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Lemierre Syndrome

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101. Microbiology of Para- og Retropharyngeal Abscess

findings in concomitant peritonsillar and parapharyngeal abscesses. Characterize patients with para- and retropharyngeal abscess. Compare the concentration of amylase in para- and retropharyngeal abscesses and neck abscesses without relation to the pharynx or salivary glands. Perform gene-sequencing of F. Necrophorum strains, and compare these with strains recovered from patients with acute tonsillitis, peritonsillar abscess, and Lemierre´s syndrome. Condition or disease Intervention/treatment (...) abscess bacteriology Fusobacterium necrophorum Additional relevant MeSH terms: Layout table for MeSH terms Abscess Retropharyngeal Abscess Suppuration Infection Inflammation Pathologic Processes Pharyngitis Pharyngeal Diseases Stomatognathic Diseases Respiratory Tract Infections Respiratory Tract Diseases Otorhinolaryngologic Diseases

2015 Clinical Trials

102. Fusobacterial head and neck infections in children. (Abstract)

Fusobacterial head and neck infections in children. Fusobacterium species are increasingly recognized as a cause of head and neck infections in children. These infections include acute and chronic otitis, sinusitis, mastoiditis, and tonsillitis; peritonsillar and retropharyngeal abscesses; Lemierre syndrome; post-anginal cervical lymphadenitis; and periodontitis. They can also be involved in brain abscess and bacteremia associated with head and neck infections. This review describes

2015 International Journal of Pediatric Otorhinolaryngology

103. A 28-year-old pregnant woman with a very rare cause of jugular vein thrombosis. (Abstract)

A 28-year-old pregnant woman with a very rare cause of jugular vein thrombosis. During pregnancy, venous thrombosis of the distal extremities is not uncommon. However, thrombosis in the upper part of the body, such as jugular vein thrombosis, is rare. If underlying causes such as ovarian hyperstimulation syndrome (OHSS) or septic thrombophlebitis (Lemierre's syndrome) are excluded, a serous borderline ovary tumour (BOT) must be considered and MR imaging of the abdomen could be performed to find

2014 Netherlands Journal of Medicine

104. Fusobacterium necrophorum tonsillitis: an important cause of tonsillitis in adolescents and young adults. Full Text available with Trip Pro

with clinical tonsillitis (27%) compared to subjects with no clinical tonsillitis (6%). These results clearly demonstrate the role of F. necrophorum in tonsillitis. By diagnosing and treating F. necrophorum tonsillitis with, for example, penicillin, metronidazole, or both, we might prevent some cases of Lemierre syndrome.Copyright © 2014 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

2014 Clinical Microbiology and Infection

105. The challenge of “evidence based” sore throat guidelines Full Text available with Trip Pro

against treating these sore throat patients and perhaps preventing suppurative complications. What makes me so passionate? Why is my bias for antibiotics for adolescent/young adults with Centor scores of 3 or 4? Imagine an infectious disease that responds to standard antibiotics. Like endocarditis it causes septic emboli. This infection often causes diagnostic errors, because few physicians see a patient while in training, or have the disease even discussed. The Lemierre Syndrome is that devastating (...) contagious. It occasionally causes streptococcal shock syndrome with the rare death. Treatment probably decreases duration of symptoms in adolescents and young adults, but not significantly in childhood. Some Europeans now consider GAS sore throat a self-limited disease that we need not treat. They discount the ARF risk and thus view the potential negative side effects from antibiotics a greater problem. We know that in adolescents and young adults, group C/G streptococcus and Fusobacterium necrophorum

2017 db's Medical Rants blog

106. My developing thoughts on adult pharyngitis

in a conversation I had yesterday at the University of Nebraska where I am this week as a visiting professor. A clinician educator asked me about “red flags” in sore throat patients. While I have written this previously, repetition helps all learners remember. Adult sore throats generally last around 3-5 days. The patient no longer has a routine sore throat when: It continues feeling worse – most Lemierre syndrome patients complain that they precedent sore throat was the worst they ever had The patient develops (...) rigors – Lemierre included this in his classic article, and we have found this in our clinical experience. Lemierre syndrome patients have bacteremia and the body responds with rigors (and somewhat less often drenching sweats) Unilateral neck swelling – requires imaging looking for either peritonsillar abscess or internal jugular suppurative thrombophlebitis. Most sore throats are totally benign – either with or without antibiotic treatment. But, our job is to be aware of the unusual presentations

