistance (kdr) mechanism. To determine the extent and magnitude of the kdr-type mutations responsible for this resistance, lice were collected from (...) 138 collection sites in 48 U.S. states from 22 July 2013 to 11 May 2015 and analyzed by quantitative sequencing. Previously published data were used for comparisons of the changes in the frequency of the kdr-type mutations over time. Mean percent resistance allele frequency (mean % RAF) values across the three mutation loci were determined from each collection site. The overall mean % RAF (±SD) for all analyzed lice was 98.3 ± 10%. 132/138 sites (95.6%) had a mean % RAF of 100%, five sites (3.7

2016 Journal of medical entomology

12. A new species of sucking louse Hoplopleura villosissima n. sp. (Psocodea: Phthiraptera: Hoplopleuridae) and a new host record of the spiny rat louse Polyplax spinulosa Burmeister, 1839 (Psocodea: Phthiraptera: Polyplacidae) from the long-haired rat Rattus Full Text available with Trip Pro

A new species of sucking louse Hoplopleura villosissima n. sp. (Psocodea: Phthiraptera: Hoplopleuridae) and a new host record of the spiny rat louse Polyplax spinulosa Burmeister, 1839 (Psocodea: Phthiraptera: Polyplacidae) from the long-haired rat Rattus The sucking louse fauna of endemic Australian rodents has been under-studied for decades. Sixty-five species of native rodents have been recorded in Australia. However, only 11 species of lice have been reported from 11 species of endemic (...) Australian rodents.We describe a new species of sucking louse, Hoplopleura villosissima Wang (Psocodea: Phthiraptera: Hoplopleuridae), and report a new host record of the spiny rat louse, Polyplax spinulosa Burmeister, 1839 (Psocodea: Phthiraptera: Polyplacidae), from the long-haired rat, Rattus villosissimus Waite (Rodentia: Muridae), which is endemic to Australia.This study is the first record of sucking louse from R. villosissimus and the first record of a species of Polyplax Enderlein, 1904 from

2018 Parasites & vectors

13. Safety, Efficacy, and Physicochemical Characterization of Tinospora crispa Ointment: A Community-Based Formulation against Pediculus humanus capitis Full Text available with Trip Pro

Safety, Efficacy, and Physicochemical Characterization of Tinospora crispa Ointment: A Community-Based Formulation against Pediculus humanus capitis The high prevalence of pediculosis capitis, commonly known as head lice (Pediculus humanus capitis) infestation, has led to the preparation of a community-based pediculicidal ointment, which is made of common household items and the extract of Tinospora crispa stem. The present study aimed to evaluate the safety, efficacy, and physicochemical

2017 The Korean journal of parasitology

14. Head lice infestations: A clinical update

Head lice infestations: A clinical update Head lice ( Pediculus humanus capitis ) infestations are not a primary health hazard or a vector for disease, but they are a societal problem with substantial costs. Diagnosis of head lice infestation requires the detection of a living louse. Although pyrethrins and permethrin remain first-line treatments in Canada, isopropyl myristate/ST-cyclomethicone solution and dimeticone can be considered as second-line therapies when there is evidence (...) of treatment failure. Keywords: Dimeticone solution; Head lice; Infestations; Isopropyl myristate/cyclomethicone solution; Permethrin; Pyrethrin.

2016 Canadian Paediatric Society

15. Correction: Efficacy of Peer Education for Adopting Preventive Behaviors against Head Lice Infestation in Female Elementary School Students: A Randomised Controlled Trial. Full Text available with Trip Pro

Correction: Efficacy of Peer Education for Adopting Preventive Behaviors against Head Lice Infestation in Female Elementary School Students: A Randomised Controlled Trial. [This corrects the article DOI: 10.1371/journal.pone.0169361.].

2019 PLoS ONE Controlled trial quality: uncertain

16. Peripilar keratin cysts or pseudonits: When nits are not nits! Full Text available with Trip Pro

. Government Medical College, Kangra, Tanda 176 001, Himachal Pradesh, India. eng Case Reports Journal Article India Indian J Med Res 0374701 0971-5916 5688UTC01R Tretinoin IM Adult Animals Female Humans India Lice Infestations diagnosis drug therapy pathology Pediculus drug effects pathogenicity Tretinoin administration & dosage Young Adult 2017 9 27 6 0 2017 9 28 6 0 2018 7 10 6 0 ppublish 28948965 IndianJMedRes_2017_145_5_700_215553 10.4103/ijmr.IJMR_2029_15 PMC5644309 (...) Peripilar keratin cysts or pseudonits: When nits are not nits! 28948965 2018 07 09 2018 07 09 0971-5916 145 5 2017 May The Indian journal of medical research Indian J. Med. Res. Peripilar keratin cysts or pseudonits: When nits are not nits! 700 10.4103/ijmr.IJMR_2029_15 Rawat Ritu R Department of Dermatology, Venereology & Leprosy, Dr. R. P. Government Medical College, Kangra, Tanda 176 001, Himachal Pradesh, India. Mahajan Vikram K VK Department of Dermatology, Venereology & Leprosy, Dr. R. P

