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1. Ivermectin for Parasitic Skin Infections of Lice: A Review of Comparative Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Ivermectin for Parasitic Skin Infections of Lice: A Review of Comparative Clinical Effectiveness, Cost-Effectiveness, and Guidelines Ivermectin for Parasitic Skin Infections of Lice: A Review of Comparative Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Ivermectin for Parasitic Skin Infections of Lice: A Review of Comparative Clinical Effectiveness, Cost-Effectiveness, and Guidelines Ivermectin for Parasitic Skin Infections of Lice: A Review (...) of Comparative Clinical Effectiveness, Cost-Effectiveness, and Guidelines Last updated: May 14, 2019 Project Number: RC1115-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the comparative clinical effectiveness of oral versus topical ivermectin for parasitic skin infections of lice? What is the comparative clinical effectiveness of oral ivermectin versus pediculicides for parasitic skin infections of lice? What is the comparative

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

3. Head lice infestations: A clinical update

Head lice infestations: A clinical update Head lice ( Pediculus humanus capitis ) infestations are not a primary health hazard or a vector for disease, but they are a societal problem with substantial costs. Diagnosis of head lice infestation requires the detection of a living louse. Although pyrethrins and permethrin remain first-line treatments in Canada, isopropyl myristate/ST-cyclomethicone solution and dimeticone can be considered as second-line therapies when there is evidence (...) of treatment failure. Keywords: Dimeticone solution; Head lice; Infestations; Isopropyl myristate/cyclomethicone solution; Permethrin; Pyrethrin.

2018 Canadian Paediatric Society

4. Annotated checklist of fleas (Insecta: Siphonaptera) and lice (Insecta: Anoplura) associated with rodents in Iran, with new reports of fleas and lice. (PubMed)

Annotated checklist of fleas (Insecta: Siphonaptera) and lice (Insecta: Anoplura) associated with rodents in Iran, with new reports of fleas and lice. Rodent species reported from Iran are subject of several studies, but the fauna called ectoparasite, infesting the rodents, along with their epidemic effects, are poorly known. In this study, ectoparasitic insect fauna of rodents found across the Iran were studied, to generate an annotated checklist of fleas and lice species.Several field (...) Calomyscidae, Cricetidae, Dipodidae, Mu- ridae and Sciuridae were captured. Five species of each fleas and lice were collected from the body of the trapped rodents. Three flea species, Ctenophthalmus pseudagyrtes, Nosopsyllus iranus and Xenopsylla buxtoni; and two louse species, Polyplax gerbilli and P. spinulosa, were recorded for the first time.The study generated an annotated checklist of 79 species of fleas and 8 species of lice harboured by different species of rodents distributed in Iran which would

2019 Journal of Vector Borne Disease

5. Head lice infestations: A clinical update

Head lice infestations: A clinical update Head lice ( Pediculus humanus capitis ) infestations are not a primary health hazard or a vector for disease, but they are a societal problem with substantial costs. Diagnosis of head lice infestation requires the detection of a living louse. Although pyrethrins and permethrin remain first-line treatments in Canada, isopropyl myristate/ST-cyclomethicone solution and dimeticone can be considered as second-line therapies when there is evidence (...) of treatment failure. Keywords: Dimeticone solution; Head lice; Infestations; Isopropyl myristate/cyclomethicone solution; Permethrin; Pyrethrin.

2016 Canadian Paediatric Society

6. Randomized, investigator-blinded, controlled clinical study with lice shampoo (Licener®) versus dimethicone (Jacutin® Pedicul Fluid) for the treatment of infestations with head lice. (PubMed)

Randomized, investigator-blinded, controlled clinical study with lice shampoo (Licener®) versus dimethicone (Jacutin® Pedicul Fluid) for the treatment of infestations with head lice. The present clinical trial was conducted to obtain additional data for the safety and efficacy of a head lice shampoo that is free of silicone compared with an anti-head lice product containing dimethicone. Both products act by a physical mode of action. This randomized, investigator-blinded, controlled clinical (...) study was conducted between July and November 2016 in households of two villages (Abou Rawash and Shandalat) in Egypt. Children older than 2 years with an active head lice infestation were treated with either a shampoo-based head lice treatment containing neem extract (Licener®) or dimethicone (Jacutin® Pedicul Fluid) on day 1 and additionally on day 9. Assessment for living lice by combing was conducted before and 1-2 h after treatment and on days 5 and 13. The main objective was to demonstrate

