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Lemierre Syndrome

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61. Some neck swellings are serious; a case of Lemierre’s Syndrome (PubMed)

Some neck swellings are serious; a case of Lemierre’s Syndrome Lemierre's syndrome also termed post-anginal septicemia, is a disease characterized by internal jugular septic thrombophlebitis leading to Fusobacterium septicemia with multiple metastatic foci following an oropharyngeal infection. Diagnosis and management is challenging and can result in fatal consequences due to potential multisystem involvement and multiple complications. We describe here a case of Lemierre's syndrome

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2017 Journal of community hospital internal medicine perspectives

62. Lemierre’s syndrome: current perspectives on diagnosis and management (PubMed)

Lemierre’s syndrome: current perspectives on diagnosis and management This is a systematic review of cases with Lemierre's syndrome (LS) in the past 5 years. LS is characterized by sepsis often evolving after a sore throat or tonsillitis and then complicated by various septic emboli and thrombosis of the internal jugular vein. Symptoms include sepsis, pain, and/or swelling in the throat or neck, as well as respiratory symptoms. Laboratory findings show elevated infectious parameters (...) and radiological findings show thrombosis of the internal jugular vein and emboli in the lungs or other organs. The syndrome is often associated with an infection with Fusobacterium necrophorum. We found a total of 137 cases of LS, of which 47 were infected with F. necrophorum and others with Staphylococcus and Streptococcus. Complications of this rare but severe disease included osteomyelitis, meningitis, and acute respiratory distress syndrome. Mortality was extremely high in the pre-antibiotic era but has

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2016 Infection and drug resistance

63. The Forgotten One: Lemierre’s Syndrome Due to Gram-Negative Rods Prevotella Bacteremia (PubMed)

The Forgotten One: Lemierre’s Syndrome Due to Gram-Negative Rods Prevotella Bacteremia Lemierre's syndrome (LS) is a rare syndrome caused by an acute oropharyngeal infection with metastatic spreading. It was described in 1939 as jugular vein septic thrombophlebitis associated with retropharyngeal infection. Different organisms can cause LS, such as Fusobacterium species, Peptostreptococcus, group B and C, Streptococcus, Staphylococcus, and Enterococcus species, but the most commonly isolated (...) antibiotics. Subsequent imaging of the chest showed pleural effusion with septic emboli. He underwent thoracentesis and chest tube placement. Final blood cultures were remarkable for gram-negative rods - Prevotella anaerobes - which supported the diagnosis of LS. His condition improved, including the dyspnea, and he was discharged on the proper antibiotics coverage with outpatient follow-up.LS is a rare condition associated with metastatic infection spreading. This syndrome can be associated with further

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2016 The American journal of case reports

64. Lemierre syndrome: unusual cause and presentation. (PubMed)

Lemierre syndrome: unusual cause and presentation. Lemierre syndrome is a potentially fatal condition after an oropharyngeal infection. It is characterized by thrombophlebitis of head and neck veins with systemic dissemination of septic emboli. The most frequently isolated pathogen is Fusobacterium necrophorum. We report an unusual case of Lemierre syndrome in a 4-year-old child caused by Staphylococcus aureus, with multivisceral emboli to the brain, orbits, lungs, and heart valves. We also (...) discuss its atypical clinical presentation, the crucial role of imaging in the early diagnosis, and the different treatment modalities of this life-threatening syndrome.

2010 Pediatric Emergency Care

65. Lemierre's Syndrome Mimicking Leptospirosis (PubMed)

Lemierre's Syndrome Mimicking Leptospirosis Lemierre's syndrome is a suppurative thrombophlebitis involving the internal jugular vein, most commonly associated with Fusobacterium necrophorum, usually a complication of oropharyngeal infections. This syndrome is rare and is often overlooked. We present a case of sepsis mimicking initially severe leptospirosis (Weil's disease) due to acute febrile illness with multiorgan failure and hyperbilirubinemia. Finally, blood cultures revealed