2017 db's Medical Rants blog

107. FeverPAIN vs the Centor Score

a careful evaluation for either suppurative complications (peritonsillar abscess or Lemierre syndrome) or one should consider significant viral infections in adults – infectious mononucleosis and acute HIV. The other problem that I have with the FeverPAIN analysis is the lack of distinction between preadolescents and adolescent/young adults. We have written about this problem, both in MEDRANTS and in this article – The streptococcal carrier rates for pre-adolescents are MUCH higher than for adolescents

2017 db's Medical Rants blog

108. Arcanobacterium Haemolyticum (Treatment)

report. Ophthal Plast Reconstr Surg . 2015 Mar-Apr. 31 (2):e31-3. . Balakrishnan D. Arcanobacterium Hemolyticum Chorioamnionitis Leading to Preterm Labour – A Case Report. Basic Sci Med . 2017. 6(1):1-4. Smith HM, Arul I. Wound Infection and Sepsis Caused by Arcanobacterium haemolyticum. Clin Microbiol News . 2016. 38(6):49-50. Younus F, Chua A, Tortora G, Jimenez VE. Lemierre's disease caused by co-infection of Arcanobacterium haemolyticum and Fusobacterium necrophorum: a case report. J Infect (...) you like to print? Sections Arcanobacterium Haemolyticum Find Us On About Membership WebMD Network Editions All material on this website is protected by copyright, Copyright © 1994-2019 by WebMD LLC. This website also contains material copyrighted by 3rd parties. Close encoded search term (Arcanobacterium Haemolyticum) and Arcanobacterium Haemolyticum What to Read Next on Medscape Related Conditions and Diseases Medscape Consult News & Perspective Tools Slideshow Most Popular Articles According

2014 eMedicine.com

109. Infectious Mononucleosis (Treatment)

-Barr virus (EBV) infectious mononucleosis. Next: Surgical Care Surgery is necessary for spontaneous splenic rupture, which occurs in rare patients with EBV infectious mononucleosis and may be the initial manifestation of the condition. Previous Next: Consultations Consult an infectious disease specialist in all but the most straightforward cases of EBV infectious mononucleosis. Consulting a hematologist may be necessary if unusual hematologic manifestations of EBV infectious mononucleosis (...) with human neoplasia. Pathol Annu . 1992. 27 Pt 1:55-74. . Gill MV, Cunha BA. Streptococcal colonization versus infection. Infect Dis Pract . 1994. 18:16. Glaser SL, Lin RJ, Stewart SL, Ambinder RF, Jarrett RF, Brousset P, et al. Epstein-Barr virus-associated Hodgkin's disease: epidemiologic characteristics in international data. Int J Cancer . 1997 Feb 7. 70(4):375-82. . Godshall SE, Kirchner JT. Infectious mononucleosis. Complexities of a common syndrome. Postgrad Med . 2000 Jun. 107(7):175-9, 183-4

2014 eMedicine.com

110. Pharyngitis, Bacterial (Overview)

information on pharyngitis in children, see the Medscape Reference article . Previous Next: Prognosis GABHS pharyngitis is usually a self-limited illness. Throat symptoms resolve within 3-4 days in untreated patients. Administration of penicillin shortly after disease onset may shorten symptoms by 1-2 days. [ ] Previous Next: Patient Education Symptomatic relief may be provided by warm saline gargles, throat lozenges, and ibuprofen. Acetaminophen or ibuprofen can be used for fever relief. Patients (...) . Clin Microbiol Infect . 2007 Jul. 13(7):695-701. . Lundin MS, Bastakoti S, Havlichek D, Laird-Fick H. Lemierre's syndrome and 2016 American College of Physician guidelines for pharyngitis: no to empiric coverage for bacterial pharyngitis. While no role for routine Fusobacterium PCR, keep suspicion for this pathogen. BMJ Case Rep . 2018 Jul 19. 2018: . Catanzaro FJ, Stetson CA, Morris AJ, et al. The role of the streptococcus in the pathogenesis of rheumatic fever. Am J Med . 1954 Dec. 17(6):749-56