2017 Parasitology research

7. High Ancient Genetic Diversity of Human Lice, Pediculus humanus, from Israel Reveals New Insights into the Origin of Clade B Lice. (PubMed)

High Ancient Genetic Diversity of Human Lice, Pediculus humanus, from Israel Reveals New Insights into the Origin of Clade B Lice. The human head louse, Pediculus humanus capitis, is subdivided into several significantly divergent mitochondrial haplogroups, each with particular geographical distributions. Historically, they are among the oldest human parasites, representing an excellent marker for tracking older events in human evolutionary history. In this study, ancient DNA analysis using (...) real-time polymerase chain reaction (qPCR), combined with conventional PCR, was applied to the remains of twenty-four ancient head lice and their eggs from the Roman period which were recovered from Israel. The lice and eggs were found in three combs, one of which was recovered from archaeological excavations in the Hatzeva area of the Judean desert, and two of which found in Moa, in the Arava region, close to the Dead Sea. Results show that the head lice remains dating approximately to 2,000 years

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2016 PLoS ONE

8. Primates, Lice and Bacteria: Speciation and Genome Evolution in the Symbionts of Hominid Lice (PubMed)

Primates, Lice and Bacteria: Speciation and Genome Evolution in the Symbionts of Hominid Lice Insects with restricted diets rely on symbiotic bacteria to provide essential metabolites missing in their diet. The blood-sucking lice are obligate, host-specific parasites of mammals and are themselves host to symbiotic bacteria. In human lice, these bacterial symbionts supply the lice with B-vitamins. Here, we sequenced the genomes of symbiotic and heritable bacterial of human, chimpanzee, gorilla (...) , and monkey lice and used phylogenomics to investigate their evolutionary relationships. We find that these symbionts have a phylogenetic history reflecting the louse phylogeny, a finding contrary to previous reports of symbiont replacement. Examination of the highly reduced symbiont genomes (0.53-0.57 Mb) reveals much of the genomes are dedicated to vitamin synthesis. This is unchanged in the smallest symbiont genome and one that appears to have been reorganized. Specifically, symbionts from human lice

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2017 Molecular Biology and Evolution

9. Orientation of Head Lice on Human Hosts, and Consequences for Transmission of Pediculosis: The Head Lice Movement Studies (PubMed)

Orientation of Head Lice on Human Hosts, and Consequences for Transmission of Pediculosis: The Head Lice Movement Studies We performed head lice movement studies to elucidate factors influencing orientation and movement of head lice. Studies included observation of lice movements on hand and forearm at different positions of the upper limb; movements exposed to unshaved and shaved forearm; and movements with and without antennae. In 57 of 60 (95.0%) observations while holding the hand down (...) , lice moved proximal, and 3 (5%) distal. While holding the hand up, 37/60 (61.7%) moved proximal, and 23 (38.3%) distal (p < 0.0001). On the unshaved limb, 29/30 (96.7%) moved proximal, with clockwise movements in 26/30 (86.7%). After shaving, 9/30 (30%) walked proximal and 18 (60%) distal, with 12/30 (40%) clockwise movements. After antennectomy, while holding the hand up, 16/25 (64%) lice did not move, 1 (4%) walked proximal, and 8 (32%) distal. While handing the hand down, 17/25 (68%) did

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2017 Tropical Medicine and Infectious Disease

10. Sea lice, Lepeophtheirus salmonis (Krøyer 1837), infected Atlantic salmon (Salmo salar L.) are more susceptible to infectious salmon anemia virus. (PubMed)

Sea lice, Lepeophtheirus salmonis (Krøyer 1837), infected Atlantic salmon (Salmo salar L.) are more susceptible to infectious salmon anemia virus. The role of parasitic sea lice (Siphonostomatoida; Caligidae), especially Lepeophtheirus salmonis, in the epidemiology of Infectious Salmon Anemia Virus (ISAv) has long been suspected. The epidemiological studies conducted during the 1998 major Infectious Salmon Anaemia (ISA) outbreak in Scotland demonstrated a strong correlation between sea lice (...) presence and ISAv positive sites or subsequent clinical outbreaks of ISA. The question posed from this observation was "do sea lice infestations on Atlantic salmon make them more susceptible to viral infections?" This study investigated the role that sea lice infestations have on the severity of ISAv infections and disease mortality in experimental populations of farmed Atlantic salmon (Salmo salar). A series of experiments was carried out that investigated the potential of sea lice to modify