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2010 Hawaii Medical Journal

66. Liver abscessation and multiple septic pulmonary emboli associated with Lemierre’s syndrome: a case report (PubMed)

Liver abscessation and multiple septic pulmonary emboli associated with Lemierre’s syndrome: a case report In Lemierre's syndrome, patients first exhibit pharyngitis and peritonsillar abscessation, followed by the development of anaerobic bacterial (usually Fusobacterium necrophorum) septicemia and metastatic infections throughout the body. However, these infections rarely affect the liver. We describe a case of Lemierre's syndrome, in which the first disease manifestation was liver abscess (...) suspected. The patient was hospitalized and antibiotic treatment was initiated. On hospital day 6, blood culture results confirmed Fusobacterium necrophorum septicemia. The patient was diagnosed with Lemierre's syndrome, as pharyngitis developed into bacteremia associated with hepatic and pulmonary lesions. The patient's condition improved with antibiotics and he was discharged following three weeks of treatment in the hospital.With the widespread use of antibiotics, Lemierre's syndrome is rarely

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2015 BMC research notes

67. Clival Syndrome Secondary to Anaerobic Mastoiditis in a 2-Year Old Child. (PubMed)

Clival Syndrome Secondary to Anaerobic Mastoiditis in a 2-Year Old Child. Complications of acute mastoiditis can occur in about 10-20% of cases. Clival syndrome is a rare complication of mastoiditis, involving the 6th and 12th cranial nerves. We describe a case of a child with mastoiditis and presumed Lemierre syndrome complicated by clival syndrome.

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2015 Pediatric Infectious Dsease Journal

68. Lemierre’s Syndrome (PubMed)

Lemierre’s Syndrome 24672595 2015 10 30 2018 11 13 1936-900X 15 2 2014 Mar The western journal of emergency medicine West J Emerg Med Lemierre's Syndrome. 125-6 10.5811/westjem.2013.12.20418 Shook Jayten J Lakeland Regional Medical Center, Department of Emergency Medicine, St Joseph, Michigan. Trigger Christopher C Lakeland Regional Medical Center, Department of Emergency Medicine, St Joseph, Michigan. eng Case Reports Journal Article United States West J Emerg Med 101476450 1936-900X IM (...) Adult Emergency Service, Hospital Female Humans Lemierre Syndrome complications diagnosis diagnostic imaging Neck Pain diagnostic imaging etiology Tomography, X-Ray Computed Original DateCompleted: 20140327 2013 11 19 2013 12 09 2014 3 28 6 0 2014 3 29 6 0 2014 3 29 6 1 ppublish 24672595 10.5811/westjem.2013.12.20418 wjem-15-125 PMC3966442 Laryngoscope. 2009 Aug;119(8):1552-9 19554637 J Thromb Thrombolysis. 2014 Apr;37(3):246-8 23686643 Acta Radiol. 2013 Jul;54(6):622-7 23528567

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2014 Western Journal of Emergency Medicine

69. Lemierre’s Syndrome presenting with neurological and pulmonary symptoms: Case report and review of the literature (PubMed)

Lemierre’s Syndrome presenting with neurological and pulmonary symptoms: Case report and review of the literature Lemierre's Syndrome (LS) is a potentially life-threatening condition, characterized by clinical or radiologic evidence of internal jugular vein thrombosis following an oropharyngeal infection, most commonly by Fusobacterium necrophorum. A high index of suspicion and early recognition is important for successful management and to prevent systemic complications like multiorgan

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2013 Annals of Indian Academy of Neurology

70. Just a simple case of tonsillitis? Lemierre’s Syndrome and thrombosis of the external jugular vein. (PubMed)

Just a simple case of tonsillitis? Lemierre’s Syndrome and thrombosis of the external jugular vein. Oropharyngeal infections are routinely encountered within general practice and accident and emergency departments. Most settle with simple analgesia and antibiotics; occasionally such patients may develop Lemierre's syndrome (LS) a rare and potentially fatal sequela that can be easily overlooked. We aim to highlight the main symptoms, pathology, investigations and management. © JSCR.