2014 eMedicine.com

111. Pharyngitis, Bacterial (Treatment)

bacterial infection, antibiotics should not be prescribed. In contrast, a steroid may be prescribed to relieve symptoms in patients with infectious mononucleosis. Previous Next: Consultations An otolaryngologist should be consulted for local suppurative complications such as peritonsillar abscess and . may be considered in recurrent GABHS infection. [ , ] An infectious diseases expert may be consulted for patients with immunocompromising conditions or when an agent other than GABHS (eg, HIV (...) ) is suspected or confirmed. Previous Next: Diet Allow a regular diet as tolerated in patients with bacterial pharyngitis. Warm liquids may provide symptomatic relief. Previous Next: Activity Encourage rest during the acute illness. Previous Next: Prevention Patients with bacterial pharyngitis should be kept out of daycare, school, or work until 24 hours after the initiation of antibiotics. Vaccination Despite the massive disease burden caused by S pyogenes (GAS) infection, no licensed vaccine is available

2014 eMedicine.com

112. Lung Abscess (Overview)

, not 1, but 4 microbes, thought to be Fusobacterium nucleatum, Peptostreptococcus species, a fastidious gram-negative anaerobe, and, possibly, Prevotella melaninogenicus . Lung abscess was a devastating disease in the preantibiotic era, when one third of the patients died, another one third recovered, and the remainder developed debilitating illnesses such as recurrent abscesses, chronic empyema, bronchiectasis, or other consequences of chronic pyogenic infections. In the early postantibiotic period (...) necrosis 7-14 days later, resulting in formation of lung abscess. Other mechanisms for lung abscess formation include bacteremia or tricuspid valve endocarditis causing septic emboli (usually multiple) to the lung. Lemierre syndrome, an acute oropharyngeal infection followed by of the internal jugular vein, is a rare cause of lung abscesses. The oral anaerobe F necrophorum is the most common pathogen. Microbiology Because of the difficulty obtaining material uncontaminated by nonpathogenic bacteria

2014 eMedicine.com

113. Infectious Mononucleosis (Overview)

pneumoniae preceding Lemierre's syndrome due to Fusobacterium nucleatum complicated by acute Epstein-Barr virus (EBV) infectious mononucleosis in an immunocompetent host. Heart Lung . 2013 Jan. 42(1):74-6. . Klemola E, Von Essen R, Henle G, et al. Infectious-mononucleosis-like disease with negative heterophil agglutination test. Clinical features in relation to Epstein-Barr virus and cytomegalovirus antibodies. J Infect Dis . 1970 Jun. 121(6):608-14. . Koj IG, Cunha BA. EBV infectious mononucleosis (...) of mononucleosis-like illnesses. Am J Med . 2007 Oct. 120(10):911.e1-8. . Schlossberg D. Infectious Mononucleosis . 2nd Ed. New York: Springer-Verlag; 1988. Jacobs BC, Rothbarth PH, van der Meche FG, et al. The spectrum of antecedent infections in Guillain-Barre syndrome: a case-control study. Neurology . 1998 Oct. 51(4):1110-5. . Jappe U. Amoxicillin-induced exanthema in patients with infectious mononucleosis: allergy or transient immunostimulation?. Allergy . 2007 Dec. 62(12):1474-5. . Jenson HB. Acute