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2019 PLoS ONE

11. Correction: Efficacy of Peer Education for Adopting Preventive Behaviors against Head Lice Infestation in Female Elementary School Students: A Randomised Controlled Trial. (PubMed)

Correction: Efficacy of Peer Education for Adopting Preventive Behaviors against Head Lice Infestation in Female Elementary School Students: A Randomised Controlled Trial. [This corrects the article DOI: 10.1371/journal.pone.0169361.].

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2019 PLoS ONE

12. Correction: Sea lice, Lepeophtheirus salmonis (Krøyer 1837), infected Atlantic salmon (Salmo salar L.) are more susceptible to infectious salmon anemia virus. (PubMed)

Correction: Sea lice, Lepeophtheirus salmonis (Krøyer 1837), infected Atlantic salmon (Salmo salar L.) are more susceptible to infectious salmon anemia virus. [This corrects the article DOI: 10.1371/journal.pone.0209178.].

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2019 PLoS ONE

13. Head lice: Dimeticone is the pediculicide of choice

Head lice: Dimeticone is the pediculicide of choice Prescrire IN ENGLISH - Spotlight ''Head lice: Dimeticone is the pediculicide of choice '', 1 July 2014 {1} {1} {1} | | > > > Head lice: Dimeticone is the pediculicide of choice Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Head lice: Dimeticone is the pediculicide of choice FEATURED REVIEW (...) Pyrethroids are no longer the first-choice treatment for head lice: they are losing effectiveness and may be toxic in the long term. Dimeticone is a better choice, because it has few known adverse effects and proven efficacy. Full review (4 pages) available for download by subscribers. Abstract Infestation of the scalp by head lice , or pediculosis, is a common, unpleasant but harmless parasitosis. For patients with pediculosis , which topical treatment eradicates the parasites effectively while causing

2014 Prescrire

14. Wet combing for head lice

Wet combing for head lice RACGP - Wet combing for head lice Search Become a student member today for free and be part of the RACGP community A career in general practice Starting the GP journey Enrolments for the 2019.1 OSCE FRACGP exams closing 29 March 2019 Fellowship FRACGP exams Research Practice Experience Program is a self-directed education program designed to support non vocationally registered doctors on their pathway to RACGP Fellowship Fellowship International graduates FRACGP exams (...) Media Releases 2013 Media Releases 2012 Media Releases Search Wet combing: head lice Wet combing: head lice Introduction Half of the people infested with lice do not scratch; all people in contact with an affected person should be manually checked for lice. Intervention Manual (condition and comb or wet comb) removal using the Bug Buster® kit, Quit Nits Combing Solution® or other head lice comb. Indication Head lice ( Pediculosis capitis) infestation. Suitable for insecticide resistant infestations

2013 Handbook of Non-Drug interventions (HANDI)

15. Gene Expression Response to Sea Lice in Atlantic Salmon Skin: RNA Sequencing Comparison Between Resistant and Susceptible Animals (PubMed)

Gene Expression Response to Sea Lice in Atlantic Salmon Skin: RNA Sequencing Comparison Between Resistant and Susceptible Animals Sea lice are parasitic copepods that cause large economic losses to salmon aquaculture worldwide. Frequent chemotherapeutic treatments are typically required to control this parasite, and alternative measures such as breeding for improved host resistance are desirable. Insight into the host-parasite interaction and mechanisms of host resistance can lead (...) to improvements in selective breeding, and potentially novel treatment targets. In this study, RNA sequencing was used to study the skin transcriptome of Atlantic salmon (Salmo salar) parasitized with sea lice (Caligus rogercresseyi). The overall aims were to compare the transcriptomic profile of skin at louse attachment sites and "healthy" skin, and to assess differences in gene expression response between animals with varying levels of resistance to the parasite. Atlantic salmon pre-smolts were challenged