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2011 Journal of surgical case reports

71. Horner syndrome due to jugular vein thrombosis (Lemierre syndrome) (PubMed)

Horner syndrome due to jugular vein thrombosis (Lemierre syndrome) 21687297 2011 11 10 2018 11 13 1757-790X 2009 2009 BMJ case reports BMJ Case Rep Horner syndrome due to jugular vein thrombosis (Lemierre syndrome). bcr2007124479 10.1136/bcr.2007.124479 Habek M M Referral Center for Demyelinating Diseases of the Central Nervous System, University Department of Neurology, Zagreb School of Medicine and University Hospital Center, Zagreb, Croatia. Petravić D D Ozretić D D Brinar V V VV eng Journal (...) Article 2009 02 16 England BMJ Case Rep 101526291 1757-790X Horner syndrome Lemierre syndrome jugular vein thrombosis 2011 6 21 6 0 2009 1 1 0 0 2009 1 1 0 1 ppublish 21687297 10.1136/bcr.2007.124479 bcr.2007.124479 PMC3105937 Medicine (Baltimore). 2002 Nov;81(6):458-65 12441902

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2009 BMJ case reports

72. Sore throat (acute): antimicrobial prescribing

, parapharyngeal abscess or retropharyngeal abscess or Lemierre syndrome). See the evidence and committee discussion on choice of antibiotic. 1.2 Self-care All people with acute sore throat All people with acute sore throat 1.2.1 Consider paracetamol for pain or fever, or if preferred and suitable, ibuprofen. 1.2.2 Advise about the adequate intake of fluids. 1.2.3 Explain that some adults may wish to try medicated lozenges containing either a local anaesthetic, a non-steroidal anti-inflammatory drug (NSAID

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

73. A case of Lemierre syndrome (PubMed)

A case of Lemierre syndrome 19139613 2009 04 07 2018 11 13 0256-4947 29 1 2009 Jan-Feb Annals of Saudi medicine Ann Saudi Med A case of Lemierre syndrome. 58-60 Alherabi Ameen A Department of Otolaryngology/Head & Neck Surgery, Umm Al-Qura University, Al-Noor Specialist Hospital, Makkah, Saudi Arabia. herabi@hotmail.com eng Case Reports Journal Article Saudi Arabia Ann Saudi Med 8507355 0256-4947 IM Adult Empyema, Pleural etiology microbiology Fusobacterium Infections diagnosis microbiology (...) physiopathology Fusobacterium necrophorum isolation & purification Humans Jugular Veins microbiology pathology Male Syndrome Tomography, X-Ray Computed 2009 1 14 9 0 2009 1 14 9 0 2009 4 8 9 0 ppublish 19139613 08-001 PMC2813609 N Engl J Med. 2004 Apr 15;350(16):e14 15084710 Arch Pediatr. 2003 Dec;10(12):1071-4 14643536 Ann Vasc Surg. 2004 Mar;18(2):243-5 15253264 Acta Otorhinolaryngol Ital. 1998 Oct;18(5):332-7 10361747 J Chin Med Assoc. 2004 Aug;67(8):419-21 15553803 Acta Anaesthesiol Scand. 2005 Apr;49(4

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2009 Annals of Saudi Medicine

74. Lemierre's syndrome: A systematic review. (PubMed)

Lemierre's syndrome: A systematic review. Lemierre's syndrome is characterized by a history of recent oropharyngeal infection, clinical or radiological evidence of internal jugular vein thrombosis, and isolation of anaerobic pathogens, mainly Fusobacterium necrophorum. It was once called the forgotten disease because of its rarity, but it may not be that uncommon after all. This review aims to provide physicians with an update on the etiology, management, and prognosis of Lemierre's (...) syndrome.Systematic review using the terms: Lemierre's syndrome, postanginal septicemia, fusobacterium, internal jugular vein thrombosis.English literature; reviews, case reports, and case series.variants or atypical Lemierre's syndrome cases, negative fusobacteria cultures, and papers without radiological evidence of thrombophlebitis.Eighty-four studies fulfilled our inclusion criteria. The male to female ratio was 1:1, 2, and the ages ranged from 2 months to 78 years (median, 22 years). Main sources