2014 eMedicine.com

114. Thrombophlebitis (Treatment)

a sore throat to the intensive care unit: the Lemierre syndrome. Wien Klin Wochenschr . 2006 May. 118(7-8):243-6. . Brinsuk M, Tank J, Luft FC, Busjahn A, Jordan J. Heritability of venous function in humans. Arterioscler Thromb Vasc Biol . 2004 Jan. 24(1):207-11. . Tröbinger C, Wiedermann CJ. Bodybuilding-induced Mondor's disease of the chest wall. Phys Ther Sport . 2017 Jan. 23:133-135. . Amano M, Shimizu T. Mondor's Disease: A Review of the Literature. Intern Med . 2018 May 18. . Belcaro G (...) venous thromboembolism. Thromb Haemost . 1997 Oct. 78(4):1183-8. . Beller FK. Thromboembolic disease in pregnancy. Anderson A, ed. Thromboembolic Disorders . New York, NY: Harper & Row; 1968. Homans J. Thrombosis of the deep leg veins due to prolonged sitting. N Engl J Med . 1954 Jan 28. 250(4):148-9. . Lord RS, McGrath M. Travelers venous thrombosis. 1993. Cushman M. Epidemiology and risk factors for venous thrombosis. Semin Hematol . 2007 Apr. 44(2):62-9. . Lord RS. Air travel-related deep venous

2014 eMedicine.com

115. Arcanobacterium Haemolyticum (Diagnosis)

presenting with a deep ulcer. [ ] Diabetic patients are more vulnerable to infection by A haemolyticum , and wound and blood cultures are appropriate if the patient appears septic. Multiple wound cultures may be required before A haemolyticum is identified. A haemolyticum is sometimes a copathogen with other bacteria, including with Fusobacterium necrophorum in one case of Lemierre disease. [ ] Although A haemolyticum has been implicated in a wide spectrum of diseases, it has been most commonly (...) . . Balakrishnan D. Arcanobacterium Hemolyticum Chorioamnionitis Leading to Preterm Labour – A Case Report. Basic Sci Med . 2017. 6(1):1-4. Smith HM, Arul I. Wound Infection and Sepsis Caused by Arcanobacterium haemolyticum. Clin Microbiol News . 2016. 38(6):49-50. Younus F, Chua A, Tortora G, Jimenez VE. Lemierre's disease caused by co-infection of Arcanobacterium haemolyticum and Fusobacterium necrophorum: a case report. J Infect . 2002 Aug. 45(2):114-7. . Nyman M, Alugupalli KR, Strömberg S, Forsgren

2014 eMedicine.com

116. Pharyngitis, Bacterial (Follow-up)

bacterial infection, antibiotics should not be prescribed. In contrast, a steroid may be prescribed to relieve symptoms in patients with infectious mononucleosis. Previous Next: Consultations An otolaryngologist should be consulted for local suppurative complications such as peritonsillar abscess and . may be considered in recurrent GABHS infection. [ , ] An infectious diseases expert may be consulted for patients with immunocompromising conditions or when an agent other than GABHS (eg, HIV (...) ) is suspected or confirmed. Previous Next: Diet Allow a regular diet as tolerated in patients with bacterial pharyngitis. Warm liquids may provide symptomatic relief. Previous Next: Activity Encourage rest during the acute illness. Previous Next: Prevention Patients with bacterial pharyngitis should be kept out of daycare, school, or work until 24 hours after the initiation of antibiotics. Vaccination Despite the massive disease burden caused by S pyogenes (GAS) infection, no licensed vaccine is available

2014 eMedicine.com

117. Pharyngitis, Bacterial (Diagnosis)

information on pharyngitis in children, see the Medscape Reference article . Previous Next: Prognosis GABHS pharyngitis is usually a self-limited illness. Throat symptoms resolve within 3-4 days in untreated patients. Administration of penicillin shortly after disease onset may shorten symptoms by 1-2 days. [ ] Previous Next: Patient Education Symptomatic relief may be provided by warm saline gargles, throat lozenges, and ibuprofen. Acetaminophen or ibuprofen can be used for fever relief. Patients (...) . Clin Microbiol Infect . 2007 Jul. 13(7):695-701. . Lundin MS, Bastakoti S, Havlichek D, Laird-Fick H. Lemierre's syndrome and 2016 American College of Physician guidelines for pharyngitis: no to empiric coverage for bacterial pharyngitis. While no role for routine Fusobacterium PCR, keep suspicion for this pathogen. BMJ Case Rep . 2018 Jul 19. 2018: . Catanzaro FJ, Stetson CA, Morris AJ, et al. The role of the streptococcus in the pathogenesis of rheumatic fever. Am J Med . 1954 Dec. 17(6):749-56