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2018 Frontiers in genetics

16. Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarettes

Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarettes Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarettes - GOV.UK GOV.UK uses cookies to make the site simpler. Search Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarettes Pharmacists (...) should tell people about the risk of fire when they discuss head lice eradication options. Published 8 March 2018 From: Therapeutic area: , Contents Advice to pharmacists some products for the eradication of head lice infestations are combustible/flammable when on the hair and can ignite and cause serious harm in the presence of an open flame or other source of ignition such as when lighting cigarettes advise parents, caregivers and the person with head lice, if appropriate, that they should

2018 MHRA Drug Safety Update

17. Body lice of homeless people reveal the presence of several emerging bacterial pathogens in northern Algeria (PubMed)

Body lice of homeless people reveal the presence of several emerging bacterial pathogens in northern Algeria Human lice, Pediculus humanus, are obligate blood-sucking parasites. Body lice, Pediculus h. humanus, occur in two divergent mitochondrial clades (A and D) each exhibiting a particular geographic distribution. Currently, the body louse is recognized as the only vector for louse-borne diseases. In this study, we aimed to study the genetic diversity of body lice collected from homeless (...) populations in three localities of northern Algeria, and to investigate louse-borne pathogens in these lice.In this study, 524 body lice specimens were collected from 44 homeless people in three localities: Algiers, Tizi Ouzou and Boumerdès located in northern Algeria. Duplex clade specific real-time PCRs (qPCR) and Cytochrome b (cytb) mitochondrial DNA (mtDNA) analysis were performed in order to identify the mitochondrial clade. Screening of louse-borne pathogens bacteria was based on targeting specific

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2018 PLoS neglected tropical diseases

18. Characterisation of proteins in excretory/secretory products collected from salmon lice, Lepeophtheirus salmonis (PubMed)

Characterisation of proteins in excretory/secretory products collected from salmon lice, Lepeophtheirus salmonis The salmon louse, Lepeophtheirus salmonis, is an ectoparasitic copepod which feeds on the mucus, skin and blood of salmonid fish species. The parasite can persist on the surface of the fish without any effective control being exerted by the host immune system. Other ectoparasitic invertebrates produce compounds in their saliva, excretions and/or secretions which modulate the host (...) lice and pre-adult sea lice. Fifty-three proteins, including 13 serine-type endopeptidases, 1 peroxidase and 5 vitellogenin-like proteins were common to both adult and pre-adult E/S products. One hundred and seven proteins were identified in the adult E/S but not in the pre-adult E/S and these included serine and cysteine-type endopeptidases, vitellogenins, sphingomyelinase and calreticulin. A total of 27 proteins were identified in pre-adult E/S products but not in adult E/S.The assigned functions

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2018 Parasites & vectors

19. Detection of bacterial pathogens in clade E head lice collected from Niger’s refugees in Algeria (PubMed)

Detection of bacterial pathogens in clade E head lice collected from Niger’s refugees in Algeria Head lice, Pediculus humanus capitis, are obligate blood-sucking parasites. Phylogenetically, they occur in five divergent mitochondrial clades (A, D, B, C and E), each having a particular geographical distribution. Recent studies have revealed that head lice, as is the case of body lice, can act as a vector for louse-borne diseases. Here, we aimed to study the genetic diversity of head lice (...) collected from Niger's refugees (migrant population) arriving in Algeria, northern Africa, and to look for louse-borne pathogens. Comparative head lice samples collected from indigenous population of schoolchildren (non-immigrant) were also analyzed to frame the study.In this study, 37 head lice samples were collected from 31 Nigerien refugees, as well as 45 head lice from 27 schoolchildren. The collection was established in three localities of eastern Algiers, north Algeria. Quantitative real-time PCR

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2018 Parasites & vectors

20. A Clinical Trial to Evaluate Efficacy and Safety of a Water-soluble Head Lice Product.

A Clinical Trial to Evaluate Efficacy and Safety of a Water-soluble Head Lice Product. A Clinical Trial to Evaluate Efficacy and Safety of a Water-soluble Head Lice Product. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. A Clinical Trial to Evaluate Efficacy and Safety of a Water-soluble Head Lice Product. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03617926 Recruitment Status : Completed First Posted : August 7, 2018 Last Update Posted : August 7, 2018 Sponsor: Oystershell NV Information

2018 Clinical Trials

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