2009 Laryngoscope

75. In reference to Lemierre's Syndrome: A Systematic Review. (PubMed)

In reference to Lemierre's Syndrome: A Systematic Review. 19890952 2010 01 11 2009 12 24 1531-4995 120 1 2010 Jan The Laryngoscope Laryngoscope In reference to Lemierre's Syndrome: A Systematic Review. 215; author reply 216 10.1002/lary.20754 Syed Mohammed Iqbal MI Baring David D Murray Craig C eng Comment Letter United States Laryngoscope 8607378 0023-852X IM Laryngoscope. 2009 Aug;119(8):1552-9 19554637 Fusobacterium Infections Fusobacterium necrophorum Humans Review Literature as Topic

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2009 Laryngoscope

76. Necrotizing fasciitis of the neck associated with Lemierre syndrome (PubMed)

Necrotizing fasciitis of the neck associated with Lemierre syndrome Necrotizing fasciitis of the head and neck is a rare, life-threatening, soft tissue infection rapidly involving superficial fat and fascia with necrosis of the overlying skin. If septic thrombophlebitis of the internal jugular vein complicates a parapharyngeal abscess, the clinical condition is referred to as Lemierre syndrome, also known as post-anginal sepsis. A lethal case of necrotizing fasciitis of the neck is herewith

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2009 Acta Otorhinolaryngologica Italica

77. Lemierre syndrome complicating otitis externa: case report and literature review. (PubMed)

Lemierre syndrome complicating otitis externa: case report and literature review. Septic thrombophlebitis of the internal jugular vein, known as Lemierre syndrome, is a rare disorder usually caused by Fusobacterium necrophorum, a Gram-negative anaerobic organism that normally inhabits the oropharynx. Lemierre syndrome usually follows primary oropharyngeal infections and affects previously healthy adolescents and young adults in a characteristic manner, often with fatal results if left untreated (...) . There have been a significantly increasing number of reported cases of Lemierre syndrome, possibly reflecting the trend to withhold antibiotics for initially uncomplicated oropharyngeal infections.We hope to alert the reader to a potentially fatal disease process that has recently been increasingly identified, by reporting a unique manifestation of Lemierre syndrome, and by reviewing the current literature.A 19-year-old woman presented to our Emergency Department with a chief complaint of fever, ear pain

2009 Journal of Emergency Medicine

78. Management of Stroke in Neonates and Children

and to indicate gaps in current knowledge. This scientific statement is based on expert consensus considerations for clinical practice. Results— Annualized pediatric stroke incidence rates, including both neonatal and later childhood stroke and both ischemic and hemorrhagic stroke, range from 3 to 25 per 100 000 children in developed countries. Newborns have the highest risk ratio: 1 in 4000 live births. Stroke is a clinical syndrome. Delays in diagnosis are common in both perinatal and childhood stroke (...) bruit) or a family history suggestive of an autosomal dominant syndrome such as hereditary hemorrhagic telangiectasia (HHT). Management Markedly low platelet counts and coagulation factor deficiencies should be corrected. Large doses of vitamin K may be needed to correct factor deficiencies resulting from maternal medications. Surgical evacuation of a hematoma may reduce extremely high intracranial pressure (ICP) but is rarely performed in neonates, and it is not clear whether surgery improves

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2019 American Heart Association

80. A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology

specimen-based approach, and includes bloodstream and cardiovascular system infections, central nervous system infections, ocular infections, soft tissue infections of the head and neck, upper and lower respiratory infections, infections of the gastrointestinal tract, intra-abdominal infections, bone and joint infections, urinary tract infections, genital infections, and other skin and soft tissue infections; or into etiologic agent groups, including arthropod-borne infections, viral syndromes (...) . Ocular Infections IV. Soft Tissue Infections of the Head and Neck V. Upper Respiratory Tract Bacterial and Fungal Infections VI. Lower Respiratory Tract Infections VII. Infections of the Gastrointestinal Tract VIII. Intra-abdominal Infections IX. Bone and Joint Infections X. Urinary Tract Infections XI. Genital Infections XII. Skin and Soft Tissue Infections XIII. Arthropod-Borne Infections XIV. Viral Syndromes XV. Blood and Tissue Parasite Infections Contents Introduction and Executive Summary I

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2018 Infectious Diseases Society of America

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