2014 eMedicine.com

118. Mastoiditis (Overview)

. Masked mastoiditis. Laryngoscope . 1983 Aug. 93(8):1034-7. . Oestreicher-Kedem Y, Raveh E, Kornreich L, et al. Complications of mastoiditis in children at the onset of a new millennium. Ann Otol Rhinol Laryngol . 2005 Feb. 114(2):147-52. . Fischer JB, Prout A, Blackwood RA, Warrier K. Lemierre Syndrome Presenting as Acute Mastoiditis in a 2-Year-Old Girl with Congenital Dwarfism. Infect Dis Rep . 2015 Apr 15. 7 (2):5922. . Enoksson F, Groth A, Hultcrantz M, Stalfors J, Stenfeldt K, Hermansson (...) material on this website is protected by copyright, Copyright © 1994-2019 by WebMD LLC. This website also contains material copyrighted by 3rd parties. Close encoded search term (Pediatric Mastoiditis) and Pediatric Mastoiditis What to Read Next on Medscape Related Conditions and Diseases Medscape Consult News & Perspective Tools Slideshow Most Popular Articles According to Pediatricians Recommended 2002 994656-overview Diseases & Conditions Diseases & Conditions 2002 858990-overview Procedures

2014 eMedicine Pediatrics

119. Infections of the Lung, Pleura and Mediastinum: Surgical Perspective (Overview)

contains fat and lymphoid tissue. The middle mediastinum comprises the heart, pericardium, aorta, carina, mainstem bronchi, and lymph nodes. The posterior mediastinum includes the esophagus, descending aorta, vagus nerve, and thoracic duct. Chest radiographs and computed tomography images of patients with mediastinitis follow. CT scan of the thorax of a sixteen-year-old with Lemierre's syndrome and anterior mediastinitis revealing pneumomediastinum posterior to and to the left of the trachea, free (...) fluid surrounding the trachea, and left pleural effusion. CT scan of the thorax with intravenous contrast of a sixteen-year-old with Lemierre's syndrome and anterior mediastinitis revealing development of ring-enhancing fluid collections in the anterior mediastinum just posterior to the sternum. CT scan of the thorax with intravenous contrast of a sixteen-year-old with Lemierre's syndrome and anterior mediastinitis revealing a right pleural ring-enhancing abscess which persisted following drainage

2014 eMedicine Pediatrics

120. Drainage, Peritonsillar Abscess

looked at the bacteriology of PTA aspirates. A mixture of aerobic and anaerobic bacteria is commonly isolated. [ , ] The most common aerobic bacteria are Streptococcus group A (GAS), beta-hemolytic streptococci group C and G, and Staphylococcus aureus . The most common anaerobic bacteria isolated from PTA aspirates is Fusobacterium necrophorum (FN). FN is a gram-negative, obligate anaerobic, pleomorphic rod. It is also the pathogen most commonly associated with Lemierre syndrome. [ , ] In one study (...) Procedures) and Peritonsillar Abscess Drainage Procedures What to Read Next on Medscape Related Conditions and Diseases Medscape Consult News & Perspective Tools Slideshow Most Popular Articles According to General Surgeons Recommended 2002 858001-overview Procedures Procedures 2002 849233-overview Procedures Procedures 2001 /viewarticle/889211 Journal Article Journal Article 2001 /viewarticle/908860 News News Need a Curbside Consult? Share cases and questions with Physicians on Medscape consult.

2014 eMedicine.com

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