2017 The Indian journal of medical research

17. Randomized, investigator-blinded, controlled clinical study with lice shampoo (Licener®) versus dimethicone (Jacutin® Pedicul Fluid) for the treatment of infestations with head lice. (Abstract)

Randomized, investigator-blinded, controlled clinical study with lice shampoo (Licener®) versus dimethicone (Jacutin® Pedicul Fluid) for the treatment of infestations with head lice. The present clinical trial was conducted to obtain additional data for the safety and efficacy of a head lice shampoo that is free of silicone compared with an anti-head lice product containing dimethicone. Both products act by a physical mode of action. This randomized, investigator-blinded, controlled clinical (...) study was conducted between July and November 2016 in households of two villages (Abou Rawash and Shandalat) in Egypt. Children older than 2 years with an active head lice infestation were treated with either a shampoo-based head lice treatment containing neem extract (Licener®) or dimethicone (Jacutin® Pedicul Fluid) on day 1 and additionally on day 9. Assessment for living lice by combing was conducted before and 1-2 h after treatment and on days 5 and 13. The main objective was to demonstrate

2017 Parasitology research Controlled trial quality: uncertain

18. Clinical studies evaluating abametapir lotion, 0.74%, for the treatment of head louse infestation Full Text available with Trip Pro

months and older to compare the effectiveness of abametapir lotion versus vehicle control for eliminating head louse infestations without nit combing. Abametapir lotion was applied to dry hair for 10 minutes on day 0 and then rinsed with water. The primary endpoint was the proportion of index subjects (youngest household member with ≥ 3 live lice at screening) in the intent-to-treat population who were louse free at all follow-up visits through day 14. Older household members with one or more live (...) Clinical studies evaluating abametapir lotion, 0.74%, for the treatment of head louse infestation There is a need for better control of head louse infestations. Abametapir is an inhibitor of metalloproteinases critical for louse survival and egg development. The efficacy of abametapir lotion, 0.74%, was assessed for its ability to clear head louse infestations after a single application.Two randomized, double-blind, multicenter, vehicle-controlled studies were conducted in subjects aged 6

2018 Pediatric dermatology Controlled trial quality: uncertain

19. Wet combing for head lice

Media Releases 2013 Media Releases 2012 Media Releases Search Wet combing: head lice Wet combing: head lice Introduction Half of the people infested with lice do not scratch; all people in contact with an affected person should be manually checked for lice. Intervention Manual (condition and comb or wet comb) removal using the Bug Buster® kit, Quit Nits Combing Solution® or other head lice comb. Indication Head lice ( Pediculosis capitis) infestation. Suitable for insecticide resistant infestations (...) Wet combing for head lice RACGP - Wet combing for head lice Search Become a student member today for free and be part of the RACGP community A career in general practice Starting the GP journey Enrolments for the 2019.1 OSCE FRACGP exams closing 29 March 2019 Fellowship FRACGP exams Research Practice Experience Program is a self-directed education program designed to support non vocationally registered doctors on their pathway to RACGP Fellowship Fellowship International graduates FRACGP exams

2013 Handbook of Non-Drug interventions (HANDI)

20. Head lice: Dimeticone is the pediculicide of choice

Pyrethroids are no longer the first-choice treatment for head lice: they are losing effectiveness and may be toxic in the long term. Dimeticone is a better choice, because it has few known adverse effects and proven efficacy. Full review (4 pages) available for download by subscribers. Abstract Infestation of the scalp by head lice , or pediculosis, is a common, unpleasant but harmless parasitosis. For patients with pediculosis , which topical treatment eradicates the parasites effectively while causing (...) Head lice: Dimeticone is the pediculicide of choice Prescrire IN ENGLISH - Spotlight ''Head lice: Dimeticone is the pediculicide of choice '', 1 July 2014 {1} {1} {1} | | > > > Head lice: Dimeticone is the pediculicide of choice Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Head lice: Dimeticone is the pediculicide of choice FEATURED REVIEW

2014 Prescrire

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